会员体验
专利管家(专利管理)
工作空间(专利管理)
风险监控(情报监控)
数据分析(专利分析)
侵权分析(诉讼无效)
联系我们
交流群
官方交流:
QQ群: 891211   
微信请扫码    >>>
现在联系顾问~
热词
    • 3. 发明申请
    • Human-powered dry powder inhaler and dry powder inhaler compositions
    • 人造干粉吸入器和干粉吸入器组合物
    • US20080035143A1
    • 2008-02-14
    • US11893040
    • 2007-08-14
    • Robert SieversJessica BestStephen Cape
    • Robert SieversJessica BestStephen Cape
    • A61M15/00A61K9/127A61M13/00
    • A61M15/00A61K9/0075A61K9/1623A61K9/1652A61M11/003A61M11/008A61M15/0086A61M15/0088A61M16/0078A61M16/0084A61M16/0093A61M16/1055A61M16/1065A61M2202/064
    • In one embodiment, a human-powered dry powder inhaler comprises a human-powered compressible component operable to discharge an air pulse at an outlet at a pressure of about 1-40 psi; an inflatable reservoir operable to receive an air pulse discharged from the human-powered compressible component to provide an aerosol of a dry powder pharmaceutical formulation in the reservoir, the reservoir including an outlet valve; and a receiving mask in communication with the outlet valve and operable to receive an aerosol of dry powder from the reservoir and to deliver the aerosol to at least a mouth or nose of a patient. In another embodiment, the inhaler comprises a human-powered compressible component operable to discharge an air pulse at an outlet of a polymeric pressure release valve at a pressure of about 1-40 psi; and a receiving mask in communication with the outlet of the compressible component and operable to deliver an aerosol of dry powder to at least a mouth or nose of a patient. Methods for delivery of a dry powder pharmaceutical formulation to a patient are conducted in the absence of electrical power and circuitry and pre-pressurized propellant gas. Suitable dry powder pharmaceutical formulations may include myo-inositol and/or maltodextrin as a carrier and active ingredients such as vaccines or siRNA.
    • 在一个实施例中,人力干粉吸入器包括人力动力可压缩部件,其可操作以在约1-40psi的压力下排出出口处的空气脉冲; 充气储存器,其可操作以接收从人力可压缩部件排出的空气脉冲,以在储存器中提供干粉末药物制剂的气溶胶,所述储存器包括出口阀; 以及与所述出口阀连通并且可操作以从所述储存器接收干燥粉末的气溶胶并将所述气溶胶输送到患者的至少一个口或鼻部的接收面罩。 在另一个实施例中,吸入器包括人力动力的可压缩部件,其可操作以在约1-40psi的压力下排出聚合物压力释放阀的出口处的空气脉冲; 以及接收面罩,其与所述可压缩部件的出口连通并且可操作以将干粉的气溶胶输送到患者的至少一个口或鼻部。 在没有电力和电路和预加压推进剂气体的情况下,将干粉药物制剂递送到患者的方法进行。 合适的干粉药物制剂可以包括肌醇和/或麦芽糖糊精作为载体和活性成分例如疫苗或siRNA。