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1. 发明授权

US08092486B2 Everted filter device 有权
标题翻译：过滤器
公开(公告)号：US08092486B2
公开(公告)日：2012-01-10
申请号：US12581960
申请日：2009-10-20
申请人： Marwane Berrada , Richard S. Kusleika , Kent D. Anderson
发明人： Marwane Berrada , Richard S. Kusleika , Kent D. Anderson
IPC分类号： A61M29/00 , A61B17/22
CPC分类号： A61F2/013 , A61F2002/018 , A61F2230/0006 , A61F2230/0069 , A61F2230/008
摘要： Everting filter devices and methods for using the devices, including using the devices as intra-vascular filters to filter thrombus, emboli, and plaque fragments from blood vessels. The filter devices include a filter body nominally tubular in shape and having a large proximal opening. The filter body can extend from a proximal first end region distally over the non-everted exterior surface of the filter, further extending distally to a distal-most region, then converging inwardly and extending proximally toward the filter second end region, forming a distal everted cavity. The degree of eversion of the filter can be controlled by varying the distance between the filter first end region near the proximal opening and the closed second end region. Bringing the filter first and second end regions closer together can bring filter material previously on the non-everted filter exterior to occupy the distal-most region.
摘要翻译：永久过滤装置和使用装置的方法，包括使用装置作为血管内过滤器来从血管中过滤血栓，栓塞和斑块碎片。过滤装置包括标称管状的过滤器体，并具有大的近端开口。过滤器主体可以从近端第一端部区域远离过滤器的非转角外表面延伸，并进一步向远端延伸到最远侧区域，然后向内收敛并向近端朝向过滤器第二端部区域延伸，形成远端腔。可以通过改变近侧开口附近的过滤器第一端部区域与闭合的第二端部区域之间的距离来控制过滤器的外翻度。使过滤器第一和第二端部区域更靠近在一起可以将过滤材料预先放置在非转角过滤器外部以占据最远侧区域。

2. 发明申请

US20120053615A1 RAPID EXCHANGE CATHETERS USABLE WITH EMBOLIC PROTECTION DEVICES 有权
标题翻译：快速交换电缆可用于嵌入式保护装置
公开(公告)号：US20120053615A1
公开(公告)日：2012-03-01
申请号：US13223774
申请日：2011-09-01
申请人： Daniel O. Adams , Marwane Berrada , Cathleen M. von Lehe , Richard S. Kusleika
发明人： Daniel O. Adams , Marwane Berrada , Cathleen M. von Lehe , Richard S. Kusleika
IPC分类号： A61B17/22
CPC分类号： A61F2/013 , A61F2002/011 , A61F2002/018 , A61F2230/0008 , A61F2230/008
摘要： Catheters, assemblies, and methods for delivering and recovering embolic protection devices. Catheters are provided that can be advanced over single length guide wires and which can be retracted over single length wire shafts of distal embolic protection devices. One catheter is a two-port catheter having two sidewall ports, a distal end port, and a proximal end port. The two-port catheter can be advanced over a guide wire threaded between the distal end port and the distal sidewall port. An embolic protection device wire shaft can be back loaded into the distal end port and out the proximal sidewall port. A three-port catheter includes a distal end port, and distal, intermediate, and proximal sidewall ports.
摘要翻译：用于输送和恢复栓塞保护装置的导管，组件和方法。提供导管，其可以在单长导丝上前进，并且可以在远端栓塞保护装置的单长丝线轴上缩回。一个导管是具有两个侧壁端口，远端端口和近端端口的双端口导管。双端口导管可以在远端端口和远端侧壁端口之间的引导线上前进。栓塞保护装置线轴可以被背负载到远端端口中并且从近端侧壁端口出来。三端口导管包括远端端口以及远端，中间和近端侧壁端口。

3. 发明申请

US20080188888A1 RAPID EXCHANGE CATHETERS USABLE WITH EMBOLIC PROTECTION DEVICES 审中-公开
标题翻译：快速交换电缆可用于嵌入式保护装置
公开(公告)号：US20080188888A1
公开(公告)日：2008-08-07
申请号：US12100837
申请日：2008-04-10
申请人： Daniel O. Adams , Marwane Berrada , Cathleen M. von Lehe , Richard S. Kusleika
发明人： Daniel O. Adams , Marwane Berrada , Cathleen M. von Lehe , Richard S. Kusleika
IPC分类号： A61M29/00
CPC分类号： A61F2/013 , A61F2002/011 , A61F2002/018 , A61F2230/0008 , A61F2230/008
摘要： Catheters, assemblies, and methods for delivering and recovering embolic protection devices. Catheters are provided that can be advanced over single length guide wires and which can be retracted over single length wire shafts of distal embolic protection devices. One catheter is a two-port catheter having two sidewall ports, a distal end port, and a proximal end port. The two-port catheter can be advanced over a guide wire threaded between the distal end port and the distal sidewall port. An embolic protection device wire shaft can be back loaded into the distal end port and out the proximal sidewall port. A three-port catheter includes a distal end port, and distal, intermediate, and proximal sidewall ports. The distal sidewall port can be dimensioned to accept passage of a filter body through the port. The distal end port can be dimensioned to accept only a guide wire to provide a smooth transition from the guide wire to the small profile distal end. The guide wire can extend between the distal end port and the intermediate port while the filter body shaft can extend through the proximal port, to be distally urged through the distal sidewall port. Another catheter embodiment is a slotted catheter, including a biased, normally open slot over most of its length. The slot can be sufficiently small to resist unwanted transverse movement of a wire through the slot. The slotted catheter can be retracted over a wire by forcing the wire through the resilient slot.
摘要翻译：用于输送和恢复栓塞保护装置的导管，组件和方法。提供导管，其可以在单长导丝上前进，并且可以在远端栓塞保护装置的单长丝线轴上缩回。一个导管是具有两个侧壁端口，远端端口和近端端口的双端口导管。双端口导管可以在远端端口和远端侧壁端口之间的引导线上前进。栓塞保护装置线轴可以被背负载到远端端口中并且从近端侧壁端口出来。三端口导管包括远端端口以及远端，中间和近端侧壁端口。远端侧壁端口的尺寸可以容纳过滤体通过端口的通道。该远端端口的尺寸可被设计为仅接纳导丝，以提供从导丝到小轮廓远端的平滑过渡。引导线可以在远端端口和中间端口之间延伸，同时过滤器主体轴可以延伸穿过近端端口，以便通过远端侧壁端口被远离地推动。另一个导管实施例是开槽导管，其包括在其大部分长度上的偏置的常开狭槽。槽可以足够小以阻止电线穿过狭槽的不必要的横向移动。狭缝导管可以通过将线穿过弹性槽而缩回到导线上。

4. 发明申请

US20100179491A1 RAPID EXCHANGE CATHETERS USABLE WITH EMBOLIC PROTECTION DEVICES 有权
标题翻译：快速交换电缆可用于嵌入式保护装置
公开(公告)号：US20100179491A1
公开(公告)日：2010-07-15
申请号：US12729914
申请日：2010-03-23
申请人： Daniel O. Adams , Marwane Berrada , Cathleen M. von Lehe , Richard S. Kusleika
发明人： Daniel O. Adams , Marwane Berrada , Cathleen M. von Lehe , Richard S. Kusleika
IPC分类号： A61M25/00 , A61F2/06
CPC分类号： A61F2/013 , A61F2002/011 , A61F2002/018 , A61F2230/0008 , A61F2230/008
摘要： Catheters, assemblies, and methods for delivering and recovering embolic protection devices. Catheters are provided that can be advanced over single length guide wires and which can be retracted over single length wire shafts of distal embolic protection devices. One catheter is a two-port catheter having two sidewall ports, a distal end port, and a proximal end port. The two-port catheter can be advanced over a guide wire threaded between the distal end port and the distal sidewall port. An embolic protection device wire shaft can be back loaded into the distal end port and out the proximal sidewall port. A three-port catheter includes a distal end port, and distal, intermediate, and proximal sidewall ports. The distal sidewall port can be dimensioned to accept passage of a filter body through the port. The distal end port can be dimensioned to accept only a guide wire to provide a smooth transition from the guide wire to the small profile distal end. The guide wire can extend between the distal end port and the intermediate port while the filter body shaft can extend through the proximal port, to be distally urged through the distal sidewall port. Another catheter embodiment is a slotted catheter, including a biased, normally open slot over most of its length. The slot can be sufficiently small to resist unwanted transverse movement of a wire through the slot. The slotted catheter can be retracted over a wire by forcing the wire through the resilient slot.
摘要翻译：用于输送和恢复栓塞保护装置的导管，组件和方法。提供导管，其可以在单长导丝上前进，并且可以在远端栓塞保护装置的单长丝线轴上缩回。一个导管是具有两个侧壁端口，远端端口和近端端口的双端口导管。双端口导管可以在远端端口和远端侧壁端口之间的引导线上前进。栓塞保护装置线轴可以被背负载到远端端口中并且从近端侧壁端口出来。三端口导管包括远端端口以及远端，中间和近端侧壁端口。远端侧壁端口的尺寸可以容纳过滤体通过端口的通道。该远端端口的尺寸可被设计为仅接纳导丝，以提供从导丝到小轮廓远端的平滑过渡。引导线可以在远端端口和中间端口之间延伸，同时过滤器主体轴可以延伸穿过近端端口，以便通过远端侧壁端口被远离地推动。另一个导管实施例是开槽导管，其包括在其大部分长度上的偏置的常开狭槽。槽可以足够小以阻止电线穿过狭槽的不必要的横向移动。狭缝导管可以通过将线穿过弹性槽而缩回到导线上。

5. 发明授权

US09775701B2 Distal protection devices having controllable wire motion 有权
公开(公告)号：US09775701B2
公开(公告)日：2017-10-03
申请号：US13309658
申请日：2011-12-02
申请人： Richard S. Kusleika , Daniel O. Adams , Kent D. Anderson , Dale Nelson , Jeffrey D. Santer
发明人： Richard S. Kusleika , Daniel O. Adams , Kent D. Anderson , Dale Nelson , Jeffrey D. Santer
IPC分类号： A61F2/01 , A61M25/09 , A61M25/00
CPC分类号： A61F2/013 , A61F2002/015 , A61F2002/018 , A61F2230/0008 , A61F2230/0069 , A61F2230/008 , A61F2230/0093 , A61M25/09 , A61M2025/0079 , A61M2025/09183
摘要： A distal protection device for use in a body lumen includes a functional element, which may be a filter or an occlusive element. The device includes a first elongate member, a second elongate member carried by the first elongate member, and the functional element carried by the second elongate member. Motion of the first elongate member can be independent of the motion of the functional element.

6. 发明授权

US08409242B2 Embolic filters with controlled pore size 有权
标题翻译：具有可控孔径的栓塞过滤器
公开(公告)号：US08409242B2
公开(公告)日：2013-04-02
申请号：US13169229
申请日：2011-06-27
申请人： Thomas L. Clubb , Richard S. Kusleika , Kent D. Anderson , Marwane S. Berrada
发明人： Thomas L. Clubb , Richard S. Kusleika , Kent D. Anderson , Marwane S. Berrada
IPC分类号： A61M29/00
CPC分类号： A61F2/01 , A61F2/013 , A61F2002/018 , A61F2230/0006 , A61F2230/0008 , A61F2230/0067 , A61F2230/0069 , A61F2230/008 , D04B1/16 , D04C1/02 , D04C3/48 , D10B2509/06
摘要： A device for filtering emboli from blood flowing through a lumen defined by the walls of a vessel in a patient's body. The device has a filter element being expandable from a collapsed configuration to an expanded configuration. The filter element includes a material having pores, and the material having pores includes cylindrical wires having at least three different diameters arranged in a pattern of graduated diameters.
摘要翻译：用于从血液流过血液的装置，该血液通过由患者体内的血管壁限定的内腔。该装置具有可从折叠构型扩展到扩展构型的过滤元件。过滤元件包括具有孔的材料，并且具有孔的材料包括具有以刻度直径的图案排列的至少三个不同直径的圆柱形线。

7. 发明授权

US08182507B2 Vascular protection devices and methods of use 有权
标题翻译：血管保护装置及使用方法
公开(公告)号：US08182507B2
公开(公告)日：2012-05-22
申请号：US11444004
申请日：2006-05-31
申请人： Kent D. Anderson , John Oslund , Richard S. Kusleika , Daniel O. Adams
发明人： Kent D. Anderson , John Oslund , Richard S. Kusleika , Daniel O. Adams
IPC分类号： A61M29/00
CPC分类号： A61F2/013 , A61B17/12022 , A61B17/12172 , A61B17/221 , A61B2017/00867 , A61B2017/22045 , A61F2002/015 , A61F2002/018 , A61F2230/0006 , A61F2230/0008 , A61F2230/0067 , A61F2230/008 , A61F2230/0093 , A61M25/0074 , A61M25/0082 , A61M25/09 , A61M2025/0079 , A61M2025/09183
摘要： An embolic protection device or system for use in a lumen of a vessel in a patient's vascular system. The device filters debris and blood clots in a body lumen and/or prevents them from moving distally from a treatment site in a vessel and causing emboli. The device may include a filter placed distally of the treatment site. The device may include an occlusive element placed either distally or proximally of the treatment site.
摘要翻译：一种用于患者血管系统中血管内腔的栓塞保护装置或系统。该装置过滤器体内的碎屑和血块，和/或阻止它们远离血管内的治疗部位并引起栓塞。该装置可以包括放置在治疗部位的远侧的过滤器。该装置可以包括放置在治疗部位的远侧或近端的闭塞元件。

8. 发明授权

US08083762B2 Distal protection devices having controllable wire motion 有权
标题翻译：远端保护装置具有可控制的线运动
公开(公告)号：US08083762B2
公开(公告)日：2011-12-27
申请号：US12112534
申请日：2008-04-30
申请人： Richard S. Kusleika , Daniel O. Adams , Kent D. Anderson , Dale Nelson , Jeffrey D. Santer
发明人： Richard S. Kusleika , Daniel O. Adams , Kent D. Anderson , Dale Nelson , Jeffrey D. Santer
IPC分类号： A61M29/00
CPC分类号： A61F2/013 , A61F2002/015 , A61F2002/018 , A61F2230/0008 , A61F2230/0069 , A61F2230/008 , A61F2230/0093 , A61M25/09 , A61M2025/0079 , A61M2025/09183
摘要： A distal protection device for use in a body lumen. The device includes a functional element which may be a filter or an occlusive element. The device includes means for controlling the movement and placement of the functional element along a guidewire. Motion of the guidewire can be independent of the motion of the functional element.
摘要翻译：用于体腔内的远端保护装置。该装置包括可以是过滤器或闭塞元件的功能元件。该装置包括用于控制沿着导丝的功能元件的移动和放置的装置。导丝的运动可以独立于功能元件的运动。

9. 发明授权

US07998166B2 Distal protection device with local drug delivery to maintain patency 有权
标题翻译：远端保护装置具有局部药物输送以维持通畅
公开(公告)号：US07998166B2
公开(公告)日：2011-08-16
申请号：US12174251
申请日：2008-07-16
申请人： Kent D. Anderson , Richard S. Kusleika , Jennifer L. Pavlovic , Chad J. Volk , Gary A. Thill , Jeannine B. Baden
发明人： Kent D. Anderson , Richard S. Kusleika , Jennifer L. Pavlovic , Chad J. Volk , Gary A. Thill , Jeannine B. Baden
IPC分类号： A61M29/00
CPC分类号： A61F2/013 , A61F2002/018 , A61F2230/0008 , A61F2230/0067 , A61F2250/0068
摘要： The present invention provides for a drug delivery mechanism for use with a protection device. The protection device has an expandable filter. The drug delivery mechanism automatically delivers a drug to the filter without requiring the intervention of the operator of the protection device. The drug delivered to the filter facilitates continued filter patency during the medical procedure.
摘要翻译：本发明提供了用于与保护装置一起使用的药物递送机构。保护装置具有可扩展的过滤器。药物递送机构自动地将药物递送到过滤器，而不需要保护装置的操作者的干预。输送到过滤器的药物有助于在医疗过程中继续过滤通气。

10. 发明申请

US20080200947A1 DISTAL PROTECTION DEVICES HAVING CONTROLLABLE WIRE MOTION 有权
标题翻译：具有可控电线运动的远程保护装置
公开(公告)号：US20080200947A1
公开(公告)日：2008-08-21
申请号：US12112534
申请日：2008-04-30
申请人： Richard S. Kusleika , Daniel O. Adams , Kent D. Anderson , Dale Nelson , Jeffrey D. Santer
发明人： Richard S. Kusleika , Daniel O. Adams , Kent D. Anderson , Dale Nelson , Jeffrey D. Santer
IPC分类号： A61F2/01
CPC分类号： A61F2/013 , A61F2002/015 , A61F2002/018 , A61F2230/0008 , A61F2230/0069 , A61F2230/008 , A61F2230/0093 , A61M25/09 , A61M2025/0079 , A61M2025/09183
摘要： A distal protection device for use in a body lumen. The device includes a functional element which may be a filter or an occlusive element. The device includes means for controlling the movement and placement of the functional element along a guidewire. Motion of the guidewire can be independent of the motion of the functional element.
摘要翻译：用于体腔内的远端保护装置。该装置包括可以是过滤器或闭塞元件的功能元件。该装置包括用于控制沿着导丝的功能元件的移动和放置的装置。导丝的运动可以独立于功能元件的运动。

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