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1. 发明申请

US20050004471A1 Prostate visualization device and methods of use 审中-公开
标题翻译：前列腺可视化装置及使用方法
公开(公告)号：US20050004471A1
公开(公告)日：2005-01-06
申请号：US10782377
申请日：2004-02-18
申请人： Michael Hogendijk , Thomas Green , Isidro Gandionco , Ryan Boucher , Yuri Belman
发明人： Michael Hogendijk , Thomas Green , Isidro Gandionco , Ryan Boucher , Yuri Belman
IPC分类号： A61B8/00 , A61B8/08 , A61B8/12 , A61F2/958 , A61N5/10 , A61B8/14 , A61M36/12
CPC分类号： A61B8/0841 , A61B8/0833 , A61B8/12 , A61B8/481 , A61M25/1002 , A61M25/1011 , A61M2210/1085 , A61N5/1001 , A61N5/1014 , A61N2005/1011
摘要： Methods and apparatus are provided for improved administration of brachytherapy in the treatment of prostate disease. More particularly, a prostate visualization device is provided comprising a catheter coupled to at least one deployable member at the distal end of the catheter. The deployable member is preferably manufactured from a shape memory alloy having a petal-shaped configuration suitable for engaging and defining the proximal region of a patient's bladder. The deployable member may comprise tubing filled with air or other radiopaque agents to facilitate ultrasonic imaging of the deployable members near the bladder/prostate junction.
摘要翻译：为治疗前列腺疾病提供近距离放射治疗的方法和装置。更具体地，提供了前列腺可视化装置，其包括在导管的远端处联接到至少一个可展开构件的导管。可展开构件优选地由具有适于接合和限定患者膀胱近端区域的花瓣状构型的形状记忆合金制成。可部署构件可以包括填充有空气或其它不透射线剂的管道，以促进膀胱/前列腺结合附近的可部署构件的超声成像。

2. 发明授权

US5055109A Torque transmitting assembly for intravascular devices 失效
标题翻译：用于血管内装置的扭矩传递装置
公开(公告)号：US5055109A
公开(公告)日：1991-10-08
申请号：US417733
申请日：1989-10-05
申请人： Ross Gould , Isidro Gandionco
发明人： Ross Gould , Isidro Gandionco
IPC分类号： A61M29/02
CPC分类号： A61M25/104
摘要： A torque transmitting assembly for guidewires, steerable fixed wire catheters and the like with a drive mechanism wherein the rotational output is greater than the rotational input. The assembly has a supporting structure with proximal and distal end pieces and a connecting arm or strut extending between and secured to the end pieces. An outer cylindrical shaped housing is rotatably mounted about the connecting arm and between the ends. A ring gear or other torque transmitting element is secured to the interior of the housing. A pinion gear or other torque transmitting element having a smaller diameter than the ring gear is rotatably mounted within support structure and the housing and is adapted to engage the ring gear in a torque transmitting relationship. The proximal end of a guidewire or the guiding element of a steerable catheter is secured to the pinion gear so that rotation thereof by the rotation of the housing causes a much greater the rotation of the attached guidewire or guiding element. Preferably means are provided to restrict the number of rotations which can be imparted to the guidewire or guiding means.
摘要翻译：一种用于导线的转矩传递组件，具有驱动机构的可转向固定导线导管等，其中旋转输出大于旋转输入。组件具有支撑结构，其具有近端部件和远端部件以及在端部件之间延伸并固定到端部件上的连接臂或支柱。外圆柱形壳体围绕连接臂可旋转地安装并且在端部之间。环形齿轮或其它扭矩传递元件固定到壳体的内部。具有比环形齿轮更小的直径的小齿轮或其它扭矩传递元件可旋转地安装在支撑结构和壳体内并且适于以扭矩传递关系接合环形齿轮。导丝的近端或可导向导管的引导元件固定到小齿轮上，使得通过壳体的旋转的旋转使得附接的导丝或引导元件的旋转大得多。优选地，提供了用于限制可以赋予导丝或引导装置的旋转次数的装置。

3. 发明申请

US20070027461A1 Tissue connector apparatus and methods 审中-公开
标题翻译：组织连接器装置和方法
公开(公告)号：US20070027461A1
公开(公告)日：2007-02-01
申请号：US11540702
申请日：2006-09-29
申请人： Barry Gardiner , Laurent Schaller , Isidro Gandionco , John Nguyen
发明人： Barry Gardiner , Laurent Schaller , Isidro Gandionco , John Nguyen
IPC分类号： A61B17/08
CPC分类号： A61B17/06 , A61B17/064 , A61B17/0644 , A61B17/11 , A61B2017/06009 , A61B2017/06057
摘要： A tissue connector assembly having a flexible member and a surgical clip releasably coupled to the flexible member. A needle may be secured to one end portion of the flexible member with the surgical clip coupled to the other end portion of the flexible member. A locking device may be used to couple the flexible member to the surgical clip. A method for connecting tissues is also disclosed. The method includes drawing tissue portions together with a clip assembly and securing the tissue portions together with the clip assembly.
摘要翻译：一种组织连接器组件，其具有可释放地联接到柔性构件的柔性构件和外科夹具。针可以被固定到柔性构件的一个端部，而手术夹固定在柔性构件的另一端部上。可以使用锁定装置将柔性构件联接到手术夹。还公开了连接组织的方法。该方法包括将组织部分与夹子组件一起绘图，并将组织部分与夹子组件一起固定。

4. 发明申请

US20050075667A1 Tissue connector apparatus and methods 有权
标题翻译：组织连接器装置和方法
公开(公告)号：US20050075667A1
公开(公告)日：2005-04-07
申请号：US10653027
申请日：2003-08-28
申请人： Laurent Schaller , Barry Gardiner , Art Hill , John Nguyen , Liem Ho , Isidro Gandionco
发明人： Laurent Schaller , Barry Gardiner , Art Hill , John Nguyen , Liem Ho , Isidro Gandionco
IPC分类号： A61B17/04 , A61B17/06 , A61B17/064 , A61B17/11 , A61B17/00
CPC分类号： A61B17/064 , A61B17/0469 , A61B17/06 , A61B17/0644 , A61B17/11 , A61B2017/06009 , A61B2017/06057 , A61B2017/1107 , A61B2017/1135
摘要： Tissue connector assemblies having at least two piercing members, each releaseably coupled to a surgical fastener such as a surgical clip. A flexible member such as a suture may be used to couple one or both piercing members to respective ends of the fastener.
摘要翻译：组织连接器组件具有至少两个穿刺构件，每个穿孔构件可释放地联接到诸如手术夹子的手术紧固件。可以使用诸如缝合线的柔性构件将一个或两个刺穿构件联接到紧固件的相应端部。

5. 发明申请

US20050245862A1 Torque mechanism for interventional catheters 审中-公开
标题翻译：介入导管的扭矩机制
公开(公告)号：US20050245862A1
公开(公告)日：2005-11-03
申请号：US11112871
申请日：2005-04-21
申请人： Kirk Seward , Isidro Gandionco
发明人： Kirk Seward , Isidro Gandionco
IPC分类号： A61M25/01
CPC分类号： A61M25/0133
摘要： A torque mechanism for interventional catheters provides direct control over rotary positioning of the distal end of a catheter by rotating a proximal handle of the catheter. The torque mechanism comprises a stiff tube within and running the length of a flexible catheter body tube. The stiff tube is bonded at its distal end to the catheter body tubing and at its proximal end to a rotary handle. Catheter body tubing is bonded at its proximal end to a catheter hub. The catheter hub and rotary handle rotate independently, thus torque and position are transmitted by the torque tube while the catheter tube acts as a torsional spring.
摘要翻译：用于介入导管的扭矩机构通过旋转导管的近侧手柄来提供对导管远端的旋转定位的直接控制。扭矩机构包括在柔性导管体管的内部并且运行柔性导管体管的长度的刚性管。刚性管在其远端处接合到导管主体管并且其近端处于旋转手柄。导管体管在其近端处结合到导管毂。导管套管和旋转手柄独立旋转，因此扭矩和位置由导管传递，而导管作为扭转弹簧。

6. 发明授权

US06378218B2 Methods and apparatus for making a drug infusion device 失效
标题翻译：制备药物输注装置的方法和装置
公开(公告)号：US06378218B2
公开(公告)日：2002-04-30
申请号：US09068635
申请日：1998-10-19
申请人： Ulrich Sigwart , Amir Abolfathi , Farhad Khosravi , Isidro Gandionco
发明人： Ulrich Sigwart , Amir Abolfathi , Farhad Khosravi , Isidro Gandionco
IPC分类号： B26F132
CPC分类号： B26F1/36 , B26F1/0015 , B26F1/24 , Y10T83/04 , Y10T83/0481
摘要： Methods and apparatus are provided for converting standard catheters or balloon catheters into drug infusion devices on an as-needed basis in a sterile environment, and which permit re-use of catheter devices previously used in a preceding non-invasive procedure. Apparatus is provided having a cavity for receiving a catheter device and a plurality of perforation pins or teeth for creating apertures in the catheter. Apparatus capable of converting a wide range of catheter devices into drug infusion devices is provided, which apparatus may be single-use disposable or re-sterilizable and re-usable.
摘要翻译：提供了用于在无菌环境中根据需要将标准导管或气囊导管转换成药物输注装置的方法和装置，并且其允许重新使用先前在先前非侵入性手术中使用的导管装置。提供具有用于接收导管装置的空腔和用于在导管中产生孔的多个穿孔针或齿的装置。提供了能够将各种导管装置转换成药物输注装置的装置，该装置可以是一次性使用的或可再消毒的并可重新使用。

7. 发明授权

US4907332A Device for connecting extendable guidewire sections for cardiovascular procedures 失效
标题翻译：用于连接用于心血管程序的可延伸导丝部分的装置
公开(公告)号：US4907332A
公开(公告)日：1990-03-13
申请号：US142070
申请日：1988-01-11
申请人： Jeffrey J. Christian , Ross Gould , Isidro Gandionco
发明人： Jeffrey J. Christian , Ross Gould , Isidro Gandionco
IPC分类号： A61M25/01 , B25B11/00 , B25B27/00
CPC分类号： A61M25/0905 , A61M25/09 , B25B11/00 , B25B27/00 , Y10S604/905 , Y10T29/5367 , Y10T29/53678
摘要： A device to facilitate the joining of a male proximal end of a guidewire to the female end of an extension wire. The device has a relatively flat body with a guiding groove in the upper surface with two aligned sections, the goove sections tapering inwardly toward the intersection thereof. One of the groove sections is adapted to receive the male end of the guidewire and one groove is adapted to receive the female end of the extension. One, preferably two, flexible tabs are secured to the upper surface of the body to maintain one of the ends within its respective groove section. The device and/or the connecting wires can be disengaged by the rotation thereof with respect to each other.
摘要翻译：一种便于将导线的阳性近端连接到延长线的阴端的装置。该装置具有相对扁平的主体，在上表面具有引导槽，其具有两个对准的部分，所述凹槽部分朝向其相交处向内逐渐变细。一个槽部适于接收导丝的阳端，一个槽适于接收延伸部的阴端。一个，优选两个柔性突片固定到主体的上表面，以将一个端部保持在其相应的凹槽部分内。装置和/或连接线可以通过其相对于彼此的旋转而脱离。

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