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1. 发明申请

US20100318147A1 MEDICAL DEVICE FOR STIMULATION OF THE HIS BUNDLE 有权
标题翻译：用于刺激他们的医疗设备
公开(公告)号：US20100318147A1
公开(公告)日：2010-12-16
申请号：US12808190
申请日：2007-12-18
申请人： Mikael Forslund , Johan Eckerdal
发明人： Mikael Forslund , Johan Eckerdal
IPC分类号： A61N1/05 , A61N1/362 , A61N1/08 , A61N1/365 , A61N1/37
CPC分类号： A61N1/0573 , A61N1/0587
摘要： An implantable medical system for delivering pacing pulses to HIS bundle of a heart of a patient when implanted in said patient includes a medical lead, which is adapted to be attached with a distal end to tissue of said heart, including a at least two electrodes arranged being electrically separated from each other. The implantable medical device connectable to the medical lead includes a pacing circuit adapted to deliver the pacing pulses to said heart via the medical lead, a selection device connected between the pacing circuit and the electrodes adapted to selectively activate at least one of said electrodes, and a processing device adapted to control the selection device to selectively activate at least one of the electrodes to direct the pacing pulses to the HIS bundle.
摘要翻译：一种可植入医疗系统，用于在植入患者心脏时向患者的心脏的HIS束输送起搏脉冲包括医用引线，其适于与远端结合到所述心脏的组织，所述远端包括至少两个电极，彼此电隔离。可连接到医疗引线的可植入医疗装置包括适于经由医用引线将起搏脉冲输送到心脏的起搏电路，连接在起搏电路和电极之间的选择装置，其适于选择性地激活所述电极中的至少一个，以及处理装置，其适于控制所述选择装置选择性地激活所述电极中的至少一个以将所述起搏脉冲引导到所述HIS束。

2. 发明授权

US08560068B2 Medical device for stimulation of the HIS bundle 有权
标题翻译：用于刺激HIS束的医疗装置
公开(公告)号：US08560068B2
公开(公告)日：2013-10-15
申请号：US12808190
申请日：2007-12-18
申请人： Mikael Forslund , Johan Eckerdal
发明人： Mikael Forslund , Johan Eckerdal
IPC分类号： A61N1/00
CPC分类号： A61N1/0573 , A61N1/0587
摘要： An implantable medical system for delivering pacing pulses to HIS bundle of a heart of a patient when implanted in said patient includes a medical lead, which is adapted to be attached with a distal end to tissue of said heart, including a at least two electrodes arranged being electrically separated from each other. The implantable medical device connectable to the medical lead includes a pacing circuit adapted to deliver the pacing pulses to said heart via the medical lead, a selection device connected between the pacing circuit and the electrodes adapted to selectively activate at least one of said electrodes, and a processing device adapted to control the selection device to selectively activate at least one of the electrodes to direct the pacing pulses to the HIS bundle.
摘要翻译：一种可植入医疗系统，用于在植入患者心脏时向患者的心脏的HIS束输送起搏脉冲包括医用引线，其适于与远端结合到所述心脏的组织，所述远端包括至少两个电极，彼此电隔离。可连接到医疗引线的可植入医疗装置包括适于经由医用引线将起搏脉冲输送到心脏的起搏电路，连接在起搏电路和电极之间的选择装置，其适于选择性地激活所述电极中的至少一个，以及处理装置，其适于控制所述选择装置选择性地激活所述电极中的至少一个以将所述起搏脉冲引导到所述HIS束。

3. 发明授权

US08700153B2 Cardiac stimulating device 有权
标题翻译：心脏刺激装置
公开(公告)号：US08700153B2
公开(公告)日：2014-04-15
申请号：US13509556
申请日：2009-12-08
申请人： Johan Eckerdal
发明人： Johan Eckerdal
IPC分类号： A61N1/00
CPC分类号： A61N1/37276 , A61N1/3622 , A61N1/3688 , A61N1/371
摘要： An implantable medical device, IMD, comprises atrial and ventricular sensing units for sensing atrial or ventricular electric events. The IMD also comprises atrial and ventricular pulse generators for generating atrial or ventricular pacing pulses. A controller controls the operation of the IMD (100) according to a first mode, in which the ventricular pulse generator is prevented from generating a back-up pulse if an evoked response detector fails to detect evoked response to a delivered ventricular pacing pulse, and a second mode, in which the ventricular pulse generator is controlled to generate a back-up pulse if no evoked response is detected following delivery of a ventricular stimulating pulse. The controller switches operation from the first mode to the second mode based on the evoked response detector failing to detect an evoked response to a delivered ventricular pacing pulse.
摘要翻译：可植入医疗装置IMD包括用于感测心室或心室电事件的心房和心室感测单元。 IMD还包括用于产生心房或心室起搏脉冲的心房和心室脉冲发生器。控制器根据第一模式控制IMD（100）的操作，其中如果诱发的响应检测器不能检测对所传送的心室起搏脉冲的诱发响应，则防止心室脉冲发生器产生备用脉冲，以及第二模式，其中如果在递送心室刺激脉冲之后没有检测到诱发反应，则控制心室脉冲发生器以产生备用脉冲。控制器基于诱发响应检测器未能检测到对所输送的心室起搏脉冲的诱发反应，将操作从第一模式切换到第二模式。

4. 发明授权

US07242980B2 Implantable heart stimulator with infection control current, employing counter electrode 有权
标题翻译：具有感染控制电流的植入式心脏刺激器，采用对电极
公开(公告)号：US07242980B2
公开(公告)日：2007-07-10
申请号：US10468589
申请日：2002-02-26
申请人： Johan Eckerdal , Martin Obel , Eva Micski
发明人： Johan Eckerdal , Martin Obel , Eva Micski
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N1/375
摘要： An implantable heart stimulator has a pulse generator, implantable in a subcutaneous pocket, and an electrode lead connected thereto for delivering stimulation pulses to a patient's heart. The pulse generator has an electrically conductive housing, and the electrode lead has a proximal portion which after implantation, extends substantially from the housing to a location situated beyond entry into the venous system and before entry into the superior vena cava. The proximal portion has an exterior with an electrically conductive surface, which together with the housing, form an infection control current electrode. A counter electrode is disposed outside of the subcutaneous pocket, and a current source supplies an infection control current between the infection control current electrode and the counter electrode for counteracting bacterial growth at least on an exterior of the housing.
摘要翻译：可植入心脏刺激器具有脉冲发生器，可植入在皮下袋中，以及连接到其上的电极引线，用于将刺激脉冲输送到患者的心脏。脉冲发生器具有导电壳体，并且电极引线具有近端部分，其在植入之后基本上从壳体延伸到位于超出进入静脉系统并且在进入上腔静脉之前的位置。近端部分具有带导电表面的外部，其与壳体一起形成感染控制电流电极。对置电极设置在皮下袋的外侧，并且电流源至少在外壳的外部上在感染控制电流电极和对电极之间提供感染控制电流，以抵消细菌生长。

5. 发明申请

US20100280563A1 DEVICE AND METHOD FOR DETECTING AND TREATING A MYOCARDIAL INFARCTION USING PHOTOBIOMODULATION 审中-公开
标题翻译：检测和治疗使用光合作用的心肌梗塞的装置和方法
公开(公告)号：US20100280563A1
公开(公告)日：2010-11-04
申请号：US12528363
申请日：2007-02-28
申请人： Anne Norlin-Weissenrieder , Leda Henriquez , Hans Strandberg , Eva Hartström , Mikael Sjögren , Annika Naeslund , Johan Eckerdal
发明人： Anne Norlin-Weissenrieder , Leda Henriquez , Hans Strandberg , Eva Hartström , Mikael Sjögren , Annika Naeslund , Johan Eckerdal
IPC分类号： A61N1/362
CPC分类号： A61N1/36521 , A61B5/0422 , A61B5/0452 , A61B5/053 , A61B5/6846 , A61B5/7239 , A61N1/36557 , A61N1/3702 , A61N5/0601 , A61N2005/063 , A61N2005/0652 , A61N2005/0659 , A61N2005/067
摘要： In an implantable medical device and a method for treating cardiac tissue of a heart of a patient with therapeutic light, a myocardial infarction is detected and a location the myocardial infarction is identified. A therapy session is initiated by selectively activating one or more of a number of light emitting units arranged in at least one medical lead connectable to the implantable medical device, to emit therapeutic light toward the detected location of the myocardial infarction upon detection of an occurrence of the myocardial infarction.
摘要翻译：在可植入医疗装置和用治疗光治疗患者心脏的心脏组织的方法中，检测到心肌梗塞并确定心肌梗塞的位置。通过选择性地激活布置在可连接到可植入医疗装置的至少一个医疗引线中的多个发光单元中的一个或多个来发起治疗会话，以便在检测到发生心肌梗死的发生时向被检测的心肌梗死位置发射治疗光心肌梗塞。

6. 发明申请

US20100137957A1 MEDICAL IMPLANTABLE LEAD 有权
标题翻译：医用植入式铅
公开(公告)号：US20100137957A1
公开(公告)日：2010-06-03
申请号：US12597768
申请日：2007-04-27
申请人： Johan Eckerdal
发明人： Johan Eckerdal
IPC分类号： A61N1/05
CPC分类号： A61N1/0565 , A61N1/0573
摘要： A medical implantable lead has a proximal end and a distal end, a biostable and biocompatible polymeric header, which is arranged at the distal end and has a first tubular portion, a helical fixation element located within the first tubular portion and being extendable from a distal end of the header, and a radiopaque ring. The header further has a second tubular portion, which is arranged coaxially of the first tubular portion and is attached to the first tubular portion at a distal end of the second tubular portion, while having a free proximal end. The tubular portions form a circumferential pocket, wherein the first tubular portion extends from the proximal end of the header at least to said distal end of the second tubular portion. The radiopaque ring is arranged around the first tubular portion and is received in the circumferential pocket.
摘要翻译：医用可植入引线具有近端和远端，生物稳定和生物相容的聚合物集管，其布置在远端并且具有第一管状部分，螺旋固定元件，位于第一管状部分内并且可从远端头部的末端和不透射线的环。头部还具有第二管状部分，其与第一管状部分同轴设置，并且在第二管状部分的远端处附接到第一管状部分，同时具有自由近端。管状部分形成周向袋，其中第一管状部分从头部的近端至少延伸到第二管状部分的所述远端。不透射线环设置在第一管状部分周围并被容纳在周向袋中。

7. 发明授权

US07860581B2 Implantable lead with a stimulating electrode and a mapping electrode that is electrically disconnectable 有权
标题翻译：具有刺激电极的可植入引线和可电断开的映射电极
公开(公告)号：US07860581B2
公开(公告)日：2010-12-28
申请号：US12090982
申请日：2005-10-31
申请人： Johan Eckerdal , Kenneth Dahlberg
发明人： Johan Eckerdal , Kenneth Dahlberg
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N1/0573
摘要： An implantable lead for delivering electrical stimuli to a human heart has a stimulating electrode for transmitting electrical stimuli to the myocardium after implantation, and a mapping electrode for use during implantation. The mapping electrode is configured to deliver electrical stimuli to the heart and to sense intrinsic cardiac activity, for the purpose of finding a suitable fixation position in the myocardium. During the implantation procedure, the mapping electrode is electrically connected to the conductor. The lead is configured to electrically disconnect the mapping electrode from the conductor after a suitable fixation position has been determined.
摘要翻译：用于将电刺激递送到人的心脏的可植入引线具有刺激电极，用于在植入后将电刺激传输到心肌，以及用于植入期间的映射电极。映射电极被配置为向心脏递送电刺激并感测内在的心脏活动，以便在心肌中找到合适的固定位置。在植入过程期间，映射电极电连接到导体。引线构造成在已经确定了合适的固定位置之后电连接映射电极与导体。

8. 发明申请

US20100036228A1 SUTURE SLEEVE AND A METHOD FOR IMPLANTING ONE OR MORE ELECTRICAL LEADS INTO A VEIN 审中-公开
标题翻译：固定套管和将一个或多个电气导线插入到一个VEIN中的方法
公开(公告)号：US20100036228A1
公开(公告)日：2010-02-11
申请号：US12531719
申请日：2007-03-26
申请人： Johan Eckerdal , Rolf Hill
发明人： Johan Eckerdal , Rolf Hill
IPC分类号： A61B5/04
CPC分类号： A61N1/057 , A61N2001/0582
摘要： In a suture sleeve and implantation method for one or more implantable leads, the suture sleeve is adapted to be inserted into a vein to secure and protect the one or more leads from damage when a suture thread is positioned and tied around the vein in the region over the suture sleeve to secure the suture sleeve and prevent bleeding from the vein. The suture sleeve has two or more lead receiving through holes into each of which a medical implantable lead may be inserted. The suture sleeve is formed such that at least all of the holes except one are provided with sealing means, which easily can be broken or removed when inserting a lead into the hole such that, when inserted into a vein, bleeding is prevented from a through hole of the sleeve by the sealing means even if no lead is positioned in the hole. The invention also relates to a method for implanting one or more electrical leads into a vein.
摘要翻译：在用于一个或多个可植入引线的缝合套管和植入方法中，当缝合线被定位并围绕该区域中的静脉绑扎时，缝合套筒适于插入静脉中以固定和保护一个或多个引线免受损伤穿过缝合套以固定缝合套，并防止静脉出血。缝合套管具有两个或更多个引线接收通孔，每个可插入医用可植入引线。缝合套筒形成为使得除了一个之外的至少所有孔都设置有密封装置，当将铅插入孔中时容易破裂或去除，使得当插入静脉时，防止出血通过即使没有铅定位在孔中，密封装置的套筒孔也是如此。本发明还涉及将一个或多个电引线植入静脉中的方法。

9. 发明申请

US20090177145A1 MEDICAL DEVICE AND METHOD FOR MONITORING HEMATOCRIT AND SVO2 审中-公开
标题翻译：医疗装置和监测HEMATOCRIT和SVO2的方法
公开(公告)号：US20090177145A1
公开(公告)日：2009-07-09
申请号：US12373356
申请日：2007-02-22
申请人： Malin Ohlander , Kjell Noren , Johan Eckerdal , Mika Hietanen , Kenth Nilsson , Urban Lonn
发明人： Malin Ohlander , Kjell Noren , Johan Eckerdal , Mika Hietanen , Kenth Nilsson , Urban Lonn
IPC分类号： A61M37/00 , G06Q50/00 , A61B5/1459 , A61B5/02
CPC分类号： A61B5/02055 , A61B5/0086 , A61B5/053 , A61B5/0538 , A61B5/14535 , A61N1/36521 , G06Q50/22
摘要： A method, an implantable medical device, and a computer-readable medium encoded with programming instructions allow monitoring of a hematocrit value and an SvO2 level of a patient, making use of at least one medical lead connected to an implantable medical device that carries an optical sensor module that measures at least one hematocrit value and at least one SvO2 value using at least first, second and third light radiation wavelengths, by determining a present hematocrit value from at least one of the measured hematocrit values and determining a present SvO2 value from at least one of the measured SvO2 values, and determining a patient status by evaluating the present hematocrit value and the present SvO2 value, to allow a change in the patient status to be identified.
摘要翻译：一种方法，可植入医疗装置和用程序指令编码的计算机可读介质允许监测患者的血细胞比容值和SvO2水平，利用连接到可植入医疗装置的至少一个医疗引线，该医用引线携带光学传感器模块，其通过使用至少第一，第二和第三光辐射波长测量至少一个血细胞比容值和至少一个SvO2值，通过从所测量的血细胞比容值中的至少一个确定目前的血细胞比容值，并从测量的SvO2值中的至少一个，以及通过评估当前血细胞比容值和当前SvO2值来确定患者状态，以允许识别患者状态的改变。

10. 发明授权

US07203550B2 Implantable medical device with a current generated for infection control 失效
标题翻译：植入式医疗器械具有感染控制产生的电流
公开(公告)号：US07203550B2
公开(公告)日：2007-04-10
申请号：US10468867
申请日：2002-02-26
申请人： Mark Kroll , Johan Eckerdal , Martin Obel , Eva Micski
发明人： Mark Kroll , Johan Eckerdal , Martin Obel , Eva Micski
IPC分类号： A61N1/00 , A61B19/00 , B65B55/02
CPC分类号： A61N1/375 , A61N1/056 , A61N1/326 , A61N1/3962
摘要： In a cardiac stimulating device, an infection control current is generated and applied to a subject in whom a medical device is implanted by completing a circuit including an entirely electrically conductive exterior of a housing of the device, an electrode carried by an electrode lead of the device, and an electrically conductive surface of a proximal portion of the electrode lead, extending from the housing to a location, after implantation, situated beyond entry of the electrode lead into the venous system and before entry of the electrode lead into the superior vena cava. The infection control current can be a current with a square waveform, and the circuit can be completed at selected times, such as only during the refractory period of the subject's heart.
摘要翻译：在心脏刺激装置中，通过完成包括装置的外壳的完全导电外部的电路，产生感染控制电流并将其施加到其中植入医疗装置的对象，由电极引线承载的电极器件和电极引线的近端部分的导电表面，从壳体延伸到植入后的位置，其位于超过电极引线进入静脉系统之内并且在电极引线进入上腔静脉之前。感染控制电流可以是具有方波形的电流，并且电路可以在选定的时间完成，例如仅在受试者心脏的不应期期间完成。

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