专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US5541213A Propenoic acid derivatives diazole propenoic acid compounds which have useful pharmaceutical utility 失效
标题翻译：丙烯酸衍生物具有有用的药用效用的二唑丙烯酸化合物
公开(公告)号：US5541213A
公开(公告)日：1996-07-30
申请号：US258634
申请日：1994-06-10
申请人： Masayuki Matsukura , Keizoh Satoh , Naoki Yoneda , Makoto Kaino , Kazutoshi Miyake , Yoshiharu Daiku , Naoya Kishi , Fusayo Yoshida , Kenichi Nomoto , Toshiaki Ogawa , Tadanobu Takamura , Koichi Nose , Mikio Tomimatsu , Masanori Mizuno , Shigeto Negi , Shigeru Souda
发明人： Masayuki Matsukura , Keizoh Satoh , Naoki Yoneda , Makoto Kaino , Kazutoshi Miyake , Yoshiharu Daiku , Naoya Kishi , Fusayo Yoshida , Kenichi Nomoto , Toshiaki Ogawa , Tadanobu Takamura , Koichi Nose , Mikio Tomimatsu , Masanori Mizuno , Shigeto Negi , Shigeru Souda
IPC分类号： C07D213/38 , C07D213/61 , C07D231/12 , C07D233/54 , C07D401/12 , C07D401/14 , C07D405/14 , C07D409/04 , C07D409/14 , A61K31/415 , C07D231/10
CPC分类号： C07D231/12 , C07D213/38 , C07D213/61 , C07D233/64 , C07D401/12 , C07D401/14 , C07D405/14 , C07D409/04 , C07D409/14
摘要： A novel propenoic acid derivative which exhibits adenosine A1 antagonism is defined by the general formula (I): ##STR1## (wherein A represents an aromatic ring; R.sup.1 represents aryl or the like; R.sup.2, R.sup.3 and R.sup.4 each represent hydrogen, lower alkyl or the like; and R.sup.7 and R.sup.8 each represent lower alkyl or the like) or a pharmacologically acceptable salt thereof.
摘要翻译：表现出腺苷A1拮抗作用的新型丙烯酸衍生物由通式（I）定义：其中A表示芳香环; R1表示芳基等; R2，R3和R4各自表示氢，低级烷基或 R 7和R 8各自表示低级烷基等）或其药理学上可接受的盐。

2. 发明授权

US5606073A Diazole-propenoic acid compounds 失效
标题翻译：二唑 - 丙烯酸化合物
公开(公告)号：US5606073A
公开(公告)日：1997-02-25
申请号：US419941
申请日：1995-04-11
申请人： Masayuki Matsukura , Keizoh Satoh , Naoki Yoneda , Makoto Kaino , Kazutoshi Miyake , Yoshiharu Daiku , Naoya Kishi , Fusayo Yoshida , Kenichi Nomoto , Toshiaki Ogawa , Tadanobu Takamura , Koichi Nose , Mikio Tomimatsu , Masanori Mizuno , Shigeto Negi , Shigeru Souda
发明人： Masayuki Matsukura , Keizoh Satoh , Naoki Yoneda , Makoto Kaino , Kazutoshi Miyake , Yoshiharu Daiku , Naoya Kishi , Fusayo Yoshida , Kenichi Nomoto , Toshiaki Ogawa , Tadanobu Takamura , Koichi Nose , Mikio Tomimatsu , Masanori Mizuno , Shigeto Negi , Shigeru Souda
IPC分类号： C07D213/38 , C07D213/61 , C07D231/12 , C07D233/54 , C07D401/12 , C07D401/14 , C07D405/14 , C07D409/04 , C07D409/14
CPC分类号： C07D231/12 , C07D213/38 , C07D213/61 , C07D233/64 , C07D401/12 , C07D401/14 , C07D405/14 , C07D409/04 , C07D409/14
摘要： Propenoic acid derivatives of the formula: ##STR1## where R.sup.15 and R.sup.17 are aryl or heteroalkyl groups and R.sup.16 and R.sup.18 are hydrogen, a lower alkyl or the like are intermediates used to prepare pharmaceutically active diazole propenoic acid compounds.
摘要翻译：下式的丙烯酸衍生物：其中R 15和R 17是芳基或杂烷基，R 16和R 18是氢，低级烷基等是用于制备药物活性二唑丙烯酸的中间体酸化合物。

3. 发明授权

US06218392B1 Fused pyridazine compounds 失效
标题翻译：稠合哒嗪化合物
公开(公告)号：US06218392B1
公开(公告)日：2001-04-17
申请号：US09161946
申请日：1998-09-29
申请人： Nobuhisa Watanabe , Yasuhiro Kabasawa , Yasutaka Takase , Fumihiro Ozaki , Keiji Ishibashi , Kazuki Miyazaki , Masayuki Matsukura , Shigeru Souda , Kazutoshi Miyake , Hiroki Ishihara , Kohtaro Kodama , Hideyuki Adachi
发明人： Nobuhisa Watanabe , Yasuhiro Kabasawa , Yasutaka Takase , Fumihiro Ozaki , Keiji Ishibashi , Kazuki Miyazaki , Masayuki Matsukura , Shigeru Souda , Kazutoshi Miyake , Hiroki Ishihara , Kohtaro Kodama , Hideyuki Adachi
IPC分类号： A61K31502
CPC分类号： C07D231/12 , C07D233/56 , C07D237/34 , C07D249/08 , C07D401/04 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/12 , C07D405/12 , C07D405/14 , C07D471/04
摘要： A fused pyridazine compound represented by the following general formula (I) or a pharmacologically acceptable salt thereof which exhibits an inhibitory activity against cyclic GMP phosphodiesterase (hereinafter referred to as “cGMP-PDE”). The compounds are useful as preventive and therapeutic agents for diseases for which a cGMP-PDE inhibiting action is efficacious, for example, ischemic heart diseases such as angina pectoris, myocardial infarct and chronic and acute cardiac failure, pulmonary hypertension, arteriosclerosis and bronchial asthma.
摘要翻译：由下述通式（I）表示的稠合哒嗪化合物或其对环状GMP磷酸二酯酶具有抑制活性的药理学上可接受的盐（以下称为“cGMP-PDE”），可用作预防和治疗剂 cGMP-PDE抑制作用有效的疾病，例如心绞痛，心肌梗死，慢性和急性心力衰竭，肺动脉高压，动脉硬化和支气管哮喘等缺血性心脏病。

4. 发明授权

US5849741A Fused pyridazine compounds 失效
标题翻译：稠合哒嗪化合物
公开(公告)号：US5849741A
公开(公告)日：1998-12-15
申请号：US619621
申请日：1996-04-09
申请人： Nobuhisa Watanabe , Yasuhiro Kabasawa , Yasutaka Takase , Fumihiro Ozaki , Keiji Ishibashi , Kazuki Miyazaki , Masayuki Matsukura , Shigeru Souda , Kazutoshi Miyake , Hiroki Ishihara , Kohtaro Kodama , Hideyuki Adachi
发明人： Nobuhisa Watanabe , Yasuhiro Kabasawa , Yasutaka Takase , Fumihiro Ozaki , Keiji Ishibashi , Kazuki Miyazaki , Masayuki Matsukura , Shigeru Souda , Kazutoshi Miyake , Hiroki Ishihara , Kohtaro Kodama , Hideyuki Adachi
IPC分类号： C07D237/34 , C07D401/04 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/12 , C07D405/12 , C07D405/14 , C07D471/04 , C07D521/00 , A01K31/50 , C07D237/30
CPC分类号： C07D231/12 , C07D233/56 , C07D237/34 , C07D249/08 , C07D401/04 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/12 , C07D405/12 , C07D405/14 , C07D471/04
摘要： A fused pyridazine compound represented by the following general formula (I) or a pharmacologically acceptable salt thereof which exhibits an inhibitory activity against cyclic GMP phosphodiesterase (hereinafter referred to as "cGMP-PDE"). The compounds are useful as preventive and therapeutic agents for diseases for which a cGMP-PDE inhibiting action is efficacious, for example, ischemic heart diseases such as angina pectoris, myocardial infarct and chronic and acute cardiac failure, pulmonary hypertension, arteriosclerosis and bronchial asthma. ##STR1##
摘要翻译： PCT No.PCT / JP95 / 01575 Sec。 371日期：1996年4月9日 102（e）日期1996年4月9日PCT提交1995年8月8日PCT公布。出版物WO96 / 05176 日期：1996年2月22日由下述通式（I）表示的稠合哒嗪化合物或其对环状GMP磷酸二酯酶具有抑制活性的药理学上可接受的盐（以下称为“cGMP-PDE”）。所述化合物可用作对于cGMP-PDE抑制作用有效的疾病的预防和治疗剂，例如心绞痛，心肌梗塞，慢性和急性心力衰竭，肺动脉高压，动脉硬化和支气管哮喘等缺血性心脏病。（一）

5. 发明授权

US5298518A Biphenylmethane derivative and pharmacological use 失效
标题翻译：联苯甲烷衍生物和药理用途
公开(公告)号：US5298518A
公开(公告)日：1994-03-29
申请号：US846950
申请日：1992-03-06
申请人： Kazutoshi Miyake , Masayuki Matsukura , Naoki Yoneda , Osamu Hiroshima , Nobuyuki Mori , Hiroki Ishihara , Takashi Musha , Toshiyuki Matsuoka , Sachiyuki Hamano , Norio Minami
发明人： Kazutoshi Miyake , Masayuki Matsukura , Naoki Yoneda , Osamu Hiroshima , Nobuyuki Mori , Hiroki Ishihara , Takashi Musha , Toshiyuki Matsuoka , Sachiyuki Hamano , Norio Minami
IPC分类号： C07D235/08 , C07D235/26 , C07D235/28 , C07D403/10 , C07D471/04 , C07D487/04 , A61K31/415 , C07D235/16 , C07D401/10
CPC分类号： C07D403/10 , C07D235/08 , C07D235/26 , C07D235/28 , C07D471/04 , C07D487/04
摘要： The biphenylmethane derivative having the formula (I) is useful to prevent and treat hypertension and cardiac failure. ##STR1## in which R1 is hydrogen, an alkyl, a cycloalkyl, a halogenated alkyl, --S--R7, --SO2--R7, --C.tbd.C--R7 or --(CH2)--OR7, R7 being hydrogen, an alkyl, a cycloalkyl or a halogenated alkyl, p being zero or 1, --A1.dbd.A2--A3.dbd.A4-- is CH.dbd.CH--CH.dbd.CH--, --N.dbd.CH--CH.dbd.CH--, --CH.dbd.N--CH.dbd.CH--, --CH.dbd.CH--N.dbd.CH--, --CH.dbd.CH--CH.dbd.N-- or --CH.dbd.N--CH.dbd.N--, R2 and R3 are each hydrogen, a halogen, a lower alkyl, a lower alkoxy, a carbamoyl or cyano, R4 is hydrogen or a lower alkyl, R5 is 1H-tetrazol-5-yl, carboxyl (--COOH) or a carboxylic ester and R6 is hydrogen, a halogen, hydroxyl or a lower alkoxy, or a pharmacologically acceptable salt thereof.
摘要翻译：具有式（I）的联苯甲烷衍生物可用于预防和治疗高血压和心脏衰竭。（*化学结构*）其中R1是氢，烷基，环烷基，卤代烷基，-S-R7，-SO2-R7，-C（三键）C-R7或 - （CH2）-OR7，R7 是氢，烷基，环烷基或卤代烷基，p为0或1，-A1 = A2-A3 = A4-为CH = CH-CH = CH-，-N = CH-CH = CH-，-CH = N-CH = CH-，-CH = CH-N = CH-，-CH = CH-CH = N-或-CH = N-CH = N-，R2和R3各自为氢，卤素，烷基，低级烷氧基，氨基甲酰基或氰基，R4是氢或低级烷基，R5是1H-四唑-5-基，羧基（-COOH）或羧酸酯，R6是氢，卤素，羟基或低级烷氧基或其药理学上可接受的盐。

6. 发明授权

US5506238A Biphenylmethane derivative and pharmacological use 失效
标题翻译：联苯甲烷衍生物和药理用途
公开(公告)号：US5506238A
公开(公告)日：1996-04-09
申请号：US877113
申请日：1992-05-01
申请人： Kazutoshi Miyake , Masayuki Matsukura , Naoki Yoneda , Osamu Hiroshima , Nobuyuki Mori , Hiroki Ishihara , Takashi Musha , Toshiyuki Matsuoka , Sachiyuki Hamano , Norio Minami
发明人： Kazutoshi Miyake , Masayuki Matsukura , Naoki Yoneda , Osamu Hiroshima , Nobuyuki Mori , Hiroki Ishihara , Takashi Musha , Toshiyuki Matsuoka , Sachiyuki Hamano , Norio Minami
IPC分类号： C07D235/08 , C07D235/26 , C07D235/28 , C07D403/10 , C07D471/04 , C07D487/04 , A61K31/435
CPC分类号： C07D403/10 , C07D235/08 , C07D235/26 , C07D235/28 , C07D471/04 , C07D487/04
摘要： The biphenylmethane derivative having the formula (I) is useful to prevent and treat hypertension and cardiac failure. ##STR1## in which R1 is hydrogen, an alkyl, a cycloalkyl, a halogenated alkyl, --S--R7, --SO2--R7, --C.tbd.C--R7 or --(CH2)p--OR7, R7 being hydrogen, an alkyl, a cycloalkyl or a halogenated alkyl, p being zero or 1, --A1=A2--A3=A4-- is --CH=CH--CH=CH--, --N=CH--CH=CH--, --CH=N--CH=CH--, --CH=CH--N=CH--, --CH=CH--CH=N-- or --CH=N--CH=N--, R2 and R3 are each hydrogen, a halogen, a lower alkyl, a lower alkoxy, a carbamoyl or cyano, R4 is hydrogen or a lower alkyl, R5 is 1H-tetrazol-5-yl, carboxyl (--COOH) or a carboxylic ester and R6 is hydrogen, a halogen, hydroxyl or a lower alkoxy, or a pharmacologically acceptable salt thereof.
摘要翻译：具有式（I）的联苯甲烷衍生物可用于预防和治疗高血压和心脏衰竭。其中R 1是氢，烷基，环烷基，卤代烷基，-S-R 7，-SO 2 -R 7，-C 3位C-R 7或 - （CH 2）p-OR 7，R 7是氢，烷基，环烷基或卤代烷基，p为0或1，-A1 = A2-A3 = A4-为-CH = CH-CH = CH-，-N = CH-CH = CH-，-CH = N-CH = CH-，-CH = CH-N = CH-，-CH = CH-CH = N-或-CH = N-CH = N-，R2和R3各自为氢，卤素，低级烷基，烷氧基，氨基甲酰基或氰基，R4是氢或低级烷基，R5是1H-四唑-5-基，羧基（-COOH）或羧酸酯，R6是氢，卤素，羟基或低级烷氧基，或其药理学上可接受的盐。

7. 发明授权

US5328911A Biphenylmethane derivative and pharmacological use 失效
标题翻译：联苯甲烷衍生物和药理用途
公开(公告)号：US5328911A
公开(公告)日：1994-07-12
申请号：US583025
申请日：1990-09-13
申请人： Kazutoshi Miyake , Masayuki Matsukura , Naoki Yoneda , Osamu Hiroshima , Nobuyuki Mori , Hiroki Ishihara , Takashi Musha , Toshiyuki Matsuoka , Sachiyuki Hamano , Norio Minami
发明人： Kazutoshi Miyake , Masayuki Matsukura , Naoki Yoneda , Osamu Hiroshima , Nobuyuki Mori , Hiroki Ishihara , Takashi Musha , Toshiyuki Matsuoka , Sachiyuki Hamano , Norio Minami
IPC分类号： C07D235/08 , A61K31/00 , A61K31/415 , A61K31/4184 , A61K31/435 , A61K31/44 , A61K31/496 , A61K31/505 , A61P9/00 , A61P9/12 , A61P43/00 , C07D221/02 , C07D235/02 , C07D235/06 , C07D235/10 , C07D235/12 , C07D235/26 , C07D235/28 , C07D403/10 , C07D471/04 , C07D487/04
CPC分类号： C07D403/10 , C07D235/08 , C07D235/26 , C07D235/28 , C07D471/04 , C07D487/04
摘要： The biphenylmethane derivative having the formula (I) is useful to prevent and treat hypertension and cardiac failure. ##STR1## in which R1 is hydrogen, an alkyl, a cycloalkyl, a halogenated alkyl, --S--R7, --SO2--R7, --C.tbd.C--R7 or --(CH2)p--OR7, R7 being hydrogen, an alkyl, a cycloalkyl or a halogenated alkyl, p being zero or 1, --A1.dbd.A2--A3.dbd.A4-- is --CH.dbd.CH--CH.dbd.CH--, --N.dbd.CH--CH.dbd.CH--, --CH.dbd.N--CH.dbd.CH--, --CH.dbd.CH--N.dbd.CH--, --CH.dbd.CH--CH.dbd.N-- or --CH.dbd.N--CH.dbd.N--, R2 and R3 are each hydrogen, a halogen, a lower alkyl, a lower alkoxy, a carbamoyl or cyano, R4 is hydrogen or a lower alkyl, R5 is 1H-tetrazol-5-yl, carboxyl (--COOH) or a carboxylic ester and R6 is hydrogen, a halogen, hydroxyl or a lower alkoxy, or a pharmacologically acceptable salt thereof.
摘要翻译：具有式（I）的联苯甲烷衍生物可用于预防和治疗高血压和心脏衰竭。其中R 1是氢，烷基，环烷基，卤代烷基，-S-R 7，-SO 2 -R 7，-C 3位C-R 7或 - （CH 2）p-OR 7，R 7是氢，烷基，环烷基或卤代烷基，p为0或1，-A1 = A2-A3 = A4-为-CH = CH-CH = CH-，-N = CH-CH = CH-，-CH = N-CH = CH-，-CH = CH-N = CH-，-CH = CH-CH = N-或-CH = N-CH = N-，R2和R3各自为氢，卤素，低级烷基，烷氧基，氨基甲酰基或氰基，R4是氢或低级烷基，R5是1H-四唑-5-基，羧基（-COOH）或羧酸酯，R6是氢，卤素，羟基或低级烷氧基，或其药理学上可接受的盐。

8. 发明授权

US08153662B2 Heterocycles substituted pyridine derivatives and antifungal agent containing thereof 有权
标题翻译：杂环取代的吡啶衍生物和含有它的抗真菌剂
公开(公告)号：US08153662B2
公开(公告)日：2012-04-10
申请号：US12704643
申请日：2010-02-12
申请人： Keigo Tanaka , Satoshi Inoue , Norio Murai , Masayuki Matsukura , Kazutaka Nakamoto , Shuji Shirotori , Shinya Abe
发明人： Keigo Tanaka , Satoshi Inoue , Norio Murai , Masayuki Matsukura , Kazutaka Nakamoto , Shuji Shirotori , Shinya Abe
IPC分类号： A61K31/42 , A61K31/443 , C07D413/14
CPC分类号： A01N43/56 , A01N43/80 , C07D401/04 , C07D401/14 , C07D413/04 , C07D413/14 , C07D417/14
摘要： An object of the present invention is to provide an antifungal agent which has excellent antifungal effects and is superior in terms of its physical properties, safety and metabolic stability. According to the present invention, there is disclosed a compound represented by the following formula (I), or a salt thereof: wherein R1 represents a hydrogen atom, a halogen atom, an amino group, a C1-6 alkyl group, a C1-6 alkoxy group or a C1-6 alkoxy C1-6 alkyl group; R2 represents a hydrogen atom, a C1-6 alkyl group, an amino group or a di C1-6 alkylamino group; one of X and Y is a nitrogen atom while the other is a nitrogen atom or an oxygen atom; ring A represents a 5- or 6-member heteroaryl ring or a benzene ring which may have a halogen atom, or 1 or 2 C1-6 alkyl groups; Z represents a single bond, a methylene group, an ethylene group, an oxygen atom, a sulfur atom, —CH2O—, —OCH2—, —NH—, —CH2NH—, —NHCH2—, —CH2S—, or —SCH2—; R3 represents a hydrogen atom, a halogen atom, a C1-6 alkyl group, a C3-8 cycloalkyl group, a C6-10 aryl group, a 5- or 6-member heteroaryl group, or 5- or 6-member non-aromatic heterocyclic group which may have 1 or 2 substituents; and R4 represents a hydrogen atom or a halogen atom.
摘要翻译：本发明的目的是提供一种具有优异的抗真菌作用并且在其物理性质，安全性和代谢稳定性方面优异的抗真菌剂。根据本发明，公开了由下式（I）表示的化合物或其盐：其中R1表示氢原子，卤素原子，氨基，C1-6烷基，C1- 6烷氧基或C 1-6烷氧基C 1-6烷基; R2表示氢原子，C1-6烷基，氨基或二C1-6烷基氨基; X和Y之一是氮原子，而另一个是氮原子或氧原子; 环A表示可以具有卤素原子或1或2个C 1-6烷基的5或6元杂芳基环或苯环; Z表示单键，亚甲基，亚乙基，氧原子，硫原子，-CH 2 O - ， - OCH 2 - ， - NH - ， - CH 2 NH - ， - NHCH 2 - ， - CH 2 S-或-SCH 2 - ; R 3表示氢原子，卤素原子，C 1-6烷基，C 3-8环烷基，C 6-10芳基，5-或6-元杂芳基，或5-或6-元非 - 可以具有1或2个取代基的芳族杂环基; R4表示氢原子或卤素原子。

9. 发明授权

US08058444B2 Heterocycle-substituted pyridine derivative's salt or crystal thereof 有权
标题翻译：杂环取代的吡啶衍生物的盐或其结晶
公开(公告)号：US08058444B2
公开(公告)日：2011-11-15
申请号：US12109959
申请日：2008-04-25
申请人： Jun Niijima , Kazutaka Nakamoto , Masayuki Matsukura , Keigo Tanaka , Eiichi Yamamoto , Takuma Minamisono
发明人： Jun Niijima , Kazutaka Nakamoto , Masayuki Matsukura , Keigo Tanaka , Eiichi Yamamoto , Takuma Minamisono
IPC分类号： C07D413/14
CPC分类号： C07D413/14
摘要： There is provided a heterocycle-substituted pyridine derivative's salt or a crystal thereof. The present invention provides an acid addition salt of 3-(3-(4-(pyridin-2-yloxymethyl)-benzyl)-isoxazol-5-yl)-pyridin-2-yl amine or a crystal thereof as well as process for producing the same.
摘要翻译：提供了杂环取代的吡啶衍生物的盐或其结晶。本发明提供3-（3-（4-（吡啶-2-基氧基甲基） - 苄基） - 异恶唑-5-基） - 吡啶-2-基胺或其结晶的酸加成盐以及生产相同。

10. 发明授权

US07612092B2 Nitrogen-containing aromatic derivatives 有权
标题翻译：含氮芳香族衍生物
公开(公告)号：US07612092B2
公开(公告)日：2009-11-03
申请号：US11293785
申请日：2005-12-02
申请人： Yasuhiro Funahashi , Akihiko Tsuruoka , Masayuki Matsukura , Toru Haneda , Yoshio Fukuda , Junichi Kamata , Keiko Takahashi , Tomohiro Matsushima , Kazuki Miyazaki , Ken-ichi Nomoto , Tatsuo Watanabe , Hiroshi Obaishi , Atsumi Yamaguchi , Sachi Suzuki , Katsuji Nakamura , Fusayo Mimura , Yuji Yamamoto , Junji Matsui
发明人： Yasuhiro Funahashi , Akihiko Tsuruoka , Masayuki Matsukura , Toru Haneda , Yoshio Fukuda , Junichi Kamata , Keiko Takahashi , Tomohiro Matsushima , Kazuki Miyazaki , Ken-ichi Nomoto , Tatsuo Watanabe , Hiroshi Obaishi , Atsumi Yamaguchi , Sachi Suzuki , Katsuji Nakamura , Fusayo Mimura , Yuji Yamamoto , Junji Matsui
IPC分类号： A61K31/47
CPC分类号： C07D213/73 , A61K31/4706 , A61K31/4745 , A61K31/517 , A61K31/519 , C07D207/34 , C07D213/26 , C07D213/68 , C07D213/74 , C07D213/75 , C07D213/81 , C07D213/82 , C07D215/18 , C07D215/233 , C07D215/36 , C07D215/38 , C07D215/48 , C07D239/34 , C07D239/42 , C07D239/47 , C07D239/88 , C07D249/04 , C07D261/14 , C07D277/48 , C07D307/68 , C07D319/06 , C07D401/04 , C07D401/12 , C07D401/14 , C07D405/12 , C07D405/14 , C07D409/12 , C07D413/12 , C07D417/12 , C07D417/14 , C07D471/04 , C07D487/04 , C07D491/04 , C07D495/04
摘要： Compounds represented by the following general formula: [wherein Ag is an optionally substituted 5- to 14-membered heterocyclic group, etc.; Xg is —O—, —S—, etc.; Yg is an optionally substituted C6-14 aryl group, an optionally substituted 5- to 14-membered heterocyclic group, etc.; and Tg1 is a group represented by the following general formula: (wherein Eg is a single bond or —N(Rg2)—, Rg1 and Rg2 each independently represent a hydrogen atom, an optionally substituted C1-6 alkyl group, etc. and Zg represents a C1-8 alkyl group, a C3-8 alicyclic hydrocarbon group, a C6-14 aryl group, etc.)], salts thereof or hydrates of the foregoing.
摘要翻译：由以下通式表示的化合物：其中Ag是任选取代的5至14元杂环基等; Xg为-O-，-S-等; Yg是任选取代的C 6-14芳基，任选取代的5至14元杂环基等; Tg1为下列通式表示的基团：（其中Eg为单键或-N（Rg2） - ，Rg1和Rg2各自独立地表示氢原子，可以具有取代基的C1-6烷基等，Zg 表示C 1-8烷基，C 3-8脂环族烃基，C 6-14芳基等）]，其盐或前述的水合物。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式