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1. 发明授权

US06272382B1 Fully implantable cochlear implant system 有权
标题翻译：完全植入式耳蜗植入系统
公开(公告)号：US06272382B1
公开(公告)日：2001-08-07
申请号：US09407826
申请日：1999-09-28
申请人： Michael A. Faltys , Janusz A. Kuzma , Thomas H. R. Lenarz , Alfred E. Mann
发明人： Michael A. Faltys , Janusz A. Kuzma , Thomas H. R. Lenarz , Alfred E. Mann
IPC分类号： A61N136
CPC分类号： A61N1/08 , A61N1/36036 , A61N1/375 , A61N1/3787
摘要： The present invention provides a fully implantable cochlear implant system (FICIS) that allows various configurations of different modules to be combined so as to meet the needs of a particular patient, including very young patients. At least three main modules are used in the FICIS, including (1) a small implantable cochlear stimulator (ICS) module, with permanently attached cochlear electrode array; (2) an implantable speech processor (ISP) module, with integrated microphone and rechargeable battery; and (3) an external module. In one embodiment, the external module may comprise an external speech processor (ESP) module. In another embodiment, the external module may comprise an external battery charger (EBC) module. The ICS and ISP modules are configured to facilitate long time reliable use of the ICS module, e.g., for the lifetime of the patient, and low-risk, relatively easy replacement of the ISP module.
摘要翻译：本发明提供一种完全可植入的人工耳蜗植入系统（FICIS），其允许组合不同模块的各种配置，以便满足特定患者（包括非常年轻的患者）的需要。 FICIS中至少使用三个主要模块，其中包括：（1）一个小型植入式耳蜗刺激器（ICS）模块，具有永久性附加的耳蜗电极阵列; （2）可植入语音处理器（ISP）模块，具有集成麦克风和可充电电池; 和（3）外部模块。在一个实施例中，外部模块可以包括外部语音处理器（ESP）模块。在另一个实施例中，外部模块可以包括外部电池充电器（EBC）模块。 ICS和ISP模块被配置为便于长时间可靠地使用ICS模块，例如在患者的寿命期内，以及低风险，相对容易地更换ISP模块。

2. 发明授权

US06308101B1 Fully implantable cochlear implant system 有权
标题翻译：完全植入式耳蜗植入系统
公开(公告)号：US06308101B1
公开(公告)日：2001-10-23
申请号：US09404966
申请日：1999-09-24
申请人： Michael A. Faltys , Janusz A. Kuzma , John C. Gord
发明人： Michael A. Faltys , Janusz A. Kuzma , John C. Gord
IPC分类号： A61N136
CPC分类号： A61N1/08 , A61N1/36036 , A61N1/375 , A61N1/3787
摘要： A fully implantable cochlear implant system (170) and method includes an implantable cochlear stimulator (ICS) unit (212) that is connected to an implantable speech processor (ISP) unit (210). Both the ISP unit and the ICS unit reside in separate, hermetically-sealed, cases. The ICS unit has a coil (220) permanently connected thereto through which magnetic or inductive coupling may occur with a similar coil located externally during recharging, programming, or externally-controlled modes of operation. The ICS unit further has a cochlear electrode array (114) permanently connected thereto via a first multi-conductor cable (116). The ICS unit 212 also has a second multi-conductor cable (222) attached thereto, which second cable contains no more than five conductors. The second cable is detachably connected to the ISP unit via a connector (224) located on the case of the ISP unit. The ISP unit includes an implantable subcutaneous microphone (218) as an integral part thereof, and further includes ISP circuitry (214) and a replenishable power source (216), e.g., a rechargeable battery.
摘要翻译：完全植入式人工耳蜗植入系统（170）和方法包括连接到可植入语音处理器（ISP）单元（210）的可植入人工耳蜗刺激器（ICS）单元（212）。 ISP单元和ICS单元均位于单独的密封的情况下。 ICS单元具有永久连接到其上的线圈（220），通过该线圈可以在再充电，编程或外部控制的操作模式期间与位于外部的类似线圈发生磁耦合或电感耦合。 ICS单元还具有经由第一多导体电缆（116）永久地连接到其上的耳蜗电极阵列（114）。 ICS单元212还具有附接到其上的第二多导体电缆（222），该第二电缆包含不超过五个导体。第二电缆通过位于ISP单元壳体上的连接器（224）可拆卸地连接到ISP单元。 ISP单元包括可植入式皮下麦克风（218）作为其整体部分，并且还包括ISP电路（214）和可补充电源（216），例如可再充电电池。

3. 发明授权

US07054691B1 Partitioned implantable system 有权
标题翻译：分区植入系统
公开(公告)号：US07054691B1
公开(公告)日：2006-05-30
申请号：US10346482
申请日：2003-01-17
申请人： Janusz A. Kuzma , Michael A. Faltys
发明人： Janusz A. Kuzma , Michael A. Faltys
IPC分类号： A61N1/00
CPC分类号： H04R25/606 , H04R2225/67 , H04R2410/00
摘要： An implantable system includes a plurality of implantable devices that are detachably coupled to each other. Each implantable device of the system includes: (1) an hermetically-sealed case housing electronic components; (2) feedthru terminals mounted to a wall of the hermetically-sealed case adapted to allow electrical contact from a location outside the hermetically-sealed case with the electronic components housed inside the hermetically-sealed case; (3) a coil external to the hermetically-sealed case attached to the feedthru terminals; (4) a flexible molding bonded to the hermetically-sealed case, and wherein the coil is embedded within or otherwise attached to the flexible molding; and (5) engagement means for engaging the flexible molding with a flexible molding of another implantable device of the implantable system. Such engagement means also aligns the coils of the implantable devices that are thus engaged with the engaging means to allow electromagnetic coupling to occur between the aligned coils. In one embodiment, the engaging means includes a hole formed in the flexible molding of a first implantable device and a knob portion formed in the flexible molding of a second implantable device, wherein the knob portion is sized to fit within the hole, and wherein when the knob portion is placed within the hole, the coil of the first device is coaxially aligned with the coil of the second implantable device.
摘要翻译：可植入系统包括可拆卸地彼此联接的多个可植入装置。系统的每个可植入装置包括：（1）密封的电子元件壳体; （2）安装在密封壳体的壁上的馈通端子，其适于允许从密封的壳体外部的位置与容纳在密封的壳体内的电子部件电接触; （3）安装在馈通端子上的气密密封外壳外部的线圈; （4）柔性模制件，其结合到所述密封的壳体上，并且其中所述线圈嵌入所述柔性模制件中或以其他方式附接到所述柔性模制件; 和（5）接合装置，用于将柔性模制件与可植入系统的另一可植入装置的柔性模制件接合。这种接合装置还使由此与接合装置接合的可植入装置的线圈对齐，以允许在排列的线圈之间发生电磁耦合。在一个实施例中，接合装置包括形成在第一可植入装置的柔性模制件中的孔和形成在第二可植入装置的柔性模制件中的把手部分，其中按钮部分的尺寸适于装配在孔内，旋钮部分放置在孔内，第一装置的线圈与第二可植入装置的线圈同轴对准。

4. 发明授权

US6067474A Implantable device with improved battery recharging and powering configuration 失效
标题翻译：具有改进的电池充电和供电配置的可植入设备
公开(公告)号：US6067474A
公开(公告)日：2000-05-23
申请号：US126615
申请日：1998-07-31
申请人： Joseph H. Schulman , Robert Dan Dell , Alfred E. Mann , Michael A. Faltys
发明人： Joseph H. Schulman , Robert Dan Dell , Alfred E. Mann , Michael A. Faltys
IPC分类号： A61F2/02 , A61F2/18 , A61F11/00 , A61N1/08 , A61N1/36 , A61N1/375 , A61N1/378 , H01M2/10 , H01M4/02 , H01M6/10 , H01M10/04 , H01M10/34 , H01M10/46 , H02J7/00 , H02J7/02 , H02J17/00 , A61N1/34
CPC分类号： A61N1/08 , A61N1/36032 , A61N1/375 , A61N1/3787 , H01M10/0436 , H01M10/46 , H01M4/02 , H02J7/025 , H01M10/345 , H01M2/1022 , H01M2/1066 , H01M2004/025 , H01M6/10
摘要： An implantable system, such as a neural stimulator or a cochlear implant system, includes a rechargeable battery configuration having improved recharging and lifetime characteristics. The battery is housed within the implant's case and has first and second electrode plates. Each electrode plate has a plurality of slits that extend across a substantial portion of the plate's surface area. The slits in the electrode plates reduce the magnitude of eddy currents induced in the plates by external ac magnetic fields allowing faster battery recharging times. Alternatively, the electrode plates are wrapped in a spiral configuration such that, in the plane of the spiral, the electrode plates have a small cross-sectional area and no closed current loops. Additionally, the implant device may be housed in a case formed of a high-resistivity material and a circuit included in the implant device is configured to avoid large current loops that would result in eddy current heating. As a backup option, the circuitry of the implant device may optionally be powered from an external battery that inductively couples energy to the same coil that is used to charge the internal battery. In one embodiment, the implantable system is partitioned into first and second implantable cases, each having electrical circuitry therein, and only one having a rechargeable power source therein, facilitating its subsequent replacement for repair or upgrading purposes. The two cases are coupled together when the system is in use. Coupling is achieved either magnetically and/or with a detachable electrical cable. In one embodiment, power is transferred from one implant case to the other using a 3-phase transmission scheme.
摘要翻译：诸如神经刺激器或人工耳蜗植入系统的可植入系统包括具有改善的再充电和寿命特性的可再充电电池配置。电池容纳在植入物壳体内并具有第一和第二电极板。每个电极板具有延伸穿过板的表面区域的大部分的多个狭缝。电极板中的狭缝通过外部交流磁场减小板中感应的涡流的大小，从而允许更快的电池充电时间。或者，电极板被卷绕成螺旋构造，使得在螺旋的平面中，电极板具有小的横截面积并且没有闭合电流环路。另外，植入装置可以容纳在由高电阻率材料形成的壳体中，并且包括在植入装置中的电路被配置为避免将导致涡流加热的大电流环路。作为备用选项，植入装置的电路可以可选地由外部电池供电，外部电池将能量耦合到用于对内部电池充电的相同线圈。在一个实施例中，可植入系统被划分成第一和第二可植入壳体，每个壳体具有电路，并且只有一个在其中具有可再充电的电源，便于其随后的修理或升级目的的更换。当系统使用时，这两种情况耦合在一起。通过磁性和/或可拆卸电缆实现耦合。在一个实施例中，使用3相传输方案将功率从一个植入壳体传送到另一个。

5. 发明授权

US09668068B2 Beamforming microphone system 有权
公开(公告)号：US09668068B2
公开(公告)日：2017-05-30
申请号：US13172980
申请日：2011-06-30
申请人： Michael A. Faltys , Abhijit Kulkarni , Scott A. Crawford
发明人： Michael A. Faltys , Abhijit Kulkarni , Scott A. Crawford
IPC分类号： H04R25/00
CPC分类号： H04R25/407 , H04R25/606
摘要： A system and method for generating a beamforming signal is disclosed. A beam forming signal is generated by disposing a first microphone and a second microphone in horizontal coplanar alignment. The first and second microphones are used to detect a known signal to generate a first response and a second response. The first response is processed along a first signal path communicatively linked to the first microphone, and the second response is processed along a second signal path communicatively linked to the second microphone. The first and second responses are matched, and the matched responses are combined to generate the beamforming signal on a combined signal path.

6. 发明授权

US08996116B2 Modulation of the cholinergic anti-inflammatory pathway to treat pain or addiction 有权
标题翻译：调节胆碱能消炎途径治疗疼痛或成瘾
公开(公告)号：US08996116B2
公开(公告)日：2015-03-31
申请号：US12917197
申请日：2010-11-01
申请人： Michael A. Faltys , Jacob A. Levine
发明人： Michael A. Faltys , Jacob A. Levine
IPC分类号： A61N1/36 , A61N1/05
CPC分类号： A61N1/36053 , A61N1/0551 , A61N1/36071
摘要： Methods and devices for the treatment of chronic pain by modulation of the cholinergic anti-inflammatory pathway. In particular, the methods and systems described herein may be used to enhance chronic pain therapies such as spinal cord stimulation (SCS). Thus, the present invention describes devices and methods for modulation of the cytokine pathway by stimulation of the neuronal cholinergic anti-inflammatory pathway (NCAP) to enhance the treatment of chronic pain by SCS. The use of NCAP in conjunction with SCS may potentiate the effects of SCS and/or prevent the desensitization of the patient to SCS.
摘要翻译：通过调节胆碱能消炎途径治疗慢性疼痛的方法和装置。特别地，本文描述的方法和系统可用于增强慢性疼痛疗法，例如脊髓刺激（SCS）。因此，本发明描述了通过刺激神经元胆碱能抗炎通路（NCAP）来调节细胞因子途径以增强SCS治疗慢性疼痛的装置和方法。使用NCAP与SCS联合可以增强SCS的作用和/或预防患者对SCS的脱敏。

7. 发明申请

US20110054569A1 PRESCRIPTION PAD FOR TREATMENT OF INFLAMMATORY DISORDERS 审中-公开
标题翻译：用于治疗炎症性疾病的治疗垫
公开(公告)号：US20110054569A1
公开(公告)日：2011-03-03
申请号：US12874171
申请日：2010-09-01
申请人： Ralph J. ZITNIK , Michael A. Faltys
发明人： Ralph J. ZITNIK , Michael A. Faltys
IPC分类号： A61N1/08 , A61N1/36
CPC分类号： A61N1/08 , A61N1/372 , A61N1/37247
摘要： Described herein are devices, including interface modules or prescription pads, and systems including these devices and methods of using them, for treating inflammation or inflammatory disorders, and particularly for interfacing with a user desiring to prescribe treatment of an inflammatory disorder using an implanted stimulator.
摘要翻译：本文描述的是包括界面模块或处方垫的装置，以及包括这些装置的系统和使用它们的方法，用于治疗炎症或炎症性疾病的装置，特别是与期望使用植入的刺激器开放治疗炎性病症的用户接口的装置。

8. 发明申请

US20100125304A1 DEVICES AND METHODS FOR OPTIMIZING ELECTRODE PLACEMENT FOR ANTI-INFLAMATORY STIMULATION 有权
标题翻译：用于优化用于抗炎刺激的电极放置的装置和方法
公开(公告)号：US20100125304A1
公开(公告)日：2010-05-20
申请号：US12620413
申请日：2009-11-17
申请人： Michael A. Faltys
发明人： Michael A. Faltys
IPC分类号： A61N1/08
CPC分类号： A61N1/36135 , A61N1/36053 , A61N1/36132
摘要： Described herein are methods, devices and system for selecting an optimum position of a stimulation electrode, and particularly methods, devices and systems for optimizing the position of a stimulation electrode for stimulating the inflammatory reflex and thereby inhibiting inflammation. The methods, devices and systems described herein may generally include the analysis of one or more artifact modalities arising after the application of a stimulation pulse. One or more of these artifact modalities (e.g., EMG, ECG, etc.) may be detected and used to generate a comparable indicator of the fitness of the position of the electrode relative to a target, such as a portion of the inflammatory reflex like the vagus nerve.
摘要翻译：这里描述了用于选择刺激电极的最佳位置的方法，装置和系统，特别是用于优化刺激电极的位置以刺激炎症反射从而抑制炎症的方法，装置和系统。本文描述的方法，装置和系统通常可以包括在施加刺激脉冲之后产生的一个或多个伪影模态的分析。可以检测这些工件模态（例如，EMG，ECG等）中的一种或多种，并用于产生电极相对于靶的适应度的可比指示，例如炎症反射的一部分，例如迷走神经。

9. 发明授权

US07561920B2 Electric and acoustic stimulation fitting systems and methods 有权
标题翻译：电声刺激配件系统和方法
公开(公告)号：US07561920B2
公开(公告)日：2009-07-14
申请号：US11097611
申请日：2005-03-31
申请人： Michael A. Faltys , Philip A. Segel , Edward H. Overstreet , William Vanbrooks Harrison
发明人： Michael A. Faltys , Philip A. Segel , Edward H. Overstreet , William Vanbrooks Harrison
IPC分类号： A61N1/18
CPC分类号： H04R25/70 , A61N1/36036
摘要： Methods and systems for modifying the parameters of at least one hearing device for a patient with residual hearing provide needed orchestration of acoustic and electric stimulation of patients wearing such devices.
摘要翻译：用于修改具有残留听力的患者的至少一个听力装置的参数的方法和系统为佩戴这种装置的患者提供对声学和电刺激的所需编排。

10. 发明授权

US07450994B1 Estimating flap thickness for cochlear implants 有权
标题翻译：估计耳蜗植入物的瓣厚度
公开(公告)号：US07450994B1
公开(公告)日：2008-11-11
申请号：US11016604
申请日：2004-12-16
申请人： Lakshmi Narayan Mishra , Michael A. Faltys
发明人： Lakshmi Narayan Mishra , Michael A. Faltys
IPC分类号： A61N1/00
CPC分类号： A61B5/442 , A61N1/0541 , A61N1/08 , A61N1/36036
摘要： A flap thickness measurement system includes a reference cochlear stimulation system. The reference cochlear stimulation system includes a sound processor, a transmitter that transmits a telemetric signal, and a cochlear stimulator having a receiver that receives the telemetric signal and transmits a signal back to the transmitter. The system further includes one or more flap simulators having one or more known thicknesses that is positioned between the transmitter and receiver. Also included is a microprocessor that receives and processes data representative of tank voltage from the reference cochlear stimulation system.
摘要翻译：皮瓣厚度测量系统包括参考耳蜗刺激系统。参考耳蜗刺激系统包括声音处理器，发送遥测信号的发射器和具有接收遥测信号并将信号发送回发射机的耳蜗刺激器。该系统还包括具有一个或多个已知厚度的一个或多个折翼模拟器，其位于发射器和接收器之间。还包括微处理器，其接收并处理来自参考耳蜗刺激系统的代表罐电压的数据。

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