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1. 发明申请

US20130023839A1 PATCH PREPARATION 有权
标题翻译：配对准备
公开(公告)号：US20130023839A1
公开(公告)日：2013-01-24
申请号：US13542994
申请日：2012-07-06
申请人： Masahiro MITSUSHIMA , Hidetoshi KURODA , Yuji SAEKI , Tomohito TAKITA
发明人： Masahiro MITSUSHIMA , Hidetoshi KURODA , Yuji SAEKI , Tomohito TAKITA
IPC分类号： A61M35/00
CPC分类号： A61K9/7061
摘要： The present invention provides a patch preparation that has an extremely low moisture permeability, has a sufficient ODT effect, is excellent in drug releasability and in anchoring property of its drug-containing pressure-sensitive adhesive layer, and has a preferred patch feeling. The patch preparation of the present invention includes a support; and a pressure-sensitive adhesive layer containing an adherent polymer and a drug on one surface of the support, wherein: the support has a polyester base layer, an inorganic oxide layer, and a polyester nonwoven fabric layer in the stated order; the polyester base layer has a thickness of 1.0 μm to 16 μm; and the pressure-sensitive adhesive layer is laminated on the polyester nonwoven fabric layer.
摘要翻译：本发明提供一种具有极低的透湿性，足够的ODT效果，药物释放性和药物含粘合剂层的锚定性优异的贴片制剂，并且具有优选的贴片感。本发明的贴片制剂包括支持体; 以及在载体的一个表面上含有粘着性聚合物和药物的粘合剂层，其中：所述载体具有所述顺序的聚酯基层，无机氧化物层和聚酯无纺布层; 聚酯基层的厚度为1.0μm〜16μm; 并且将压敏粘合剂层层压在聚酯无纺布层上。

2. 发明申请

US20120251610A1 NICOTINE-CONTAINING PATCH PREPARATION 审中-公开
标题翻译：含尼古丁配制配方
公开(公告)号：US20120251610A1
公开(公告)日：2012-10-04
申请号：US13426333
申请日：2012-03-21
申请人： Kazumi ENOMOTO , Hidetoshi KURODA , Shiro SATODA , Koji NAKAMURA , Tomohito TAKITA
发明人： Kazumi ENOMOTO , Hidetoshi KURODA , Shiro SATODA , Koji NAKAMURA , Tomohito TAKITA
IPC分类号： A61K9/70 , A61P25/34 , A61K31/465
CPC分类号： A61K9/7053 , A61K9/7061 , A61K31/465
摘要： An object of the present invention is to provide a nicotine-containing patch preparation which enables to suppress degradation of nicotine and coloring of the patch preparation. The present invention provides a patch preparation comprising a support and an adhesive layer on its at least one surface, wherein the adhesive layer comprises an adhesive polymer, nicotine and a stabilizer, and the stabilizer is at least one kind selected from the group consisting of butylhydroxyanisole (BHA), propyl gallate (PGA), dibutylhydroxytoluene (BHT) and 2-mercaptobenzimidazole (MBI).
摘要翻译：本发明的目的是提供一种能够抑制尼古丁的降解和贴剂的着色的含尼古丁的贴剂。本发明提供一种贴片制剂，其在其至少一个表面上包含支持体和粘合剂层，其中所述粘合剂层包含粘合剂聚合物，尼古丁和稳定剂，并且所述稳定剂是选自丁基羟基苯甲醚（BHA），没食子酸丙酯（PGA），二丁基羟基甲苯（BHT）和2-巯基苯并咪唑（MBI）。

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