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1. 发明申请

US20060167527A1 Apparatus and method for repair of spinal cord injury 审中-公开
标题翻译：脊髓损伤修复装置及方法
公开(公告)号：US20060167527A1
公开(公告)日：2006-07-27
申请号：US11301735
申请日：2005-12-12
申请人： Philip Femano , Michael Zanakis
发明人： Philip Femano , Michael Zanakis
IPC分类号： A61N1/18
CPC分类号： A61N1/326 , A61N1/205
摘要： An apparatus for stimulating regeneration and repair of damaged spinal nerves, comprising at least two electrodes placed intravertebrally near the site of spinal neurite injury and delivering direct current thereto. A method for stimulating regeneration and repair of damaged spinal nervous tissue, comprising placing electrodes intravertebrally near the site of spinal cord injury and applying direct current at a level sufficient to induce regeneration and repair of damaged spinal neurites but less than the current level at which tissue toxicity occurs.
摘要翻译：一种用于刺激受损的脊髓神经的再生和修复的装置，包括至少两个放置在椎间孔附近的脊柱神经突损伤部位并将直流输送到其上的电极。一种用于刺激受损的脊髓神经组织的再生和修复的方法，包括将脊髓内的电极放置在脊髓损伤部位附近，并以足以引起受损的脊髓神经突的再生和修复的水平施加直流电流，但小于组织的当前水平发生毒性。

2. 发明授权

US5627327A Dynamic system for determining human physical instability 失效
标题翻译：用于确定人体不稳定性的动态系统
公开(公告)号：US5627327A
公开(公告)日：1997-05-06
申请号：US685951
申请日：1996-07-22
申请人： Michael Zanakis
发明人： Michael Zanakis
IPC分类号： A61B5/103 , A63B22/18 , A63B24/00 , A63B26/00 , A61B5/00
CPC分类号： A63B21/0004 , A61B5/1036 , A61B5/4023 , A63B22/18 , A63B26/003 , A63B2022/0033 , A63B2071/0641
摘要： A dynamic system adapted to test a patient to determine the degree to which his physical stability is impaired and therefore predisposes the patient to injurious falls. The system includes a stable platform yielding signals that depend on the magnitude and direction of the force applied to the face of the platform. The platform is rendered unsteady by a convex rocker dish resting on the the platform face and having a flat top on which the patient stands. The resultant signals which are a function of the changing orientation of the flat top of the dish relative to the platform face are fed to a computer whose output is applied to a video monitor having a display screen on which is presented a cursor whose position is controlled by the signals. The standing patient, while viewing the screen, is required to so shift his weight on the rocker dish as to alter the orientation of the flat top to produce signals causing the cursor to travel from the center of the screen toward a computer-generated target presented on one corner of the screen, and to then acquire the target. The computer measures and scores the time it takes for the patient to cause the cursor to acquire the target as well as other variables that reflect the relative instability of the patient. These scores, taken together, define a stability index useful in deciding how then to treat the patient to improve his condition.
摘要翻译：一种动态系统，其适于测试患者以确定其物理稳定性受损的程度，并因此使患者易受伤害。该系统包括稳定的平台，产生取决于施加到平台的面上的力的大小和方向的信号。平台由搁置在平台表面上的凸起的摇摆盘变得不稳定，并且具有患者站立的平坦顶部。作为盘的平坦顶部相对于平台面的方位改变的函数的结果信号被馈送到计算机，其输出被施加到具有显示屏幕的视频监视器，在显示屏上呈现其位置被控制的光标通过信号。站立的病人在观看屏幕的同时，需要在摇杆上移动自己的重量，以便改变平顶的方位，以产生信号，导致光标从屏幕中心向计算机生成的目标传播在屏幕的一个角落，然后获取目标。计算机测量和评分患者使光标获取目标所需的时间以及反映患者相对不稳定性的其他变量。这些得分一起确定了一个稳定性指标，有助于决定如何治疗病人改善病情。

3. 发明授权

US06981980B2 Self-inflating intragastric volume-occupying device 有权
标题翻译：自充气胃内体积占用装置
公开(公告)号：US06981980B2
公开(公告)日：2006-01-03
申请号：US10390902
申请日：2003-03-19
申请人： Douglas C. Sampson , Michael Zanakis
发明人： Douglas C. Sampson , Michael Zanakis
IPC分类号： A61M29/02
CPC分类号： A61F5/003 , A61F5/0036 , A61M25/10 , A61M29/02 , A61M2205/8225 , A61M2210/1053
摘要： A self-inflating, intragastric balloon device is activated by addition of an activating liquid into an acid or water soluble vessel located within the balloon. After an approximately pre-determined time period post-activation, the activating liquid breaches the vessel wall and causes contact between an acid in liquid form and an emissive substance within the balloon, causing it to inflate. The device is conveniently provided to medical personnel as part of a kit that further contains a syringe and the activating liquid. The device also can have acid or pepsin degradable portions that cause it to deflate after residing in the stomach for a prolonged period of time during which it imparts a feeling of satiety in the patient.
摘要翻译：通过将活化液体添加到位于气囊内的酸性或水溶性容器中来激活自充气的胃内气囊装置。在激活后大致预定的时间段之后，活化液体破坏血管壁并引起液体形式的酸与球囊内的发射物质之间的接触，导致其膨胀。该装置方便地提供给医疗人员作为进一步包含注射器和活化液体的试剂盒的一部分。该装置还可以具有酸或胃蛋白酶可降解部分，使其在居住在胃中长时间放气以在患者体内产生饱腹感的部位使其放气。

4. 发明授权

US5830158A Dynamic system for determining human physical instability 失效
标题翻译：用于确定人体不稳定性的动态系统
公开(公告)号：US5830158A
公开(公告)日：1998-11-03
申请号：US761653
申请日：1996-12-06
申请人： Michael Zanakis
发明人： Michael Zanakis
IPC分类号： A61B5/103 , A63B22/18 , A63B24/00 , A63B26/00
CPC分类号： A63B21/0004 , A61B5/1036 , A61B5/4023 , A63B22/18 , A63B26/003 , A63B2022/0033 , A63B2071/0641
摘要： A dynamic system adapted to test a patient to determine the degree to which his physical stability is impaired and therefore predisposes the patient to injurious falls. The system includes an unsteady platform supported at a raised position above ground and free to rock about a horizontal X-axis and about a Y-axis which intersects the X axis at the center of the platform and is normal thereto so that the orientation of the platform is changeable relative to these axes. Mounted on the platform are electronic clinometers that yield signals which are a function of the deviation of the platform from the horizontal X and Y axes and therefore depend on the changing orientation of the platform when a patient to be tested stands thereon. These signals are fed to a computer whose output is applied to a video monitor having a display screen on which is presented a cursor the position of which is controlled by the signals. The standing patient, while viewing the screen, is required to so shift his weight on the platform as to alter its orientation to produce signals causing the cursor to travel from the center of the screen toward a computer-generated target presented on one corner of the screen, and to then acquire the target. The computer measures and scores the time it takes for the patient to cause the cursor to acquire the target as well as other variables that reflect the relative instability of the patient. These scores, taken together, define a stability index useful in deciding how then to treat the patient to improve his condition.
摘要翻译：一种动态系统，其适于测试患者以确定其物理稳定性受损的程度，并因此使患者易受伤害。该系统包括一个不平稳的平台，它支撑在地面上方的升高位置，并且在平台的中心处绕水平的X轴和与X轴相交的Y轴自由摇摆，并且与Y轴正交，从而使得平台相对于这些轴是可变的。安装在平台上的是电子测量仪，其产生信号，该信号是平台与水平X和Y轴的偏差的函数，因此取决于待测试患者站在其上时平台的改变方向。这些信号被馈送到计算机，该计算机的输出被施加到具有显示屏幕的视频监视器，在显示屏上显示其位置由信号控制的光标。站立的病人在观看屏幕的同时，需要在平台上移动自己的重量，以改变其方位，以产生信号，导致光标从屏幕中心行进到呈现在屏幕的一个角落上的计算机生成的目标屏幕，然后获取目标。计算机测量和评分患者使光标获取目标所需的时间以及反映患者相对不稳定性的其他变量。这些得分一起确定了一个稳定性指标，有助于决定如何治疗病人改善病情。

5. 发明申请

US20060058829A1 Intragastric volume-occupying device 审中-公开
标题翻译：内置体积占用装置
公开(公告)号：US20060058829A1
公开(公告)日：2006-03-16
申请号：US11203108
申请日：2005-08-15
申请人： Douglas Sampson , Michael Zanakis
发明人： Douglas Sampson , Michael Zanakis
IPC分类号： A61M29/00
CPC分类号： A61F5/003 , A61F5/0036
摘要： A self-inflating and self-deflating orally ingestible device that is able to traverse the entirety of the alimentary canal is described. In one embodiment, the device includes a closed balloon having a surface separating an enclosed space internal to the balloon from a space external to the balloon, at least one self-sealing valve integrated with the surface of the balloon to provide access to the enclosed space internal to the balloon from the space external to the balloon, a vent comprised of a dissolvable seal integrated with the surface of the balloon, and a vessel located within the enclosed space internal to the balloon to separate internal contents of the vessel from the enclosed space internal to the balloon.
摘要翻译：描述了能够穿过整个消化道的自充气和自放气的口服摄取装置。在一个实施例中，该装置包括封闭的气囊，其具有将球囊内部的封闭空间与球囊外部空间分开的表面，至少一个与气囊表面整合的自密封阀，以提供对封闭空间的通路气球外部从气球外部的空间内部形成的通气口包括与球囊表面集成的可溶解密封件，以及位于气囊内部的封闭空间内的容器，以将容器的内部内容物与封闭空间分离气球内部

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