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1. 发明授权

US08912246B2 Crosslinkable curing super-branched polyester and cured product and preparation method thereof 有权
标题翻译：可交联固化超支化聚酯和固化产物及其制备方法
公开(公告)号：US08912246B2
公开(公告)日：2014-12-16
申请号：US13885399
申请日：2010-11-15
申请人： Mingdong Yu , Zhi Chen
发明人： Mingdong Yu , Zhi Chen
IPC分类号： C08G61/04 , C08G63/06 , C08G83/00 , C08G63/664 , C08G63/91
CPC分类号： C08G63/664 , C08G63/06 , C08G63/912 , C08G83/005
摘要： A crosslinkable curing super-branched polyester and the cured product and the preparation method thereof are disclosed. The super-branched polyester has high refractive index and comprises a compound represented by the following structural formula (I). In the formula (I), HBP is the backbone of the super-branched polyester; both a and b are positive integers; the sum of a and b is less than or equal to n; n is more than or equal to 10 and less than 80. In the super-branched polyester, A is represented by formula (II) and N is represented by formula (III), wherein R is methyl or hydrogen atom; the mole ratio of N relative to the total mole of A and N is more than 30 mol %, and the ratio of the total mole of A and N relative to the product of the total mole of HBP backbone and n is more than 0.5 and less than or equal to 1.
摘要翻译：公开了一种可交联固化的超支化聚酯和固化产物及其制备方法。超支化聚酯具有高折射率，并且包含由以下结构式（I）表示的化合物。在式（I）中，HBP是超支化聚酯的主链; a和b都是正整数; a和b的和小于或等于n; 在超支化聚酯中，A由式（II）表示，N由式（III）表示，其中R是甲基或氢原子; N相对于A和N的总摩尔数的摩尔比大于30mol％，A和N的总摩尔数相对于HBP主链和n的总摩尔数的乘积的比率大于0.5，小于或等于1。

2. 发明申请

US20130237627A1 CROSSLINKABLE CURING SUPER-BRANCHED POLYESTER AND CURED PRODUCT AND PREPARATION METHOD THEREOF 有权
标题翻译：可交联固化超分散聚酯和固化产品及其制备方法
公开(公告)号：US20130237627A1
公开(公告)日：2013-09-12
申请号：US13885399
申请日：2010-11-15
申请人： Mingdong Yu , Zhi Chen
发明人： Mingdong Yu , Zhi Chen
IPC分类号： C08G63/664
CPC分类号： C08G63/664 , C08G63/06 , C08G63/912 , C08G83/005
摘要： A crosslinkable curing super-branched polyester and the cured product and the preparation method thereof are disclosed. The super-branched polyester has high refractive index and comprises a compound represented by the following structural formula (I). In the formula (I), HBP is the backbone of the super-branched polyester; both a and b are positive integers; the sum of a and b is less than or equal to n; n is more than or equal to 10 and less than 80. In the super-branched polyester, A is represented by formula (II) and N is represented by formula (III), wherein R is methyl or hydrogen atom; the mole ratio of N relative to the total mole of A and N is more than 30 mol %, and the ratio of the total mole of A and N relative to the product of the total mole of HBP backbone and n is more than 0.5 and less than or equal to 1.
摘要翻译：公开了一种可交联固化的超支化聚酯和固化产物及其制备方法。超支化聚酯具有高折射率，并且包含由以下结构式（I）表示的化合物。在式（I）中，HBP是超支化聚酯的主链; a和b都是正整数; a和b的和小于或等于n; 在超支化聚酯中，A由式（II）表示，N由式（III）表示，其中R是甲基或氢原子; N相对于A和N的总摩尔数的摩尔比大于30mol％，A和N的总摩尔数相对于HBP主链和n的总摩尔数的乘积的比率大于0.5，小于或等于1。

3. 发明申请

US20120184542A1 PYRIDO PYRIMIDINES 审中-公开
标题翻译：吡咯烷基吡啶
公开(公告)号：US20120184542A1
公开(公告)日：2012-07-19
申请号：US13348665
申请日：2012-01-12
申请人： Kevin Anderson , Yi Chen , Zhi Chen , Kin-Chun Luk , Pamela Loreen Rossman , Hongmao Sun , Peter Michael Wovkulich
发明人： Kevin Anderson , Yi Chen , Zhi Chen , Kin-Chun Luk , Pamela Loreen Rossman , Hongmao Sun , Peter Michael Wovkulich
IPC分类号： A61K31/519 , A61K31/5377 , A61P25/00 , A61K31/5386 , A61P35/00 , A61P25/28 , C07D471/04 , C07D519/00
CPC分类号： C07D471/04
摘要： Compounds of formula and pharmaceutically acceptable salts thereof are described, as well as the pharmaceutical compositions containing said compounds and their pharmaceutically acceptable salts, and the use of said compounds and pharmaceutical compositions for the treatment, control or amelioration of proliferative diseases, including cancer, Down syndrome or early onset Alzheimer's disease.
摘要翻译：本发明描述了式及其药学上可接受的盐的化合物，以及含有所述化合物及其药学上可接受的盐的药物组合物，以及所述化合物和药物组合物用于治疗，控制或改善增殖性疾病（包括癌症）Down 综合征或早发性阿尔茨海默氏病。

4. 发明授权

US07851594B2 Human cytokine receptor 有权
公开(公告)号：US07851594B2
公开(公告)日：2010-12-14
申请号：US11829011
申请日：2007-07-26
申请人： Scott R. Presnell , Wenfeng Xu , Wayne Kindsvogel , Zhi Chen , Steven D. Hughes
发明人： Scott R. Presnell , Wenfeng Xu , Wayne Kindsvogel , Zhi Chen , Steven D. Hughes
IPC分类号： C07K14/52
CPC分类号： C07K14/715 , A61K38/00
摘要： Cytokines and their receptors have proven usefulness in both basic research and as therapeutics. The present invention provides a new human cytokine receptor designated as “Zcytor16.”

5. 发明授权

US07638602B2 Human cytokine receptor 有权
公开(公告)号：US07638602B2
公开(公告)日：2009-12-29
申请号：US11782545
申请日：2007-07-24
申请人： Scott R. Presnell , Wenfeng Xu , Wayne Kindsvogel , Zhi Chen
发明人： Scott R. Presnell , Wenfeng Xu , Wayne Kindsvogel , Zhi Chen
IPC分类号： C07K14/705
CPC分类号： C07K14/715 , A61K38/00 , C07K2319/00
摘要： Cytokines and their receptors have proven usefulness in both basic research and as therapeutics. The present invention provides a new human cytokine receptor designated as “Zcytor16.”

6. 发明申请

US20090264624A1 HUMAN CYTOKINE RECEPTOR 有权
标题翻译：人体细胞因子受体
公开(公告)号：US20090264624A1
公开(公告)日：2009-10-22
申请号：US12435218
申请日：2009-05-04
申请人： Scott R. Presnell , Wenfeng Xu , Wayne Kindsvogel , Zhi Chen , Steven D. Hughes
发明人： Scott R. Presnell , Wenfeng Xu , Wayne Kindsvogel , Zhi Chen , Steven D. Hughes
IPC分类号： C07K14/715
CPC分类号： C07K14/715 , A61K38/00
摘要： Cytokines and their receptors have proven usefulness in both basic research and as therapeutics. The present invention provides a new human cytokine receptor designated as “Zcytor16.”
摘要翻译：细胞因子及其受体已被证明在基础研究和治疗方面都是有用的。本发明提供了称为“Zcytor16”的新的人细胞因子受体。

7. 发明申请

US20090108377A1 Method for fabricating gate dielectrics of metal-oxide-semiconductor transistors using rapid thermal processing 审中-公开
标题翻译：使用快速热处理制造金属氧化物半导体晶体管的栅极电介质的方法
公开(公告)号：US20090108377A1
公开(公告)日：2009-04-30
申请号：US11977258
申请日：2007-10-24
申请人： Zhi Chen , Jun Guo
发明人： Zhi Chen , Jun Guo
IPC分类号： H01L29/78 , H01L21/31
CPC分类号： H01L21/02236 , H01L21/0214 , H01L21/02148 , H01L21/02164 , H01L21/0217 , H01L21/02181 , H01L21/022 , H01L21/02247 , H01L21/02252 , H01L21/02255 , H01L21/02266 , H01L21/0228 , H01L21/02282 , H01L21/28185 , H01L21/28202 , H01L21/31604 , H01L21/3165 , H01L29/517 , H01L29/518 , H01L29/78
摘要： In a method for fabricating gate dielectrics of metal-oxide-semiconductor transistors, rapid thermal processing (RTP) of a gate dielectric material is performed at a temperature from 1000-1200° C. in a low-concentration oxidizing gas. The method regrows an oxide layer having a thickness of more than 0.05 nm between the gate dielectric layer and the channel region that reduces gate leakage current by 2-5 orders of magnitude and improves hot-electron reliability due to phonon-energy-coupling enhancement (PECE) effect.
摘要翻译：在制造金属氧化物半导体晶体管的栅极电介质的方法中，在低浓度氧化气体中，在1000-1200℃的温度下进行栅极介电材料的快速热处理（RTP）。该方法在栅电介质层和沟道区之间再生厚度大于0.05nm的氧化物层，其将栅极漏电流减少2-5个数量级，并且由于声子能量耦合增强而改善热电子可靠性（ PECE）效果。

8. 发明授权

US07393684B2 Immunoconjugates of anti-IL-20 antibodies and hybridoma cell lines expressing anti-IL-20 antibodies 有权
标题翻译：抗IL-20抗体的免疫偶联物和表达抗IL-20抗体的杂交瘤细胞系
公开(公告)号：US07393684B2
公开(公告)日：2008-07-01
申请号：US10994116
申请日：2004-11-19
申请人： Wenfeng Xu , Wayne R. Kindsvogel , Zhi Chen , Steven D. Hughes , Yasmin A. Chandrasekher , Stacey R. Dillon , Joyce M. Lehner , Anthony W. Siadak , Pallavur V. Sivakumar , Margaret D. Moore
发明人： Wenfeng Xu , Wayne R. Kindsvogel , Zhi Chen , Steven D. Hughes , Yasmin A. Chandrasekher , Stacey R. Dillon , Joyce M. Lehner , Anthony W. Siadak , Pallavur V. Sivakumar , Margaret D. Moore
IPC分类号： C12N5/20
CPC分类号： C07K16/2866 , A61K38/1793 , A61K38/20 , A61K47/60 , A61K2039/505 , C07K14/54 , C07K14/7155 , C07K16/244 , C07K2317/73 , C07K2317/76 , C07K2319/30
摘要： The present invention relates to blocking the activity of IL-20 polypeptide molecules. IL-20 is a cytokine that is involved in inflammatory processes and human disease. IL-20RA/IL-20RB is a common receptor for IL-20. The present invention includes anti-IL-20 antibodies and binding partners, as well as methods for antagonizing IL-20 using such antibodies and binding partners.
摘要翻译：本发明涉及阻断IL-20多肽分子的活性。 IL-20是涉及炎症过程和人类疾病的细胞因子。 IL-20RA / IL-20RB是IL-20的常见受体。本发明包括抗IL-20抗体和结合配偶体，以及使用这种抗体和结合配偶体拮抗IL-20的方法。

9. 发明申请

US20080131931A1 MOUSE CYTOKINE RECEPTOR ZCYTOR16 审中-公开
标题翻译：小鼠细胞因子受体ZCYTOR16
公开(公告)号：US20080131931A1
公开(公告)日：2008-06-05
申请号：US12016817
申请日：2008-01-18
申请人： Scott R. Presnell , Wenfeng Xu , Wayne Kindsvogel , Zhi Chen
发明人： Scott R. Presnell , Wenfeng Xu , Wayne Kindsvogel , Zhi Chen
IPC分类号： C12P21/04 , C07H21/04 , C12N15/00 , C12N1/20 , C12N1/00 , C12N5/06 , C12N5/00 , C12N5/10
CPC分类号： C07K14/7155 , A01K2217/05 , A01K2217/075 , C07K2319/00 , Y10S530/81
摘要： Cytokines and their receptors have proven usefulness in both basic research, animal models, and as therapeutics. The present invention provides polynucleotides encoding a new cytokine receptor designated as “mouse Zcytor16”, which can bind and antagonize the IL-TIF cytokine. The present invention also provides corresponding vectors, cells, and methods of production.
摘要翻译：细胞因子及其受体已被证明在基础研究，动物模型和治疗中都是有用的。本发明提供编码称为“小鼠Zcytor16”的新细胞因子受体的多核苷酸，其可以结合并拮抗IL-TIF细胞因子。本发明还提供相应的载体，细胞和生产方法。

10. 发明授权

US07351555B2 Mouse cytokine receptor Zcytor16 失效
标题翻译：小鼠细胞因子受体Zcytor16
公开(公告)号：US07351555B2
公开(公告)日：2008-04-01
申请号：US11045944
申请日：2005-01-28
申请人： Scott R. Presnell , Wenfeng Xu , Wayne Kindsvogel , Zhi Chen
发明人： Scott R. Presnell , Wenfeng Xu , Wayne Kindsvogel , Zhi Chen
IPC分类号： C12N15/12 , C12N5/10 , C12P21/02
CPC分类号： C07K14/7155 , A01K2217/05 , A01K2217/075 , C07K2319/00 , Y10S530/81
摘要： Cytokines and their receptors have proven usefulness in both basic research, animal models, and as therapeutics. The present invention provides a new cytokine receptor designated as “mouse Zcytor16,” which can bind and antagonize the IL-TIF cytokine.
摘要翻译：细胞因子及其受体已被证明在基础研究，动物模型和治疗中都是有用的。本发明提供了称为“小鼠Zcytor16”的新的细胞因子受体，其可以结合并拮抗IL-TIF细胞因子。

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