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1. 发明申请

US20050000518A1 Aerosolization apparatus with capsule puncture alignment guide 审中-公开
标题翻译：胶囊穿刺对准导管的气雾化装置
公开(公告)号：US20050000518A1
公开(公告)日：2005-01-06
申请号：US10821624
申请日：2004-04-09
申请人： Michael Dunkley , Jon Tuckwell , Edward Vernon-Harcourt , Mark Glusker , Steve Paboojian
发明人： Michael Dunkley , Jon Tuckwell , Edward Vernon-Harcourt , Mark Glusker , Steve Paboojian
IPC分类号： A61M15/00
CPC分类号： A61M15/0028 , A61M15/0033 , A61M2202/064
摘要： An aerosolization apparatus comprises a housing defining a chamber having one or more air inlets. The chamber is sized to receive a capsule which contains an aerosolizable pharmaceutical formulation. The aerosolization apparatus further comprises a puncturing mechanism within the housing. The puncturing mechanism comprises an alignment guide and a puncture member, wherein the alignment guide comprises a surface adapted to contact the capsule while the puncture member is advanced into the capsule to create an opening in the capsule. At least a portion of the surface is sloped relative to the longitudinal axis of the capsule. Alternatively or additionally, the surface may comprise one or more protrusions. An end section is associated with the housing. The end section is sized and shaped to be received in a user's mouth or nose so that the user may inhale through the end section to inhale aerosolized pharmaceutical formulation that has exited the capsule through the opening created in the capsule. The alignment guide allows for more consistent puncturing of the capsule and a longer lifetime of the apparatus.
摘要翻译：雾化装置包括限定具有一个或多个空气入口的室的壳体。该腔室的大小适于接收含有可雾化药物制剂的胶囊。雾化装置还包括在壳体内的穿刺机构。穿刺机构包括对准引导件和穿刺构件，其中对齐引导件包括适于在穿刺构件前进到胶囊中以接触胶囊的表面以在胶囊中形成开口。表面的至少一部分相对于胶囊的纵向轴线倾斜。或者或另外，表面可以包括一个或多个突起。端部与壳体相关联。端部的尺寸和形状被容纳在使用者的嘴或鼻中，使得使用者可以通过端部部分吸入，以吸入通过在胶囊中形成的开口离开胶囊的雾化药物制剂。对准引导件允许胶囊的更一致的穿刺和装置的更长的使用寿命。

2. 发明申请

US20050150492A1 Aerosolization apparatus with air inlet shield 有权
标题翻译：带进气口罩的气雾化装置
公开(公告)号：US20050150492A1
公开(公告)日：2005-07-14
申请号：US10822850
申请日：2004-04-09
申请人： Michael Dunkley , Jon Tuckwell , Edward Vernon-Harcourt , Sameer Shirgaonkar
发明人： Michael Dunkley , Jon Tuckwell , Edward Vernon-Harcourt , Sameer Shirgaonkar
IPC分类号： A61M15/00 , B05D7/14
CPC分类号： A61M15/0028 , A61M15/003 , A61M15/0033 , A61M2202/064 , A61M2206/16
摘要： An aerosolization apparatus comprises a housing defining a chamber having a plurality of air inlets. The chamber contains an aersolizable pharmaceutical formulation or is sized to receive a receptacle which contains an aerosolizable pharmaceutical formulation. A shield covers at least one of the air inlets or a portion of at least one of the air inlets. The shield prevents blockage of the air inlet by a user grasping the apparatus and inadvertently covering the air inlet. An end section is associated with the housing. The end section is sized and shaped to be received in a user's mouth or nose so that the user may inhale through the end section to inhale aerosolized pharmaceutical formulation that has exited the receptacle.
摘要翻译：雾化装置包括限定具有多个空气入口的腔室的壳体。该腔室含有可溶胶体药物制剂，或者其尺寸适于容纳含有可雾化药物制剂的容器。屏蔽罩覆盖至少一个空气入口或至少一个空气入口的一部分。屏蔽件防止使用者抓住装置堵塞空气入口并且无意中覆盖空气入口。端部与壳体相关联。端部的尺寸和形状被设计成容纳在使用者的嘴或鼻中，使得使用者可以通过端部吸入以吸入已经离开容器的雾化的药物制剂。

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