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1. 发明授权

US10925964B2 Pharmaceutical formulation comprising ciclesonide 有权
公开(公告)号：US10925964B2
公开(公告)日：2021-02-23
申请号：US14132578
申请日：2013-12-18
申请人： Michael Aven , Balazs Albrecht , Benjamin Franzmann , Matthias Hausmann , Janine Lamar , Ingo Lang
发明人： Michael Aven , Balazs Albrecht , Benjamin Franzmann , Matthias Hausmann , Janine Lamar , Ingo Lang
IPC分类号： A61K47/02 , A61K9/00 , A61K9/08 , A61P11/00 , A61K31/58 , A61K47/10
摘要： The invention relates to the field of medicine, in particular to the field of veterinary medicine. The invention relates to a pharmaceutical (medicament) formulation of glucocorticoids, especially ciclesonide or a pharmaceutically acceptable derivative thereof.

2. 发明授权

US06872736B1 Non-aqueous emulsifiable concentrate formulation 有权
标题翻译：非水乳油配方
公开(公告)号：US06872736B1
公开(公告)日：2005-03-29
申请号：US09491708
申请日：2000-01-26
申请人： Michael Aven
发明人： Michael Aven
IPC分类号： A01N43/50 , A01N43/653 , A01N43/90 , A61K31/41 , A61K31/415 , A01N43/64 , A01N43/56
CPC分类号： A61K31/415 , A01N43/653 , A01N43/90 , A61K31/41 , A01N25/30 , A01N25/02 , A01N2300/00
摘要： The invention relates to a non-aqueous, emulsifiable concentrate (EC) formulation for crop protection active compounds which comprises (a1) 50 to 300 g/L of at least one azole derivative having a free hydroxy group or a salt or an adduct thereof, preferably a compound of formula I, wherein, R1 and R2 each independently represent hydrogen atom or an optionally substituted alkyl, alkenyl, alkynyl or alkadienyl group; R3 represents a halogen atom or an optionally substituted alkyl, alkenyl, alkynyl, alkadienyl, alkoxy or aryl group; A represents a nitrogen atom or a CH group; and n represents an integer from 0 to 2; (a2) optionally, 50 to 500 g/L of at least one additional fungicidally active compound; (b) up to 700 g/L of one or more alkoxylates of an aliphatic alcohol, (c) up to 100 g/L of one or more non-ionic dispersants, (d) 10 to 100 g/L of one or more anionic dispersants, (e) 50 to 600 g/L of one or more polar aprotic organic solvents, and (f) 150 to 500 g/L of one or more non-polar organic solvents, any (g) up to 5 g/L of one or more defoamers, and to the use of such a emulsifiable concentrate as a fungicide.
摘要翻译：本发明涉及用于作物保护活性化合物的非水可乳化浓缩物（EC）制剂，其包含（a1）50-300g / L至少一种具有游离羟基的唑衍生物或其盐或其加合物，优选式I的化合物，其中R 1和R 2各自独立地表示氢原子或任选取代的烷基，烯基，炔基或链二烯基; R 3表示卤素原子或任选取代的烷基，烯基，炔基，链二烯基，烷氧基或芳基; A表示氮原子或CH基团; 和（n）表示0至2的整数;（a2）任选地，50至500g / L的至少一种另外的杀真菌活性化合物;（b）至多700g / L脂族醇的一种或多种烷氧基化物，（c ）至多100g / L的一种或多种非离子分散剂，（d）10至100g / L的一种或多种阴离子分散剂，（e）50至600g / L的一种或多种极性非质子有机溶剂，和（f）150至500g / L的一种或多种非极性有机溶剂，任何（g）至多5g / L的一种或多种消泡剂，以及使用这种可乳化浓缩物作为杀真菌剂。

3. 发明申请

US20080041369A1 AEROSOL FORMULATION FOR THE INHALATION OF BETA AGONISTS 审中-公开
标题翻译：吸入激素的气溶胶配方
公开(公告)号：US20080041369A1
公开(公告)日：2008-02-21
申请号：US11839809
申请日：2007-08-16
申请人： Kirsten RADAU , Michael Aven , Rainer Weitzel
发明人： Kirsten RADAU , Michael Aven , Rainer Weitzel
IPC分类号： A61M11/02 , A61K31/535 , A61K31/56 , A61K31/58 , A61M11/00
CPC分类号： A61K9/0078 , A61K47/10 , A61K47/22
摘要： The present invention relates to a propellant-free aerosol formulation which contains one or more compounds of general formula 1, wherein the groups R1, R2, R3 and X− may have the meanings indicated in the claims and in the specification, and two further active substances 2 and 3, for inhalation.
摘要翻译：本发明涉及一种无推进剂的气溶胶制剂，其含有一种或多种通式1的化合物，其中R 1，R 2，R 3，＆lt; / SUP＆gt;和＆lt; / SUP＆gt;可以具有权利要求书和说明书中所示的含义，以及用于吸入的另外两种活性物质2和3。

4. 发明授权

US06894003B2 Enhancement of the activity of carotenoid biosynthesis inhibitor herbicides 失效
标题翻译：增强类胡萝卜素生物合成抑制剂除草剂的活性
公开(公告)号：US06894003B2
公开(公告)日：2005-05-17
申请号：US09865023
申请日：2001-05-24
申请人： Michael Aven , Astrid Brandt , Norbert Nelgen
发明人： Michael Aven , Astrid Brandt , Norbert Nelgen
IPC分类号： A01N43/40 , A01N43/54 , A01N25/08 , A01N25/10 , A01N43/56 , A01N23/40
CPC分类号： A01N43/40 , A01N43/54 , A01N25/12 , A01N25/10 , A01N25/08 , A01N2300/00
摘要： The present invention provides a method for increasing the efficacy of a herbicidal compound of formula I which comprises applying an effective amount of said herbicidal compound directly to the soil in the form of a solid granule or solid powder which contains said herbicidal compound and at least one inert solid carrier. It is another object of this invention to provide solid granular or powder compositions of herbicidal compounds of formula I and at least one inert solid carrier, as well as methods for the use of said compositions in the control of weeds.
摘要翻译：本发明提供了增加式I除草化合物的功效的方法，该方法包括以固体颗粒或固体粉末的形式将有效量的所述除草化合物直接施用于土壤，所述固体颗粒或固体粉末含有所述除草化合物和至少一种惰性固体载体。本发明的另一个目的是提供式I的除草化合物和至少一种惰性固体载体的固体颗粒或粉末组合物，以及使用所述组合物控制杂草的方法。

5. 发明授权

US06383984B1 Aqueous suspension concentrate 有权
标题翻译：水悬浮浓缩物
公开(公告)号：US06383984B1
公开(公告)日：2002-05-07
申请号：US09484563
申请日：2000-01-18
申请人： Michael Aven
发明人： Michael Aven
IPC分类号： A01N5712
CPC分类号： A01N25/04
摘要： The invention relates to an aqueous, concentrated suspension (SC) for crop protection active compounds which comprises (a) 50 to 400 g/L of at least one crop protection active compound; (b) 50 to 500 g/L of at least one adjuvant, which reduces the surface tension in the spray dilution 40 mN/m or less and does not promote the particle growth of the crop protection active compound; (c) at least one surfactant selected from the groups (c1) and (c2): (c1) 5 to 75 g/L of one or more non-ionic dispersants, (c2) 10 to 100 g/L of one or more anionic dispersants, (d) up to 150 g/L of one or more anti-freezing agents, (e) up to 25 g/L of one or more defoamers, (f) up to 25 g/L of one or more preservatives, and (g) 200 to 800 g/L of water, wherein the adjuvant (b) is selected from the group consisting of amine alkoxylates, polyoxyalkylene triglycerides, alkylpolyglycosides, alkenyl succinic anhydride derivatives, polyvinylpyrrolidones, perfluoroalkyl acids derivatives, and mixtures thereof; and to the use of such a concentrate suspension as a pesticide.
摘要翻译：本发明涉及作物保护活性化合物的水性浓缩悬浮液（SC），其包含（a）50至400g / L的至少一种作物保护活性化合物;（b）50至500g / L的至少一种佐剂，其降低喷雾稀释度中的表面张力为40mN / m或更小，并且不促进作物保护活性化合物的颗粒生长;（c）至少一种选自（c1）和（c2）的表面活性剂：（c1）5至75g / L的一种或多种非离子分散剂，（c2）10至100g / L的一种或多种阴离子分散剂，（d）至多150g / L的一种或多种防冻剂试剂，（e）至多25g / L的一种或多种消泡剂，（f）至多25g / L的一种或多种防腐剂，和（g）200至800g / L的水，其中所述佐剂）选自胺烷氧基化物，聚氧化烯甘油三酸酯，烷基聚糖苷，烯基琥珀酸酐衍生物，聚乙烯吡咯烷酮，全氟烷基酸衍生物及其混合物;以及用途o f这样的浓缩物悬浮液作为农药。

6. 发明申请

US20080293710A1 Aerosol formulation for the inhalation of beta-agonists 审中-公开
标题翻译：用于吸入β-激动剂的气雾剂配方
公开(公告)号：US20080293710A1
公开(公告)日：2008-11-27
申请号：US12133066
申请日：2008-06-04
申请人： Michael Aven
发明人： Michael Aven
IPC分类号： A61K31/538
CPC分类号： A61K31/538
摘要： The present invention relates to a propellant-free aerosol formulation which [contains] one or more compounds of general formula 1 wherein the groups R1, R2, R3 and X− may have the meanings given in the claims and specification, for inhalation.
摘要翻译：本发明涉及一种无推进剂的气溶胶制剂，其含有一种或多种通式1的化合物，其中基团R 1，R 2，R 3和X可具有权利要求和说明书中给出的用于吸入的含义。

7. 发明授权

US06387848B1 Non-aqueous concentrated spreading oil composition 失效
标题翻译：非水浓缩散布油组成
公开(公告)号：US06387848B1
公开(公告)日：2002-05-14
申请号：US09716194
申请日：2000-11-17
申请人： Michael Aven , Hideaki Hasui , Masatoshi Motoyoshi
发明人： Michael Aven , Hideaki Hasui , Masatoshi Motoyoshi
IPC分类号： A01N6300
CPC分类号： A01N43/80 , A01N25/02 , A01N43/82 , A01N43/90 , A01N2300/00
摘要： A non-aqueous, stable concentrated single-phase spreading oil (SO) formulation is disclosed. The SO formulation has a compound of formula I as the active ingredient, and at least one plant oil and polar aprotic organic solvent. Optionally, the SO formulation can also have at least one methylated plant oil. The SO formulation is useful as a blasticide in an aquatic environment of rice plants.
摘要翻译：公开了非水稳定的浓缩单相铺展油（SO）制剂。 SO制剂具有式I化合物作为活性成分，以及至少一种植物油和极性非质子有机溶剂。任选地，SO制剂还可以具有至少一种甲基化植物油。 SO制剂可用作水稻植物水生环境中的杀稻瘟菌素。

8. 发明申请

US20110281858A1 AEROSOL FORMULATION FOR THE INHALATION OF BETA AGONISTS 审中-公开
标题翻译：吸入激素的气溶胶配方
公开(公告)号：US20110281858A1
公开(公告)日：2011-11-17
申请号：US13129955
申请日：2009-11-18
申请人： Michael Aven
发明人： Michael Aven
IPC分类号： A61K31/538 , A61M11/00 , A61P11/00
CPC分类号： A61K9/0078 , A61K9/08 , A61K47/186
摘要： The present invention relates to a propellant-free aerosol formulation which [contains] one or more compounds of general formula (1) wherein the groups R1, R2, R3 and X− may have the meanings given in the claims and in the description, for inhalation.
摘要翻译：本发明涉及一种无推进剂的气溶胶制剂，其含有一种或多种通式（1）的化合物，其中基团R 1，R 2，R 3和X可具有权利要求书和说明书中给出的含义，对于吸入

9. 发明授权

US07176209B2 Fungicidal formulation 失效
标题翻译：杀真菌配方
公开(公告)号：US07176209B2
公开(公告)日：2007-02-13
申请号：US10362058
申请日：2001-08-24
申请人： Michael Aven , Ewald Sieverding
发明人： Michael Aven , Ewald Sieverding
IPC分类号： A01N43/90 , A01N43/54
CPC分类号： A01N43/90 , A01N33/08 , A01N31/02 , A01N25/30 , A01N25/08 , A01N25/04 , A01N2300/00
摘要： Adjuvants selectes from mon/ionic water/soluble mixed polyalkoxy-lated aliphatic alcohol surfactants, non ionic water soluble ethoxylated aliphatic alcohol surfactants, amine ethoxylates, and micronized polymeric waxes enhance the efficacy of fungicidal triazolopzrimidines of structural formula I. They can be incorporated into formulations of the fungicidal compounds or be added to spray mixtures (tank mix) as separately formualted additives in order to improve the efficacy and spectrum of these fungicides. This invention also provides fungicidal compositions of said triazolopzrimidines and adjuvants, as well as methods for their use in the control of photopathogenic fungi
摘要翻译：来自单/离子水/可溶性混合聚烷氧基脂肪醇表面活性剂，非离子水溶性乙氧基化脂族醇表面活性剂，胺乙氧基化物和微粉化聚合物蜡的佐剂增强了结构式I的杀真菌三唑并嘧啶的功效。它们可以掺入制剂的杀真菌化合物，或者作为单独形成的添加剂加入到喷雾混合物（罐混合物）中，以提高这些杀真菌剂的功效和光谱。本发明还提供了所述三唑并嘧啶和佐剂的杀真菌组合物，以及它们用于控制光致病真菌的方法

10. 发明授权

US06596775B2 Enhancement of the efficacy of benzoylbenzenes 有权
公开(公告)号：US06596775B2
公开(公告)日：2003-07-22
申请号：US09939740
申请日：2001-08-28
申请人： Michael Aven , Henry Van Tuyl Cotter
发明人： Michael Aven , Henry Van Tuyl Cotter
IPC分类号： A01N3500
CPC分类号： A01N35/04 , A01N25/30 , A01N25/10 , A01N25/02 , A01N2300/00
摘要： The invention relates to method for the enhancement of the activity and/or systemicity of fungicidal compositions containing at least one benzoylbenzene of formula I wherein R1 through R7, m and n are as defined in claim 1, with the aid of one or more adjuvants selected from the group consisting of (a) alkylpolyglycosides, alkenyl succinic acid derivatives, dialkyl sulfosuccinates, polyvinylpyrrolidones, perfluoroalkyl acids derivatives, perfluoro(C3-20)alkyl esters of carboxylic acids, and mixtures thereof; (b) alkoxylated alcohols, amines or acids; (c) water-immiscible polar aprotic solvents; and to the use of such a composition as a fungicide.

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