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1. 发明授权

US09005144B2 Tissue-retaining systems for ultrasound medical treatment 有权
标题翻译：用于超声医疗的组织保持系统
公开(公告)号：US09005144B2
公开(公告)日：2015-04-14
申请号：US13719172
申请日：2012-12-18
申请人： Michael H. Slayton , Inder Raj Makin , Robert Dunki-Jacobs , Richard C. Pellegrino
发明人： Michael H. Slayton , Inder Raj Makin , Robert Dunki-Jacobs , Richard C. Pellegrino
IPC分类号： A61N7/00 , A61B8/12 , A61B8/00 , A61B17/32 , A61N7/02 , A61B10/02 , A61B17/22 , A61B17/29 , A61B19/00
CPC分类号： A61N7/00 , A61B8/12 , A61B8/445 , A61B8/4488 , A61B10/0233 , A61B17/22012 , A61B17/2202 , A61B17/29 , A61B17/320092 , A61B2090/378 , A61B2090/3784 , A61B2090/3929 , A61B2090/3975 , A61N7/022 , A61N2007/0078
摘要： An ultrasound medical treatment system includes an end effector insertable into a patient. The end effector includes a tissue-retaining device. The tissue-retaining device includes a first tissue-retaining member having an ultrasound medical-treatment transducer and includes a second tissue-retaining member. The first and second tissue-retaining members are operatively connected together to retain patient tissue between the first and second tissue-retaining members and to release patient tissue so retained. In one example, the second tissue-retaining member has an ultrasound reflector. In the same or a different example, the ultrasound medical-treatment transducer is an ultrasound imaging and medical-treatment transducer.
摘要翻译：超声医疗系统包括可插入病人的末端执行器。末端执行器包括组织保持装置。组织保持装置包括具有超声波医疗换能器的第一组织保持构件，并且包括第二组织保持构件。第一和第二组织保持构件可操作地连接在一起以将患者组织保持在第一和第二组织保持构件之间并且释放如此保留的患者组织。在一个示例中，第二组织保持构件具有超声波反射器。在相同或不同的示例中，超声医疗换能器是超声成像和医疗换能器。

2. 发明申请

US20080071165A1 Imaging and therapeutic procedure for carpal tunnel syndrome 审中-公开
标题翻译：腕管综合征的成像和治疗程序
公开(公告)号：US20080071165A1
公开(公告)日：2008-03-20
申请号：US11983851
申请日：2007-11-13
申请人： Inder Raj Makin , Conrad Klotz , Sarah Stephens , Robert Dunki-Jacobs
发明人： Inder Raj Makin , Conrad Klotz , Sarah Stephens , Robert Dunki-Jacobs
IPC分类号： A61N7/02 , A61B5/055
CPC分类号： A61N7/02 , A61B8/14 , A61B2090/374 , A61B2090/378 , A61N2007/0078
摘要： A system, method and/or apparatus is provided for visualization or imaging of the transverse carpal ligament and surrounding structures/features of a hand of a patient, and treatment of the transverse carpal ligament, particularly, but not necessarily, for performing non-invasive carpal tunnel release. The subject invention utilizes ultrasound waves preferably, but not necessarily, in the high frequency range and cavitations to image the transverse carpal ligament (TCL), record its location in three-dimensional space, and perform precision treatment on the transverse carpal ligament. Treatment may range from stretching or lengthening the TCL to complete tissue ablation or dissection of a portion or portions of the TCL (as is performed in a standard carpal tunnel release procedure) in order to release pressure within the carpal tunnel. Particularly, high temperature conditions are generated at target tissue of the TCL resulting in elongation or necrosis/dissection. The subject system, apparatus and/or method provides the surgeon to relieve a patient of carpal tunnel syndrome symptoms in a bloodless, efficient, and accurate manner.
摘要翻译：提供了一种系统，方法和/或装置，用于横向腕韧带和患者的手的周围结构/特征的可视化或成像，以及横向腕韧带的治疗，特别地但不一定用于执行非侵入性腕管释放。本发明优选但不一定在高频范围内使用超声波，并且对横向腕韧带（TCL）进行成像的空化，将其位置记录在三维空间中，并对横腕腕韧带进行精确的处理。治疗可以从拉伸或延长TCL到完成组织消融或TCL的一部分或部分的解剖（如在标准腕管释放程序中执行的）以释放腕管内的压力。特别地，在TCL的靶组织处产生高温条件，导致伸长或坏死/解剖。受试者系统，装置和/或方法提供外科医生以无血型，有效率和准确的方式缓解患者腕管综合征症状。

3. 发明申请

US20050261585A1 Ultrasound medical system 有权
标题翻译：超声医疗系统
公开(公告)号：US20050261585A1
公开(公告)日：2005-11-24
申请号：US10850038
申请日：2004-05-20
申请人： Inder Raj Makin , T. Mast , Michael Slayton , Peter Barthe , Jeffrey Messerly , Waseem Faidi , Megan Runk , Paul Jaeger
发明人： Inder Raj Makin , T. Mast , Michael Slayton , Peter Barthe , Jeffrey Messerly , Waseem Faidi , Megan Runk , Paul Jaeger
IPC分类号： A61B5/00 , A61B5/05 , A61B5/053 , A61B8/00 , A61B8/12 , A61B8/14 , A61B17/00 , A61B17/22 , A61N7/02
CPC分类号： A61B8/445 , A61B5/01 , A61B5/053 , A61B8/12 , A61B8/4272 , A61B17/2202 , A61B2017/00084 , A61B2017/22034 , A61B2017/22054 , A61B2017/22069 , A61N7/022
摘要： An ultrasound medical system includes an ultrasound end effector and at least one non-ultrasound tissue-property-measuring sensor. The ultrasound end effector includes a medical ultrasound transducer assembly having at least one medical-treatment ultrasound transducer. The at-least-one non-ultrasound tissue-property-measuring sensor is supported by the ultrasound end effector and is positionable in contact with patient tissue.
摘要翻译：超声波医疗系统包括超声末端执行器和至少一个非超声组织特性测量传感器。超声末端执行器包括具有至少一个医疗超声换能器的医用超声换能器组件。所述至少一个非超声组织特性测量传感器由所述超声末端执行器支撑并且可定位成与患者组织接触。

4. 发明申请

US20060241442A1 METHOD AND SYSTEM FOR TREATING PHOTOAGED TISSUE 有权
标题翻译：用于处理光泽组织的方法和系统
公开(公告)号：US20060241442A1
公开(公告)日：2006-10-26
申请号：US11163150
申请日：2005-10-06
申请人： Peter Barthe , Michael Slayton , Inder Raj Makin
发明人： Peter Barthe , Michael Slayton , Inder Raj Makin
IPC分类号： A61B8/00 , A61H1/00
CPC分类号： A61N7/02 , A61B5/682 , A61B5/6842 , A61B8/08 , A61B8/0858 , A61B8/12 , A61B8/13 , A61B8/4209 , A61B8/4281 , A61B8/4455 , A61B8/4483 , A61B8/461 , A61B8/483 , A61B8/546 , A61B17/320068 , A61H23/0245 , A61H2201/5007 , A61N7/00 , A61N2007/0008 , A61N2007/0034 , A61N2007/0052 , A61N2007/027 , G01S15/8909
摘要： A method and system for ultrasound treatment of photoaged tissue are provided. An exemplary method and system are configured for first, ultrasound imaging of the region of interest for localization of the treatment area, second, delivery of ultrasound energy at a depth and pattern to achieve the desired therapeutic effects, and third to monitor the treatment area during and after therapy to assess the results and/or provide feedback. The exemplary treatment method and system can be configured for producing arrays of sub-millimeter and larger zones of thermal ablation to treat the epidermal, superficial dermal, mid-dermal and deep dermal components of photoaged tissue.
摘要翻译：提供了一种用于光电组织超声处理的方法和系统。一种示例性方法和系统被配置用于首先对感兴趣区域的超声成像进行治疗区域的定位，其次，以深度和图案递送超声能量以获得期望的治疗效果，第三，监测治疗区域的治疗区域并在治疗后评估结果和/或提供反馈。可以将示例性治疗方法和系统配置用于产生亚毫米和更大的热消融区域阵列，以治疗光化组织的表皮，浅表皮肤，中间皮肤和深层真皮成分。

5. 发明申请

US20050256405A1 Ultrasound-based procedure for uterine medical treatment 审中-公开
标题翻译：基于超声的子宫手术治疗
公开(公告)号：US20050256405A1
公开(公告)日：2005-11-17
申请号：US10847209
申请日：2004-05-17
申请人： Inder Raj Makin , Yoav Avidor , Peter Barthe , Michael Slayton
发明人： Inder Raj Makin , Yoav Avidor , Peter Barthe , Michael Slayton
IPC分类号： A61B8/12 , A61B17/32 , A61B17/42
CPC分类号： A61B8/12 , A61B5/489 , A61B2017/320069 , A61B2017/320071 , A61B2017/320094 , A61B2017/320095 , A61B2017/4216
摘要： A first method for ultrasound uterine medical treatment includes obtaining an end effector having an ultrasound medical-treatment transducer assembly, identifying a blood vessel which supplies blood to a portion of the uterus, and medically treating the blood vessel with ultrasound from the transducer assembly to substantially seal the blood vessel to substantially stop the supply of blood from the blood vessel to the portion of the uterus. In one example, shrinkage of a uterine fibroid is accomplished through use of the end effector endoscopically inserted into the uterus. A second method for ultrasound uterine medical treatment includes endoscopically inserting the end effector into the uterus and medically treating the endometrium lining with ultrasound from the transducer assembly to ablate a desired thickness of at least a portion of the endometrium lining to substantially stop abnormal uterine bleeding from the endometrium lining.
摘要翻译：用于超声子宫疗法的第一种方法包括获得具有超声波医疗换能器组件的端部执行器，其识别向子宫的一部分供血的血管，以及用换能器组件的超声医用血管密封血管以基本上停止从血管向子宫的部分供血。在一个实例中，子宫肌瘤的收缩通过使用内窥镜插入到子宫中的末端执行器完成。用于超声子宫治疗的第二种方法包括将末端执行器内窥镜地插入子宫，并用来自换能器组件的超声医学治疗子宫内膜衬里，以消融子宫内膜衬垫的至少一部分的期望厚度，以基本上阻止异常子宫出血子宫内膜衬里。

6. 发明申请

US20050240125A1 Medical system having multiple ultrasound transducers or an ultrasound transducer and an RF electrode 有权
标题翻译：具有多个超声换能器或超声波换能器和RF电极的医疗系统
公开(公告)号：US20050240125A1
公开(公告)日：2005-10-27
申请号：US10825952
申请日：2004-04-16
申请人： Inder Raj Makin , T. Mast , Michael Slayton , Peter Barthe , Jeffrey Messerly , Waseem Faidi , Megan Runk
发明人： Inder Raj Makin , T. Mast , Michael Slayton , Peter Barthe , Jeffrey Messerly , Waseem Faidi , Megan Runk
IPC分类号： A61B8/00 , A61B8/12 , A61B18/14 , A61B19/00 , A61H1/00 , A61H23/02 , A61N7/00 , A61N7/02
CPC分类号： A61B8/445 , A61B8/12 , A61B18/148 , A61B2090/378 , A61H23/0245 , A61N7/02 , A61N2007/0078
摘要： An ultrasound medical system includes an ultrasound transducer assembly having various combinations of ultrasound transducers having different-shaped ultrasound emitting surfaces and/or different ultrasound transducer types, wherein the types are ultrasound-medical-treatment-only type, ultrasound-medical-treatment-and-imaging type, and ultrasound-medical-imaging-only type ultrasound transducers. Another ultrasound medical system includes a transducer assembly having an RF (radio-frequency) medical-treatment electrode and an ultrasound medical transducer.
摘要翻译：超声波医疗系统包括具有不同形状的超声波发射表面和/或不同超声换能器类型的超声换能器的各种组合的超声换能器组件，其中所述类型是超声医疗治疗类型，超声医疗治疗和成像型和超声医学成像型超声换能器。另一种超声波医疗系统包括具有RF（射频）医疗电极和超声医疗换能器的换能器组件。

7. 发明申请

US20060079868A1 METHOD AND SYSTEM FOR TREATMENT OF BLOOD VESSEL DISORDERS 审中-公开
标题翻译：用于治疗血管病变的方法和系统
公开(公告)号：US20060079868A1
公开(公告)日：2006-04-13
申请号：US11163176
申请日：2005-10-07
申请人： Inder Raj Makin , Michael Slayton , Peter Barthe
发明人： Inder Raj Makin , Michael Slayton , Peter Barthe
IPC分类号： A61B18/04
CPC分类号： A61N7/02 , A61B8/4281 , A61B8/429 , A61B2017/00756 , A61N2007/0008 , A61N2007/0078
摘要： A non-invasive method and system for using ultrasound energy for the treatment of conditions resulting from vascular disorders is provided. In one embodiment, an image-treatment approach can be used to locate the blood vessel to be treated and then to ablate it non-invasively, while also monitoring the progress of the treatment. In another embodiment, a transducer is configured to deliver ultrasound energy to the regions of the superficial tissue (e.g., skin) such that the energy is deposited at the particular depth at which the vascular malformations (such as but not limited to varicose veins) are located below the skin surface. The ultrasound transducer can be driven at a number of different frequency regimes such that the depth and shape of energy concentration can match the region of treatment.
摘要翻译：提供了一种使用超声能量治疗由血管疾病引起的病症的非侵入性方法和系统。在一个实施例中，可以使用图像处理方法来定位待治疗的血管，然后非侵入性地消融，同时还监视治疗进展。在另一个实施例中，换能器被配置为将超声能量递送到浅表组织（例如，皮肤）的区域，使得能量在血管畸形（例如但不限于静脉曲张）的特定深度处被沉积位于皮肤表面下方。超声波传感器可以以多种不同的频率方式驱动，使得能量浓度的深度和形状可以与治疗区域相匹配。

8. 发明申请

US20060079816A1 METHOD AND SYSTEM FOR TREATING STRETCH MARKS 有权
公开(公告)号：US20060079816A1
公开(公告)日：2006-04-13
申请号：US11163178
申请日：2005-10-07
申请人： Peter Barthe , Michael Slayton , Inder Raj Makin
发明人： Peter Barthe , Michael Slayton , Inder Raj Makin
IPC分类号： A61H1/00
CPC分类号： A61N7/02 , A61B8/14 , A61B8/4281 , A61B8/429 , A61B8/4444 , A61B8/4455 , A61B8/4483 , A61B8/461 , A61B8/483 , A61B8/5223 , A61B8/54 , A61H23/0245 , A61H2201/0214 , A61H2201/5064 , A61H2201/5082 , A61H2207/00 , A61N2007/0008 , A61N2007/0034 , A61N2007/0052 , A61N2007/0056 , A61N2007/0073 , A61N2007/0078 , G01S15/8909
摘要： Methods and systems for treating stretch marks through deep tissue tightening with ultrasound are provided. An exemplary method and system comprise a therapeutic ultrasound system configured for providing ultrasound treatment to a shallow tissue region, such as a region comprising an epidermis, a dermis and a deep dermis. In accordance with various exemplary embodiments, a therapeutic ultrasound system can be configured to achieve depth from 0 mm to 1 cm with a conformal selective deposition of ultrasound energy without damaging an intervening tissue in the range of frequencies from 2 to 50 MHz. In addition, a therapeutic ultrasound can also be configured in combination with ultrasound imaging or imaging/monitoring capabilities, either separately configured with imaging, therapy and monitoring systems or any level of integration thereof.

9. 发明申请

US20060074314A1 METHOD AND SYSTEM FOR NONINVASIVE MASTOPEXY 有权
公开(公告)号：US20060074314A1
公开(公告)日：2006-04-06
申请号：US11163155
申请日：2005-10-06
申请人： Michael Slayton , Peter Barthe , Inder Raj Makin
发明人： Michael Slayton , Peter Barthe , Inder Raj Makin
IPC分类号： A61B8/12
CPC分类号： A61N7/02 , A61B8/0825 , A61B8/14 , A61B8/4281 , A61B8/429 , A61B8/4483 , A61B8/461 , A61B8/483 , A61B18/04 , A61B18/18 , A61B2018/00333 , A61B2018/00577 , A61B2018/00642 , A61B2018/00791 , A61B2018/00904 , A61B2018/00994 , A61N2007/0052 , G01S7/52046 , G01S15/8909
摘要： Methods and systems for noninvasive mastopexy through deep tissue tightening with ultrasound are provided. An exemplary method and system comprise a therapeutic ultrasound system configured for providing ultrasound treatment to a deep tissue region, such as a region comprising muscular fascia and ligaments. In accordance with various exemplary embodiments, a therapeutic ultrasound system can be configured to achieve depth from 1 mm to 4 cm with a conformal selective deposition of ultrasound energy without damaging an intervening tissue in the range of frequencies from 1 to 15 MHz. In addition, a therapeutic ultrasound can also be configured in combination with ultrasound imaging or imaging/monitoring capabilities, either separately configured with imaging, therapy and monitoring systems or any level of integration thereof.

10. 发明申请

US20060074313A1 METHOD AND SYSTEM FOR TREATING CELLULITE 有权
标题翻译：处理细胞的方法和系统
公开(公告)号：US20060074313A1
公开(公告)日：2006-04-06
申请号：US11163154
申请日：2005-10-06
申请人： Michael Slayton , Peter Barthe , Inder Raj Makin
发明人： Michael Slayton , Peter Barthe , Inder Raj Makin
IPC分类号： A61B8/12
CPC分类号： A61N7/02 , A61B8/14 , A61B8/429 , A61B8/4455 , A61B8/4483 , A61B8/461 , A61B8/483 , A61B2090/378 , A61N7/00 , A61N2007/0008 , G01S15/8906 , G01S15/8936
摘要： A method and system for providing ultrasound treatment to a deep tissue that contains a lower part of dermis and proximal protrusions of fat labuli into the dermis. The invention delivers ultrasound energy to the region creating a thermal injury and coagulating the proximal protrusions of fat labuli, whereby eliminating the fat protrusions into the dermis. The invention can also include ultrasound imaging configurations using the same or a separate probe before, after or during the treatment. In addition various therapeutic levels of ultrasound can be used to increase the speed at which fat metabolizes. Additionally the mechanical action of ultrasound physically breaks fat cell clusters and stretches the fibrous bonds. Mechanical action will also enhance lymphatic drainage, stimulating the evacuation of fat decay products.
摘要翻译：用于向深层组织提供超声处理的方法和系统，所述深部组织含有真皮的下部和脂肪乳突的近端突出部分进入真皮。本发明向该区域提供超声波能量，从而产生热损伤，并使脂肪乳突的近端突起凝结，从而消除了真皮中的脂肪突起。本发明还可以包括在治疗之前，之后或期间使用相同或单独的探针的超声成像构造。此外，可以使用各种治疗水平的超声波来增加脂肪代谢的速度。另外，超声的机械作用物理地破坏脂肪细胞簇并延伸纤维结合。机械作用也会增强淋巴引流，刺激排出脂肪衰变产物。

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