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1. 发明授权

US07235067B2 Sleeve valve catheters 有权
标题翻译：套管导管
公开(公告)号：US07235067B2
公开(公告)日：2007-06-26
申请号：US10382757
申请日：2003-03-06
申请人： Mary M. Morris , Timothy G. Laske , Kenneth T. Heruth , Michael R. Ujhelyi , Jesus W. Casas-Bejar , David S. Olson
发明人： Mary M. Morris , Timothy G. Laske , Kenneth T. Heruth , Michael R. Ujhelyi , Jesus W. Casas-Bejar , David S. Olson
IPC分类号： A61M25/16
CPC分类号： A61M25/0075
摘要： A catheter body includes an exit port over which a pressure responsive sleeve is formed that allows material to exit a lumen of the catheter body at a given pressure. In one embodiment, a surface of the sleeve is approximately flush with a surface of the catheter body. In another embodiment the sleeve includes a tapered edge.
摘要翻译：导管主体包括出口，在该出口处形成压力响应套筒，其允许材料在给定压力下离开导管体的内腔。在一个实施例中，套筒的表面与导管主体的表面大致齐平。在另一个实施例中，套筒包括锥形边缘。

2. 发明授权

US07413564B2 Slit valve catheters 有权
标题翻译：狭缝阀导管
公开(公告)号：US07413564B2
公开(公告)日：2008-08-19
申请号：US10382948
申请日：2003-03-06
申请人： Mary M. Morris , Timothy G. Laske , Kenneth T. Heruth , Michael R. Ujhelyi , Jesus W. Casas-Bejar
发明人： Mary M. Morris , Timothy G. Laske , Kenneth T. Heruth , Michael R. Ujhelyi , Jesus W. Casas-Bejar
IPC分类号： A61M25/16 , A61M25/18
CPC分类号： A61M25/0075
摘要： An external surface of a catheter body includes a pressure responsive slit formed in an indentation wherein a wall thickness of the catheter body within the indentation is less than a wall thickness of a major portion of the catheter body. Material exits a lumen of the catheter body, via the pressure responsive slit, when a pressure inside the lumen exceeds an external pressure.
摘要翻译：导管体的外表面包括形成在凹陷中的压力响应狭缝，其中压痕内导管体的壁厚小于导管主体的主要部分的壁厚。当内腔内的压力超过外部压力时，材料通过压力响应狭缝离开导管主体的内腔。

3. 发明授权

US09610423B2 Sleeve valve catheters 有权
公开(公告)号：US09610423B2
公开(公告)日：2017-04-04
申请号：US13486523
申请日：2012-06-01
申请人： Mary M. Morris , Timothy G. Laske , Kenneth T. Heruth , Michael R. Ujhelyi , Jesus W. Casas , David S. Olson
发明人： Mary M. Morris , Timothy G. Laske , Kenneth T. Heruth , Michael R. Ujhelyi , Jesus W. Casas , David S. Olson
IPC分类号： A61M1/00 , A61M25/00
CPC分类号： A61M25/0075
摘要： A catheter body includes an exit port over which a pressure responsive sleeve is formed that allows material to exit a lumen of the catheter body at a given pressure. In one embodiment, a surface of the sleeve is approximately flush with a surface of the catheter body.

4. 发明申请

US20120238964A1 SLEEVE VALVE CATHETERS 审中-公开
标题翻译：套管阀
公开(公告)号：US20120238964A1
公开(公告)日：2012-09-20
申请号：US13486611
申请日：2012-06-01
申请人： Mary M. Morris , Timothy G. Laske , Kenneth T. Heruth , Michael R. Ujhelyi , Jesus W. Casas , David S. Olson
发明人： Mary M. Morris , Timothy G. Laske , Kenneth T. Heruth , Michael R. Ujhelyi , Jesus W. Casas , David S. Olson
IPC分类号： A61M25/14
CPC分类号： A61M25/0075
摘要： A catheter body includes an exit port over which a pressure responsive sleeve is formed that allows material to exit a lumen of the catheter body at a given pressure. In one embodiment, a surface of the sleeve is approximately flush with a surface of the catheter body.
摘要翻译：导管主体包括出口，在该出口处形成压力响应套筒，其允许材料在给定压力下离开导管体的内腔。在一个实施例中，套筒的表面与导管主体的表面大致齐平。

5. 发明申请

US20120245533A1 SLEEVE VALVE CATHETERS 有权
公开(公告)号：US20120245533A1
公开(公告)日：2012-09-27
申请号：US13486523
申请日：2012-06-01
申请人： Mary M. Morris , Timothy G. Laske , Kenneth T. Heruth , Michael R. Ujhelyi , Jesus W. Casas , David S. Olson
发明人： Mary M. Morris , Timothy G. Laske , Kenneth T. Heruth , Michael R. Ujhelyi , Jesus W. Casas , David S. Olson
IPC分类号： A61M25/14
CPC分类号： A61M25/0075
摘要： A catheter body includes an exit port over which a pressure responsive sleeve is formed that allows material to exit a lumen of the catheter body at a given pressure. In one embodiment, a surface of the sleeve is approximately flush with a surface of the catheter body.

6. 发明授权

US5871530A Intracardiac defibrillation leads 失效
标题翻译：心脏除颤引导
公开(公告)号：US5871530A
公开(公告)日：1999-02-16
申请号：US62373
申请日：1998-04-17
申请人： Terrell M. Williams , Peter M. J. Mulier , John G. Keimel , Timothy G. Laske , Gregory A. Boser , Mary M. Morris , Xiaoyi Min
发明人： Terrell M. Williams , Peter M. J. Mulier , John G. Keimel , Timothy G. Laske , Gregory A. Boser , Mary M. Morris , Xiaoyi Min
IPC分类号： A61N1/04 , A61N1/05
CPC分类号： A61N1/0565 , A61N1/0563
摘要： A lead and a lead system for dispersion of a cardioversion/defibrillation electrode formed of one or more small diameter defibrillation electrodes in a heart chamber and for attaching a pace/sense electrode in contact with the heart. The small diameter defibrillation electrode or electrodes extend distally from the distal end of the lead body. If multiple electrodes are employed, they are preferably biased to spread apart when unrestrained and have a cross-section size small enough to be inserted into interstices of trabeculae in the ventricular chamber. The distal ends of the defibrillation electrodes may be free of attachment to the lead body or may be attached by a weak bond to the distal portion of the lead.
摘要翻译：一种用于在心室中由一个或多个小直径除颤电极形成的复律/除颤电极的分散的引线和引导系统，并且用于附接与心脏接触的步调/感测电极。小直径除颤电极或电极从引线体的远端向远端延伸。如果使用多个电极，则它们优选地被偏置以在不受限制的情况下展开，并且具有足够小的横截面尺寸以插入心室中的小梁的间隙中。除颤电极的远端可以没有附着到引线体，或者可以通过弱接合附着到引线的远端部分。

7. 发明授权

US6038472A Implantable defibrillator and lead system 失效
标题翻译：植入式除颤器和引导系统
公开(公告)号：US6038472A
公开(公告)日：2000-03-14
申请号：US840691
申请日：1997-04-29
申请人： Terrell M. Williams , Peter M. J. Mulier , John G. Keimel , Timothy G. Laske , Gregory A. Boser , Mary M. Morris , Xiaoyi Min
发明人： Terrell M. Williams , Peter M. J. Mulier , John G. Keimel , Timothy G. Laske , Gregory A. Boser , Mary M. Morris , Xiaoyi Min
IPC分类号： A61N1/04 , A61N1/05 , A61N1/39
CPC分类号： A61N1/0565 , A61N1/0563
摘要： A lead and a lead system for dispersion of a cardioversion/defibrillation electrode formed of one or more small diameter defibrillation electrodes in a heart chamber and for attaching a pace/sense electrode in contact with the heart. The small diameter defibrillation electrode or electrodes extend distally from the distal end of the lead body. If multiple electrodes are employed, they are preferably biased to spread apart when unrestrained and have a cross-section size small enough to be inserted into interstices of trabeculae in the ventricular chamber. The distal ends of the defibrillation electrodes may be free of attachment to the lead body or may be attached by a weak bond to the distal portion of the lead.
摘要翻译：一种用于在心室中由一个或多个小直径除颤电极形成的复律/除颤电极的分散的引线和引导系统，并且用于附接与心脏接触的步调/感测电极。小直径除颤电极或电极从引线体的远端向远端延伸。如果使用多个电极，则它们优选地被偏置以在不受限制的情况下展开，并且具有足够小的横截面尺寸以插入心室中的小梁的间隙中。除颤电极的远端可以没有附着到引线体，或者可以通过弱接合附着到引线的远端部分。

8. 发明授权

US06178355B1 Intracardiac defibrillation leads 失效
标题翻译：心脏除颤引导
公开(公告)号：US06178355B1
公开(公告)日：2001-01-23
申请号：US09216293
申请日：1998-12-18
申请人： Terrell M. Williams , Peter M. J. Mulier , John G. Keimel , Timothy G. Laske , Gregory A. Boser , Mary M. Morris , Xiaoyi Min
发明人： Terrell M. Williams , Peter M. J. Mulier , John G. Keimel , Timothy G. Laske , Gregory A. Boser , Mary M. Morris , Xiaoyi Min
IPC分类号： A61N105
CPC分类号： A61N1/0565 , A61N1/0563
摘要： A lead and a lead system for dispersion of a cardioversion/defibrillation electrode formed of one or more small diameter defibrillation electrodes in a heart chamber and for attaching a pace/sense electrode in contact with the heart. The small diameter defibrillation electrode or electrodes extend distally from the distal end of the lead body. If multiple electrodes are employed, they are preferably biased to spread apart when unrestrained and have a cross-section size small enough to be inserted into interstices of trabeculae in the ventricular chamber. The distal ends of the defibrillation electrodes may be free of attachment to the lead body or may be attached by a weak bond to the distal portion of the lead.
摘要翻译：一种用于在心室中由一个或多个小直径除颤电极形成的复律/除颤电极的分散的引线和引导系统，并且用于附接与心脏接触的步调/感测电极。小直径除颤电极或电极从引线体的远端向远端延伸。如果使用多个电极，则它们优选地被偏置以在不受限制的情况下展开，并且具有足够小的横截面尺寸以插入心室中的小梁的间隙中。除颤电极的远端可以没有附着到引线体，或者可以通过弱接合附着到引线的远端部分。

9. 发明授权

US06213988B1 Introducer with external hemostasis clip 失效
标题翻译：介绍与外部止血夹
公开(公告)号：US06213988B1
公开(公告)日：2001-04-10
申请号：US09021558
申请日：1998-02-10
申请人： Michael E. McIvor , Mary M. Morris , Judith Betz , Timothy G. Laske
发明人： Michael E. McIvor , Mary M. Morris , Judith Betz , Timothy G. Laske
IPC分类号： A61M500
CPC分类号： A61M25/0662 , A61M25/01
摘要： An introducer of the type employing an elongated introducer sleeve for receiving a catheter or lead body and an associated hemostasis clamp including a clamping member configured to engage the outer circumference of the introducer sleeve. The clamp is provided with a mechanism for maintaining the clamping member in engagement with said outer circumference of the sleeve to compress the outer circumference of the sleeve around a catheter or lead body inserted therethrough. In some embodiments the clamp takes the form of a hinged clamp provided with two jaws each having a recess adapted to engage a portion of the other circumference of the introducer sleeve. In other embodiments the clamp takes the form of interacting ramped members. The clamp is maintained in engagement with the sleeve either resiliently or by means of a latch.
摘要翻译：一种引入器，其采用细长导引器套筒，用于接纳导管或引线体，以及相关联的止血钳，其包括构造成接合引导器套筒的外圆周的夹紧构件。夹具设置有用于将夹紧构件保持与套筒的外周接合的机构，以将套筒的外周压缩成插入其中的导管或引线体。在一些实施例中，夹具采取铰链夹具的形式，其设置有两个钳口，每个钳口具有适于接合导引套筒的另一个圆周的一部分的凹部。在其他实施例中，夹具采取相互作用的倾斜构件的形式。夹具可以弹性地或通过闩锁保持与套筒接合。

10. 发明授权

US09352121B2 Systems and methods for variable injection flow 有权
公开(公告)号：US09352121B2
公开(公告)日：2016-05-31
申请号：US13409646
申请日：2012-03-01
申请人： Regina E. Groves , Jean-Pierre Lalonde , Timothy G. Laske , Claudia Lueckge , Dan Wittenberger , Ramin Sabbaghe-Kermani , Mahmoud Kabir-Seraj
发明人： Regina E. Groves , Jean-Pierre Lalonde , Timothy G. Laske , Claudia Lueckge , Dan Wittenberger , Ramin Sabbaghe-Kermani , Mahmoud Kabir-Seraj
IPC分类号： A61B18/02 , A61M25/00 , A61M39/28 , A61M39/22 , A61M25/01 , A61B18/00
CPC分类号： A61B18/02 , A61B18/0218 , A61B2018/00023 , A61B2018/00095 , A61B2018/00101 , A61B2018/00202 , A61B2018/0022 , A61B2018/0212 , A61B2018/0262 , A61B2018/0268 , A61M25/0029 , A61M25/007 , A61M39/22 , A61M39/28 , A61M2025/0025 , A61M2025/0079 , A61M2025/0175 , Y10T137/0318
摘要： Systems and methods for controllably variable fluid flow are disclosed that provide the ability to modify the effective cross-sectional area of the fluid delivery conduit available for fluid flow. Accordingly, selective control of these configurations allows fluid flow to be regulated as desired while the fluid delivery pressure remains the same. Additional configurations provided herein allow for the selective manipulation of a footprint or therapeutic pattern achievable with the medical device during a single procedure, negating the need for the removal and insertion of multiple devices to achieve the same variations in treatment geometry or characteristics.

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