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1. 发明授权

US09480772B2 Gel sheet containing lipid peptide gelator and polymeric compound 有权
标题翻译：含有脂质肽凝胶剂和聚合物的凝胶片
公开(公告)号：US09480772B2
公开(公告)日：2016-11-01
申请号：US13885099
申请日：2011-11-11
申请人： Masahiro Goto , Takayuki Imoto , Tsubasa Kashino , Takehisa Iwama , Nobuhide Miyachi
发明人： Masahiro Goto , Takayuki Imoto , Tsubasa Kashino , Takehisa Iwama , Nobuhide Miyachi
IPC分类号： A61L26/00 , A61K9/00 , A61K9/06 , A61K8/65 , A61K8/73 , A61Q19/00 , A61K8/81 , A61K8/02 , A61K9/70 , A61K8/49 , A61K8/04
CPC分类号： A61L26/0095 , A61K8/0216 , A61K8/042 , A61K8/4946 , A61K8/65 , A61K8/73 , A61K8/8129 , A61K9/0014 , A61K9/06 , A61K9/7015 , A61K2800/10 , A61L26/0052 , A61L26/008 , A61Q19/00
摘要： There is provided a gel sheet that has high biocompatibility and safety, can contain both a hydrophilic medicinal agent and a hydrophobic medicinal agent, and provides an excellent feel in use during the application onto human skin or others. A gel sheet including: a lipid peptide gelator including a low molecular weight lipid peptide having a molecular weight of 1,000 or less or a pharmaceutically usable salt of the lipid peptide; and a polymeric compound, wherein the polymeric compound is included in an amount of more than 1% (w/w) and less than 50% (w/w) with respect to the total mass of the gel sheet.
摘要翻译：提供了具有高生物相容性和安全性的凝胶片，可以含有亲水药剂和疏水性药剂，并且在施用于人皮肤或其它物质时提供了极好的使用感。 1.一种凝胶片，其特征在于，包括：脂质肽凝胶剂，其包含分子量为1000以下的低分子量脂质肽或所述脂质肽的药学上可用的盐; 和聚合物，其中相对于凝胶片的总质量，聚合物的含量大于1％（w / w）且小于50％（w / w）。

2. 发明申请

US20130296761A1 GEL SHEET CONTAINING LIPID PEPTIDE GELATOR AND POLYMERIC COMPOUND 有权
标题翻译：含有脂蛋白凝胶和聚合物的凝胶片
公开(公告)号：US20130296761A1
公开(公告)日：2013-11-07
申请号：US13885099
申请日：2011-11-11
申请人： Masahiro Goto , Takayuki Imoto , Tsubasa Kashino , Takehisa Iwama , Nobuhide Miyachi
发明人： Masahiro Goto , Takayuki Imoto , Tsubasa Kashino , Takehisa Iwama , Nobuhide Miyachi
IPC分类号： A61L26/00
CPC分类号： A61L26/0095 , A61K8/0216 , A61K8/042 , A61K8/4946 , A61K8/65 , A61K8/73 , A61K8/8129 , A61K9/0014 , A61K9/06 , A61K9/7015 , A61K2800/10 , A61L26/0052 , A61L26/008 , A61Q19/00
摘要： There is provided a gel sheet that has high biocompatibility and safety, can contain both a hydrophilic medicinal agent and a hydrophobic medicinal agent, and provides an excellent feel in use during the application onto human skin or others. A gel sheet including: a lipid peptide gelator including a low molecular weight lipid peptide having a molecular weight of 1,000 or less or a pharmaceutically usable salt of the lipid peptide; and a polymeric compound, wherein the polymeric compound is included in an amount of more than 1% (w/w) and less than 50% (w/w) with respect to the total mass of the gel sheet.
摘要翻译：提供了具有高生物相容性和安全性的凝胶片，可以含有亲水药剂和疏水性药剂，并且在施用于人皮肤或其它物质时提供了极好的使用感。 1.一种凝胶片，其特征在于，包括：脂质肽凝胶剂，其包含分子量为1000以下的低分子量脂质肽或所述脂质肽的药学上可用的盐; 和聚合物，其中相对于凝胶片的总质量，聚合物的含量大于1％（w / w）且小于50％（w / w）。

3. 发明申请

US20120258059A1 COSMETIC, EXTERNAL SKIN PREPARATION, AND MEDICAL INSTRUMENT 有权
标题翻译：化妆品，外用皮肤制剂和医用仪器
公开(公告)号：US20120258059A1
公开(公告)日：2012-10-11
申请号：US13504026
申请日：2010-10-26
申请人： Takehisa Iwama , Keigo Matsumoto , Takayuki Imoto , Nobuhide Miyachi , Masahiro Goto
发明人： Takehisa Iwama , Keigo Matsumoto , Takayuki Imoto , Nobuhide Miyachi , Masahiro Goto
IPC分类号： A61K8/64 , A61Q19/00 , A61K47/42 , A61P7/04 , C07K5/062 , A61Q17/04
CPC分类号： A61K38/05 , A61K8/64 , A61K9/0014 , A61K9/06 , A61K9/12 , A61K31/715 , A61K31/734 , A61K38/39 , A61K47/10 , A61K47/36 , A61K47/42 , A61K47/542 , A61K2800/48 , A61L15/28 , A61L26/0023 , A61L2400/04 , A61Q19/00 , A61Q19/02 , A61Q19/08 , C07K5/06026 , C08L5/04
摘要： It is an object of the present invention to provide a cosmetic or external skin preparation that has an improved feel in use, e.g., excellent stretching on the skin surface, excellent permeation into the skin, and no stickiness, or crinkles. A cosmetic or an external skin preparation, and a medical instrument, comprising at least one lipid peptide-based gelator that contains a low-molecular lipid peptide of Formula (1): (where R1 to R3 are independently an organic group) or a pharmaceutically usable salt thereof.
摘要翻译：本发明的目的是提供一种具有改善使用感的化妆品或外用皮肤制剂，例如在皮肤表面上的优异拉伸，对皮肤的渗透性，无粘性，或皱纹。一种化妆品或外用皮肤制剂和医疗器械，其包含至少一种含有式（1）的低分子量脂质肽的脂质肽基凝胶剂：（其中R 1至R 3独立地为有机基团）或药学上其可用的盐。

4. 发明授权

US08999300B2 Cosmetic, external skin preparation, and medical instrument 有权
标题翻译：化妆品，外用皮肤制剂和医疗器械
公开(公告)号：US08999300B2
公开(公告)日：2015-04-07
申请号：US13504026
申请日：2010-10-26
申请人： Takehisa Iwama , Keigo Matsumoto , Takayuki Imoto , Nobuhide Miyachi , Masahiro Goto
发明人： Takehisa Iwama , Keigo Matsumoto , Takayuki Imoto , Nobuhide Miyachi , Masahiro Goto
IPC分类号： A61K8/18 , A61K8/00 , A61Q17/04 , A01N61/00 , A01N65/00 , A61K35/00 , A61K36/00 , A61K38/36 , A61P7/02 , C07K14/745 , A61K38/05 , A61K8/64 , A61K9/00 , A61K9/06 , A61K47/10 , A61K47/42 , A61L15/28 , A61L26/00 , A61Q19/00 , A61K31/715 , A61K31/734 , A61K38/39 , A61K9/12 , A61K47/36 , A61Q19/02 , A61Q19/08 , A61K47/48 , C07K5/062
CPC分类号： A61K38/05 , A61K8/64 , A61K9/0014 , A61K9/06 , A61K9/12 , A61K31/715 , A61K31/734 , A61K38/39 , A61K47/10 , A61K47/36 , A61K47/42 , A61K47/542 , A61K2800/48 , A61L15/28 , A61L26/0023 , A61L2400/04 , A61Q19/00 , A61Q19/02 , A61Q19/08 , C07K5/06026 , C08L5/04
摘要： It is an object of the present invention to provide a cosmetic or external skin preparation that has an improved feel in use, e.g., excellent stretching on the skin surface, excellent permeation into the skin, and no stickiness, or crinkles. A cosmetic or an external skin preparation, and a medical instrument, comprising at least one lipid peptide-based gelator that contains a low-molecular lipid peptide of Formula (1): (where R1 to R3 are independently an organic group) or a pharmaceutically usable salt thereof.
摘要翻译：本发明的目的是提供一种具有改善使用感的化妆品或外用皮肤制剂，例如在皮肤表面上的优异拉伸，对皮肤的渗透性，无粘性或皱纹。一种化妆品或外用皮肤制剂和医疗器械，其包含至少一种含有式（1）的低分子量脂质肽的脂质肽基凝胶剂：（其中R 1至R 3独立地为有机基团）或药学上其可用的盐。

5. 发明申请

US20140113976A1 PRODUCTION METHOD OF COSMETIC, PREPARATION METHOD OF GEL FOR COSMETICS, AND METHOD OF REDUCING USE AMOUNT OF POLYMER THICKENER BLENDED IN COSMETIC RAW MATERIALS 有权
标题翻译：化妆品的生产方法，化妆品凝胶的制备方法以及减少在化妆原料中混合的聚合物更大量的使用方法
公开(公告)号：US20140113976A1
公开(公告)日：2014-04-24
申请号：US14008912
申请日：2012-03-30
申请人： Keigo Matsumoto , Takayuki Imoto , Takehisa Iwama
发明人： Keigo Matsumoto , Takayuki Imoto , Takehisa Iwama
IPC分类号： A61K8/04 , A61K8/81 , A61K8/73 , A61K8/64
CPC分类号： A61K8/042 , A61K8/64 , A61K8/73 , A61K8/731 , A61K8/8147 , A61K2800/10 , A61K2800/48 , A61K2800/594 , A61Q19/00
摘要： A production method of a cosmetic that includes blending at least one lipid peptide-type gelator that contains a low-molecular lipid peptide or a pharmaceutically usable salt thereof at a ratio of 0.1% by weight to 0.5% by weight based on a mass of the polymer thickener to form a thickening gel; a preparation method of a gel for cosmetics that includes blending, into an aqueous medium for cosmetics, a polymer thickener and at least one lipid peptide-type gelator that contains a low-molecular lipid peptide or a pharmaceutically usable salt thereof at the above-mentioned ratio to form a gel; and a method of reducing the use amount of a polymer thickener in production of a cosmetic that includes blending at least one lipid peptide-type gelator that contains a low-molecular lipid peptide or a pharmaceutically usable salt thereof at the above-mentioned ratio.
摘要翻译：一种化妆品的制备方法，其包括以0.1重量％〜0.5重量％的比例混合含有低分子量脂质肽或其药学上可用的盐的至少一种脂质肽型胶凝剂，聚合物增稠剂形成增稠凝胶; 一种用于化妆品的凝胶的制备方法，其包括在上述化合物的水性介质中混合含有低分子量脂质肽或其药学上可用的盐的聚合物增稠剂和至少一种脂质肽型胶凝剂比例形成凝胶; 以及减少化妆品生产中的聚合物增稠剂的使用量的方法，其包括以上述比例混合至少一种含有低分子量脂质肽或其药学上可用的盐的脂质肽型凝胶剂。

6. 发明授权

US09566218B2 Production method of cosmetic, preparation method of gel for cosmetics, and method of reducing use amount of polymer thickener blended in cosmetic raw materials 有权
标题翻译：化妆品的制造方法，化妆品用凝胶的制备方法，以及减少化妆品原料中共混的聚合物增稠剂的使用量的方法
公开(公告)号：US09566218B2
公开(公告)日：2017-02-14
申请号：US14008912
申请日：2012-03-30
申请人： Keigo Matsumoto , Takayuki Imoto , Takehisa Iwama
发明人： Keigo Matsumoto , Takayuki Imoto , Takehisa Iwama
IPC分类号： A61K8/02 , A61K8/04 , A61K8/64 , A61Q19/00 , A61K8/73 , A61K8/81
CPC分类号： A61K8/042 , A61K8/64 , A61K8/73 , A61K8/731 , A61K8/8147 , A61K2800/10 , A61K2800/48 , A61K2800/594 , A61Q19/00
摘要： There is provided a production method of a cosmetic, a preparation method of a gel for cosmetics, and a method of reducing the use amount of a polymer thickener blended in cosmetic raw materials. The present invention relates to a production method of a cosmetic comprising blending, into the cosmetic raw material in addition to the polymer thickener, at least one lipid peptide-type gelator that contains a low-molecular lipid peptide or a pharmaceutically usable salt thereof at a ratio of 0.1% by weight to 0.5% by weight based on a mass of the polymer thickener to form a thickening gel; a preparation method of a gel for cosmetics comprising blending, into an aqueous medium for cosmetics, a polymer thickener and at least one lipid peptide-type gelator that contains a low-molecular lipid peptide or a pharmaceutically usable salt thereof at the above-mentioned ratio to form a gel; and a method of reducing the use amount of a polymer thickener in production of a cosmetic comprising blending, into the cosmetic raw material in addition to the polymer thickener, at least one lipid peptide-type gelator that contains a low-molecular lipid peptide or a pharmaceutically usable salt thereof at the above-mentioned ratio.
摘要翻译：提供了化妆品的制造方法，化妆品用凝胶的制备方法以及降低化妆品原料中混合的聚合物增稠剂的使用量的方法。本发明涉及一种化妆品的制造方法，其特征在于，除了聚合物增稠剂之外，还在化妆品原料中混合至少一种含有低分子脂质肽或其药学上可用的盐的脂质肽型胶凝剂基于聚合物增稠剂的质量，0.1重量％至0.5重量％的比例以形成增稠凝胶; 一种用于化妆品的凝胶的制备方法，包括将上述比例混合到化妆品的水性介质中，聚合物增稠剂和含有低分子脂质肽或其药学上可用的盐的至少一种脂质肽型胶凝剂形成凝胶; 以及减少化妆品生产中的聚合物增稠剂的使用量的方法，其包括除了聚合物增稠剂之外，将至少一种含有低分子量脂质肽或其药学上可接受的盐。

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