专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US07947469B2 Modulation of HIV infection 有权
标题翻译：调控艾滋病毒感染
公开(公告)号：US07947469B2
公开(公告)日：2011-05-24
申请号：US10470065
申请日：2002-01-22
申请人： Michael Moore , Mark Isalan , Lindsey Reynolds , Christopher Ullman , John Girdlestone , Christophe Demaison , Yen Choo
发明人： Michael Moore , Mark Isalan , Lindsey Reynolds , Christopher Ullman , John Girdlestone , Christophe Demaison , Yen Choo
IPC分类号： C12P21/04 , C12P21/06 , C12Q1/68 , C12N5/00 , C07H21/04
CPC分类号： C07K14/4703 , A61K38/00
摘要： Disclosed herein are methods and compositions for modulating HIV infection by regulating expression of one or more receptors.
摘要翻译：本文公开了通过调节一种或多种受体的表达来调节HIV感染的方法和组合物。

2. 发明申请

US20080070306A1 Regulated gene expression in plants 有权
标题翻译：调节植物中的基因表达
公开(公告)号：US20080070306A1
公开(公告)日：2008-03-20
申请号：US11900536
申请日：2007-09-12
申请人： Yen Choo , Christopher Ullman , Nam-Hai Chua , Juan Sanchez
发明人： Yen Choo , Christopher Ullman , Nam-Hai Chua , Juan Sanchez
IPC分类号： C12N15/82 , C12N5/04
CPC分类号： C40B40/02 , C07K14/415 , C07K14/4702 , C12N15/1037 , C12N15/63 , C12N15/635 , C12N15/8216 , C12N15/8217 , C12N15/8222 , C12N15/8238
摘要： A method is provided of regulating transcription in a plant cell from a DNA sequence comprising a target DNA operably linked to a coding sequence, which method comprises introducing an engineered zinc finger polypeptide in said plant cell which polypeptide binds to the target DNA and modulates transcription of the coding sequence.
摘要翻译：提供了一种从包含与编码序列可操作地连接的靶DNA的DNA序列调节植物细胞中的转录的方法，该方法包括在所述植物细胞中引入工程化锌指多肽，该多肽与靶DNA结合并调节转录编码序列。

3. 发明申请

US20130109616A1 ANTIMICROBIAL PEPTIDES 审中-公开
标题翻译：抗菌肽
公开(公告)号：US20130109616A1
公开(公告)日：2013-05-02
申请号：US13521457
申请日：2011-01-11
申请人： William Eldridge , Christopher Ullman , Marc Alan Fox , David Okhono Ulaeto , Joanne Elizabeth Thwaite
发明人： William Eldridge , Christopher Ullman , Marc Alan Fox , David Okhono Ulaeto , Joanne Elizabeth Thwaite
IPC分类号： C07K14/435
CPC分类号： C07K14/435 , C12N15/1075
摘要： A method is provided for isolating protease resistant antimicrobial peptides (AMPs) from a peptide display library. A plurality of nucleic acid constructs that encode displayed peptides are expressed, resulting in the formation of a plurality of peptide-nucleic acid complexes, each complex comprising at least one displayed peptide associated with the corresponding nucleic acid construct encoding the displayed peptide. The complexes are exposed to at least one protease, to allow the proteolysis of protease-sensitive peptides, such that resistant peptides remain. The peptide-nucleic acid complexes are further exposed to a membrane composition to allow association of complexes that contain membrane-associating peptides. Complexes that remain unassociated with the membrane are removed; and membrane-associated complexes are recovered. The AMPs so characterised may be resistant to one or more protease enzymes and exhibit antimicrobial activity against one or more microbe.
摘要翻译：提供了用于从肽显示库分离抗蛋白酶抗性肽（AMP）的方法。表达编码显示的肽的多个核酸构建体，导致形成多个肽 - 核酸复合物，每个复合物包含与编码所显示的肽的相应核酸构建体相关联的至少一个显示的肽。将复合物暴露于至少一种蛋白酶，以允许蛋白酶敏感肽的蛋白水解，使得保留抗性肽。肽 - 核酸复合物进一步暴露于膜组合物以允许包含膜缔合肽的复合物缔合。与膜保持不相关的复合物被去除; 并回收膜相关复合物。如此表征的AMP可能对一种或多种蛋白酶具有抗性并且对一种或多种微生物表现出抗微生物活性。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式