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1. 发明申请

US20070041109A1 Darkfield illumination system 审中-公开
标题翻译：暗场照明系统
公开(公告)号：US20070041109A1
公开(公告)日：2007-02-22
申请号：US10554728
申请日：2004-03-10
申请人： Michael Brehm , Ingo Fahlbusch , Heino Heise , Werner Kleinschmidt , Anke Vogelsang
发明人： Michael Brehm , Ingo Fahlbusch , Heino Heise , Werner Kleinschmidt , Anke Vogelsang
IPC分类号： G02B5/08
CPC分类号： G02B21/10 , G02B21/084
摘要： The invention is directed to a darkfield illumination system and is applicable in transmitted light microscopy and in incident light microscopy. A combination with a first, segmented mirror and a second, aspherical mirror is proposed for the purpose of uniform illumination of the large object fields occurring at low magnifications.
摘要翻译：本发明涉及一种暗场照明系统，适用于透射光学显微镜和入射光学显微镜。提出了与第一，分段镜和第二非球面镜的组合，用于均匀照明在低倍率下发生的大物体场。

2. 发明授权

US08115164B2 Calibration device and laser scanning microscope with such a calibration device 有权
标题翻译：校准装置和激光扫描显微镜用这种校准装置
公开(公告)号：US08115164B2
公开(公告)日：2012-02-14
申请号：US12320599
申请日：2009-01-29
申请人： Ralf Netz , Wolfgang Bathe , Joerg Steinert , Werner Kleinschmidt , Ingo Fahlbusch , Michael Brehm
发明人： Ralf Netz , Wolfgang Bathe , Joerg Steinert , Werner Kleinschmidt , Ingo Fahlbusch , Michael Brehm
IPC分类号： G01D18/00
CPC分类号： G02B21/34 , G01M11/0264 , G02B21/002 , G02B27/32
摘要： A calibration device for managing a variety of performance tests and/or calibration tasks in a laser scanning microscope. The calibration device, which has focusing optics and a test structure arranged in the focal plane of the focusing optics, with structural elements detectable in reflected and/or transmitted light aligned to each other in a common mounting, can be switched into the microscope beam path in a laser scanning microscope, so that the pupil of the focusing optics coincides with the objective pupil of the laser scanning microscope or lies in a plane conjugated to it.
摘要翻译：用于在激光扫描显微镜中管理各种性能测试和/或校准任务的校准装置。具有聚焦光学元件和布置在聚焦光学器件的焦平面中的测试结构的校准装置可以被转换成显微镜光束路径，该结构元件可在反射和/或透射的光中可检测到，在共同安装中彼此对准在激光扫描显微镜中，使得聚焦光学元件的瞳孔与激光扫描显微镜的客观瞳孔重合或位于与其共轭的平面中。

3. 发明申请

US20090224174A1 Calibration device and laser scanning microscope with such a calibration device 有权
标题翻译：校准装置和激光扫描显微镜用这种校准装置
公开(公告)号：US20090224174A1
公开(公告)日：2009-09-10
申请号：US12320599
申请日：2009-01-29
申请人： Ralf Netz , Wolfgang Bathe , Joerg Steinert , Werner Kleinschmidt , Ingo Fahlbusch , Michael Brehm
发明人： Ralf Netz , Wolfgang Bathe , Joerg Steinert , Werner Kleinschmidt , Ingo Fahlbusch , Michael Brehm
IPC分类号： G01N21/64 , G02B21/06
CPC分类号： G02B21/34 , G01M11/0264 , G02B21/002 , G02B27/32
摘要： A calibration device for managing a variety of performance tests and/or calibration tasks in a laser scanning microscope. The calibration device, which has focusing optics and a test structure arranged in the focal plane of the focusing optics, with structural elements detectable in reflected and/or transmitted light aligned to each other in a common mounting, can be switched into the microscope beam path in a laser scanning microscope, so that the pupil of the focusing optics coincides with the objective pupil of the laser scanning microscope or lies in a plane conjugated to it.
摘要翻译：用于在激光扫描显微镜中管理各种性能测试和/或校准任务的校准装置。具有聚焦光学元件和布置在聚焦光学器件的焦平面中的测试结构的校准装置可以被转换成显微镜光束路径，该结构元件可在反射和/或透射的光中可检测到，在共同安装中彼此对准在激光扫描显微镜中，使得聚焦光学元件的瞳孔与激光扫描显微镜的客观瞳孔重合或位于与其共轭的平面中。

4. 发明申请

US20080106795A1 Immersion microscope objective 有权
标题翻译：浸液显微镜物镜
公开(公告)号：US20080106795A1
公开(公告)日：2008-05-08
申请号：US11979580
申请日：2007-11-06
申请人： Renhu Shi , Ingo Fahlbusch , Werner Kleinschmidt
发明人： Renhu Shi , Ingo Fahlbusch , Werner Kleinschmidt
IPC分类号： G02B21/02 , G02B9/00
CPC分类号： G02B21/33 , G02B27/0068
摘要： An immersion microscope objective includes a system of several optical lenses or lens groups between which air spaces are provided and an adjusting device for adapting the immersion microscope objective to different immersion mediums for correcting imaging errors when utilizing the immersion microscope objective in connection with a cover glass, which closes off a specimen holder, and/or for correcting longitudinal chromatic aberrations. The adjusting device is configured to change two air spaces and especially the air spaces (A1, A2) are linearly changeable.
摘要翻译：浸没式显微镜物镜包括几个光学透镜或透镜组的系统，在该系统之间设有空气空间;以及调节装置，用于将浸没式显微镜物镜适用于不同的浸渍介质，以便在利用与玻璃罩相关的浸没显微镜物镜时校正成像误差，其封闭样品架，和/或用于校正纵向色差。调整装置被配置为改变两个空气空间，特别是空气空间（A 1，A 2，2）可以线性地改变。

5. 发明申请

US20130027768A1 ATTACHMENT OF OPTICAL MICROSCOPE COMPONENTS 有权
标题翻译：光学显微镜组件的附着
公开(公告)号：US20130027768A1
公开(公告)日：2013-01-31
申请号：US13577246
申请日：2011-02-04
申请人： Ingo Fahlbusch , Werner Kleinschmidt , Heinrich Bunger , Peter Schnüll , Wolfgang Hartje , Georg Herbst
发明人： Ingo Fahlbusch , Werner Kleinschmidt , Heinrich Bunger , Peter Schnüll , Wolfgang Hartje , Georg Herbst
IPC分类号： G02B21/24
CPC分类号： G02B7/14 , G02B21/02
摘要： A device for attaching a first optical microscope component part to a second part includes an annular receptacle attached to the second part and an annual insertion part. The annular insertion part includes outside-conical retaining projections. The receptacle includes a base ring having a retaining collar with an inside cone tapering away from the base ring and in which a lateral opening is formed, through which the insertion part can be inserted in the receptacle such that it is located on a pre-locking position in which the annular openings overlap. The insertion part and the receptacle can be moved by reciprocal rotation from the pre-locking position into a locking position in which the outside-conical retaining projections of the insertion part are seated against the inside cone of the retaining collar and press the insertion part on the base ring, whereby the insertion part is locked to the receptacle.
摘要翻译：用于将第一光学显微镜部件附接到第二部件的装置包括附接到第二部分的环形插座和年度插入部。环形插入部分包括外锥形保持突起。所述容器包括具有保持套环的基座环，所述保持套环具有与所述基座环成锥形的内锥体，并且其中形成有侧向开口，所述插入部件可以通过所述侧孔插入所述插座中，使得其位于预锁定环形开口重叠的位置。插入部分和插座可以通过往复旋转从预锁定位置移动到锁定位置，其中插入部分的外锥形保持突起抵靠保持环的内锥体并将插入部分按压在基座环，由此插入部分被锁定到容器。

6. 发明申请

US20120250148A1 ARRANGEMENT FOR EQUALIZING BINOCULAR VISUAL FIELDS 审中-公开
标题翻译：用于平衡双目视域的布置
公开(公告)号：US20120250148A1
公开(公告)日：2012-10-04
申请号：US13514038
申请日：2010-08-23
申请人： Cornelia Bendlin , Ingo Fahlbusch , Werner Kleinschmidt
发明人： Cornelia Bendlin , Ingo Fahlbusch , Werner Kleinschmidt
IPC分类号： G02B21/20
CPC分类号： G02B21/22 , G02B7/004 , G02B25/001
摘要： An arrangement for equalizing binocular visual fields for microscopes and other optical instruments, with an eyepiece arranged in each beam path, and with diaphragms serving the purpose of visual field adjustment. The diaphragms are fixed or movable in or in immediate proximity to an intermediate image plane in the optical output to the left eye and/or to the right eye. One diaphragm is arranged eccentrically or concentrically in the installation space of at least one eyepiece or in at least one eyepiece support of the corresponding optical instrument provided therefor. Adjusters are present for positioning and/or adjusting the diaphragms.
摘要翻译：用于将用于显微镜和其它光学仪器的双目视野平衡的装置，其中设置在每个光束路径中的目镜，以及用于视场调整目的的膜片。隔膜在左眼和/或右眼的光学输出中固定或移动到中间图像平面中或附近。一个隔膜偏心地或同心地布置在至少一个目镜的安装空间中或在为其设置的相应的光学仪器的至少一个目镜支架中。存在用于定位和/或调节隔膜的调节器。

7. 发明授权

US07782539B2 Immersion microscope objective 有权
标题翻译：浸液显微镜物镜
公开(公告)号：US07782539B2
公开(公告)日：2010-08-24
申请号：US11979580
申请日：2007-11-06
申请人： Renhu Shi , Ingo Fahlbusch , Werner Kleinschmidt
发明人： Renhu Shi , Ingo Fahlbusch , Werner Kleinschmidt
IPC分类号： G02B21/02 , G02B21/00
CPC分类号： G02B21/33 , G02B27/0068
摘要： An immersion microscope objective includes a system of several optical lenses or lens groups between which air spaces are provided and an adjusting device for adapting the immersion microscope objective to different immersion mediums for correcting imaging errors when utilizing the immersion microscope objective in connection with a cover glass, which closes off a specimen holder, and/or for correcting longitudinal chromatic aberrations. The adjusting device is configured to change two air spaces and especially the air spaces (A1, A2) are linearly changeable.
摘要翻译：浸没式显微镜物镜包括几个光学透镜或透镜组的系统，在该系统之间设有空气空间;以及调节装置，用于将浸没式显微镜物镜适用于不同的浸渍介质，以便在利用与玻璃罩相关的浸没显微镜物镜时校正成像误差，其封闭样品架，和/或用于校正纵向色差。调整装置被配置为改变两个空气空间，特别是空气空间（A1，A2）是线性可变的。

8. 发明授权

US09001419B2 Attachment of optical microscope components 有权
标题翻译：光学显微镜部件的安装
公开(公告)号：US09001419B2
公开(公告)日：2015-04-07
申请号：US13577246
申请日：2011-02-04
申请人： Ingo Fahlbusch , Werner Kleinschmidt , Heinrich Bunger , Peter Schnüll , Wolfgang Hartje , Georg Herbst
发明人： Ingo Fahlbusch , Werner Kleinschmidt , Heinrich Bunger , Peter Schnüll , Wolfgang Hartje , Georg Herbst
IPC分类号： G02B21/24 , G02B7/14 , G02B21/02
CPC分类号： G02B7/14 , G02B21/02
摘要： A device for attaching a first optical microscope component part to a second part includes an annular receptacle attached to the second part and an annual insertion part. The annular insertion part includes outside-conical retaining projections. The receptacle includes a base ring having a retaining collar with an inside cone tapering away from the base ring and in which a lateral opening is formed, through which the insertion part can be inserted in the receptacle such that it is located on a pre-locking position in which the annular openings overlap. The insertion part and the receptacle can be moved by reciprocal rotation from the pre-locking position into a locking position in which the outside-conical retaining projections of the insertion part are seated against the inside cone of the retaining collar and press the insertion part on the base ring, whereby the insertion part is locked to the receptacle.
摘要翻译：用于将第一光学显微镜部件附接到第二部件的装置包括附接到第二部分的环形插座和年度插入部。环形插入部分包括外锥形保持突起。所述容器包括具有保持套环的基座环，所述保持套环具有与所述基座环成锥形的内锥体，并且其中形成有侧向开口，所述插入部件可以通过所述侧孔插入所述插座中，使得其位于预锁定环形开口重叠的位置。插入部分和插座可以通过往复旋转从预锁定位置移动到锁定位置，其中插入部分的外锥形保持突起抵靠保持环的内锥体并将插入部分按压在基座环，由此插入部分被锁定到容器。

9. 发明申请

US20080049313A1 ILLUMINATION OPTICS FOR AN OPTICAL OBSERVATION DEVICE 审中-公开
标题翻译：光学观察装置的照明光学
公开(公告)号：US20080049313A1
公开(公告)日：2008-02-28
申请号：US11844441
申请日：2007-08-24
申请人： Michael Brehm , Werner Kleinschmidt , Jan Thirase
发明人： Michael Brehm , Werner Kleinschmidt , Jan Thirase
IPC分类号： G02B21/06
CPC分类号： G02B21/16 , G01N21/648 , G02B2207/113
摘要： The invention is directed to illumination optics for an optical device for observing a sample, particularly for TIRF microscopy (Total Internal Reflection Fluorescence Microscopy), wherein the sample is positioned on the side of a carrier glass remote of the illumination optics and the illumination light exiting from the illumination optics is shaped into an illumination beam bundle which encloses an angle not equal to 90° with the normal to the surface of the carrier glass. According to the invention, the illumination optics of the type mentioned above comprise at least two optically active elements which influence the shape and direction of the illumination beam bundle and which are arranged outside of the detection beam path that guides light coming from the sample to a detector. The optically active elements are preferably constructed as annular lenses and are arranged concentrically around the detection beam path.
摘要翻译：本发明涉及用于观察样品的光学装置的照明光学器件，特别是用于TIRF显微镜（全内反射荧光显微镜）的样品，其中样品位于远离照明光学器件的载体玻璃侧，并且照射光离开从照明光学器件被成形为照射束束，其包围与载体玻璃的表面垂直的不等于90°的角度。根据本发明，上述类型的照明光学器件包括影响照明束束的形状和方向的至少两个光学有源元件，它们被布置在检测光束路径的外部，该光束路径将来自样品的光引导到探测器。光学活性元件优选构造为环形透镜并且围绕检测光束路径同心地布置。

10. 发明申请

US20080024861A1 ARRANGEMENT FOR REGULATING THE TEMPERATURE OF THE SAMPLE SPACE OF A MICROSCOPE 有权
标题翻译：用于调节显微镜样品空间温度的布置
公开(公告)号：US20080024861A1
公开(公告)日：2008-01-31
申请号：US11828617
申请日：2007-07-26
申请人： EUGEN WEHNER , Joerg Schaffer , Werner Kleinschmidt
发明人： EUGEN WEHNER , Joerg Schaffer , Werner Kleinschmidt
IPC分类号： G02B21/26
CPC分类号： G02B21/28 , B01L7/00 , G02B21/30
摘要： The invention is directed to an arrangement for regulating the temperature of the sample space of a microscope, preferably for observing cells (live cell imaging) with an objective turret carrying objectives, a sample holder serving to receive a sample, a heating or cooling insert with an incubator hood for managing the temperature of the sample holder, and an objective heating element or objective cooling element. According to the invention, at least one structural component part which blocks the heating flow or cooling flow is provided between the objective heating element or objective cooling element and the objective turret.
摘要翻译：本发明涉及一种用于调节显微镜样品空间温度的装置，优选用于观察携带物镜的目标转盘（活细胞成像），用于接收样品的样品架，加热或冷却插入物用于管理样品保持器的温度的孵化器罩，以及客观加热元件或目标冷却元件。根据本发明，在目标加热元件或目标冷却元件和物镜转台之间设置有阻挡加热流或冷却流的至少一个结构部件。

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