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1. 发明申请

US20050131014A1 Quinolines useful in treating cardiovascular disease 失效
标题翻译：喹啉可用于治疗心血管疾病
公开(公告)号：US20050131014A1
公开(公告)日：2005-06-16
申请号：US11010236
申请日：2004-12-10
申请人： Michael Collini , Robert Singhaus , Baihua Hu , James Jetter , Robert Morris , David Kaufman , Christopher Miller , John Ullrich , Rayomand Unwalla , Jay Wrobel , Elaine Quinet , Ponnal Nambi , Ronald Bernotas , Merle Elloso
发明人： Michael Collini , Robert Singhaus , Baihua Hu , James Jetter , Robert Morris , David Kaufman , Christopher Miller , John Ullrich , Rayomand Unwalla , Jay Wrobel , Elaine Quinet , Ponnal Nambi , Ronald Bernotas , Merle Elloso
IPC分类号： A61K31/47 , A61K31/4709 , C07D215/14 , C07D215/54 , C07D401/04 , C07D401/06 , C07D401/12 , C07D401/14 , C07D405/04 , C07D405/06 , C07D405/12 , C07D409/04 , C07D409/06 , C07D409/12 , C07D413/04 , C07D413/06 , C07D417/12 , C07D41/02
CPC分类号： C07D401/04 , C07D215/14 , C07D215/54 , C07D401/06 , C07D401/12 , C07D401/14 , C07D405/04 , C07D405/06 , C07D405/12 , C07D409/04 , C07D409/06 , C07D409/12 , C07D413/04 , C07D413/06 , C07D417/12
摘要： This invention provides compounds of formula I that are useful in the treatment or inhibition of LXR mediated diseases.
摘要翻译：本发明提供可用于治疗或抑制LXR介导的疾病的式I化合物。

2. 发明申请

US20060074128A1 Substituted 2-phenyl benzofurans as estrogenic agents 审中-公开
标题翻译：取代的2-苯基苯并呋喃酮作为雌激素剂
公开(公告)号：US20060074128A1
公开(公告)日：2006-04-06
申请号：US11247361
申请日：2005-10-11
申请人： Christopher Miller , Michael Collini , David Kaufman , Robert Morris , Robert Singhaus , John Ullrich , Heather Harris , James Keith , Leo Albert , Rayomand Unwalla
发明人： Christopher Miller , Michael Collini , David Kaufman , Robert Morris , Robert Singhaus , John Ullrich , Heather Harris , James Keith , Leo Albert , Rayomand Unwalla
IPC分类号： A61K31/343 , C07D307/87
CPC分类号： C07D307/80 , C07D405/06 , C07D413/04
摘要： This invention provides estrogen receptor modulators of formula 1, having the structure wherein R, R′, A, A′, X, Y, and Y are as defined in the specification, or a pharmaceutically acceptable salt thereof.
摘要翻译：本发明提供式1的雌激素受体调节剂，其具有其中R，R'，A，A'，X，Y和Y如说明书中所定义的结构或其药学上可接受的盐。

3. 发明申请

US20050038107A1 Substituted 2-phenyl benzofurans as estrogenic agents 失效
标题翻译：取代的2-苯基苯并呋喃酮作为雌激素剂
公开(公告)号：US20050038107A1
公开(公告)日：2005-02-17
申请号：US10828970
申请日：2004-04-21
申请人： Christopher Miller , Michael Collini , David Kaufman , Robert Morris , Robert Singhaus , John Ullrich , Heather Harris , James Keith , Leo Albert , Rayomand Unwalla
发明人： Christopher Miller , Michael Collini , David Kaufman , Robert Morris , Robert Singhaus , John Ullrich , Heather Harris , James Keith , Leo Albert , Rayomand Unwalla
IPC分类号： A61P5/00 , C07D307/80 , C07D405/06 , C07D413/04 , A61K31/343 , C07D307/78
CPC分类号： C07D307/80 , C07D405/06 , C07D413/04
摘要： This invention provides estrogen receptor modulators of formula I, having the structure wherein R, R′, A, A′, X, Y, and Y are as defined in the specification, or a pharmaceutically acceptable salt thereof.
摘要翻译：本发明提供式I的雌激素受体调节剂，其具有其中R，R'，A，A'，X，Y和Y如说明书中所定义的结构或其药学上可接受的盐。

4. 发明申请

US20140377026A1 METHOD AND APPARATUS DOR HOLDING KEYS DURING THE CUTTING PROCESS 审中-公开
标题翻译：在切割过程中的方法和装置夹具
公开(公告)号：US20140377026A1
公开(公告)日：2014-12-25
申请号：US14477280
申请日：2014-09-04
申请人： Richard W. Ryai, SR. , David Kaufman
发明人： Richard W. Ryai, SR. , David Kaufman
IPC分类号： B23C3/35
CPC分类号： B23C3/355 , B23C3/35 , Y10T409/300952 , Y10T409/309016
摘要： A method and apparatus for holding a key or key blank while copying a key including at least one holder having an opening configured to at least partially enclose at least two sides of a keyway is provided herein. The opening of the holder includes at least one longitudinal groove or one longitudinal protrusion configured to mate with at least one longitudinal protrusion or longitudinal groove of the keyway. A user slides a first holder over the keyway of a key blank, and a second holder over a keyway of a key to be copied and places the holders into clamping jaws of a key cutting machine prior to copying a key.
摘要翻译：本文提供了一种用于在复制包括具有至少部分地包围键槽的至少两侧的开口的至少一个保持器的钥匙的同时保持钥匙或钥匙坯件的方法和装置。保持器的开口包括至少一个纵向凹槽或一个纵向突起，其构造成与键槽的至少一个纵向突起或纵向凹槽配合。使用者将第一保持器滑过钥匙坯件的键槽，将第二支架滑过要复制的钥匙的键槽，并且在复制钥匙之前将支架放置在钥匙切割机的夹爪中。

5. 发明申请

US20060171911A1 Diiodomethyl-p-tolylsulfone as a particulate dispersion in a liquid solvent in combination with an anti-dandruff active 审中-公开
标题翻译：作为液体溶剂中的颗粒分散体的二碘甲基 - 对甲苯基砜与抗头皮屑活性物质
公开(公告)号：US20060171911A1
公开(公告)日：2006-08-03
申请号：US11341052
申请日：2006-01-27
申请人： James Schwartz , David Warnke , David Kaufman , Gregory Tormos , Theodore Verbrugge
发明人： James Schwartz , David Warnke , David Kaufman , Gregory Tormos , Theodore Verbrugge
IPC分类号： A61K33/32 , A61K33/04 , A61K36/00 , A61K31/555
CPC分类号： A61Q5/006 , A61K8/27 , A61K8/46 , A61K8/4933 , A61K8/4946 , A61K31/555 , A61K33/04 , A61K33/32 , A61K45/06 , A61K2300/00
摘要： The present invention relates to a composition comprising an effective amount of diiodomethyl-p-tolylsulfone wherein the diiodomethyl-p-tolylsulfone is present as a particulate dispersion, an effective amount of a surfactant, and an effective amount of an antidandruff active.
摘要翻译：本发明涉及包含有效量的二碘甲基对甲苯砜的组合物，其中二碘甲基对甲苯砜作为颗粒分散体存在，有效量的表面活性剂和有效量的去头皮屑活性物质。

6. 发明申请

US20120014762A1 METHOD AND APPARATUS FOR HOLDING KEYS DURING THE CUTTING PROCESS 有权
标题翻译：用于在切割过程中保持啮合的方法和装置
公开(公告)号：US20120014762A1
公开(公告)日：2012-01-19
申请号：US13179250
申请日：2011-07-08
申请人： Richard W. Ryai, SR. , David Kaufman
发明人： Richard W. Ryai, SR. , David Kaufman
IPC分类号： B23C3/35
CPC分类号： B23C3/355 , B23C3/35 , Y10T409/300952 , Y10T409/309016
摘要： A method and apparatus for holding a key or key blank while copying a key including at least one holder having an opening configured to at least partially enclose at least two sides of a keyway is provided herein. The opening of the holder includes at least one longitudinal groove or one longitudinal protrusion configured to mate with at least one longitudinal protrusion or longitudinal groove of the keyway. A user slides a first holder over the keyway of a key blank, and a second holder over a keyway of a key to be copied and places the holders into clamping jaws of a key cutting machine prior to copying a key.
摘要翻译：本文提供了一种用于在复制包括具有至少部分地包围键槽的至少两侧的开口的至少一个保持器的钥匙的同时保持钥匙或钥匙坯件的方法和装置。保持器的开口包括至少一个纵向凹槽或一个纵向突起，其构造成与键槽的至少一个纵向突起或纵向凹槽配合。使用者将第一保持器滑过钥匙坯件的键槽，将第二支架滑过要复制的钥匙的键槽，并且在复制钥匙之前将支架放置在钥匙切割机的夹爪中。

7. 发明申请

US20050118276A1 Coated metal pyrithione particles for treatment of microorganisms 有权
标题翻译：用于处理微生物的包被金属吡啶硫酮颗粒
公开(公告)号：US20050118276A1
公开(公告)日：2005-06-02
申请号：US10952337
申请日：2004-09-28
申请人： Deqing Lei , George Polson , Diana Ciccognani , Kevin DiNicola , Richard Shalvoy , Katherine Roberts , Louis Punto , James Schwartz , David Kaufman
发明人： Deqing Lei , George Polson , Diana Ciccognani , Kevin DiNicola , Richard Shalvoy , Katherine Roberts , Louis Punto , James Schwartz , David Kaufman
IPC分类号： A61K20060101 , A61K9/14 , A61K9/16 , A61K9/50 , A61K31/555 , A61K35/78
CPC分类号： A61Q5/006 , A61K8/11 , A61K8/4933 , A61K31/44 , A61K2800/412
摘要： A composition comprising coated particles of a salt of pyrithione selected from the group consisting of monovalent and polyvalent pyrithione salts, and combinations thereof, partially or fully coated with a lipophilic agent. The composition is characterized by enhanced anti-fungal and anti-dandruff efficacy in shampoos. Also disclosed is a personal care composition, preferably a shampoo, containing a topical carrier and coated particles of a salt of pyrithione selected from the group consisting of monovalent and polyvalent pyrithione salts, and combinations thereof, partially or fully coated with a lipophilic agent.
摘要翻译：一种组合物，其包含选自由一价和多价吡啶硫酮盐组成的一组吡啶硫酮盐的包衣颗粒，及其组合，部分或全部用亲脂剂包被。组合物的特征在于在洗发剂中增强抗真菌和抗头皮屑功效。还公开了一种个人护理组合物，优选洗发剂，其包含局部载体和选自吡啶硫酮盐的包衣颗粒，其选自单价和多价吡啶硫酮盐及其组合，部分或完全涂覆有亲脂剂。

8. 发明授权

US6027507A Leg length gauge for total hip surgery 失效
标题翻译：全长髋关节外科手术长度计
公开(公告)号：US6027507A
公开(公告)日：2000-02-22
申请号：US70237
申请日：1998-04-30
申请人： James M. Anderson , William J. Bose , David Kaufman
发明人： James M. Anderson , William J. Bose , David Kaufman
IPC分类号： A61B5/107 , A61B19/00 , A61F2/32 , A61F2/46 , A61B17/56
CPC分类号： A61F2/4657 , A61B2090/061 , A61B5/107 , A61B5/4528 , A61F2/32 , A61F2002/4658
摘要： A leg length gauge for use during hip joint replacement surgery to insure that the overall length of the patient's leg subsequent to the surgery is substantially the same as it was prior to the surgery. A first pin is inserted into a patient's ilium and a second pin is inserted into the patient's femur. A removable gauge including an adjustably coupled pair of members having pin receiving apertures for receiving the first and second pins is positioned on the pins. One member includes a base portion provided with one of said pin receiving apertures and having an elongated leg extending from the base portion. The other member is provided with the other pin receiving aperture and includes a transverse aperture for receiving the elongated leg. The elongated leg is selectively adjustably secured within the transverse aperture by tightening a thumbscrew. When properly oriented, the first pin extends generally vertically from the ilium, the second pin extends generally vertically from the femur and the elongated leg extends generally horizontally between the base portion and the other member.
摘要翻译：用于髋关节置换手术期间的腿部长度计，以确保手术后患者腿部的总长度与手术前基本相同。将第一针插入患者的髂骨中，将第二针插入患者的股骨。包括可调节地耦合的一对构件的可拆卸的量具具有用于接收第一和第二销的销接收孔定位在销上。一个构件包括设置有所述销接收孔中的一个并具有从基部延伸的细长腿的基部。另一个构件设置有另一个销接收孔，并且包括用于接收细长腿的横向孔。通过拧紧指旋螺钉，细长的腿可选择性地可调节地固定在横向孔内。当适当定向时，第一销大致垂直地从髂骨延伸，第二销大体上垂直于股骨延伸，并且细长腿在基部和另一个构件之间大致水平地延伸。

9. 发明授权

US4982430A Bootstrap channel security arrangement for communication network 失效
标题翻译：通信网络的引导通道安全安排
公开(公告)号：US4982430A
公开(公告)日：1991-01-01
申请号：US726676
申请日：1985-04-24
申请人： William A. Frezza , Richard D. Conover , David Kaufman
发明人： William A. Frezza , Richard D. Conover , David Kaufman
IPC分类号： H04L9/00 , G06F9/445 , G06F11/00 , G06F11/08 , G06F13/00 , G06F15/177 , G06F21/12 , G06F21/14 , H04H20/00 , H04H20/79 , H04H20/91 , H04H60/14 , H04H60/25 , H04L9/06 , H04L9/10 , H04L9/14 , H04L9/16 , H04L12/22 , H04L29/00 , H04L29/06 , H04N7/16 , H04N21/235 , H04N21/435 , H04N21/81
CPC分类号： H04L63/0428 , G06F11/0763 , G06F15/177 , G06F9/4416 , H04L12/22 , H04L63/12 , H04N21/235 , H04N21/435 , H04N21/8166 , G06F11/08
摘要： Apparatus and a method are disclosed to enable on-line modification and upgrading of terminal software in a communication network while maintaining the integrity of communication between a service provider and a subscriber using the network. Software is downloaded on a booter channel on the communication network. A subscriber terminal, coupled to the network initiates a communication with the network to receive downloaded booter data. The downloaded data is stored, and a checksum is computed from at least a portion of the downloaded data. The checksum is tested for validity, and control of the subscriber terminal is released to the downloaded software only if the checksum is valid.
摘要翻译：公开了一种装置和方法，以便能够在通信网络中对终端软件进行在线修改和升级，同时保持服务提供商和使用网络的订户之间的通信的完整性。软件被下载在通信网络上的引导通道上。耦合到网络的订户终端发起与网络的通信以接收下载的引导数据。存储下载的数据，并且根据下载的数据的至少一部分来计算校验和。对校验和进行有效性测试，只有当校验和有效时，才将用户终端的控制释放到下载的软件。

10. 发明申请

US20080097875A1 SYSTEM AND METHOD FOR PROVIDING ABSORBENT PAPER PRODUCTS AND PACKAGING THEREFOR HAVING COORDINATED CONSUMER-SPECIFIED FEATURES 有权
标题翻译：用于提供吸收纸产品的系统和方法以及具有协调消费者特征的包装
公开(公告)号：US20080097875A1
公开(公告)日：2008-04-24
申请号：US11961547
申请日：2007-12-20
申请人： David Kaufman , Timothy McFarland
发明人： David Kaufman , Timothy McFarland
IPC分类号： G06Q30/00
CPC分类号： G06Q30/02 , G06Q30/0613 , G06Q30/0617 , G06Q30/0621 , G06Q30/0633 , G06Q40/04
摘要： Methods and systems by which a consumer may select or specify coordinated features of an absorbent paper product and its packaging, such as a facial tissue or paper towel product, and then receive an absorbent paper product and packaging having the coordinated features selected or specified by the consumer.
摘要翻译：消费者可以通过该方法和系统选择或指定吸收性纸产品及其包装的协调特征，例如面巾纸或纸巾产品，然后接收具有由所述吸收性纸产品选择或指定的协调特征的吸收性纸产品和包装消费者。

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