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1. 发明申请

US20100074957A1 INTRAOCULAR FORMULATION 审中-公开
标题翻译：内分泌制剂
公开(公告)号：US20100074957A1
公开(公告)日：2010-03-25
申请号：US12626408
申请日：2009-11-25
申请人： MICHAEL R. ROBINSON , Wendy M. Blanda , Hui Liu , Scott M. Whitcup , Patrick M. Hughes
发明人： MICHAEL R. ROBINSON , Wendy M. Blanda , Hui Liu , Scott M. Whitcup , Patrick M. Hughes
IPC分类号： A61K9/14 , A61K9/50 , A61K31/573 , A61P27/02
CPC分类号： A61K9/1647 , A61K9/0048 , A61K31/573 , A61K47/36 , C07K16/22 , C07K2317/76
摘要： Biodegradable therapeutic agent incorporating microspheres formulated in a high viscosity carrier suitable for intraocular administration to treat an ocular condition. The formulation can also be used to treat non-ocular conditions such as articular pathologies.
摘要翻译：配制在适用于眼内给药的高粘度载体中的微球的可生物降解治疗剂用于治疗眼部病症。该制剂也可用于治疗非眼部疾病如关节病变。

2. 发明申请

US20090148527A1 INTRAOCULAR FORMULATION 审中-公开
标题翻译：内分泌制剂
公开(公告)号：US20090148527A1
公开(公告)日：2009-06-11
申请号：US11952938
申请日：2007-12-07
申请人： Michael R. Robinson , Wendy M. Blanda , Hui Liu , Scott M. Whitcup , Patrick M. Hughes
发明人： Michael R. Robinson , Wendy M. Blanda , Hui Liu , Scott M. Whitcup , Patrick M. Hughes
IPC分类号： A61K9/00 , A61K9/14 , A61P27/02
CPC分类号： A61K9/1647 , A61K9/0048 , A61K31/573 , A61K47/36 , C07K16/22 , C07K2317/76
摘要： Biodegradable therapeutic agent incorporating microspheres formulated in a high viscosity carrier suitable for intraocular administration to treat an ocular condition. The formulation can also be used to treat non-ocular conditions such as articular pathologies.
摘要翻译：配制在适用于眼内给药的高粘度载体中的微球的可生物降解治疗剂用于治疗眼部病症。该制剂也可用于治疗非眼部疾病如关节病变。

3. 发明申请

US20130017268A1 PROSTAGLANDIN AND PROSTAMIDE DRUG DELIVERY SYSTEMS AND INTRAOCULAR THERAPEUTIC USES THEREOF 有权
标题翻译： PROSTAGLANDIN和PROSTAMIDE药物输送系统及其内科治疗用途
公开(公告)号：US20130017268A1
公开(公告)日：2013-01-17
申请号：US13596904
申请日：2012-08-28
申请人： Michael R. Robinson , Hui Liu , Patrick M. Hughes , Lon T. Spada , Alazar N. Ghebremeskel
发明人： Michael R. Robinson , Hui Liu , Patrick M. Hughes , Lon T. Spada , Alazar N. Ghebremeskel
IPC分类号： A61K9/14 , A61P27/06 , A61K31/216
CPC分类号： A61L31/06 , A61K9/0048 , A61K9/0051 , A61K9/1647 , A61K9/204 , A61K31/216 , A61K31/557 , A61K31/5575 , A61L31/16
摘要： Biocompatible, bioerodible implants and microspheres include latanoprost and a biodegradable polymer effective, when placed intraocular (such as into the subtenon space) to treat glaucoma.
摘要翻译：生物相容性，生物可侵蚀的植入物和微球体包括拉坦前列素和可生物降解的聚合物，当放置眼内（如进入subtenon空间）治疗青光眼时有效。

4. 发明授权

US08771745B2 Prostaglandin and prostamide drug delivery systems and intraocular therapeutic uses thereof 有权
标题翻译：前列腺素和前列腺酰胺药物递送系统及其眼内治疗用途
公开(公告)号：US08771745B2
公开(公告)日：2014-07-08
申请号：US13596904
申请日：2012-08-28
申请人： Michael R. Robinson , Hui Liu , Patrick M. Hughes , Lon T. Spada , Alazar N. Ghebremeskel
发明人： Michael R. Robinson , Hui Liu , Patrick M. Hughes , Lon T. Spada , Alazar N. Ghebremeskel
IPC分类号： A61K9/14 , A61K9/00
CPC分类号： A61L31/06 , A61K9/0048 , A61K9/0051 , A61K9/1647 , A61K9/204 , A61K31/216 , A61K31/557 , A61K31/5575 , A61L31/16
摘要： Biocompatible, bioerodible implants and microspheres include latanoprost and a biodegradable polymer effective, when placed intraocular (such as into the subtenon space) to treat glaucoma.
摘要翻译：生物相容性，生物可侵蚀的植入物和微球体包括拉坦前列素和可生物降解的聚合物，当放置眼内（如进入subtenon空间）治疗青光眼时有效。

5. 发明申请

US20130017243A1 SUSTAINED-RELEASE RESERVOIR IMPLANTS FOR INTRACAMERAL DRUG DELIVERY 审中-公开
公开(公告)号：US20130017243A1
公开(公告)日：2013-01-17
申请号：US13583183
申请日：2011-04-05
申请人： Ruiwen Shi , Patrick M. Hughes , James A. Burke , Michael R. Robinson , Hui Liu
发明人： Ruiwen Shi , Patrick M. Hughes , James A. Burke , Michael R. Robinson , Hui Liu
IPC分类号： A61K9/00 , A61P27/02 , A61K31/4025 , A61F9/00
CPC分类号： A61K9/0051 , A61K9/0092 , A61K31/382 , A61K31/4025 , A61K31/498 , A61K31/5377 , A61K31/5575 , A61K31/5578
摘要： The present invention provides a sustained release implant for intraocular use to treat elevated intraocular pressure, which implant is configured for intracameral or anterior vitreal administration to a patient with elevated intraocular pressure (IOP), said implant comprising a core of an antihypertensive agent surrounded by a polymer, which limits the rate of passage of the antihypertensive agent from the implant into the eye of said patient and said implant provides a linear rate of release of therapeutically effective amounts of said anti-hypertensive agent into the eye for a period of time of between 14 days and 365 days.

6. 发明申请

US20100247606A1 INTRAOCULAR SUSTAINED RELEASE DRUG DELIVERY SYSTEMS AND METHODS FOR TREATING OCULAR CONDITIONS 审中-公开
标题翻译：内镜持续释放药物输送系统及治疗眼睛病症的方法
公开(公告)号：US20100247606A1
公开(公告)日：2010-09-30
申请号：US12411250
申请日：2009-03-25
申请人： Michael R. ROBINSON , James A. Burke , Hui Liu , Werhner C. Orilla , Lon T. Spada , Scott Whitcup , Alazar N. Ghebremskel , Patrick M. Hughes , Kun Xu , Marianne M. Do
发明人： Michael R. ROBINSON , James A. Burke , Hui Liu , Werhner C. Orilla , Lon T. Spada , Scott Whitcup , Alazar N. Ghebremskel , Patrick M. Hughes , Kun Xu , Marianne M. Do
IPC分类号： A61F2/00 , A61K31/215 , A61K31/165 , A61K9/14 , A61K31/4025 , A61K31/426 , A61K31/415 , A61K31/42
CPC分类号： A61K31/557 , A61K9/0051 , A61K9/1647 , A61K9/70 , A61K31/00 , A61K31/5575
摘要： Biocompatible, bioerodible sustained release implants and microspheres for intracameral or anterior vitreal placement include an anti-hypertensive agent and a biodegradable polymer effective to treat an ocular hypertensive condition (such as glaucoma) by relapsing therapeutic amount of the anti-hypertensive agent over a period of time between 10 days and 1 year.
摘要翻译：生物相容性，生物可蚀性缓释植入物和用于乳房内或玻璃体前置放置的微球包括抗高血压剂和可生物降解的聚合物，其通过在一段时间内复发治疗量的抗高血压药物而有效治疗眼高血压病症（如青光眼）时间在10天到1年之间。

7. 发明申请

US20100104654A1 PROSTAGLANDIN AND PROSTAMIDE DRUG DELIVERY SYSTEMS AND INTRAOCULAR THERAPEUTIC USES THEREOF 审中-公开
标题翻译： PROSTAGLANDIN和PROSTAMIDE药物输送系统及其内科治疗用途
公开(公告)号：US20100104654A1
公开(公告)日：2010-04-29
申请号：US12259153
申请日：2008-10-27
申请人： Michael R. Robinson , Hui Liu , Patrick M. Hughes , Lon T. Spada , Alazar N. Ghebremeskel
发明人： Michael R. Robinson , Hui Liu , Patrick M. Hughes , Lon T. Spada , Alazar N. Ghebremeskel
IPC分类号： A61K9/14 , A61K31/216
CPC分类号： A61L31/06 , A61K9/0048 , A61K9/0051 , A61K9/1647 , A61K9/204 , A61K31/216 , A61K31/557 , A61K31/5575 , A61L31/16
摘要： Biocompatible, bioerodible implants and microspheres include latanoprost and a biodegradable polymer effective, when placed intraocular (such as into the subtenon space) to treat glaucoma.
摘要翻译：生物相容性，生物可侵蚀的植入物和微球体包括拉坦前列素和可生物降解的聚合物，当放置眼内（如进入subtenon空间）治疗青光眼时有效。

8. 外观设计

USD1008739S1 Double wall beverage container 有权
公开(公告)号：USD1008739S1
公开(公告)日：2023-12-26
申请号：US29775552
申请日：2021-03-24
申请人： Umair Khan , Hajra Khan , Hui Liu
设计人： Umair Khan , Hajra Khan , Hui Liu
摘要： FIG. 1 is a perspective view of the double wall beverage container.
FIG. 2 is a front elevational view of the double wall beverage container.
FIG. 3 is a rear elevational view thereof.
FIG. 4 is a top plan view thereof.
FIG. 5 is a bottom plan view thereof.
FIG. 6 is a left side elevational view thereof; and,
FIG. 7 is a right side elevational view thereof.
The broken lines showing of the handle in FIGS. 1, 2, 3, 4, 5 and 7 form no part of the claimed design.

9. 发明授权

US09191163B2 Systems and methods for hybrid content delivery 有权
标题翻译：混合内容传送的系统和方法
公开(公告)号：US09191163B2
公开(公告)日：2015-11-17
申请号：US13411057
申请日：2012-03-02
申请人： Hui Liu
发明人： Hui Liu
IPC分类号： H04B7/00 , H04L1/18 , H04L1/00
CPC分类号： H04L1/1893 , H04L2001/0093 , H04L2001/0097
摘要： Systems and methods which provide data communication content delivery through a hybrid network implementation are disclosed. A hybrid network configuration may utilize a broadcast communication technique to deliver large amounts of data communication content to one or more mobile communication device via uni-directional network links and a uni-cast communication technique via bi-directional network links with the one or more mobile communication device to facilitate delivery and utilization of the data communication content. Data content delivery loss recovery techniques implemented according to embodiments of the invention utilize network links of the hybrid network other than or in addition to the uni-directional network links to implement loss recovery techniques such as a hybrid repeat technique, a hybrid retransmission technique, hybrid statistical feedback technique, and/or combinations thereof.
摘要翻译：公开了通过混合网络实现提供数据通信内容传送的系统和方法。混合网络配置可以利用广播通信技术，通过单向网络链路和通过与一个或多个移动台的双向网络链路的单播通信技术将大量的数据通信内容传送到一个或多个移动通信设备通信设备，便于数据通信内容的传送和利用。根据本发明的实施例实现的数据内容传送丢失恢复技术利用除了单向网络链路之外的或除了单向网络链路之外的混合网络的网络链路来实现诸如混合重复技术，混合重传技术，混合统计反馈技术，和/或其组合。

10. 发明授权

US09161255B2 Reporting method, detection method, device and system for network state 有权
标题翻译：报告方式，检测方法，网络状态的设备和系统
公开(公告)号：US09161255B2
公开(公告)日：2015-10-13
申请号：US14009638
申请日：2012-03-20
申请人： Tao Xue , Junchao Du , Hui Liu , Qingzhe Deng , Chuanyi Liu , Xuan Li , Weizhen Ji , Xiaojun Li , Wen He , Wenjing Chen , Jiangkun Guo
发明人： Tao Xue , Junchao Du , Hui Liu , Qingzhe Deng , Chuanyi Liu , Xuan Li , Weizhen Ji , Xiaojun Li , Wen He , Wenjing Chen , Jiangkun Guo
IPC分类号： H04W80/04 , H04W88/06 , H04W88/08 , H04W24/10 , H04W24/04
CPC分类号： H04W24/10 , H04W24/04
摘要： A reporting method for a network state includes: an intermediate node receiving a data packet; the intermediate node marking the data packet according to the current network state; and the intermediate node forwarding the marked data packet. A detecting method for a network state includes: a sink node receiving a data packet; the sink node parsing the data packet to obtain the marking information about the network state; and the sink node determining the network state according to the marking information. A reporting device corresponding to the reporting method, a detecting device corresponding to the detecting method, and a detecting system comprising the reporting device and the detecting method are also provided.
摘要翻译：一种网络状态报告方法包括：接收数据分组的中间节点; 中间节点根据当前网络状态标记数据包; 并且中间节点转发标记的数据分组。一种用于网络状态的检测方法包括：接收节点接收数据分组; 汇聚节点解析数据包，获取关于网络状态的标记信息; 并且汇聚节点根据标记信息确定网络状态。还提供了与报告方法对应的报告装置，与检测方法相对应的检测装置，以及包括报告装置和检测方法的检测系统。

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