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1. 发明授权

US06583181B1 Antimicrobial quaternary ammonium compositions with reduced ocular irritation 失效
标题翻译：减少眼睛刺激的抗微生物季铵组合物
公开(公告)号：US06583181B1
公开(公告)日：2003-06-24
申请号：US09721523
申请日：2000-11-22
申请人： Michael Yao-Chi Chiang , Larry Kent Hall
发明人： Michael Yao-Chi Chiang , Larry Kent Hall
IPC分类号： A61K3114
CPC分类号： A61K31/195 , A01N33/12 , A61K9/0048 , A61K31/14 , A61K33/00 , A61K33/02 , A01N37/44 , A01N25/32 , A01N2300/00 , A61K2300/00
摘要： The present inventors have discovered that electrolytes, such as the tetrasodium salt of ethylenediaminetetraacetic acid (EDTA), reduce the ocular irritation and increase the disinfecting and sanitizing efficacy of compositions containing quaternary ammonium compounds and/or amines. As a result, concentrated solutions containing quaternary ammonium compounds and/or amines of the present invention have low, if any, ocular irritation. Furthermore, use dilutions of the concentrated solutions of the present invention include ingredients which are approved by the U.S. EPA for use on indirect food contact surfaces, unlike disinfecting and sanitizing compositions containing imidazoline compounds. Additionally, the use dilutions exhibit superior efficacy against gram negative and positive bacteria compared to similar compositions which do not contain the electrolyte and remain effective in hard water. The present invention is a concentrate, such as a sanitizing and disinfecting concentrate, comprising from about 0.5 to about 4.0% by weight of a quaternary ammonium compound, an amine, or a combination thereof and from about 2.0 to about 15.0% by weight of electrolyte, based upon 100% total weight of concentrate. The concentrate is generally substantially free of imidazoline compounds. Another embodiment is an ophthalmic solution comprising a quaternary ammonium compound, an amine, or a combination thereof, at least one electrolyte, and, optionally, a biologically active agent.
摘要翻译：本发明人已经发现，电解质，例如乙二胺四乙酸（EDTA）的四钠盐，减少眼睛刺激，并增加含有季铵化合物和/或胺的组合物的消毒和消毒功效。结果，含有本发明的季铵化合物和/或胺的浓缩溶液具有低的眼睛刺激性（如果有的话）。此外，使用本发明的浓缩溶液的稀释液包括美国EPA批准用于间接食品接触表面的成分，不同于消毒和消毒含有咪唑啉化合物的组合物。此外，与不含电解质并在硬水中有效的类似组合物相比，使用稀释物对革兰氏阴性细菌和阳性细菌表现出优异的功效。本发明是一种浓缩物，例如消毒和消毒浓缩物，其包含约0.5至约4.0重量％的季铵化合物，胺或其组合和约2.0至约15.0重量％的电解质，基于浓缩物的总重量的100％。浓缩物通常基本上不含咪唑啉化合物。另一个实施方案是包含季铵化合物，胺或其组合，至少一种电解质和任选的生物活性剂的眼用溶液。

2. 发明授权

US6117831A Alkali metal salts of hydroxyalkyl sulfonates of aminoalkyl alkanol amines and aminoalkyl alkanol ethers and method of making same 有权
标题翻译：氨基烷基烷醇胺和氨基烷基链烷醇醚的羟烷基磺酸盐的碱金属盐及其制备方法
公开(公告)号：US6117831A
公开(公告)日：2000-09-12
申请号：US146880
申请日：1998-09-03
申请人： Michael Yao-Chi Chiang , Daniel Wayne Lemke , Joseph William Scheblein
发明人： Michael Yao-Chi Chiang , Daniel Wayne Lemke , Joseph William Scheblein
IPC分类号： C11D1/18 , C11D3/02 , C11D3/34 , C11D1/75
CPC分类号： C11D3/044 , C11D1/18 , C11D3/349
摘要： The subject invention relates to a novel class of compounds, known as alkali metal salts of hydroxyalkyl sulfonates of aminoalkyl alkanol amines and/or aminoalkyl alkanol ethers, the methods of making such compounds, the alkali-stable solutions containing such compounds, and the use of said solutions as strong detergent compositions. Those alkali-stable solutions are temperature-stable, exhibit superior wetting characteristics, and can be made into low or high foam formulations useful for hard surface cleaning, oven and grill cleaning, metal cleaning, bottle washing, steam cleaning and wax stripping formulations.
摘要翻译：本发明涉及一类新的化合物，称为氨基烷基烷醇胺和/或氨基烷基链烷醇醚的羟烷基磺酸盐的碱金属盐，制备这些化合物的方法，含有这些化合物的碱稳定溶液，以及使用所述溶液作为强洗涤剂组合物。这些碱稳定的溶液是温度稳定的，表现出优异的润湿特性，并且可以制成用于硬表面清洁，烤箱和烤架清洁，金属清洁，洗瓶，蒸汽清洁和蜡剥离制剂的低或高泡沫配方。

3. 发明授权

US5981461A Cleaning compositions containing a halogen bleaching agent and a sulfosuccinate salt 失效
标题翻译：含有卤素漂白剂和磺基琥珀酸盐的清洁组合物
公开(公告)号：US5981461A
公开(公告)日：1999-11-09
申请号：US188502
申请日：1998-11-09
申请人： Michael Wayne Counts , Michael Yao-Chi Chiang
发明人： Michael Wayne Counts , Michael Yao-Chi Chiang
IPC分类号： C11D1/12 , C11D3/34 , C11D3/395 , C11D3/00 , C09K3/22 , C11D7/28 , C11D7/54
CPC分类号： C11D3/3955 , C11D1/123 , C11D3/3472
摘要： The present invention relates to cleaning compositions containing one or more halogen bleaching agents and a sulfosuccinate salt. It has been unexpectedly found in accordance with the present invention that the addition of a sulfosuccinate salt to a halogen bleaching agent significantly enhances the cleaning capacity of the halogen bleaching agent compared to the cleaning capacity of either compound alone. The present invention further relates to a method of treating a contaminated surface by washing the contaminated surface with a cleaning composition containing one or more halogen bleaching agents and sulfosuccinate salts. A method of removing soil or oily substances from a substrate by treating the substrate with a cleaning composition containing one or more halogen bleaching agents and sulfosuccinate salts is also provided by this invention.
摘要翻译：本发明涉及含有一种或多种卤素漂白剂和磺基琥珀酸盐的洗涤组合物。根据本发明意外地发现，与卤素漂白剂中的磺基琥珀酸盐相比，与单独的任一化合物的清洗能力相比，增加了卤素漂白剂的清洗能力。本发明还涉及通过用含有一种或多种卤素漂白剂和磺基琥珀酸盐的清洁组合物洗涤污染表面来处理污染表面的方法。本发明还提供了一种通过用含有一种或多种卤素漂白剂和磺基琥珀酸盐的清洁组合物处理基材从基材中除去土壤或油性物质的方法。

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