专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20050089553A1 Method and apparatus for reducing the incidence of tobacco use 失效
标题翻译：减少烟草使用发生率的方法和设备
公开(公告)号：US20050089553A1
公开(公告)日：2005-04-28
申请号：US10971224
申请日：2004-10-21
申请人： Michel Cormier , Robert Gale , Andrew Scott
发明人： Michel Cormier , Robert Gale , Andrew Scott
IPC分类号： A61M37/00 , A61F9/02 , A61F13/02 , A61M31/00
CPC分类号： A61K9/0021 , A61M37/0015 , A61M2037/0023 , A61M2037/0038 , A61M2037/0046
摘要： An apparatus for transdermally delivering a nicotine-based agent to a tobacco or nicotine user comprising a microprojection member having a plurality of microprojections that are adapted to pierce the stratum corneum of the tobacco user, the microprojection member having a biocompatible coating disposed thereon that includes a nicotine-based agent.
摘要翻译：一种用于将烟碱基药物经皮递送至烟草或尼古丁使用者的装置，其包括具有适于刺穿烟草使用者的角质层的多个微突出物的微突出物构件，所述微突出物构件具有布置在其上的生物相容性涂层，尼古丁为主剂。

2. 发明申请

US20070082038A1 Transdermal nicotine salt delivery system 有权
标题翻译：透皮尼古丁盐输送系统
公开(公告)号：US20070082038A1
公开(公告)日：2007-04-12
申请号：US11525977
申请日：2006-09-22
申请人： Robert Gale , Jay Audett , Rama Padmanabhan , Michel Cormier , Allison Luciano , Eric Silverberg , Paul Foreman
发明人： Robert Gale , Jay Audett , Rama Padmanabhan , Michel Cormier , Allison Luciano , Eric Silverberg , Paul Foreman
IPC分类号： A61K31/4439 , A61K9/70
CPC分类号： A61K9/7061 , A61K31/4439 , A61K31/56 , C09J7/255 , C09J7/385 , C09J133/06 , C09J2467/006
摘要： A transdermal nicotine salt delivery system to an individual. The system has a high nicotine salt loading to effect therapeutic flux rate. Acrylate polymeric drug reservoir with the high nicotine salt dissolved therein provides desirable adhesive characteristics and effective transdermal therapeutic properties.
摘要翻译：向个体透皮的尼古丁盐输送系统。该系统具有高尼古丁盐负荷以实现治疗通量。溶解有高尼古丁盐的丙烯酸酯聚合物药物储库提供了所需的粘合特性和有效的经皮治疗性质。

3. 发明申请

US20050186277A1 Novel formulations for the administration of fluoxetine 审中-公开
标题翻译：用于氟西汀治疗的新型配方
公开(公告)号：US20050186277A1
公开(公告)日：2005-08-25
申请号：US11082141
申请日：2005-03-15
申请人： Robert Gale , Melinda Nelson , Michel Cormier , Suneel Gupta , Patricia Campbell
发明人： Robert Gale , Melinda Nelson , Michel Cormier , Suneel Gupta , Patricia Campbell
IPC分类号： A61K9/70 , A61K31/135 , A61K31/138 , A61K31/57 , A61K31/573 , A61K31/137
CPC分类号： A61K9/7084 , A61K31/135 , A61K31/138 , A61K31/57 , A61K2300/00
摘要： Composition of matter for application to a body surface or membrane to administer fluoxetine by permeation through the body surface or membrane, the composition comprising fluoxetine to be administered, at a therapeutically effective rate, alone or in combination with a permeation enhancer or mixture. A preferred embodiment is directed to the transdermal administration of fluoxetine at reduced skin irritation levels wherein fluoxetine, preferably provided as fluoxetine acetate, is coadministered with a corticosteroid such as hydrocortisone. Also disclosed are drug delivery devices containing the fluoxetine or fluoxetine and enhancer composition and methods for the transdermal administration of the fluoxetine and fluoxetine/enhancer composition.
摘要翻译：用于通过穿过身体表面或膜透过体外表面或膜施用氟西汀的物质的组成，所述组合物包含单独或与渗透促进剂或混合物组合的待施用氟西汀。优选的实施方案涉及在减少的皮肤刺激水平下透皮给药氟西汀，其中氟西汀，优选以醋酸氟西汀提供，与皮质类固醇如氢化可的松共同施用。还公开了含有氟西汀或氟西汀和增强剂组合物的药物递送装置和用于透皮给药氟西汀和氟西汀/增强剂组合物的方法。

4. 发明申请

US20070100274A1 Transdermal Electrotransport Delivery Device Including An Antimicrobial Compatible Reservoir Composition 有权
标题翻译：透皮电传递装置包括一种抗微生物兼容的储层组成
公开(公告)号：US20070100274A1
公开(公告)日：2007-05-03
申请号：US11556413
申请日：2006-11-03
申请人： Wendy Young , Michel Cormier
发明人： Wendy Young , Michel Cormier
IPC分类号： A61N1/30
CPC分类号： A61N1/30
摘要： A transdermal electrotransport drug delivery device having an anode, a cathode and a source of electrical power electrically connected to the anode and the cathode. At least one of the anode and the cathode includes an electrode and a reservoir comprised of a housing composed of a polymeric material and an aqueous medium in contact with the housing. The aqueous medium includes (i) a drug or an electrolyte salt or a mixture thereof, (ii) propylene glycol, and (iii) an antimicrobial agent in an amount sufficient to inhibit microbial growth in the aqueous medium. The propylene glycol prevents the antimicrobial agent from being adsorbed by other materials used in the construction of the delivery device. A process for preparing a transdermal electrotransport drug delivery device is also provided.
摘要翻译：具有电连接到阳极和阴极的阳极，阴极和电源的透皮电运输药物递送装置。阳极和阴极中的至少一个包括电极和由包含聚合物材料的外壳和与外壳接触的水性介质的容器。水性介质包括（i）药物或电解质盐或其混合物，（ii）丙二醇，和（iii）足以抑制水性介质中微生物生长的量的抗微生物剂。丙二醇防止抗微生物剂被用于构建输送装置的其它材料吸附。还提供了一种制备透皮电转运药物递送装置的方法。

5. 发明申请

US20070078096A1 Buffered drug formulations for transdermal electrotransport delivery 审中-公开
标题翻译：用于经皮电转运的缓冲药物制剂
公开(公告)号：US20070078096A1
公开(公告)日：2007-04-05
申请号：US11356339
申请日：2006-02-16
申请人： Michel Cormier , Sara Sendelbeck , Anna Muchnik , Iris Leung
发明人： Michel Cormier , Sara Sendelbeck , Anna Muchnik , Iris Leung
IPC分类号： A61K38/04 , A61N1/30
CPC分类号： A61K38/27 , A61K9/0009 , A61K9/0014 , A61K38/28 , A61K47/183 , A61K47/38 , A61N1/0424 , A61N1/044 , A61N1/0444 , A61N1/30 , A61N1/327
摘要： Buffered drug formulations for transdermal electrotransport delivery are disclosed. The formulations utilize a dipeptide as a buffer and allow for more efficient electrotransport delivery of drugs, e.g., polypeptide drugs, via the transdermal route.
摘要翻译：公开了用于透皮电转运递的缓冲药物制剂。制剂利用二肽作为缓冲液，并允许通过经皮途径更有效地电转运药物，例如多肽药物。

6. 发明申请

US20060182789A1 Apparatus and method for transdermal delivery of epoetin-based agents 审中-公开
标题翻译：用于透皮递送基于epoetin的药剂的装置和方法
公开(公告)号：US20060182789A1
公开(公告)日：2006-08-17
申请号：US11355856
申请日：2006-02-15
申请人： Mahmoud Ameri , Michel Cormier , Yuh-Fun Maa , Peter Daddona
发明人： Mahmoud Ameri , Michel Cormier , Yuh-Fun Maa , Peter Daddona
IPC分类号： A61K38/18 , A61F13/02 , A61M31/00
CPC分类号： A61M37/0015 , A61K9/0021 , A61K9/06 , A61K38/1816 , A61M2037/0023 , A61M2037/0046
摘要： An apparatus and method for transdermally delivering a biologically active agent comprising a delivery system having a microprojection member (or system) that includes a plurality of microprojections (or array thereof) that are adapted to pierce through the stratum corneum into the underlying epidermis layer, or epidermis and dermis layers. In one embodiment, an Epoetin-based agent is contained in a biocompatible coating that is applied to the microprojection member. In a further embodiment, the delivery system includes a gel pack having an Epoetin-based agent-containing hydrogel formulation that is disposed on the microprojection member after application to the skin of a patient. In an alternative embodiment, the Epoetin-based agent is contained in both the coating and the hydrogel formulation.
摘要翻译：一种用于透皮递送生物活性剂的装置和方法，包括具有微突出物构件（或系统）的递送系统，所述微突出物构件（或系统）包括多个微突出物（或阵列），所述微突出物构件（或阵列）适于穿透角质层穿入下面的表皮层，或表皮和真皮层。在一个实施方案中，基于Epoetin的试剂包含在施加到微喷射构件的生物相容性涂层中。在另一个实施方案中，递送系统包括具有基于Epoetin的含药剂的水凝胶制剂的凝胶包，其在施用到患者皮肤之后设置在微突出物构件上。在替代实施方案中，基于Epoetin的试剂包含在涂层和水凝胶制剂中。

7. 发明申请

US20050090009A1 Compositions of stabilized DNA for coating microprojctions 审中-公开
标题翻译：用于涂覆微孔的稳定化DNA的组成
公开(公告)号：US20050090009A1
公开(公告)日：2005-04-28
申请号：US10972230
申请日：2004-10-21
申请人： Michel Cormier , Georg Widera , Mahmoud Ameri
发明人： Michel Cormier , Georg Widera , Mahmoud Ameri
IPC分类号： A61K48/00 , C12N15/89 , C12N15/87
CPC分类号： A61K48/0008 , A61K48/0025 , A61K48/0041 , C12N15/89
摘要： The present invention provides methods and compositions for stabilizing dried nucleic acids with carbohydrates such as non-reducing sugars, polysaccharides, and reducing sugars. Preferably, the stabilized nucleic acids are coated on a microprojection member for transdermal delivery. The invention further provides compositions and methods that involve the use of DNase inhibitors to stabilize dried nucleic acids delivered directly into bodily tissues.
摘要翻译：本发明提供了用碳水化合物如非还原糖，多糖和还原糖稳定干燥的核酸的方法和组合物。优选地，将稳定的核酸涂覆在用于透皮递送的微突出物构件上。本发明还提供涉及使用DNase抑制剂稳定直接递送到身体组织中的干燥核酸的组合物和方法。

8. 发明授权

US5736580A Composition, device, and method for electrotransport agent delivery 失效
公开(公告)号：US5736580A
公开(公告)日：1998-04-07
申请号：US338924
申请日：1994-11-14
申请人： James A. Huntington , Michel Cormier
发明人： James A. Huntington , Michel Cormier
IPC分类号： A61K9/00 , A61K47/10 , A61N1/30 , A61K31/08
CPC分类号： A61K47/10 , A61K9/0009 , A61N1/30
摘要： An electrotransport drug-containing composition is provided. The composition includes a drug to be delivered through a body surface (eg, skin) of a patient, and a permeation enhancer which is solid or semisolid at temperatures typically encountered during storage of pharmaceuticals (eg, temperatures up to at least about 25.degree. C.). The composition of the invention may be applied from a device 10 suitable for electrotransport delivery. A method for increasing electrotransport agent delivery rate and reducing body surface resistance relies on applying the composition of the invention to the body surface, and applying an electric current through the composition and the body surface.

9. 发明授权

US5451407A Reduction or prevention of skin irritation or sensitization during transdermal administration of a irritating or sensitizing drug 失效
标题翻译：在透皮给药刺激性或致敏性药物时减少或预防皮肤刺激或致敏
公开(公告)号：US5451407A
公开(公告)日：1995-09-19
申请号：US63176
申请日：1993-06-21
申请人： Michel Cormier , Alfred Amkraut , Philip W. Ledger
发明人： Michel Cormier , Alfred Amkraut , Philip W. Ledger
IPC分类号： A61K9/70 , A61K47/22 , A61F13/00
CPC分类号： A61K47/22 , A61K9/0014 , A61K9/7023
摘要： The present invention is directed to the transdermal administration of methyl nicotinate and an irritating or sensitizing drug. The invention includes a transdermal drug delivery device comprising a matrix adapted to be placed in irritating/sensitizing drug- and methyl nicotinate-transmitting relation with the skin site. The matrix contains sufficient amounts of irritating/sensitizing drug and of methyl nicotinate, in combination, to continuously administer to the skin for a predetermined period of time the drug to provide an effective therapeutic result. The invention is also directed to a method for either 1) preventing or reducing the irritation caused by an irritating drug or 2) preventing or reducing sensitization from occurring, as well as reducing or eliminating pain and discomfort occurring during the elicitation phase after sensitization has already been induced.
摘要翻译：本发明涉及透明给药烟酸甲酯和刺激性或致敏药物。本发明包括透皮药物递送装置，其包含适于与皮肤部位置于刺激/敏化药物和甲基烟酸酯传递关系中的基质。基质含有足量的刺激性/致敏药物和烟酸甲酯组合，以持续给予皮肤预定的时间以提供有效的治疗结果。本发明还涉及以下方法：1）预防或减少由刺激性药物引起的刺激或2）预防或减少致敏发生，以及减轻或消除致敏期间在引发阶段中发生的疼痛和不适被诱导。

10. 发明授权

US08221353B2 Intravitreal injection device and system 有权
标题翻译：玻璃体内注射装置和系统
公开(公告)号：US08221353B2
公开(公告)日：2012-07-17
申请号：US12456439
申请日：2009-06-16
申请人： Michel Cormier , Gholam Peyman , Kamran Hosseini
发明人： Michel Cormier , Gholam Peyman , Kamran Hosseini
IPC分类号： A61M5/00
CPC分类号： A61F9/0017 , A61M5/24 , A61M5/46 , A61M2005/2407 , A61M2005/2488
摘要： An intravitreal injection system for administering a pharmacological agent formulation to an intravitreal compartment of an eye, comprising (i) an injection member coupled to, or comprising, an internal formulation chamber that is adapted to receive and contain the pharmacological agent formulation therein, (ii) a needle having a first end that is in communication with a formulation chamber and a second injection end, and (iii) a movable platform for positioning the system on the eye, guiding the needle, and limiting the penetration depth of the needle into the eye.
摘要翻译：一种玻璃体内注射系统，用于向眼睛的玻璃体腔内施用药物制剂，其包含（i）与适于在其中接受和容纳其药理学制剂的内部制剂室耦合或包含的注射构件（ii））具有与制剂室和第二注射端连通的第一端的针，以及（iii）用于将系统定位在眼睛上的引导针，并且将针的穿入深度限制到眼。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式