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1. 发明授权

US09597067B2 Packaged antimicrobial medical device and method of preparing same 有权
公开(公告)号：US09597067B2
公开(公告)日：2017-03-21
申请号：US12415600
申请日：2009-03-31
申请人： Mehmet Reyhan , Robert Cerwin
发明人： Mehmet Reyhan , Robert Cerwin
IPC分类号： A61B17/04 , A61B17/06 , A61L17/00
CPC分类号： A61B17/04 , A61B17/06114 , A61B17/06166 , A61B50/00 , A61B2050/3005 , A61L17/005
摘要： A method of making a packaged antimicrobial suture. The method includes the steps of providing a containment compartment molded from a polymeric resin comprising a polymeric material and an antimicrobial agent, positioning a suture within the containment compartment, the suture comprising one or more surfaces; covering the containment compartment having the suture in an outer package cover having an inner surface, and subjecting the outer package, the containment compartment and the suture to time, temperature and pressure conditions sufficient to vapor transfer an effective amount of the antimicrobial agent from the containment compartment to the suture, while retaining an effective amount of the antimicrobial agent on the containment compartment, thereby substantially inhibiting bacterial colonization on the suture and the containment compartment. A packaged antimicrobial suture is also provided.

2. 发明申请

US20120199502A1 METHOD OF PREPARING A PACKAGED ANTIMICROBIAL MEDICAL DEVICE 审中-公开
标题翻译：制备包装的抗微生物药物装置的方法
公开(公告)号：US20120199502A1
公开(公告)日：2012-08-09
申请号：US13449184
申请日：2012-04-17
申请人： Howard Scalzo , Jerome A. Fischer , Stephen Rothenburger , Robert Cerwin , James R. McDivitt
发明人： Howard Scalzo , Jerome A. Fischer , Stephen Rothenburger , Robert Cerwin , James R. McDivitt
IPC分类号： A61B17/06 , B65B55/02
CPC分类号： A61B17/06114 , A61B17/06166 , A61B50/00 , A61B2017/00889 , A61L17/005 , A61L2300/202 , A61L2300/404 , A61L2300/606
摘要： A method of making a packaged antimicrobial suture comprising the steps of providing a containment compartment that is substantially free of an antimicrobial agent; positioning a suture within the containment compartment, said suture comprising one or more surfaces having an antimicrobial agent disposed thereon, said antimicrobial agent being selected from the group consisting of halogenated hydroxyl ethers, acyloxydiphenyl ethers, and combinations thereof; placing the containment compartment having the suture in an outer package; and subjecting the outer package, the containment compartment and the suture to time, temperature and pressure conditions sufficient to transfer an effective amount of the antimicrobial agent from the suture to the containment compartment, while retaining an effective amount of said antimicrobial agent on the suture, thereby substantially inhibiting bacterial colonization on the suture and the containment compartment.
摘要翻译：一种制备包装的抗微生物缝合线的方法，包括以下步骤：提供基本上不含抗微生物剂的容纳隔室; 将缝合线定位在容纳隔室内，所述缝合线包括一个或多个表面，其上设置有抗微生物剂，所述抗微生物剂选自卤代羟基醚，酰氧基二苯醚及其组合; 将具有缝合线的容纳隔室放置在外包装中; 以及使外包装，容纳隔室和缝合线经受足以将有效量的抗微生物剂从缝线转移到容纳隔室的时间，温度和压力条件，同时将有效量的所述抗微生物剂保留在缝合线上，从而基本上抑制缝合线和容纳隔室上的细菌定植。

3. 发明申请

US20060091034A1 Method of preparing an antimicrobial packaged medical device 有权
标题翻译：制备抗微生物包装医疗器械的方法
公开(公告)号：US20060091034A1
公开(公告)日：2006-05-04
申请号：US11301364
申请日：2005-12-13
申请人： Howard Scalzo , Jerome Fischer , Stephen Rothenburger , Robert Cerwin , James McDivitt
发明人： Howard Scalzo , Jerome Fischer , Stephen Rothenburger , Robert Cerwin , James McDivitt
IPC分类号： A61B19/02
CPC分类号： A61L17/005 , A61B17/06114 , A61B17/06166 , A61B50/00 , A61L2300/202 , A61L2300/404
摘要： A method for making an antimicrobial suture comprising the steps of positioning an antimicrobial agent source within a package comprising an inner surface, said antimicrobial agent being selected from the group consisting of halogenated hydroxyl ethers, acyloxydiphenyl ethers, and combinations thereof; positioning a medical device within the package; and subjecting the package, the antimicrobial agent source and the medical device to time, temperature and pressure conditions sufficient to vapor transfer an effective amount of the antimicrobial agent from the antimicrobial agent source to the medical device, thereby substantially inhibiting bacterial colonization on the medical device. Alternatively, the packaged medical device is produced according to the steps of positioning a medical device within a package; exposing the package having the medical device to an antimicrobial agent source; and subjecting the package having the medical device and the antimicrobial agent source to time, temperature and pressure conditions sufficient to transfer an effective amount of the antimicrobial agent from the antimicrobial agent source to the medical device within the package, thereby substantially inhibiting bacterial colonization on the medical device.
摘要翻译：一种用于制备抗微生物缝合线的方法，包括以下步骤：将抗微生物剂源定位在包含内表面的包装中，所述抗微生物剂选自卤代羟基醚，酰氧基二苯醚及其组合; 将医疗设备定位在包装内; 以及使所述包装，所述抗微生物剂源和所述医疗装置经受足以将有效量的所述抗微生物剂从所述抗微生物剂来源蒸发转移到所述医疗装置的时间，温度和压力条件，从而基本上抑制所述医疗装置上的细菌定植。或者，根据将医疗装置定位在包装内的步骤来制造包装的医疗装置; 将具有医疗装置的包装暴露于抗微生物剂源; 以及将具有医疗装置和抗微生物剂源的包装经受足以将有效量的抗微生物剂从抗微生物剂源转移到包装内的医疗装置的时间，温度和压力条件，从而基本上抑制细菌定植医疗装置。

4. 发明授权

US5788062A Suture dispenser 失效
标题翻译：缝合机
公开(公告)号：US5788062A
公开(公告)日：1998-08-04
申请号：US604200
申请日：1996-02-21
申请人： Robert Cerwin , Marvin Alpern , Yufei Huang , Emil Richard Skula
发明人： Robert Cerwin , Marvin Alpern , Yufei Huang , Emil Richard Skula
IPC分类号： A61B17/06 , A61B19/02 , B65B63/06
CPC分类号： A61B17/06133 , B65B63/06 , A61B2017/06142 , A61B2017/06147 , A61B2050/002 , A61B2050/006 , A61B2050/0084
摘要： Suture dispensers for retaining armed sutures are disclosed. The dispenser disclosed is comprised of two flat panels of material that each have a central opening. A needle park is provided so that the needle is visible in and accessible though the central openings. In preferred embodiments, the needle park is made of a thin sheet of clear material. Several alternate needle park designs are also disclosed. The two panels are preferably locked together using edge locks in the form of corresponding slits and tabs formed on the panels themselves. In addition to being inexpensive, easy to manufacture and easy to fill, the disclosed dispensers is much thinner than current designs and thus requires less storage and shipping space. Methods of loading dispensers are also disclosed. By winding the suture material in a flat spiral around a set of winding pins, the disclosed dispensers can be easily and accurately filled, yet the resulting coiled suture can be withdrawn via the central openings without twisting or kinking the suture material. In certain embodiments pressure on the central portion of the panels permits winding a spiral without the need for a central winding core. In other embodiments, pins are used to both align the panels and provide a winding guide for the suture material.
摘要翻译：披露了用于保留武装缝线的缝合线分配器。公开的分配器由两个平板材料构成，每个平板均具有中心开口。提供针公园，使得针在中央开口处可见并且可通过。在优选的实施例中，针园由薄的透明材料制成。还公开了几个替代的针园设计。两个面板优选地以形成在面板本身上的相应狭缝和凸片的形式的边缘锁定在一起。除了便宜，易于制造和易于填充之外，所公开的分配器比当前设计薄得多，因此需要更少的存储和运输空间。还公开了装载分配器的方法。通过将缝合材料缠绕在一组缠绕销周围的扁平螺旋中，所公开的分配器可以容易且精确地填充，但是所得到的卷绕的缝合线可以经由中心开口取出，而不会扭曲或扭结缝合材料。在某些实施例中，板的中心部分上的压力允许卷绕螺旋，而不需要中心绕组芯。在其它实施例中，销用于两者对准面板并提供用于缝合材料的卷绕引导件。

5. 发明授权

US08156718B2 Method of preparing a packaged antimicrobial medical device 有权
标题翻译：制备包装的抗微生物医疗器械的方法
公开(公告)号：US08156718B2
公开(公告)日：2012-04-17
申请号：US12417518
申请日：2009-04-02
申请人： Howard Scalzo , Jerome A. Fischer , Stephen Rothenburger , Robert Cerwin , James R. McDivitt
发明人： Howard Scalzo , Jerome A. Fischer , Stephen Rothenburger , Robert Cerwin , James R. McDivitt
IPC分类号： B65B55/02
CPC分类号： A61B17/06114 , A61B17/06166 , A61B50/00 , A61B2017/00889 , A61L17/005 , A61L2300/202 , A61L2300/404 , A61L2300/606
摘要： A method of making a packaged antimicrobial suture comprising the steps of providing a containment compartment that is substantially free of an antimicrobial agent; positioning a suture within the containment compartment, said suture comprising one or more surfaces having an antimicrobial agent disposed thereon, said antimicrobial agent being selected from the group consisting of halogenated hydroxyl ethers, acyloxydiphenyl ethers, and combinations thereof; placing the containment compartment having the suture in an outer package; and subjecting the outer package, the containment compartment and the suture to time, temperature and pressure conditions sufficient to vapor transfer an effective amount of the antimicrobial agent from the suture to the containment compartment, while retaining an effective amount of said antimicrobial agent on the suture, thereby substantially inhibiting bacterial colonization on the suture and the containment compartment.
摘要翻译：一种制备包装的抗微生物缝合线的方法，包括以下步骤：提供基本上不含抗微生物剂的容纳隔室; 将缝合线定位在容纳隔室内，所述缝合线包括一个或多个表面，其上设置有抗微生物剂，所述抗微生物剂选自卤代羟基醚，酰氧基二苯醚及其组合; 将具有缝合线的容纳隔室放置在外包装中; 并且将外包装，容纳隔室和缝合线经受足够的时间，温度和压力条件，以将有效量的抗微生物剂从缝线转移到容纳隔室，同时将有效量的所述抗微生物剂保留在缝合线上从而基本上抑制缝合线和容纳隔室上的细菌定植。

6. 发明授权

US07467710B2 Molded package 有权
标题翻译：成型包装
公开(公告)号：US07467710B2
公开(公告)日：2008-12-23
申请号：US11121804
申请日：2005-05-04
申请人： Robert Cerwin , Clifford Dey , Glynn Clements
发明人： Robert Cerwin , Clifford Dey , Glynn Clements
IPC分类号： A61B17/06
CPC分类号： A61B17/06061 , A61B2050/008 , A61B2090/037
摘要： A package assembly and method for packaging sutures is provided. The package includes a substantially rectangular casing defining an internal area therein and including a container portion having a substantially flat bottom side defined by first, second, third and fourth edges, and first, second, third and fourth sides extending upwardly from the first, second, third and fourth edges respectively, and a lid portion removably secured to a top side of the container portion to thereby form an integral casing. The package further includes a plurality of suture packages each having a substantially planar shape, wherein the plurality of packages are positioned within the internal area of the rectangular casing substantially parallel to one another and substantially perpendicular to the bottom side of the container portion. The third side of the container portion, in a region substantially adjacent to the first side of the container portion, includes a removable breakaway portion wherein removal thereof leaves an opening through which the suture packages can be removed.
摘要翻译：提供了用于包装缝线的包装组件和方法。所述包装件包括在其中限定内部区域的基本上矩形的壳体，并且包括具有由第一，第二，第三和第四边缘限定的基本上平坦的底侧的容器部分，以及从第一，第二和第二边缘向上延伸的第一，第二，第三和第四侧面第三和第四边缘，以及可拆卸地固定到容器部分的顶侧的盖部分，从而形成一体的外壳。该包装还包括多个缝合包装，每个缝合包装件具有基本上平面的形状，其中多个包装件位于矩形外壳的内部区域内，基本上彼此平行并且基本垂直于容器部分的底侧。容器部分的第三侧，在与容器部分的第一侧基本相邻的区域中，包括一个可拆卸的分离部分，其中去除部分离开开口，通过该开口缝合包装件可被移除。

7. 发明申请

US20070227914A1 Suture package 审中-公开
标题翻译：缝合包装
公开(公告)号：US20070227914A1
公开(公告)日：2007-10-04
申请号：US11393503
申请日：2006-03-30
申请人： Robert Cerwin , Clifford Dey
发明人： Robert Cerwin , Clifford Dey
IPC分类号： A61B17/06
CPC分类号： A61B17/06133 , A61B2017/06142
摘要： A suture package having a cover member and base member configured so that, when coupled together, they form a continuous channel therebetween. A dispensing port opening through the cover member is aligned with and provides access into the continuous channel. The package also includes a plurality of sutures extending substantially along the length of and within the channel, with an end region of each suture extending out of the channel through the dispensing port opening to a distal end that is removably secured to the package by the holding device. A pathway followed by each suture from the point at which the suture extends out from the suture channel through the dispensing port opening to the point at which the suture is removably secured to the package by the holding device, changes direction by at least 90 degrees.
摘要翻译：一种具有盖构件和基部构件的缝合包，其构造成使得当联接在一起时，它们在它们之间形成连续的通道。通过盖构件的分配口开口与连续通道对准并且提供进入连续通道。包装还包括基本上沿着通道的长度和内部延伸的多个缝合线，每个缝合线的端部区域通过分配端口开口延伸出通道，该远端通过夹持件可拆卸地固定到包装设备。从缝合线从缝合线通道穿过分配端口开口到缝合线通过保持装置可拆卸地固定到包装的位置处的每个缝合线之后的路径改变方向至少90度。

8. 发明授权

US5392917A Easy open 1-2-3 instrumentation package 失效
标题翻译：容易打开1-2-3仪器包装
公开(公告)号：US5392917A
公开(公告)日：1995-02-28
申请号：US101481
申请日：1993-08-03
申请人： Marvin Alpern , Teresa M. Simons , Robert Cerwin , Robert J. Kalinski , Michael D. O'Toole
发明人： Marvin Alpern , Teresa M. Simons , Robert Cerwin , Robert J. Kalinski , Michael D. O'Toole
IPC分类号： A61B17/00 , A61B17/06 , A61B17/068 , A61B17/072 , A61B17/115 , A61B17/128 , A61B19/02 , A61B19/08 , A61F15/00 , A61J1/00 , B65D77/20 , B65D1/34
CPC分类号： B65D77/2056 , A61B50/33 , A61B17/00234 , A61B17/06114 , A61B17/072 , A61B17/07207 , A61B17/115 , A61B17/1285 , A61B2017/0688 , A61B2050/002 , A61B2050/0065 , A61B2050/3006 , A61B46/00 , A61F15/001 , A61J1/00 , B65D2577/2091
摘要： A novel surgical instrumentation kit is provided. There is a sterile reloading unit package in this kit. These reloading units or other separate packages may be maintained in their own sterile environment. Further, the ability of the surgeon to transfer from an endoscopic procedure to an open procedure is provided. Finally, there is described a novel package which allows the surgeon to rapidly open the tray and remove from it a surgical drape containing the instrumentation of the above-described kit.
摘要翻译：提供了一种新颖的外科手术器械套件。该套件中有一个无菌的重新装载单元。这些重新装载单元或其他单独的包装可以保持在它们自己的无菌环境中。此外，提供了外科医生从内窥镜手术转移到开放手术的能力。最后，描述了一种新颖的包装，其允许外科医生快速打开托盘并从其中移除含有上述试剂盒的仪器的手术罩。

9. 发明授权

US5356006A Sterile package for surgical devices 失效
标题翻译：外科手术器械的无菌包装
公开(公告)号：US5356006A
公开(公告)日：1994-10-18
申请号：US991602
申请日：1992-12-16
申请人： Marvin Alpern , Robert Cerwin , Michael O'Toole , Teresa M. Simons , Deborah M. Transue
发明人： Marvin Alpern , Robert Cerwin , Michael O'Toole , Teresa M. Simons , Deborah M. Transue
IPC分类号： A61B17/00 , A61B17/06 , A61B17/068 , A61B17/128 , A61B17/28 , A61B17/34 , A61B19/02 , A61J1/00 , B65D5/30 , B65D5/42 , B65D5/66 , B65D33/16 , B65D81/02 , B65D81/28 , B65D83/10
CPC分类号： B65D33/1691 , A61B50/30 , B65D5/302 , B65D5/4279 , B65D5/6661 , B65D81/022 , A61B17/00234 , A61B17/06138 , A61B17/068 , A61B17/1285 , A61B17/29 , A61B17/34 , A61B2017/00362 , A61B2017/0688 , A61B50/36
摘要： A sterile package for endoscopic devices. The package includes a foam member that holds the endoscopic device in a stable position within the package. The package includes at least one sterile overwrap member and one non-sterile overwrap member.
摘要翻译：内窥镜装置的无菌包装。该包装包括将内窥镜装置保持在包装内的稳定位置的泡沫构件。该包装包括至少一个无菌外包装构件和一个非无菌外包装构件。

10. 发明授权

US5325987A Sterile package for surgical devices 失效
标题翻译：外科手术器械的无菌包装
公开(公告)号：US5325987A
公开(公告)日：1994-07-05
申请号：US62265
申请日：1993-05-17
申请人： Marvin Alpern , Robert Cerwin , Michael O'Toole , Teresa M. Simons , Deborah M. Transue
发明人： Marvin Alpern , Robert Cerwin , Michael O'Toole , Teresa M. Simons , Deborah M. Transue
IPC分类号： A61B17/00 , A61B17/06 , A61B17/068 , A61B17/128 , A61B17/28 , A61B17/34 , A61B19/02 , A61J1/00 , B65D5/30 , B65D5/42 , B65D5/66 , B65D33/16 , B65D81/02 , B65D81/28 , B65D90/04
CPC分类号： B65D33/1691 , A61B50/30 , B65D5/302 , B65D5/4279 , B65D5/6661 , B65D81/022 , A61B17/00234 , A61B17/06138 , A61B17/068 , A61B17/1285 , A61B17/29 , A61B17/34 , A61B2017/00362 , A61B2017/0688 , A61B50/36
摘要： A sterile package for endoscopic devices. The package includes a foam member that holds the endoscopic device in a stable position within the package.
摘要翻译：内窥镜装置的无菌包装。该包装包括将内窥镜装置保持在包装内的稳定位置的泡沫构件。

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