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    • 8. 发明授权
    • Method of motion correction in optical coherence tomography imaging
    • 光学相干断层扫描成像中的运动校正方法
    • US07755769B2
    • 2010-07-13
    • US12075477
    • 2008-03-11
    • Matthew J. EverettKeith E. O'Hara
    • Matthew J. EverettKeith E. O'Hara
    • G01B11/02
    • A61B3/102A61B3/0025A61B3/113A61B3/1233A61B5/0059A61B5/0066G01B9/02048G01B9/02077G01B9/02087G01B9/02091G01N21/4795G01N2021/1787
    • An image data set acquired by an optical coherence tomography (OCT) system is corrected for effects due to motion of the sample. A first set of A-scans is acquired within a time short enough to avoid any significant motion of the sample. A second more extensive set of A-scans is acquired over an overlapping region on the sample. Significant sample motion may occur during acquisition of the second set. A-scans from the first set are matched with A-scans from the second set, based on similarity between the longitudinal optical scattering profiles they contain. Such matched pairs of A-scans are likely to correspond to the same region in the sample. Comparison of the OCT scanner coordinates that produced each A-scan in a matching pair, in conjunction with any shift in the longitudinal scattering profiles between the pair of A-scans, reveals the displacement of the sample between acquisition of the first and second A-scans in the pair. Estimates of the sample displacement are used to correct the transverse and longitudinal coordinates of the A-scans in the second set, to form a motion-corrected OCT data set.
    • 通过光学相干断层摄影(OCT)系统获得的图像数据集由于样品的运动而被校正。 在足够短的时间内获取第一组A扫描,以避免样品的任何显着运动。 在样本上的重叠区域获取第二组更广泛的A扫描。 在采集第二组时可能会发生显着的样品运动。 基于其包含的纵向光学散射曲线之间的相似性,来自第一组的A扫描与来自第二组的A扫描匹配。 这样匹配的A扫描对可能对应于样本中的相同区域。 在匹配对中产生每个A扫描的OCT扫描器坐标与一对A-扫描之间的纵向散射分布的任何变化相结合的比较显示样品在第一和第二A- 扫描成对。 使用样本位移的估计来校正第二组中的A扫描的横向和纵向坐标,以形成运动校正的OCT数据集。