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    • 2. 发明申请
    • OBJECTIVE LENS AND OBJECTIVE LENS ADAPTER
    • 目标镜头和目标镜头适配器
    • US20100027132A1
    • 2010-02-04
    • US12509692
    • 2009-07-27
    • Tadashi HIRATA
    • Tadashi HIRATA
    • G02B21/02
    • G02B21/02
    • Especially when observing brain tissue, damage inflicted on the brain tissue is reduced, and light from the brain tissue is collected to the utmost extent. The invention provides an objective lens in which a tip transparent member that is made to contact an observation object is formed to gradually narrow towards an end face thereof, a diameter d of the end face being defined by the following expression, and a maximum diameter D being 3 mm or less: 0 mm≦d−FOV−2×WD×(NA/N)≦0.3 mm where FOV is the observation field of view, WD is the working distance, NA is the numerical aperture, and N is the refractive index of the observation object.
    • 特别是在观察脑组织时,脑组织损伤减轻,脑组织的光被最大限度地收集。 本发明提供了一种物镜,其中使与观察对象接触的尖端透明构件形成为朝向其端面逐渐变窄,端面的直径d由下式定义,最大直径D 为3mm以下:0mmN)其中FOV为观察视野,WD为工作距离,NA为数值孔径,N为观察对象的折射率。
    • 3. 发明申请
    • FOCUS ADJUSTMENT UNIT AND OPTICAL SCANNING MICROSCOPE
    • 聚焦调整单元和光学扫描显微镜
    • US20090073553A1
    • 2009-03-19
    • US12206961
    • 2008-09-09
    • Tadashi HIRATA
    • Tadashi HIRATA
    • G02B21/00G02B21/06
    • G02B21/241G02B21/002G02B21/16
    • An optical scanning microscope is provided in which the observation magnification does not greatly change even when the working distance of an objective lens is changed. The optical scanning microscope includes an objective optical system that converts the light from a specimen into a substantially collimated light beam, an imaging optical system that forms an image from the substantially collimated light beam from the objective optical system at a predetermined position, a pupil projection optical system that substantially collimates the light formed into an image by the imaging optical system at the predetermined position, a lateral scanner that angularly deflects the substantially collimated light beam from the pupil projection optical system to laterally scan the area of the specimen to be observed, and a lens driver that drives the imaging optical system or the pupil projection optical system or both in the optical axis direction. Defining the front side be the side where the specimen is located, the imaging optical system is disposed so that the front focal point thereof is positioned in the vicinity of the back focal point of the objective optical system.
    • 提供了一种光学扫描显微镜,其中即使当物镜的工作距离改变时,观察倍率也不会很大地改变。 光学扫描显微镜包括将来自试样的光转换为基本上准直的光束的物镜光学系统,从预定位置处的物镜光学系统的基本上准直的光束形成图像的成像光学系统,瞳孔投影 光学系统,其基本上准直由成像光学系统在预定位置处形成的图像的光;横向扫描器,其使来自瞳孔投影光学系统的基本准直的光束成角度地偏转以横向扫描待观察的样本的区域, 以及驱动成像光学系统或光瞳投影光学系统或者在光轴方向两者的透镜驱动器。 将前侧定义为试样所在的一侧,成像光学系统设置成使其前焦点位于物镜光学系统的后焦点附近。
    • 4. 发明申请
    • OBJECTIVE-OPTICAL-SYSTEM POSITIONING APPARATUS AND EXAMINATION APPARATUS
    • 目标 - 光学系统定位装置和检查装置
    • US20100309547A1
    • 2010-12-09
    • US12790112
    • 2010-05-28
    • Tadashi HIRATAMasahiro Oba
    • Tadashi HIRATAMasahiro Oba
    • G02B21/02
    • G02B21/0012A61B1/00154A61B1/313A61B1/32A61B2503/40G01N21/01G02B21/02G02B21/248
    • An objective-optical-system positioning apparatus includes a positioning unit interposed between an objective optical system having a small-diameter end section and an examination optical system for examining light collected by the objective optical system; and a substantially cylindrical support unit, one end of which is secured to an organism, and which internally supports the small-diameter end section in a detachable manner. The positioning unit includes a holding part for holding the objective optical system and a moving mechanism supporting the holding part such that the holding part is freely movable in a direction intersecting with a direction of an optical axis of the objective optical system, and the other end of the support unit has a tapered inner surface whose diameter gradually increases toward the tip.
    • 一种物镜光学系统定位装置,包括:位于具有小直径端部的物镜光学系统和用于检查物镜光学系统收集的光的检查光学系统之间的定位单元; 以及一个基本上圆柱形的支撑单元,其一端固定到生物体上,并以可拆卸的方式内部支撑该小直径端部。 定位单元包括用于保持物镜光学系统的保持部件和支撑保持部件的移动机构,使得保持部件能够在与物镜光学系统的光轴方向相交的方向上自由移动,另一端 的支撑单元具有锥形内表面,其直径朝着尖端逐渐增加。
    • 5. 发明申请
    • FOCUS-ADJUSTING UNIT AND MICROSCOPE
    • 聚焦调整单元和微观结构
    • US20090219612A1
    • 2009-09-03
    • US12389875
    • 2009-02-20
    • Tadashi HIRATA
    • Tadashi HIRATA
    • G02B21/00
    • G02B21/244
    • It is possible to use the magnification of an objective lens as is, substantially without changing the observation magnification, even when the working distance of the objective lens is changed. The invention provides a focus-adjusting unit disposed on an optical axis between an objective optical system that collects light from a specimen and an image-forming optical system that images the light collected by the objective optical system at a prescribed position, comprising a front optical system and a back optical system, sequentially disposed along the optical axis direction from a front side, with the objective optical system serving at the front side and the image-forming optical system at the back; and a lens driving part that relatively moves these optical systems in the optical axis direction, wherein the front optical system and the back optical system have refractive powers of different sign and focal lengths of substantially equal absolute value.
    • 即使当物镜的工作距离改变时,也可以基本上不改变观察倍率来使用物镜的放大率。 本发明提供一种聚焦调节单元,其设置在收集来自试样的光的物镜光学系统和将由物镜光学系统收集的光成像到规定位置的图像形成光学系统之间的光轴上,该光学系统包括前光学 系统和背光学系统,其从前侧沿着光轴方向顺序地设置,物镜光学系统在前侧,后方的成像光学系统; 以及透镜驱动部,其在光轴方向上相对移动这些光学系统,其中前光学系统和后光学系统具有基本相等的绝对值的不同符号和焦距的折射力。
    • 6. 发明申请
    • MICROSCOPE EXAMINATION APPARATUS
    • 显微镜检查装置
    • US20080043323A1
    • 2008-02-21
    • US11923138
    • 2007-10-24
    • Hiroya FUKUYAMAYoshihisa TANIKAWATadashi HIRATASeiya TAKAHASHI
    • Hiroya FUKUYAMAYoshihisa TANIKAWATadashi HIRATASeiya TAKAHASHI
    • G02B21/00
    • G02B21/24G02B21/26G02B27/646
    • The invention provides a microscope examination apparatus including a light source; an illumination optical system configured to guide light from the light source to a specimen; an objective lens configured to collimate return light from the specimen, the objective lens being provided in such a manner as to be displaceable at least in a direction intersecting an optical axis of the objective lens; an image-forming lens configured to image the return light from the specimen, which is collimated by the objective lens; an optical detector configured to detect the return light imaged by the image-forming lens; a microscope main body including the image-forming lens and the optical detector; and an objective-lens driving mechanism configured to drive the objective lens in a direction correcting image blur due to a displacement of the specimen.
    • 本发明提供一种包括光源的显微镜检查装置; 照明光学系统,被配置为将来自所述光源的光引导到样本; 物镜,被配置为准直来自所述样本的返回光,所述物镜以至少在与所述物镜的光轴相交的方向可位移的方式设置; 成像透镜,被配置为对由所述物镜准直的来自所述样本的返回光进行成像; 光学检测器,被配置为检测由图像形成透镜成像的返回光; 包括图像形成透镜和光学检测器的显微镜主体; 以及物镜驱动机构,被配置为在校正由于样本的位移造成的图像模糊的方向上驱动物镜。
    • 7. 发明申请
    • VARIABLE-FOCUS OPTICAL SYSTEM
    • 可变焦点光学系统
    • US20120236399A1
    • 2012-09-20
    • US13417814
    • 2012-03-12
    • Tadashi HIRATA
    • Tadashi HIRATA
    • G02B21/02
    • G02B15/163
    • Aberrations are sufficiently corrected, and an excellent image is acquired. Provided is a variable-focus optical system including a positive-power front-group optical system, a rear-group optical system having the same power, and an optical-system driving unit configured to relatively change the distance therebetween in the optical axis direction, wherein the front-group optical system consists of a positive-power first-group optical system formed of a joined lens, that is, a lens L1 and a lens L2, a positive-power second-group optical system consisting of a lens L3, and a third-group optical system formed of a lens L4 and a lens L5, and the rear-group optical system consists of a positive-power fourth-group optical system formed of a lens L7 and a lens L6, a fifth-group optical system consisting of a positive-power lens L8, and a positive-power sixth-group optical system formed of a joined lens, that is, a lens L10 and a lens L9.
    • 畸变被充分校正,并且获得优异的图像。 提供了一种可变焦光学系统,其包括正功率前组光学系统,具有相同功率的后组光学系统和被配置为相对地改变其在光轴方向上的距离的光学系统驱动单元, 其特征在于,所述前组光学系统由接合透镜(即,透镜L1和透镜L2)构成的正功率第一组光学系统,由透镜L3组成的正光二次光学系统, 以及由透镜L4和透镜L5形成的第三组光学系统,并且后组光学系统由由透镜L7和透镜L6形成的正功率第四组光学系统组成,第五组光学 由正功率透镜L8和由接合透镜(即透镜L10和透镜L9)形成的正功率第六组光学系统组成。
    • 8. 发明申请
    • OPTICAL SCANNING OBSERVATION APPARATUS
    • 光学扫描观察装置
    • US20080225388A1
    • 2008-09-18
    • US11948368
    • 2007-11-30
    • Tadashi HIRATA
    • Tadashi HIRATA
    • G02B21/06
    • G02B21/002G02B21/16G02B21/241G02B27/1006G02B27/1066G02B27/141G02B27/145
    • The invention provides a compact optical scanning observation apparatus having an internal focusing mechanism and which is suitable for in-vivo observation of animals. The optical scanning observation apparatus comprises a light source for illuminating a sample; an objective optical system for focusing illumination light onto the sample; a detection-light splitting device for splitting off collected detection light from the illumination light; a detection-light focusing optical system for focusing the split-off detection light; a detector for detecting the focused detection light; a focus scanning device disposed between the detection-light splitting device and the objective optical system; and a lateral-direction scanning device, disposed between the focus scanning device and the objective optical system, for scanning the illumination light from the light source on the sample, in substantially orthogonal directions with respect to the optical axis. The focus scanning device includes a focusing optical system formed of at least a positive lens group and a negative lens group, and a lens driving device for moving at least one lens group included in the focusing optical system to change a working distance of the objective optical system.
    • 本发明提供了一种具有内部聚焦机构并且适用于动物的体内观察的紧凑型光学扫描观察装置。 光学扫描观察装置包括用于照射样品的光源; 用于将照明光聚焦到样品上的物镜光学系统; 检测光分离装置,用于从所述照明光中分离收集的检测光; 用于聚焦分离检测光的检测光聚焦光学系统; 用于检测聚焦检测光的检测器; 设置在检测光分离装置和物镜光学系统之间的聚焦扫描装置; 以及设置在聚焦扫描装置和物镜光学系统之间的横向扫描装置,用于沿着相对于光轴的大致正交的方向扫描来自样品上的光源的照明光。 聚焦扫描装置包括由至少正透镜组和负透镜组构成的聚焦光学系统,以及用于移动聚焦光学系统中包括的至少一个透镜组的透镜驱动装置,以改变物镜的工作距离 系统。
    • 9. 发明申请
    • ALIGNMENT METHOD, ALIGNMENT APPARATUS, AND ALIGNMENT SCREEN FOR OBJECTIVE-LENS GUIDING DEVICE
    • 对准方法,对准设备和用于目标镜头指导设备的对准画面
    • US20080049311A1
    • 2008-02-28
    • US11830692
    • 2007-07-30
    • Tadashi HIRATA
    • Tadashi HIRATA
    • G02B21/00
    • G02B23/2423G02B21/0064G02B21/0076
    • An end face of a narrow-diameter end portion is easily disposed at a correct position on an examination object without setting an examination site, thus enabling rapid and straightforward acquisition of an image of the examination site. The invention provides an alignment method for a guiding device which is attached to an end of an objective lens in such a manner as to be capable of positional adjustment in an optical axis direction and which is brought into contact with an examination target to make a focal position of the objective lens coincident with an examination site. The alignment method comprises securing, to an end face of the guiding device, an alignment screen, having a predetermined pattern; relatively moving the objective lens and the guiding device, to which the alignment screen is secured, in the optical axis direction; fixing relative positions of the objective lens and the guiding device at a position where an in-focus image of the pattern of the alignment screen is obtained, or at a position further relatively shifted by a predetermined distance from that position; and removing the alignment screen from the guiding device.
    • 狭窄端部的端面容易地设置在检查对象的正确位置,而不设置检查位置,从而能够快速且直接地获取检查部位的图像。 本发明提供了一种用于引导装置的对准方法,该引导装置以能够在光轴方向上进行位置调整并与检查对象接触以形成焦点的方式附接到物镜的端部 物镜的位置与检查位置一致。 对准方法包括:将具有预定图案的对准屏固定到引导装置的端面; 将对准屏幕固定在其上的物镜和引导装置相对移动; 将所述物镜和所述引导装置的相对位置固定在获取所述对准画面的图案的对焦图像的位置处,或者与所述位置进一步相对偏移预定距离的位置; 以及从引导装置移除对准屏幕。