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    • 5. 发明申请
    • PROCEDURE FOR NUCLEIC ACID-BASED DIAGNOSTIC DETERMINATION OF BACTERIAL GERM COUNTS AND KIT FOR THIS PURPOSE
    • 基于核酸的诊断方法确定细菌种类和用于本目的的试剂盒
    • US20130324436A1
    • 2013-12-05
    • US13990242
    • 2010-11-30
    • Gabor KissJanos KissTimea KissAmbrusne Sztancsik Katalin KovacsGeorgina Bernath
    • Gabor KissJanos KissTimea KissAmbrusne Sztancsik Katalin KovacsGeorgina Bernath
    • C12Q1/68
    • C12Q1/689C12Q1/686C12Q2600/16C12Q2561/113C12Q2563/107C12Q2565/102
    • Disclosed are procedures and kits for nucleic acid-based molecular diagnostic determination of bacterial germ counts during which procedure evolutionarily conserved genes and genes coding for characteristic pathogenicity markers, favourably microbial enzyme, toxin, special resistance, are detected using real-time PCR amplification method with the application of fluorescent hydrolysis probes. The multiplication of nucleotide chains takes place with oligonucleotides annealing to the structural gene 5′ end region and to the adjacent upstream regulatory promoter-operator region so that the presence of the structural gene is shown along with the adjacent upstream regulatory promoter-operator sequences; the functional nature of the structural gene is simultaneously checked. The result is measured with a genome unit equivalent DNA amount calibrated to the germ number of sample units equivalent to standard procedures. The calibrated determination of bacterial germ counts is favourably based on single copy gene sequences in the genome, like those coding for characteristic pathogenicity markers.
    • 公开了用于基于核酸的分子诊断测定细菌胚细胞计数的程序和试剂盒,在此过程中,使用实时PCR扩增方法检测进化保守基因和编码特征性致病性标志物的基因,有利于微生物酶,毒素,特异性抗性, 应用荧光水解探针。 核苷酸链的增殖是通过对结构基因5'末端区域和相邻的上游调控启动子 - 操纵子区域退火的寡核苷酸进行的,从而显示结构基因的存在以及相邻的上游调控启动子 - 操纵子序列; 同时检查结构基因的功能性质。 结果用基准单位等效DNA量来测量,该DNA量与标准程序相当的样品单位的胚芽数量校准。 根据基因组中的单拷贝基因序列,如编码特征性致病性标记物的那些,校准的细菌菌数的测定是有利的。
    • 7. 发明授权
    • Elastomeric polymer blends and processes for their production
    • 弹性聚合物共混物及其生产方法
    • US08247495B2
    • 2012-08-21
    • US13015364
    • 2011-01-27
    • Rainer KolbJohn W. ChuGabor KissRobert P. Reynolds, Jr.Jean-Roch SchauderThomas T. Sun
    • Rainer KolbJohn W. ChuGabor KissRobert P. Reynolds, Jr.Jean-Roch SchauderThomas T. Sun
    • C08F8/00C08L23/04C08L23/10
    • C08L23/142C08L2205/02C08L2314/06C08L2666/06
    • Elastomeric polymer blends and processes for their production are described. Specifically, the polymer blends comprise a first polymer and a second polymer, where the first polymer comprises from about 70 wt % to about 90 wt % units derived from propylene and from about 10 wt % to about 30 wt % units derived from ethylene and/or a C4-C10 alpha-olefin, and the second polymer comprises from about 88 wt % to about 98 wt % units derived from propylene and from about 2 wt % to about 12 wt % units derived from ethylene and/or a C4-C10 alpha-olefin. The elastomeric polymer blends are further characterized by having two or more of the following properties: an overall propylene content of between about 75 wt % and about 90 wt %, a melting point between about 110° C. and about 145° C., a Vicat softening point greater than about 45° C., a tensile stress at 300% strain of less than about 500 psi (3447 kPa), as determined by a stress strain test according to ASTM D412, or an average maximum force for pellet separation of less than about 10 N in an accelerated storage stability test. The polymer blends are produced in a dual reactor process, in which the first polymer and the second polymer are prepared using differing catalyst systems.
    • 描述了弹性聚合物共混物及其生产方法。 具体地,聚合物共混物包含第一聚合物和第二聚合物,其中第一聚合物包含约70重量%至约90重量%的衍生自丙烯的单元和约10重量%至约30重量%的衍生自乙烯和/ 或C 4 -C 10α-烯烃,并且第二聚合物包含衍生自丙烯的约88重量%至约98重量%的单元和衍生自乙烯和/或C 4 -C 10的约2重量%至约12重量%的单元 α-烯烃。 弹性体聚合物共混物的进一步特征在于具有两种或更多种以下性能:总丙烯含量为约75重量%至约90重量%,熔点为约110℃至约145℃, 维卡软化点大于约45℃,通过根据ASTM D412的应力应变测试确定的小于约500psi(3447kPa)的300%应变下的拉伸应力或丸粒分离的平均最大力 在加速储存稳定性试验中小于约10N。 聚合物共混物在双重反应器方法中制备,其中使用不同的催化剂体系制备第一聚合物和第二聚合物。
    • 9. 发明授权
    • Monomer/solvent separation and recycle process for propylene containing polymers
    • 含丙烯聚合物的单体/溶剂分离和循环过程
    • US08067512B2
    • 2011-11-29
    • US12384401
    • 2009-04-03
    • Gabor KissJames Richardson Lattner
    • Gabor KissJames Richardson Lattner
    • C08F2/00C08F110/06
    • C08F10/06C08F6/001C08F110/06C08F210/06Y02P20/544C08L23/10C08F2/00C08F2/06
    • Monomer/solvent separation and recycle processes for continuous supercritical, solution and advanced solution polymerization processes for propylene-containing polymers and their blends are provided. The advantageous monomer/solvent separation and recycle process includes heating a polymer-lean recycle stream coming from a gravimetric separator positioned downstream of the reactor to form a heated polymer-lean recycle stream, and subsequently combining the heated polymer-lean recycle stream with the one or more homogenous reactor effluent streams to form a heated reactor effluent mixed stream. The heated reactor effluent mixed stream may then be passed through a pressure let-down valve followed and a gravimetric separator, such as to provide for reduced fouling propensity of the polymer-rich phase and sufficient heating of the polymer-rich phase to be able to pass through the remainder of the processing steps to form a propylene based polymer product without additional heat.
    • 提供了用于含丙烯聚合物及其共混物的连续超临界,溶液和高级溶液聚合方法的单体/溶剂分离和再循环方法。 有利的单体/溶剂分离和再循环方法包括加热来自位于反应器下游的重力分离器的贫聚合物再循环流,形成加热的贫聚合物循环流,随后将加热的贫聚合物再循环流与 或更均匀的反应器流出物流以形成加热的反应器流出物混合流。 然后,加热的反应器流出物混合流可以通过压力降压阀和重量分离器,例如提供富聚合物相的减少的结垢倾向,并充分加热富含聚合物的相以能够 通过其余的处理步骤以形成无需额外热量的丙烯基聚合物产品。