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1. 发明授权

US5591403A Portable prothrombin time test apparatus and associated method of performing a prothrombin time test 失效
标题翻译：便携式凝血酶原时间检测装置及其相关方法进行凝血酶原时间检测
公开(公告)号：US5591403A
公开(公告)日：1997-01-07
申请号：US617296
申请日：1996-03-18
申请人： Michael Gavin , Catherine M. Cimini , Ming Huang , Anthony Kuklo, Jr. , James A. Mawhirt , Eduardo Marcelino , Albert Simone
发明人： Michael Gavin , Catherine M. Cimini , Ming Huang , Anthony Kuklo, Jr. , James A. Mawhirt , Eduardo Marcelino , Albert Simone
IPC分类号： G01N33/49 , G01N33/86 , G01N37/00
CPC分类号： G01N33/4905 , G01N33/86 , Y10T436/10
摘要： A portable device for performing coagulation tests on a patient's blood. Blood is first drawn from a patient using a lancet. The blood is then supplied to a disposable cuvette placed within the testing device. The blood is drawn into multiple conduits within the cuvette. Each of the conduits contains a dried or lyophilized activation reagent that is rehydrated by the blood. The blood in each of the conduits is then reciprocally moved across a restricted region until a predetermined degree of coagulation occurs. Since the coagulation time is being monitored in multiple conduits, a representation coagulation time for a given sample can be determined. In at least one of the conduits a normalizing control agent is present. The normalizing control agent counteracts any effects of anticoagulants present in the blood sample, thereby allowing the blood sample to have generally normal coagulation characteristics. The normalized blood is tested simultaneously with the untreated blood to provide a reference value against which the functionality of the test system and the quality of the sample can be judged.
摘要翻译：一种用于对患者血液进行凝血测试的便携式装置。首先使用刺血针从患者抽血。然后将血液供应到放置在测试装置内的一次性比色皿。血液被吸入比色皿内的多个管道。每个管道含有由血液再水合的干燥或冻干的活化剂。每个导管中的血液然后往复运动跨越限制区域，直到发生预定的凝结程度。由于在多个管道中监测凝固时间，因此可以确定给定样品的凝固时间。在至少一个导管中存在归一化控制剂。归一化控制剂抵抗血液样品中存在的抗凝血剂的任何作用，从而允许血液样品具有大致正常的凝血特性。与未处理的血液同时测试归一化的血液，以提供参考值，可以判断测试系统的功能和样品的质量。

2. 发明授权

US5800781A Blood sampling device 失效
标题翻译：采血装置
公开(公告)号：US5800781A
公开(公告)日：1998-09-01
申请号：US719779
申请日：1996-09-25
申请人： Michael Gavin , Catherine M. Cimini , Ming Huang , Anthony Kuklo, Jr. , James A. Mawhirt , Eduardo Marcelino , Albert Simone
发明人： Michael Gavin , Catherine M. Cimini , Ming Huang , Anthony Kuklo, Jr. , James A. Mawhirt , Eduardo Marcelino , Albert Simone
IPC分类号： G01N33/49 , G01N33/86 , G01N37/00
CPC分类号： G01N33/4905 , G01N33/86 , Y10T436/10
摘要： A portable device for performing coagulation tests on a patient's blood. Blood is first drawn from a patient using a lancet. The blood is then supplied to a disposable cuvette placed within the testing device. The blood is drawn into multiple conduits within the cuvette. Each of the conduits contains a dried or lyophilized activation reagent that is rehydrated by the blood. The blood in each of the conduits is then reciprocally moved across a restricted region until a predetermined degree of coagulation occurs. Since the coagulation time is being monitored in multiple conduits, a representation coagulation time for a given sample can be determined. In at least one of the conduits a normalizing control agent is present. The normalizing control agent counteracts any effects of anticoagulants present in the blood sample, thereby allowing the blood sample to have generally normal coagulation characteristics. The normalized blood is tested simultaneously with the untreated blood to provide a reference value against which the functionality of the test system and the quality of the sample can be judged.
摘要翻译：一种用于对患者血液进行凝血测试的便携式装置。首先使用刺血针从患者抽血。然后将血液供应到放置在测试装置内的一次性比色皿。血液被吸入比色皿内的多个管道。每个管道含有由血液再水合的干燥或冻干的活化剂。每个导管中的血液然后往复运动跨越限制区域，直到发生预定的凝结程度。由于在多个管道中监测凝固时间，因此可以确定给定样品的凝固时间。在至少一个导管中存在归一化控制剂。归一化控制剂抵抗血液样品中存在的抗凝血剂的任何作用，从而允许血液样品具有大致正常的凝血特性。与未处理的血液同时测试归一化的血液，以提供参考值，可以判断测试系统的功能和样品的质量。

3. 发明授权

US5504011A Portable test apparatus and associated method of performing a blood coagulation test 失效
标题翻译：便携式试验装置及进行凝血试验的相关方法
公开(公告)号：US5504011A
公开(公告)日：1996-04-02
申请号：US327320
申请日：1994-10-21
申请人： Michael Gavin , Catherine M. Cimini , Ming Huang , Anthony Kuklo, Jr. , James A. Mawhirt , Eduardo Marcelino , Albert Simone
发明人： Michael Gavin , Catherine M. Cimini , Ming Huang , Anthony Kuklo, Jr. , James A. Mawhirt , Eduardo Marcelino , Albert Simone
IPC分类号： G01N33/49 , G01N33/86 , G01N37/00
CPC分类号： G01N33/4905 , G01N33/86 , Y10T436/10
摘要： A portable device for performing coagulation tests on a patient's blood. Blood is first drawn from a patient using a lancet. The blood is then supplied to a disposable cuvette placed within the testing device. The blood is drawn into multiple conduits within the cuvette. Each of the conduits contains a dried or lyophilized activation reagent that is rehydrated by the blood. The blood in each of the conduits is then reciprocally moved across a restricted region until a predetermined degree of coagulation occurs. Since the coagulation time is being monitored in multiple conduits, a representation coagulation time for a given sample can be determined. In at least one of the conduits a normalizing control agent is present. The normalizing control agent counteracts any effects of anticoagulants present in the blood sample, thereby allowing the blood sample to have generally normal coagulation characteristics. The normalized blood is tested simultaneously with the untreated blood to provide a reference value against which the functionality of the test system and the quality of the sample can be judged.
摘要翻译：一种用于对患者血液进行凝血测试的便携式装置。首先使用刺血针从患者抽血。然后将血液供应到放置在测试装置内的一次性比色皿。血液被吸入比色皿内的多个管道。每个管道含有由血液再水合的干燥或冻干的活化剂。每个导管中的血液然后往复运动跨越限制区域，直到发生预定的凝结程度。由于在多个管道中监测凝固时间，因此可以确定给定样品的凝固时间。在至少一个导管中存在归一化控制剂。归一化控制剂抵抗血液样品中存在的抗凝血剂的任何作用，从而允许血液样品具有大致正常的凝血特性。与未处理的血液同时测试归一化的血液，以提供参考值，可以判断测试系统的功能和样品的质量。

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