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1. 发明申请

US20070249810A1 Method to Protect DNA Ends 有权
标题翻译：保护DNA末端的方法
公开(公告)号：US20070249810A1
公开(公告)日：2007-10-25
申请号：US11688706
申请日：2007-03-20
申请人： Michael Cox , Dennis Harris , Sergei Saveliev , John Battista , Edmond Jolivet , Masashi Tanaka , Julie Eggington
发明人： Michael Cox , Dennis Harris , Sergei Saveliev , John Battista , Edmond Jolivet , Masashi Tanaka , Julie Eggington
IPC分类号： C07K14/00 , C07H21/04
CPC分类号： C12N15/10 , C12N15/66 , C12Q1/6806 , C12Q2527/125 , C12Q2525/125
摘要： A method of protecting the 3′ end of a DNA molecule from nuclease damage is disclosed. In one embodiment, the method comprises the step of exposing the DNA molecule to a preparation of DdrA protein.
摘要翻译：公开了保护DNA分子的3'末端免受核酸酶损伤的方法。在一个实施方案中，该方法包括将DNA分子暴露于DdrA蛋白的制备物的步骤。

2. 发明申请

US20060024698A1 Method to protect DNA ends 有权
公开(公告)号：US20060024698A1
公开(公告)日：2006-02-02
申请号：US11123701
申请日：2005-05-06
申请人： Michael Cox , Dennis Harris , Sergei Saveliev , John Battista , Edmond Jolivet , Masashi Tanaka , Julie Eggington
发明人： Michael Cox , Dennis Harris , Sergei Saveliev , John Battista , Edmond Jolivet , Masashi Tanaka , Julie Eggington
IPC分类号： C12Q1/68 , C12P19/34
CPC分类号： C12N15/10 , C12N15/66 , C12Q1/6806 , C12Q2527/125 , C12Q2525/125
摘要： A method of protecting the 3′ end of a DNA molecule from nuclease damage is disclosed. In one embodiment, the method comprises the step of exposing the DNA molecule to a preparation of DdrA protein.

3. 发明授权

US08532729B2 Moldable ear sensor 失效
标题翻译：可成型耳朵传感器
公开(公告)号：US08532729B2
公开(公告)日：2013-09-10
申请号：US13077319
申请日：2011-03-31
申请人： Casey V. Medina , Paul Von Der Lippe , Charles Haisley , David P. Besko , John Battista
发明人： Casey V. Medina , Paul Von Der Lippe , Charles Haisley , David P. Besko , John Battista
IPC分类号： A61B5/1455
CPC分类号： A61B5/14552 , A61B5/02055 , A61B5/02427 , A61B5/6816 , A61B6/4405 , A61B8/4209 , A61B8/4236 , A61B2562/0238 , A61B2562/08 , A61B2562/222
摘要： The present disclosure relates to sensors for use on a patient's ear. The sensors as provided may include a moldable member, such as a putty. The moldable member may be molded in place to affix the optical components of the sensor to a patient's ear tissue. For example, the moldable member may be sculpted around a curvature of a patient's earlobe. In particular embodiments, the moldable member may be activated, e.g., hardened, by exposure to particular temperatures or by exposure to light.
摘要翻译：本公开涉及用于患者耳朵的传感器。所提供的传感器可以包括可模制构件，例如油灰。可模塑构件可以模制在适当位置以将传感器的光学部件固定到患者的耳朵组织。例如，可模制构件可围绕患者耳垂的曲率雕刻。在具体实施方案中，可模制构件可以通过暴露于特定温度或通过暴露于光而被激活，例如硬化。

4. 发明授权

US08768426B2 Y-shaped ear sensor with strain relief 有权
标题翻译： Y型耳朵传感器，具有应力消除
公开(公告)号：US08768426B2
公开(公告)日：2014-07-01
申请号：US13077299
申请日：2011-03-31
申请人： Charles Haisley , David Besko , John Battista , Casey V. Medina , Paul Von Der Lippe
发明人： Charles Haisley , David Besko , John Battista , Casey V. Medina , Paul Von Der Lippe
IPC分类号： A61B5/1455
CPC分类号： A61B5/6815 , A61B5/1455
摘要： The present disclosure relates to sensors for use on a patient's ear. The sensors as provided may be Y-shaped and configured to be retained on an ear with the forks of the Y-shape positioned below the main branch of the Y. In particular embodiments, the Y-shaped sensors may be affixed to the patient at locations on the head or neck to relieve strain and reduce the effects of motion on the optical components of the sensor.
摘要翻译：本公开涉及用于患者耳朵的传感器。所提供的传感器可以是Y形并且被配置为保持在耳朵上，Y形的叉位于Y的主分支下方。在特定实施例中，Y形传感器可以固定在患者身上位于头部或颈部的位置以减轻应变并减少运动对传感器的光学部件的影响。

5. 发明申请

US20120253159A1 MOLDABLE EAR SENSOR 失效
标题翻译：可弯曲的传感器
公开(公告)号：US20120253159A1
公开(公告)日：2012-10-04
申请号：US13077319
申请日：2011-03-31
申请人： Casey V. Medina , Paul Von Der Lippe , Charles Haisley , David P. Besko , John Battista
发明人： Casey V. Medina , Paul Von Der Lippe , Charles Haisley , David P. Besko , John Battista
IPC分类号： A61B5/1455 , A61B6/00
CPC分类号： A61B5/14552 , A61B5/02055 , A61B5/02427 , A61B5/6816 , A61B6/4405 , A61B8/4209 , A61B8/4236 , A61B2562/0238 , A61B2562/08 , A61B2562/222
摘要： The present disclosure relates to sensors for use on a patient's ear. The sensors as provided may include a moldable member, such as a putty. The moldable member may be molded in place to affix the optical components of the sensor to a patient's ear tissue. For example, the moldable member may be sculpted around a curvature of a patient's earlobe. In particular embodiments, the moldable member may be activated, e.g., hardened, by exposure to particular temperatures or by exposure to light.
摘要翻译：本公开涉及用于患者耳朵的传感器。所提供的传感器可以包括可模制构件，例如油灰。可模塑构件可以模制在适当位置以将传感器的光学部件固定到患者的耳朵组织。例如，可模制构件可围绕患者耳垂的曲率雕刻。在具体实施方案中，可模制构件可以通过暴露于特定温度或通过暴露于光而被激活，例如硬化。

6. 发明授权

US6088688A Computerized resource accounting methods and systems, computerized utility management methods and systems, multi-user utility management methods and systems, and energy-consumption-based tracking methods and systems 有权
标题翻译：计算机资源会计方法和系统，计算机化公用事业管理方法和系统，多用途公用事业管理方法和系统以及基于能耗的跟踪方法和系统
公开(公告)号：US6088688A
公开(公告)日：2000-07-11
申请号：US290016
申请日：1999-04-08
申请人： Gerry Crooks , Ed Arnhold , John Battista , Ken Boni , Dan Bowers , Mark Feichtner , Blaine French , Janna Genzberger , David D. Holmes , Larry Kippenhan , Dave Miller , Shawn Nanto , Teri Orr , Ed Schlect
发明人： Gerry Crooks , Ed Arnhold , John Battista , Ken Boni , Dan Bowers , Mark Feichtner , Blaine French , Janna Genzberger , David D. Holmes , Larry Kippenhan , Dave Miller , Shawn Nanto , Teri Orr , Ed Schlect
IPC分类号： G06Q10/06 , G06Q20/04 , G06Q20/10 , G06Q20/14 , G06Q30/02 , G06Q30/04 , G06Q30/06 , G06Q40/00 , G06Q50/06 , H02J3/00 , G06F17/60
CPC分类号： G06Q10/06 , G06Q10/06311 , G06Q20/04 , G06Q20/102 , G06Q20/14 , G06Q30/0283 , G06Q30/04 , G06Q30/06 , G06Q40/12 , G06Q50/06 , H02J3/008 , G06Q40/125 , Y04S10/60 , Y04S50/10 , Y04S50/12 , Y04S50/14 , Y10S707/99945 , Y10S707/99948
摘要： Computerized resource accounting methods and systems, and in particular computerized utility resource management methods and systems, multi-user utility resource management methods and systems, and energy-consumption-based tracking methods and systems are described. In one implementation, a host computer includes a processor, an interface device and a database defined therein for maintaining information pertaining to one or more customers of one or more resources. Resource usage information is received into the host computer pertaining to consumption of one or more of the resources by one or more of the customers at one or more customer site. The resource usage information is processed to provide usage-based, computer-viewable data associated with a respective customer's consumption of one or more of the resources. In a preferred aspect, each customer is provided with computer access to the computer-viewable data through the interface device, wherein the customer can view the data at a location which is remote from the host computer. Preferably, the computer-viewable data comes in the form of a plurality of different graphical reports, including numerical and tabulated reports, which can be selected by a customer. For customers with multiple sites, the viewable data for the various sites can be viewed remotely and in a plurality of different report formats. In a preferred implementation, utility resource usage information, e.g. electricity, gas, water, etc . . . , is tracked, maintained, and made available to facilitate decision making.
摘要翻译：描述了计算机资源会计方法和系统，特别是计算机化的公用事业资源管理方法和系统，多用户实用程序资源管理方法和系统以及基于能量消耗的跟踪方法和系统。在一个实现中，主计算机包括处理器，接口设备和在其中定义的数据库，用于维护与一个或多个资源的一个或多个客户有关的信息。资源使用信息被接收到主计算机中，涉及由一个或多个客户站点中的一个或多个客户消费一个或多个资源。处理资源使用信息以提供与相应客户对一个或多个资源的消费相关联的基于用户的可计算机可见数据。在优选的方面，通过接口设备向每个客户提供对计算机可浏览数据的计算机访问，其中客户可以在远离主计算机的位置处查看数据。优选地，计算机可视数据以多种不同的图形报告的形式出现，包括可以由客户选择的数字和制表报告。对于具有多个站点的客户，可以远程查看各种站点的可查看数据，并以多种不同的报告格式进行查看。在优选实施例中，公用事业资源使用信息，例如，电，煤气，水等。。。，被跟踪，维护和提供，以便于决策。

7. 发明申请

US20120253152A1 Y-SHAPED EAR SENSOR WITH STRAIN RELIEF 有权
标题翻译：具有应变消除的Y型传感器
公开(公告)号：US20120253152A1
公开(公告)日：2012-10-04
申请号：US13077299
申请日：2011-03-31
申请人： Charles Haisley , David Besko , John Battista , Casey V. Medina , Paul Von Der Lippe
发明人： Charles Haisley , David Besko , John Battista , Casey V. Medina , Paul Von Der Lippe
IPC分类号： A61B5/1455
CPC分类号： A61B5/6815 , A61B5/1455
摘要： The present disclosure relates to sensors for use on a patient's ear. The sensors as provided may be Y-shaped and configured to be retained on an ear with the forks of the Y-shape positioned below the main branch of the Y. In particular embodiments, the Y-shaped sensors may be affixed to the patient at locations on the head or neck to relieve strain and reduce the effects of motion on the optical components of the sensor.
摘要翻译：本公开涉及用于患者耳朵的传感器。所提供的传感器可以是Y形并且被配置为保持在耳朵上，Y形的叉位于Y的主分支下方。在特定实施例中，Y形传感器可以固定在患者身上位于头部或颈部的位置以减轻应变并减少运动对传感器的光学部件的影响。

8. 发明授权

US6052671A Computerized bill consolidation, billing and payment authorization with remote access to the billing information 有权
标题翻译：计算机帐单合并，计费和付款授权，远程访问计费信息
公开(公告)号：US6052671A
公开(公告)日：2000-04-18
申请号：US287394
申请日：1999-04-06
申请人： Gerry Crooks , Janna Genzberger , Ed Arnhold , John Battista , Ken Boni , Dave Miller , Mark Feichtner , Larry Kippenhan , Shawn Nanto , Teri Orr , Dan Bowers
发明人： Gerry Crooks , Janna Genzberger , Ed Arnhold , John Battista , Ken Boni , Dave Miller , Mark Feichtner , Larry Kippenhan , Shawn Nanto , Teri Orr , Dan Bowers
IPC分类号： G06Q20/04 , G06Q20/14 , G06Q30/02 , G06Q30/04 , G06Q40/00 , G06Q50/06 , G06F17/60
CPC分类号： G06Q30/04 , G06Q20/04 , G06Q20/14 , G06Q30/0283 , G06Q40/12 , G06Q50/06 , Y10S707/99945 , Y10S707/99948
摘要： Computerized billing and payment authorization methods and systems are described. In one aspect, a host system includes a database in which information associated with a billable entity from which payment is to be received is stored. Billing information is received from a billing entity and is associated with a bill for payment by the billable entity. The billable entity is provided with remote electronic access to the billing information in the host computer and can authorization payment thereof. In one implementation, the billing information is scrutinized in accordance with pre-determined tolerance parameters prior to the billable entity gaining access thereto. In another implementation, a plurality of billing entities provide billing information to the host system, with the billing information being subsequently checked and consolidated into a consolidated amount which can be remotely accessed by the billable entity. In a preferred implementation a plurality of utility providers are incorporated into the system and providing billing information for customers which may have a number of different, geographically-separated sites being serviced by different utilities. The billing information is consolidated and made available electronically through access which is initiated by the customer. Preferably, the systems and methodologies of the invention are implemented in connection with a multi-user computer network such as the Internet.
摘要翻译：描述了计算机化的计费和支付授权方法和系统。一方面，主机系统包括数据库，其中存储有与要从其接收支付的可计费实体相关联的信息。计费信息从计费实体接收，并且与可结算实体的支付账单相关联。可计费实体被提供对主计算机中的计费信息的远程电子访问，并且可以对其进行授权支付。在一个实现中，在可计费实体获得访问之前，根据预定的容差参数仔细检查计费信息。在另一实施方案中，多个计费实体向主机系统提供计费信息，随后检查计费信息并将其合并为可被可计费实体远程访问的合并量。在优选实施方式中，将多个公用事业提供者并入系统并为客户提供计费信息，其可以具有由不同实用程序服务的多个不同的，地理上分离的站点。计费信息通过由客户发起的访问以电子方式整合并提供。优选地，本发明的系统和方法结合诸如因特网的多用户计算机网络来实现。

9. 发明授权

US5943656A Methods and systems for computerized bill consolidating, billing and payment authorization, computerized utility bill consolidating, utility billing access and payment and utility provider consolidated billing systems 失效
标题翻译：计算机化帐单合并，计费和付款授权的方法和系统，计算机化公用事业账单合并，公用事业账单访问和支付以及公用事业提供商综合计费系统
公开(公告)号：US5943656A
公开(公告)日：1999-08-24
申请号：US984708
申请日：1997-12-03
申请人： Gerry Crooks , Janna Genzberger , Ed Arnhold , John Battista , Ken Boni , Dave Miller , Mark Feichtner , Larry Kippenhan , Shawn Nanto , Teri Orr , Dan Bowers
发明人： Gerry Crooks , Janna Genzberger , Ed Arnhold , John Battista , Ken Boni , Dave Miller , Mark Feichtner , Larry Kippenhan , Shawn Nanto , Teri Orr , Dan Bowers
IPC分类号： G06Q20/04 , G06Q20/14 , G06Q30/02 , G06Q30/04 , G06Q40/00 , G06Q50/06 , G06F17/60
CPC分类号： G06Q30/04 , G06Q20/04 , G06Q20/14 , G06Q30/0283 , G06Q40/12 , G06Q50/06 , Y10S707/99945 , Y10S707/99948
摘要： Computerized billing and payment authorization methods and systems are described. In one aspect, a host system includes a database in which information associated with a billable entity from which payment is to be received is stored. Billing information is received from a billing entity and is associated with a bill for payment by the billable entity. The billable entity is provided with remote electronic access to the billing information in the host computer and can authorization payment thereof. In one implementation, the billing information is scrutinized in accordance with pre-determined tolerance parameters prior to the billable entity gaining access thereto. In another implementation, a plurality of billing entities provide billing information to the host system, with the billing information being subsequently checked and consolidated into a consolidated amount which can be remotely accessed by the billable entity. In a preferred implementation a plurality of utility providers are incorporated into the system and providing billing information for customers which may have a number of different, geographically-separated sites being serviced by different utilities. The billing information is consolidated and made available electronically through access which is initiated by the customer. Preferably, the systems and methodologies of the invention are implemented in connection with a multi-user computer network such as the Internet.
摘要翻译：描述了计算机化的计费和支付授权方法和系统。一方面，主机系统包括数据库，其中存储有与要从其接收支付的可计费实体相关联的信息。计费信息从计费实体接收，并且与可结算实体的支付账单相关联。可计费实体被提供对主计算机中的计费信息的远程电子访问，并且可以对其进行授权支付。在一个实现中，在可计费实体获得访问之前，根据预定的容差参数仔细检查计费信息。在另一实施方案中，多个计费实体向主机系统提供计费信息，随后检查计费信息并将其合并为可被可计费实体远程访问的合并量。在优选实施方式中，将多个公用事业提供者并入系统并为客户提供计费信息，其可以具有由不同实用程序服务的多个不同的，地理上分离的站点。计费信息通过由客户发起的访问以电子方式整合并提供。优选地，本发明的系统和方法结合诸如因特网的多用户计算机网络来实现。

10. 发明授权

US5930773A Computerized resource accounting methods and systems, computerized utility management methods and systems, multi-user utility management methods and systems, and energy-consumption-based tracking methods and systems 失效
标题翻译：计算机资源会计方法和系统，计算机化公用事业管理方法和系统，多用途公用事业管理方法和系统以及基于能耗的跟踪方法和系统
公开(公告)号：US5930773A
公开(公告)日：1999-07-27
申请号：US992678
申请日：1997-12-17
申请人： Gerry Crooks , Ed Arnhold , John Battista , Ken Boni , Dan Bowers , Mark Feichtner , Blaine French , Janna Genzberger , David D. Holmes , Larry Kippenhan , Dave Miller , Shawn Nanto , Teri Orr , Ed Schlect
发明人： Gerry Crooks , Ed Arnhold , John Battista , Ken Boni , Dan Bowers , Mark Feichtner , Blaine French , Janna Genzberger , David D. Holmes , Larry Kippenhan , Dave Miller , Shawn Nanto , Teri Orr , Ed Schlect
IPC分类号： G06Q10/06 , G06Q20/04 , G06Q20/10 , G06Q20/14 , G06Q30/02 , G06Q30/04 , G06Q30/06 , G06Q40/00 , G06Q50/06 , H02J3/00 , G06F17/60
CPC分类号： G06Q10/06 , G06Q10/06311 , G06Q20/04 , G06Q20/102 , G06Q20/14 , G06Q30/0283 , G06Q30/04 , G06Q30/06 , G06Q40/12 , G06Q50/06 , H02J3/008 , G06Q40/125 , Y04S10/60 , Y04S50/10 , Y04S50/12 , Y04S50/14 , Y10S707/99945 , Y10S707/99948
摘要： Computerized resource accounting methods and systems, and in particular computerized utility resource management methods and systems, multi-user utility resource management methods and systems, and energy-consumption-based tracking methods and systems are described. In one implementation, a host computer includes a processor, an interface device and a database defined therein for maintaining information pertaining to one or more customers of one or more resources. Resource usage information is received into the host computer pertaining to consumption of one or more of the resources by one or more of the customers at one or more customer site. The resource usage information is processed to provide usage-based, computer-viewable data associated with a respective customer's consumption of one or more of the resources. In a preferred aspect, each customer is provided with computer access to the computer-viewable data through the interface device, wherein the customer can view the data at a location which is remote from the host computer. Preferably, the computer-viewable data comes in the form of a plurality of different graphical reports, including numerical and tabulated reports, which can be selected by a customer. For customers with multiple sites, the viewable data for the various sites can be viewed remotely and in a plurality of different report formats. In a preferred implementation, utility resource usage information, e.g. electricity, gas, water, etc. . . , is tracked, maintained, and made available to facilitate decision making.
摘要翻译：描述了计算机资源会计方法和系统，特别是计算机化的公用事业资源管理方法和系统，多用户实用程序资源管理方法和系统以及基于能量消耗的跟踪方法和系统。在一个实现中，主计算机包括处理器，接口设备和在其中定义的数据库，用于维护与一个或多个资源的一个或多个客户有关的信息。资源使用信息被接收到主计算机中，涉及由一个或多个客户站点中的一个或多个客户消费一个或多个资源。处理资源使用信息以提供与相应客户对一个或多个资源的消费相关联的基于用户的可计算机可见数据。在优选的方面，通过接口设备向每个客户提供对计算机可浏览数据的计算机访问，其中客户可以在远离主计算机的位置处查看数据。优选地，计算机可视数据以多种不同的图形报告的形式出现，包括可以由客户选择的数字和制表报告。对于具有多个站点的客户，可以远程查看各种站点的可查看数据，并以多种不同的报告格式进行查看。在优选实施例中，公用事业资源使用信息，例如，电，气，水等。。，被跟踪，维护和提供，以便于决策。

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