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1. 发明申请

US20070100204A1 Endoscope reprocessor connectivity apparatus and method 有权
标题翻译：内窥镜再处理器连接装置及方法
公开(公告)号：US20070100204A1
公开(公告)日：2007-05-03
申请号：US11264909
申请日：2005-11-02
申请人： Paul Feld , Michael Petersen , John Marxer , Ward Sly , Johannes Walta
发明人： Paul Feld , Michael Petersen , John Marxer , Ward Sly , Johannes Walta
IPC分类号： A61B1/12 , A61B1/04
CPC分类号： A61L2/18 , A61B1/00057 , A61B1/125 , A61B90/70 , A61B2090/701
摘要： Apparatus and method for detecting connectivity in a channel in an endoscope undergoing reprocessing using an automatic reprocessor, the apparatus including a source of pressurized fluid which may be a gas alone or gas and liquid and a back pressure detector connected to the channel or channels of interest in the endoscope, the method including providing a source of pressurized fluid, directing the pressurized fluid to a channel in an endoscope, monitoring the time for the back pressure in the pressurized fluid to decay to a predetermined level; and determining whether the channel is connected and open or disconnected by comparing the decay time of the actual back pressure to one or more predetermined values corresponding to the specific channel or channels and model of endoscope undergoing reprocessing.
摘要翻译：用于检测使用自动再处理器进行再处理的内窥镜中的通道中的连通性的装置和方法，该装置包括可以是单独的气体或气体和液体的加压流体源和连接到感兴趣的通道的背压检测器在内窥镜中，该方法包括提供加压流体源，将加压流体引导到内窥镜中的通道，监测加压流体中的背压衰减到预定水平的时间; 并且通过将实际背压的衰减时间与对应于经历再处理的内窥镜的特定通道或模型的一个或多个预定值进行比较来确定通道是连接和断开还是断开。

2. 发明申请

US20050196314A1 On board monitor for endoscope reprocessor 有权
标题翻译：内置式再处理器板载显示器
公开(公告)号：US20050196314A1
公开(公告)日：2005-09-08
申请号：US11068575
申请日：2005-02-28
申请人： Michael Petersen , Paul Feld
发明人： Michael Petersen , Paul Feld
IPC分类号： A61B1/12 , A61B19/00 , A61L2/18 , A61L2/24
CPC分类号： A61L2/24 , A61B1/12 , A61B1/123 , A61B90/70 , A61B2090/701 , A61L2/18
摘要： An on board monitor for an endoscope reprocessor for monitoring the performance and order of a predetermined set of critical steps for reprocessing an endoscope. The monitor will only allow the overall system to reach the last step indicating successful completion of the process related to the critical steps representing successful reprocessing of an endoscope after the system successfully completes all of the previous critical steps and in the correct order.
摘要翻译：一种用于内窥镜再处理器的板载监视器，用于监视用于再处理内窥镜的预定关键步骤集合的性能和顺序。监视器将仅允许整个系统达到最后一步，指示在系统成功完成所有以前的关键步骤并按正确顺序完成与表示内窥镜成功重新处理的关键步骤相关的过程的成功完成。

3. 发明申请

US20080000405A1 S-adenosylmethionine Synthetase Expression Elements Identified from Arabidopsis thaliana 审中-公开
标题翻译：拟南芥中鉴定的S-腺苷甲硫氨酸合成酶表达元件
公开(公告)号：US20080000405A1
公开(公告)日：2008-01-03
申请号：US11765562
申请日：2007-06-20
申请人： Wei Wu , Kim Beazley , Jill Deikman , Michael Edgerton , Bei Zhang , Qi Wang , Michael Petersen
发明人： Wei Wu , Kim Beazley , Jill Deikman , Michael Edgerton , Bei Zhang , Qi Wang , Michael Petersen
IPC分类号： A01C11/00 , A01H1/00 , A01H5/00 , C07H21/04 , C07K16/00 , C12N5/04
CPC分类号： C12N15/8216 , A01H5/00 , C12N9/1085 , C12N15/8289 , C12Y205/01006
摘要： The present invention provides non-coding regulatory element polynucleotide molecules isolated from the S-adenosyl methionine synthetase (SAMS3) gene of Arabidopsis thaliana and useful for expressing transgenes in plants. The invention further discloses compositions, polynucleotide constructs, transformed host cells, transgenic plants and seeds containing the Arabidopsis thaliana regulatory polynucleotide sequences, and methods for preparing and using the same.
摘要翻译：本发明提供从拟南芥的S-腺苷甲硫氨酸合成酶（SAMS3）基因中分离的非编码调控元件多核苷酸分子，并且可用于在植物中表达转基因。本发明还公开了组合物，多核苷酸构建体，转化的宿主细胞，转基因植物和含有拟南芥调节多核苷酸序列的种子，以及制备和使用拟南芥调节多核苷酸序列的方法。

4. 发明授权

US07229981B2 Process for the preparation of aminoalcohol derivatives and their further conversion to (1R,4S)-4-(2-amino-6-chloro-5-formamido-4-pyrimidinyl)-amino)-2-cyclopentenyl-1-methanol 失效
标题翻译：制备氨基醇衍生物的方法及其进一步转化为（1R，4S）-4-（2-氨基-6-氯-5-甲酰氨基-4-嘧啶基） - 氨基）-2-环戊烯基-1-甲醇
公开(公告)号：US07229981B2
公开(公告)日：2007-06-12
申请号：US10695930
申请日：2003-10-29
申请人： Walter Brieden , Josef Schröer , Christine Bernegger-Egli , Eva Maria Urban , Michael Petersen , Jean-Paul Roduit , Katja Berchtold , Holger Breitbach
发明人： Walter Brieden , Josef Schröer , Christine Bernegger-Egli , Eva Maria Urban , Michael Petersen , Jean-Paul Roduit , Katja Berchtold , Holger Breitbach
IPC分类号： A01N43/00
CPC分类号： C07C213/00 , C07B2200/07 , C07C213/02 , C07C213/08 , C07C213/10 , C07C215/42 , C07C233/23 , C07C271/24 , C07C2601/10 , C07D473/00 , C07D473/40 , C12P13/001 , C12P13/02 , C12P41/007 , C07C215/26
摘要： The invention relates to a novel process for the preparation of an aminoalcohol of the formula racemically or optically active, starting from 2-azabi-cyclo[2.2.1]hept-5-en-3-one, its further conversion to give the corresponding acyl derivative and its further conversion to (1S,4R)— or (1R,4S)-4-(2-amino-6-chloro-9-H-purine-9-yl)-2-cyclopentenyl-1-methanol of the formulae In the latter synthesis, the aminoalcohol is converted into the corresponding D- or L-tartrate, which is then reacted with N-(2-amino-4,6-dichloropyrimidin-5-yl) formamide of the formula to give (1S, 4R)- or (1R, 4S)-4-[(2-amino-6-chloro-5-formamido-4-pyrimidinyl)amino]-2-cyclopentenyl-1-methanol of the formulae and then cyclized to give the end compounds.
摘要翻译：本发明涉及从2-氮杂环[2.2.1]庚-5-烯-3-酮开始制备外消旋或光学活性的氨基醇的新方法，其进一步转化得到相应的酰基衍生物，并进一步转化为（1S，4R） - 或（1R，4S）-4-（2-氨基-6-氯-9H-嘌呤-9-基）-2-环戊烯基-1-甲醇在后一种合成中，将氨基醇转化成相应的D-或L-酒石酸盐，然后与下式的N-（2-氨基-4,6-二氯嘧啶-5-基）甲酰胺反应，得到（ 1S，4R） - 或（1R，4S）-4 - [（2-氨基-6-氯-5-甲酰氨基-4-嘧啶基）氨基] -2-环戊烯基-1-甲醇，然后环化，得到最终化合物。

5. 发明授权

US07113101B2 Blister package with electronic content monitoring system 有权
标题翻译：吸塑包装与电子内容监控系统
公开(公告)号：US07113101B2
公开(公告)日：2006-09-26
申请号：US10500481
申请日：2002-12-30
申请人： Michael Petersen , Allan Wilson
发明人： Michael Petersen , Allan Wilson
IPC分类号： G08B17/02
CPC分类号： B65D75/327 , A61J1/035 , A61J7/0436 , A61J7/0481 , B65D2203/00 , B65D2203/10
摘要： A replicate can be secured to a blister package intended to contain articles, such as pills, and is used to record the removal of individual articles from the blisters. To remove an article from a blister one will usually press against the blister to push the article through a frangible closure seal, breaking the seal in the process. The replicate includes a backing sheet which carries a plurality of traces alignable with corresponding blisters so that when the article is removed from the blister it will not only break the seal but it will also break the corresponding trace. All of the traces are connected to an integrated circuit which may also be formed or provided on the backing sheet, as is a power source for the integrated circuit. The breaking of the trace is an event that is recorded in the integrated circuit for later accessability. The replicate may be secured to the blister package after the package has been produced by conventional form-fill-seal equipment. The individual traces can be formed into a grid of closely spaced traces so that alignment of the traces with the individual blisters is less critical. The replicates may be formed by printing or other conventional methods on a roll of lidstock. After forming the individual replicates are severed from the roll of lidstock for securement to a blister package.
摘要翻译：复制物可以固定到旨在包含诸如丸剂的物品的泡罩包装，并且用于记录从泡罩中取出各个物品。为了从泡罩中去除物品，通常会压在水泡上，以将物品推入易碎的封闭密封件，从而破坏过程中的密封。复制品包括背衬片，其携带可与相应水泡对准的多个迹线，使得当物品从泡罩移除时，其不仅会破坏密封，而且还会破坏相应的痕迹。所有的迹线都连接到也可以形成或设置在背板上的集成电路，如集成电路的电源一样。迹线的断开是记录在集成电路中的事件，用于以后的可访问性。在通过常规的填充 - 密封设备生产包装之后，复制物可以固定到泡罩包装上。各个迹线可以形成为紧密间隔的迹线的网格，使得迹线与各个水泡的对准不太关键。复制品可以通过印刷或其它常规方法形成在卷筒上。在形成之后，将单个重复物从盖子卷上切下，以固定到泡罩包装。

6. 发明申请

US20060173893A1 System and methods for capturing structure of data models using entity patterns 失效
公开(公告)号：US20060173893A1
公开(公告)日：2006-08-03
申请号：US11045756
申请日：2005-01-28
申请人： Esben Kristoffersen , Lars Hammer , Michael Petersen , Heinrich Clausen , Thomas Hejlsberg
发明人： Esben Kristoffersen , Lars Hammer , Michael Petersen , Heinrich Clausen , Thomas Hejlsberg
IPC分类号： G06F17/00 , G06F7/00
CPC分类号： G06Q30/00 , G06Q10/10 , Y10S707/99944
摘要： A system and method directed to capturing the structure of data models using entity patterns is provided wherein an entity pattern is an abstraction, for example in the MICROSOFT BUSINESS FRAMEWORK®(MBF), that surfaces in the model editor of the framework at the root level and consists of one or more entity roles that together define a structural pattern of a model. The entity pattern may be considered as an über-model, or a model template for a model. Prescriptive rules are added to the design of entities, required properties and relations to other entities (entity roles). Applications of the entity patterns are validated at design time. The runtime framework supports any applied pattern and invokes the pattern specific code. It is a general advantage that the runtime operation is model driven and interprets the model data at runtime. The application and usage of a pattern is part of the model of the application/software program.

7. 发明授权

US06893861B1 Method for producing trifluoro-3(r)-hydroxybutyric acid derivatives 失效
标题翻译：制备三氟-3（r） - 羟基丁酸衍生物的方法
公开(公告)号：US06893861B1
公开(公告)日：2005-05-17
申请号：US09622385
申请日：1999-02-18
申请人： Michael Petersen , Olwen Birch , Sakayu Shimizu , Andreas Kjener , Marie-Luise Hischier , Susanne Thöni
发明人： Michael Petersen , Olwen Birch , Sakayu Shimizu , Andreas Kjener , Marie-Luise Hischier , Susanne Thöni
IPC分类号： C12N15/09 , C12N9/02 , C12N9/04 , C12N15/53 , C12P7/42 , C12P7/62 , C12P11/00 , C12P13/02 , C12R1/19 , C12P7/40
CPC分类号： C12N9/0008 , C12N9/0006 , C12P7/42 , C12P7/62 , C12P11/00 , C12P13/02
摘要： The invention relates to a biotechnological method for producing trifluoro-3(R)-hydroxybutyric acid derivatives of the general formula (I), where R1 represents —OR2, where R2 is hydrogen, C1-10 alkyl, C1-10 alkenyl, C3-8 cy-cloalkyl, aryl, alkoxyalkyl or alkoxyalkoxyalkyl; —NR3R4, where R3 and R4 are the same or different and represent hydrogen, C1-10 alkyl, C1-10 alkenyl, C3-8 cycloalkyl or aryl; or —SR5, where R5 represents hydrogen, C1-10 alkyl, C1-10 alkenyl, aryl or C3-8 cycloalkyl, based on a trifluoroacetoacetic acid derivative of the general formula (II), where R1 has the meaning given above, by means of micro-organisms which are able to reduce a carbonyl function or by means of a cell-free enzyme extract of said micro-organisms.
摘要翻译：本发明涉及一种生产通式（I）的三氟-3（R） - 羟基丁酸衍生物的生物技术方法，其中R 1表示-OR 2，其中 R 2是氢，C 1-10烷基，C 1-10 1-10烯基，C 3-8环芳基，烷氧基烷基或烷氧基烷氧基烷基; 其中R 3和R 4相同或不同并且表示氢，C 3和R 4相同或不同，表示氢，C C 1-10烷基，C 1-10 1-10烯基，C 3-8环烷基或芳基; 或-SR 5，其中R 5表示氢，C 1-10烷基，C 1-10 1-10烯基，芳基或C 3-8环烷基，基于通式（II）的三氟乙酰乙酸衍生物，其中R 1具有上述含义，通过微量 - 能够降低羰基官能团或通过所述微生物的无细胞酶提取物的有机体。

8. 发明授权

US06391591B1 Biotechnological process for preparing N-acetylmannosamine 失效
标题翻译：制备N-乙酰甘露糖胺的生物工艺
公开(公告)号：US06391591B1
公开(公告)日：2002-05-21
申请号：US09624982
申请日：2000-07-25
申请人： Michael Petersen , Klaus Heinzmann
发明人： Michael Petersen , Klaus Heinzmann
IPC分类号： C12P1926
CPC分类号： C12P19/26
摘要： Novel microorganisms, which can be obtained by the following selection method: (a) microorganisms which grow using N-acetylglucosamine as the sole carbon source are cultivated in a customary manner, (b) from the resulting culture, these microorganisms are then selected which are stable and have the property to metabolize N-acetylglucosamine rapidly in the presence of N-Acetylmannosamine. Furthermore, a novel process for preparing NAM starting from a mixture of NAM and NAG.
摘要翻译：可以通过以下选择方法获得的新型微生物：（a）以N-乙酰葡糖胺为唯一碳源生长的微生物以常规方式培养，（b）从得到的培养物中，选择这些微生物具有在N-乙酰甘露糖胺存在下快速代谢N-乙酰氨基葡萄糖的性质。此外，还提供了一种从NAM和NAG混合物制备NAM的新方法。

9. 发明授权

US09101530B2 Disposable content use monitoring package with a removable re-usable electronic circuit board 有权
标题翻译：一次性内容使用监控包与可拆卸的可重复使用的电子电路板
公开(公告)号：US09101530B2
公开(公告)日：2015-08-11
申请号：US13881782
申请日：2011-10-26
申请人： Allan Wilson , Michael Petersen , Dean Brotzel
发明人： Allan Wilson , Michael Petersen , Dean Brotzel
IPC分类号： B65D75/00 , A61J1/03 , B65B11/52 , B65B7/28 , B65B69/00 , A61J7/02 , A61J7/04
CPC分类号： A61J1/035 , A61J7/02 , A61J7/04 , A61J7/0418 , A61J7/0436 , A61J7/0481 , A61J2200/30 , B65B7/28 , B65B11/52 , B65B69/005 , Y10T29/49822
摘要： There is provided a content use monitoring package and method of making the same. The package includes a cover layer followed by a blister card layer. The third layer comprises an electronic sensor monitoring tag connected to a rupturable layer imprinted with a conductive grid. The grid is printed on a non-conductive, non paperboard rupturable substrate and is aligned with associated blisters in the blister card. To ensure precise and reliable electrical continuity between the tag and grid they are connected by a low or zero insertion force flat flex connector which connection is also reversible. The tag includes re-usable electronic circuitry and power source. The fourth and bottom layer is a backing which contains a mechanism to tear open the package and remove the tag by unplugging the flex circuit connector. The tag can then be reused and the battery replaced as required.
摘要翻译：提供了一种内容使用监视包及其制作方法。该包装包括覆盖层，随后是泡罩卡层。第三层包括连接到印有导电栅格的可破裂层的电子传感器监测标签。网格印刷在非导电非纸板可破裂基材上，并与吸塑卡中的相关水泡对齐。为了确保标签和电网之间的精确和可靠的电气连续性，它们通过低或零插入力平面柔性连接器连接，该连接也是可逆的。标签包括可重复使用的电子电路和电源。第四层和底层是背衬，其包含撕开包装并通过拔出柔性电路连接器去除标签的机构。然后可以重新使用标签，并根据需要更换电池。

10. 发明申请

US20150164741A1 DISPOSABLE CONTENT USE MONITORING PACKAGE WITH A REMOVABLE RE-USABLE ELECTRONIC CIRCUIT BOARD 有权
标题翻译：可拆卸内容使用可拆卸的可再生电子电路板使用监控包
公开(公告)号：US20150164741A1
公开(公告)日：2015-06-18
申请号：US13881782
申请日：2011-10-26
申请人： Allan Wilson , Michael Petersen , Dean Brotzel
发明人： Allan Wilson , Michael Petersen , Dean Brotzel
IPC分类号： A61J1/03 , A61J7/04 , B65B69/00 , A61J7/02 , B65B11/52 , B65B7/28
CPC分类号： A61J1/035 , A61J7/02 , A61J7/04 , A61J7/0418 , A61J7/0436 , A61J7/0481 , A61J2200/30 , B65B7/28 , B65B11/52 , B65B69/005 , Y10T29/49822
摘要： There is provided a content use monitoring package and method of making the same. The package includes a cover layer followed by a blister card layer. The third layer comprises an electronic sensor monitoring tag connected to a rupturable layer imprinted with a conductive grid. The grid is printed on a non-conductive, non paperboard rupturable substrate and is aligned with associated blisters in the blister card. To ensure precise and reliable electrical continuity between the tag and grid they are connected by a low or zero insertion force flat flex connector which connection is also reversible. The tag includes re-usable electronic circuitry and power source. The fourth and bottom layer is a backing which contains a mechanism to tear open the package and remove the tag by unplugging the flex circuit connector. The tag can then be reused and the battery replaced as required.
摘要翻译：提供了一种内容使用监视包及其制作方法。该包装包括覆盖层，随后是泡罩卡层。第三层包括连接到印有导电栅格的可破裂层的电子传感器监测标签。网格印刷在非导电非纸板可破裂基材上，并与吸塑卡中的相关水泡对齐。为了确保标签和电网之间的精确和可靠的电气连续性，它们通过低或零插入力平面柔性连接器连接，该连接也是可逆的。标签包括可重复使用的电子电路和电源。第四层和底层是背衬，其包含撕开包装并通过拔出柔性电路连接器去除标签的机构。然后可以重新使用标签，并根据需要更换电池。

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