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1. 发明申请

US20070020660A1 Expression profiles of peripheral blood mononuclear cells for inflammatory bowel diseases 审中-公开
标题翻译：外周血单核细胞对炎症性肠病的表达谱
公开(公告)号：US20070020660A1
公开(公告)日：2007-01-25
申请号：US11448611
申请日：2006-06-06
申请人： Michael Burczynski , Ron Peterson , Natalie Twine , Andrew Strahs , Frederick Immermann , Ullrich Schwertschlag , Monette Cotreau , Andrew Dorner
发明人： Michael Burczynski , Ron Peterson , Natalie Twine , Andrew Strahs , Frederick Immermann , Ullrich Schwertschlag , Monette Cotreau , Andrew Dorner
IPC分类号： C12Q1/68 , C12P19/34
CPC分类号： C12Q1/6883 , C12Q2600/136 , C12Q2600/158
摘要： The present invention is directed to the identification of PBMC- and IBD-associated biomarkers that may be used to diagnose inflammatory bowel disease, and optionally, distinguish between PBMCs isolated from a patient with Crohn's disease and PBMCs isolated from a patient with ulcerative colitis. The present invention is further directed to methods of screening, including high throughput methods of screening, for regulatory agents capable of regulating the activity of PBMC- and IBD-associated biomarkers. Provided are compositions of PBMC- and IBD-associated biomarkers, including regulatory agents of at least one PBMC- and IBD-associated biomarker for methods of diagnosis, prognosis, therapeutic intervention and prevention of an inflammatory bowel disease, e.g., Crohn's disease and ulcerative colitis. Moreover, the present invention is also directed to methods that can be used to assess the efficacy of test compounds and therapies in the treatment inflammatory bowel disease, i.e., Crohn's disease or ulcerative colitis.
摘要翻译：本发明涉及可用于诊断炎症性肠病的PBMC-和IBD相关生物标志物的鉴定，以及任选地区分从患有克罗恩病的患者和从具有溃疡性结肠炎的患者分离的PBMC中分离的PBMC。本发明还涉及对能够调节PBMC-和IBD相关生物标志物的活性的调节剂的筛选方法，包括筛选的高通量方法。提供了PBMC-和IBD相关生物标志物的组合物，包括用于诊断，预后，治疗性干预和预防炎症性肠病的方法的至少一种PBMC和IBD相关生物标志物的调节剂，例如克罗恩病和溃疡性结肠炎。此外，本发明还涉及可用于评估测试化合物和疗法在治疗炎性肠病，即克罗恩病或溃疡性结肠炎中的功效的方法。

2. 发明申请

US20060048912A1 Die-casting systems and methods 失效
标题翻译：压铸系统和方法
公开(公告)号：US20060048912A1
公开(公告)日：2006-03-09
申请号：US10936422
申请日：2004-09-08
申请人： Ron Peterson , Mark Maas
发明人： Ron Peterson , Mark Maas
IPC分类号： B22D17/08 , B22D27/04 , B22D17/26
CPC分类号： B22D17/22 , B22D17/2218 , B22D17/26
摘要： The invention provides die casting systems and methods. A die casting system has two body portions, each having a die insert. A die-insert rack that holds the die inserts thereon and is used for positioning the die inserts between the two body portions is also provided. The rack includes a die-insert-ejection system for pushing the die inserts into the respective body portions. Each body portion may include a plurality of cooling inserts connected in parallel between inlet and outlet channels of a corresponding body portion. One body portion may include a plurality of alignment blocks protruding therefrom, while the other body portion may have a plurality of recesses for respectively receiving the alignment blocks. Each recess may have adjustable sidewalls for adjusting alignment between the body portions.
摘要翻译：本发明提供压铸系统和方法。压铸系统具有两个主体部分，每个部分具有模具插入件。还提供了一种模具插入架，其将模具插入件保持在其上并且用于在两个主体部分之间定位模具插入件。机架包括用于将模具插入件推入相应主体部分的模具插入物排出系统。每个主体部分可以包括在对应的主体部分的入口和出口通道之间并联连接的多个冷却插入件。一个主体部分可以包括从其突出的多个对准块，而另一个主体部分可以具有用于分别接收对准块的多个凹部。每个凹部可以具有用于调节主体部分之间的对准的可调侧壁。

3. 发明申请

US20100291850A1 Variable Volume Air-Flow Exhaust System 审中-公开
标题翻译：可变体积气流排气系统
公开(公告)号：US20100291850A1
公开(公告)日：2010-11-18
申请号：US12773721
申请日：2010-05-04
申请人： Mike Sabbaghian , Brad Cochran , Ron Peterson , Tom Sieber
发明人： Mike Sabbaghian , Brad Cochran , Ron Peterson , Tom Sieber
IPC分类号： B08B15/02
CPC分类号： B08B15/002
摘要： Disclosed is a smart and adaptive laboratory hood or building exhaust air system and related methods of use.
摘要翻译：公开了一种智能和适应性的实验室护罩或建筑物排气系统及相关使用方法。

4. 发明申请

US20130282476A1 SYSTEM AND METHOD FOR DETERMINING CROSS-CHANNEL, REAL-TIME INSIGHTS FOR CAMPAIGN OPTIMIZATION AND MEASURING MARKETING EFFECTIVENESS 审中-公开
标题翻译：用于确定交叉通道的系统和方法，实时优化用于航空优化和测量营销有效性
公开(公告)号：US20130282476A1
公开(公告)日：2013-10-24
申请号：US13449425
申请日：2012-04-18
申请人： Ron Peterson , Ananth Varma
发明人： Ron Peterson , Ananth Varma
IPC分类号： G06Q30/02
CPC分类号： G06Q30/0241
摘要： The present invention provides a method and system for determining insights for mid-campaign optimization of a marketing campaign and measuring true marketing effectiveness. The method and system includes receiving a plurality of advertising data from one or more advertising data collection sources and electronically processing the advertising data to extract advertising data points therefrom. The method and system include accessing a plurality of historical data points from a historical data point storage device and mapping a plurality of relationships between one or more of the advertising data points and/or the historical data points. Thereupon, the method and system provides for determining at least one advertising campaign modification instruction based on the mapped relationships.
摘要翻译：本发明提供了一种用于确定营销活动中期活动优化的见解的方法和系统，并且测量真正的营销效果。所述方法和系统包括从一个或多个广告数据收集源接收多个广告数据，并且电子地处理广告数据以从其中提取广告数据点。该方法和系统包括从历史数据点存储装置访问多个历史数据点，并映射一个或多个广告数据点和/或历史数据点之间的多个关系。因此，该方法和系统提供基于映射的关系来确定至少一个广告活动修改指令。

5. 发明申请

US20070227687A1 DIE-CASTING SYSTEM 审中-公开
标题翻译： DIE铸造系统
公开(公告)号：US20070227687A1
公开(公告)日：2007-10-04
申请号：US11759015
申请日：2007-06-06
申请人： Ron Peterson , Mark Maas
发明人： Ron Peterson , Mark Maas
IPC分类号： B22D17/26
CPC分类号： B22D17/22 , B22D17/2218 , B22D17/26
摘要： The invention provides a die casting system with an external die body having first and second body portions. A die insert is inserted into an opening of each of the first and second body portions.
摘要翻译：本发明提供一种压铸系统，其具有具有第一和第二主体部分的外模体。将模具插入件插入到第一和第二主体部分的每一个的开口中。

6. 发明授权

US07240719B2 Die-casting systems and methods 失效
标题翻译：压铸系统和方法
公开(公告)号：US07240719B2
公开(公告)日：2007-07-10
申请号：US10936422
申请日：2004-09-08
申请人： Ron Peterson , Mark Maas
发明人： Ron Peterson , Mark Maas
IPC分类号： B22D33/04
CPC分类号： B22D17/22 , B22D17/2218 , B22D17/26
摘要： The invention provides die casting systems and methods. A die casting system has two body portions, each having a die insert. A die-insert rack that holds the die inserts thereon and is used for positioning the die inserts between the two body portions is also provided. The rack includes a die-insert-ejection system for pushing the die inserts into the respective body portions. Each body portion may include a plurality of cooling inserts connected in parallel between inlet and outlet channels of a corresponding body portion. One body portion may include a plurality of alignment blocks protruding therefrom, while the other body portion may have a plurality of recesses for respectively receiving the alignment blocks. Each recess may have adjustable sidewalls for adjusting alignment between the body portions.
摘要翻译：本发明提供压铸系统和方法。压铸系统具有两个主体部分，每个部分具有模具插入件。还提供了一种模具插入架，其将模具插入件保持在其上并且用于在两个主体部分之间定位模具插入件。机架包括用于将模具插入件推入相应主体部分的模具插入物排出系统。每个主体部分可以包括在对应的主体部分的入口和出口通道之间并联连接的多个冷却插入件。一个主体部分可以包括从其突出的多个对准块，而另一个主体部分可以具有用于分别接收对准块的多个凹部。每个凹部可以具有用于调节主体部分之间的对准的可调侧壁。

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