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1. 发明申请

US20100296085A1 RAMAN SPECTROMETRY ASSEMBLY 审中-公开
标题翻译：拉曼光谱仪组件
公开(公告)号：US20100296085A1
公开(公告)日：2010-11-25
申请号：US12763778
申请日：2010-04-20
申请人： Masud Azimi , Kevin J. Knopp , Steve Mclaughlin
发明人： Masud Azimi , Kevin J. Knopp , Steve Mclaughlin
IPC分类号： G01J3/44 , G01N21/65
CPC分类号： G01J3/44 , G01J3/02 , G01J3/021 , G01J3/0218 , G01J3/0227 , G01J3/024 , G01J3/0291 , G01N21/65 , G01N2021/656 , G01N2201/08
摘要： A Raman spectrometry assembly includes a Raman spectrometer having a laser light source and a Raman signal analyzer, an interface module comprising a housing which is connectable to and disconnectable from the spectrometer, and a fiber optic assembly which is connectable to and disconnectable from the interface module, the fiber optic assembly including optical fibers and a probe head at a distal end thereof for disposition adjacent a specimen to be tested, the optical fibers extending from the probe head and adapted to extend to the interface module.
摘要翻译：拉曼光谱仪组件包括具有激光光源和拉曼信号分析器的拉曼光谱仪，包括可与光谱仪连接并可与光谱仪分离的外壳的接口模块，以及可与接口模块连接并与其分离的光纤组件，所述光纤组件包括光纤和在其远端处的探针头，用于邻近待测试的样品布置，所述光纤从探头延伸并适于延伸到接口模块。

2. 发明申请

US20090033928A1 Raman spectrometry assembly 有权
标题翻译：拉曼光谱装配
公开(公告)号：US20090033928A1
公开(公告)日：2009-02-05
申请号：US11894887
申请日：2007-08-22
申请人： Masud Azimi , Kevin J. Knopp , Steve McLaughlin
发明人： Masud Azimi , Kevin J. Knopp , Steve McLaughlin
IPC分类号： G01J3/44
CPC分类号： G01J3/44 , G01J3/02 , G01J3/021 , G01J3/0218 , G01J3/0227 , G01J3/024 , G01J3/0291 , G01N21/65 , G01N2021/656 , G01N2201/08
摘要： A Raman spectrometry assembly includes a Raman spectrometer having a laser light source and a Raman signal analyzer, an interface module comprising a housing which is connectable to and disconnectable from the spectrometer, and a fiber optic assembly which is connectable to and disconnectable from the interface module, the fiber optic assembly including optical fibers and a probe head at a distal end thereof for disposition adjacent a specimen to be tested, the optical fibers extending from the probe head and adapted to extend to the interface module.
摘要翻译：拉曼光谱仪组件包括具有激光光源和拉曼信号分析器的拉曼光谱仪，包括可与光谱仪连接并可与光谱仪分离的外壳的接口模块，以及可与接口模块连接并与其分离的光纤组件，所述光纤组件包括光纤和在其远端处的探针头，用于邻近待测试的样品布置，所述光纤从探头延伸并适于延伸到接口模块。

3. 发明授权

US07701571B2 Raman spectrometry assembly 有权
标题翻译：拉曼光谱装配
公开(公告)号：US07701571B2
公开(公告)日：2010-04-20
申请号：US11894887
申请日：2007-08-22
申请人： Masud Azimi , Kevin J. Knopp , Steve McLaughlin
发明人： Masud Azimi , Kevin J. Knopp , Steve McLaughlin
IPC分类号： G01J3/44 , G01N21/65
CPC分类号： G01J3/44 , G01J3/02 , G01J3/021 , G01J3/0218 , G01J3/0227 , G01J3/024 , G01J3/0291 , G01N21/65 , G01N2021/656 , G01N2201/08
摘要： A Raman spectrometry assembly includes a Raman spectrometer having a laser light source and a Raman signal analyzer, an interface module comprising a housing which is connectable to and disconnectable from the spectrometer, and a fiber optic assembly which is connectable to and disconnectable from the interface module, the fiber optic assembly including optical fibers and a probe head at a distal end thereof for disposition adjacent a specimen to be tested, the optical fibers extending from the probe head and adapted to extend to the interface module.
摘要翻译：拉曼光谱仪组件包括具有激光光源和拉曼信号分析器的拉曼光谱仪，包括可与光谱仪连接并可与光谱仪分离的外壳的接口模块，以及可与接口模块连接并与其分离的光纤组件，所述光纤组件包括光纤和在其远端处的探针头，用于邻近待测试的样品布置，所述光纤从探头延伸并适于延伸到接口模块。

4. 发明申请

US20100133437A1 HANDHELD INFRARED AND RAMAN MEASUREMENT DEVICES AND METHODS 有权
标题翻译：手持式红外和拉曼测量装置和方法
公开(公告)号：US20100133437A1
公开(公告)日：2010-06-03
申请号：US12691047
申请日：2010-01-21
申请人： Masud Azimi , Arran Bibby , Christopher D. Brown , Peili Chen , Kevin J. Knopp , Daryoosh Vakhshoori , Peidong Wang
发明人： Masud Azimi , Arran Bibby , Christopher D. Brown , Peili Chen , Kevin J. Knopp , Daryoosh Vakhshoori , Peidong Wang
IPC分类号： G01J3/44 , G01J5/02
CPC分类号： G01N21/552 , G01J3/02 , G01J3/0202 , G01J3/024 , G01J3/0256 , G01J3/0264 , G01J3/0272 , G01J3/0286 , G01J3/0291 , G01J3/4535 , G01N2021/3595
摘要： We disclose apparatus that includes: (a) an enclosure including an aperture; (b) a prism mounted in the enclosure so that a surface of the prism is exposed through the aperture; (c) an optical assembly contained within the enclosure, the optical assembly including a radiation source and a radiation detector, the source being configured to direct radiation towards the prism and the detector being configured to detect radiation from the source reflected from the exposed surface of the prism; and (d) an electronic processor contained within the enclosure, the electronic processor being in communication with the detector. The apparatus can be configured so that, during operation, the electronic processor determines information about a sample placed in contact with the exposed surface of the prism based on radiation reflected from the exposed prism surface while it is in contact with the sample.
摘要翻译：我们公开了包括以下设备：（a）包括孔的外壳; （b）安装在外壳中的棱镜，使得棱镜的表面通过该孔露出; （c）包含在所述外壳内的光学组件，所述光学组件包括辐射源和辐射探测器，所述源被配置成将辐射引向所述棱镜，并且所述检测器被配置为检测来自所述源的反射的源的辐射，棱镜; 以及（d）包含在所述外壳内的电子处理器，所述电子处理器与所述检测器通信。该装置可以被配置为使得在操作期间，电子处理器在与样品接触的同时基于从暴露的棱镜表面反射的辐射来确定关于与棱镜的暴露表面接触的样品的信息。

5. 发明授权

US07675611B2 Handheld infrared and Raman measurement devices and methods 有权
标题翻译：手持式红外和拉曼测量装置及方法
公开(公告)号：US07675611B2
公开(公告)日：2010-03-09
申请号：US11864304
申请日：2007-09-28
申请人： Masud Azimi , Arran Bibby , Christopher D. Brown , Peili Chen , Kevin J. Knopp , Daryoosh Vakhshoori , Peidong Wang
发明人： Masud Azimi , Arran Bibby , Christopher D. Brown , Peili Chen , Kevin J. Knopp , Daryoosh Vakhshoori , Peidong Wang
IPC分类号： G01N21/35 , G01N21/65
CPC分类号： G01N21/552 , G01J3/02 , G01J3/0202 , G01J3/024 , G01J3/0256 , G01J3/0264 , G01J3/0272 , G01J3/0286 , G01J3/0291 , G01J3/4535 , G01N2021/3595
摘要： We disclose apparatus that includes: (a) an enclosure including an aperture; (b) a prism mounted in the enclosure so that a surface of the prism is exposed through the aperture; (c) an optical assembly contained within the enclosure, the optical assembly including a radiation source and a radiation detector, the source being configured to direct radiation towards the prism and the detector being configured to detect radiation from the source reflected from the exposed surface of the prism; and (d) an electronic processor contained within the enclosure, the electronic processor being in communication with the detector. The apparatus can be configured so that, during operation, the electronic processor determines information about a sample placed in contact with the exposed surface of the prism based on radiation reflected from the exposed prism surface while it is in contact with the sample.
摘要翻译：我们公开了包括以下设备：（a）包括孔的外壳; （b）安装在外壳中的棱镜，使得棱镜的表面通过该孔露出; （c）包含在所述外壳内的光学组件，所述光学组件包括辐射源和辐射探测器，所述源被配置成将辐射引向所述棱镜，并且所述检测器被配置为检测来自所述源的反射的来自所述源的辐射，棱镜; 以及（d）包含在所述外壳内的电子处理器，所述电子处理器与所述检测器通信。该装置可以被配置为使得在操作期间，电子处理器在与样品接触的同时基于从暴露的棱镜表面反射的辐射来确定关于与棱镜的暴露表面接触的样品的信息。

6. 发明授权

US07548311B2 Method and apparatus for conducting Raman spectroscopy 有权
标题翻译：用于进行拉曼光谱的方法和装置
公开(公告)号：US07548311B2
公开(公告)日：2009-06-16
申请号：US11475582
申请日：2006-06-27
申请人： Kevin J. Knopp , Peidong Wang , Masud Azimi , Daryoosh Vakhshoori
发明人： Kevin J. Knopp , Peidong Wang , Masud Azimi , Daryoosh Vakhshoori
IPC分类号： G01J3/44
CPC分类号： G01J3/02 , G01J3/0208 , G01J3/0218 , G01J3/0227 , G01J3/0232 , G01J3/0272 , G01J3/0291 , G01J3/44 , G01J2003/1213 , G01N21/65 , G01N2021/656
摘要： A Raman probe assembly comprises: a light source for generating laser excitation light; a camera for capturing an image; a light analyzer for analyzing a Raman signature; and a light path for (i) delivering the laser excitation light from the light source to the specimen so as to produce the Raman signature for the specimen, (ii) capturing an image of the specimen and directing that image to the camera, and (iii) directing the Raman signature of the specimen to the light analyzer. A method includes providing a Raman probe assembly carried by a remote controlled robot; navigating the remote control robot to a position adjacent to a specimen; opening a shutter/wiper disposed adjacent to a window of the Raman analyzer; using a camera to aim the probe body at the specimen; energizing a light source; and analyzing the return light passed to the light analyzer.
摘要翻译：拉曼探针组件包括：用于产生激光激发光的光源; 用于捕获图像的相机; 用于分析拉曼签名的光分析器; 以及用于（i）将激光激发光从光源传送到样本以产生用于样本的拉曼特征的光路，（ii）拍摄样本的图像并将该图像引导到相机，以及（ iii）将样品的拉曼标记引导到光分析仪。一种方法包括提供由遥控机器人携带的拉曼探针组件; 将远程控制机器人导航到与样本相邻的位置; 打开与拉曼分析仪的窗口相邻设置的快门/刮水器; 使用相机将探针主体对准样本; 激励光源; 并分析通过光分析器的返回光。

7. 发明授权

US07420672B2 Method and apparatus for conducting Raman spectroscopy 有权
标题翻译：用于进行拉曼光谱的方法和装置
公开(公告)号：US07420672B2
公开(公告)日：2008-09-02
申请号：US11820706
申请日：2007-06-20
申请人： Peidong Wang , Daryoosh Vakhshoori , Yu Shen , Kevin J. Knopp , Masud Azimi
发明人： Peidong Wang , Daryoosh Vakhshoori , Yu Shen , Kevin J. Knopp , Masud Azimi
IPC分类号： G01J3/44
CPC分类号： G01N21/65 , G01J3/02 , G01J3/0218 , G01J3/0272 , G01J3/0291 , G01J3/44 , G01J2003/1213 , G01N2021/656
摘要： Disclosed herein are Raman probes that include: (a) a first optical fiber for receiving laser excitation light from a light source and transmitting the same; (b) a first filter for receiving light from the first optical fiber and adapted to pass the laser excitation light and to block spurious signals associated with the light; (c) a second filter for receiving light from the first filter and adapted to direct the light toward a specimen; and (d) focusing apparatus for receiving the light from the second filter, focusing the light on the specimen so as to generate the Raman signal, and returning the Raman signal to the second filter. The second filter is further configured so that when the second filter receives the Raman signal from the focusing apparatus, the second filter filters out unwanted laser excitation light before directing the Raman signal to a second optical fiber.
摘要翻译：本文公开了拉曼探针，其包括：（a）第一光纤，用于从光源接收激发激发光并将其传输; （b）第一滤光器，用于接收来自第一光纤的光，并适于通过激光激发光并阻止与光相关联的寄生信号; （c）第二过滤器，用于接收来自第一过滤器的光，并适于将光引向样本; 和（d）用于接收来自第二滤光器的光的聚焦装置，将光聚焦在样本上以产生拉曼信号，并将拉曼信号返回到第二滤光器。第二滤波器进一步配置成使得当第二滤波器从聚焦装置接收拉曼信号时，第二滤波器在将拉曼信号引导到第二光纤之前滤除不期望的激光激发光。

8. 发明授权

US08107069B2 Method and apparatus for conducting Raman spectroscopy 有权
标题翻译：用于进行拉曼光谱的方法和装置
公开(公告)号：US08107069B2
公开(公告)日：2012-01-31
申请号：US12556200
申请日：2009-09-09
申请人： Peidong Wang , Daryoosh Vakhshoori , Yu Shen , Kevin J. Knopp , Masud Azimi
发明人： Peidong Wang , Daryoosh Vakhshoori , Yu Shen , Kevin J. Knopp , Masud Azimi
IPC分类号： G01J3/44
CPC分类号： G01N21/65 , G01J3/02 , G01J3/0218 , G01J3/0272 , G01J3/0291 , G01J3/44 , G01J2003/1213 , G01N2021/656
摘要： The apparatus disclosed herein features: (a) a handheld, portable spectrometer that includes a radiation source configured to direct incident radiation to a sample, a detector configured to receive signal radiation from the sample, and a housing enclosing the radiation source and the detector; (b) an extended member attachable to the housing and having an interior channel to define a path for directing radiation from the source to the sample and for receiving radiation from the sample at the detector; (c) and a vial receptacle configured to hold a different sample and positioned to receive radiation from the source, where the detector is positioned to receive radiation from the different sample and the housing is configured to support the vial receptacle and attach to the extended member at the same time.
摘要翻译：本文公开的装置特征在于：（a）手持式便携式光谱仪，其包括被配置为将入射辐射引导到样品的辐射源，被配置为从样品接收信号辐射的检测器和包围辐射源和检测器的壳体; （b）可附接到壳体并具有内部通道以限定用于将辐射从源引导到样品并用于在检测器处接收来自样品的辐射的路径的延伸构件; （c）和小瓶容器，其被配置为保持不同的样品并定位成接收来自所述源的辐射，其中所述检测器被定位成接收来自所述不同样品的辐射，并且所述壳体被配置为支撑所述小瓶容器并附接到所述延伸构件与此同时。

9. 发明授权

US08081305B2 Preparing samples for optical measurement 有权
标题翻译：准备样品进行光学测量
公开(公告)号：US08081305B2
公开(公告)日：2011-12-20
申请号：US12414111
申请日：2009-03-30
申请人： Masud Azimi , Arran Bibby , Christopher D. Brown , Peili Chen , Kevin J. Knopp , Daryoosh Vakhshoori , Peidong Wang , Stephen McLaughlin
发明人： Masud Azimi , Arran Bibby , Christopher D. Brown , Peili Chen , Kevin J. Knopp , Daryoosh Vakhshoori , Peidong Wang , Stephen McLaughlin
IPC分类号： G01N21/35 , G01N21/65
CPC分类号： G01J3/02 , G01J3/0202 , G01J3/024 , G01J3/0256 , G01J3/0264 , G01J3/0272 , G01J3/0286 , G01J3/0291 , G01J3/4535 , G01N21/552
摘要： We disclose an apparatus comprising: a hand-portable optical analysis unit including an optical interface; and a device configured to receive and releasably engage the hand-portable optical analysis unit. The device comprises: a housing; a sample unit in the housing; and a resilient member configured to bias the sample unit and the hand-portable analysis unit towards each other when the hand-portable optical analysis unit is received in the device to compress a sample disposed between the sample unit and the optical interface of the optical analysis unit. Methods of analyzing samples are also disclosed.
摘要翻译：我们公开了一种装置，包括：手持式光学分析单元，包括光学接口; 以及被配置为接收和可释放地接合手持式光学分析单元的设备。该装置包括：壳体; 壳体中的样品单元; 以及弹性构件，其构造成当所述手持式光学分析单元被接收在所述装置中时，将所述样本单元和所述手持式分析单元朝向彼此偏置，以压缩设置在所述样本单元和所述光学分析的所述光学界面之间的样本单元。还公开了分析样品的方法。

10. 发明授权

US07636157B2 Method and apparatus for conducting Raman spectroscopy 有权
标题翻译：用于进行拉曼光谱的方法和装置
公开(公告)号：US07636157B2
公开(公告)日：2009-12-22
申请号：US11117940
申请日：2005-04-29
申请人： Peidong Wang , Daryoosh Vakhshoori , Yu Shen , Kevin J. Knopp , Masud Azimi
发明人： Peidong Wang , Daryoosh Vakhshoori , Yu Shen , Kevin J. Knopp , Masud Azimi
IPC分类号： G01J3/44
CPC分类号： G01N21/65 , G01J3/02 , G01J3/0218 , G01J3/0272 , G01J3/0291 , G01J3/44 , G01J2003/1213 , G01N2021/656
摘要： Disclosed herein are Raman probes that include: (a) a first optical fiber for receiving laser excitation light from a light source and transmitting the same; (b) a first filter for receiving light from the first optical fiber and adapted to pass the laser excitation light and to block spurious signals associated with the light; (c) a second filter for receiving light from the first filter and adapted to direct the light toward a specimen; and (d) focusing apparatus for receiving the light from the second filter, focusing the light on the specimen so as to generate the Raman signal, and returning the Raman signal to the second filter. The second filter is further configured so that when the second filter receives the Raman signal from the focusing apparatus, the second filter filters out unwanted laser excitation light before directing the Raman signal to a second optical fiber.
摘要翻译：本文公开了拉曼探针，其包括：（a）第一光纤，用于从光源接收激发激发光并将其传输; （b）第一滤光器，用于接收来自第一光纤的光，并适于通过激光激发光并阻止与光相关联的寄生信号; （c）第二过滤器，用于接收来自第一过滤器的光，并适于将光引向样本; 和（d）用于接收来自第二滤光器的光的聚焦装置，将光聚焦在样本上以产生拉曼信号，并将拉曼信号返回到第二滤光器。第二滤波器进一步配置成使得当第二滤波器从聚焦装置接收拉曼信号时，第二滤波器在将拉曼信号引导到第二光纤之前滤除不期望的激光激发光。

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