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1. 发明申请

US20050209785A1 Systems and methods for disease diagnosis 审中-公开
标题翻译：疾病诊断系统和方法
公开(公告)号：US20050209785A1
公开(公告)日：2005-09-22
申请号：US11068102
申请日：2005-02-27
申请人： Martin Wells , Christopher Turner , Peter Jacobson
发明人： Martin Wells , Christopher Turner , Peter Jacobson
IPC分类号： G06E1/00 , G06F15/18 , G06F19/00 , G06G7/00
CPC分类号： G16H50/20 , G16B25/00 , G16B40/00
摘要： The present invention is directed to improved systems and methods for distinguishing and classifying subjects based on analysis of biological materials. Methods for the analysis of multivariate data collected from a plurality of subjects of known class are provided. The results of such analyses include a set of intermediate combined classifiers as well as a metal variable that relates directly to the classes of the subjects in a training population. Both the intermediate combined classifiers and the final meta model are used to distinguish and classify subjects of previously unknown class.
摘要翻译：本发明涉及用于基于生物材料分析来区分和分类受试者的改进系统和方法。提供了从已知类别的多个受试者收集的多变量数据的分析方法。这种分析的结果包括一组中间组合分类器以及与培训人群中的主题类别直接相关的金属变量。中间组合分类器和最终元模型都用于区分和分类以前未知类的主题。

2. 外观设计

USD813937S1 Drum stick finger holder 有权
公开(公告)号：USD813937S1
公开(公告)日：2018-03-27
申请号：US29593524
申请日：2017-02-09
申请人： Peter Jacobson
设计人： Peter Jacobson

3. 发明授权

US5558097A Method for tachyarrhythmia detection 失效
标题翻译：快速性心律失常检测方法
公开(公告)号：US5558097A
公开(公告)日：1996-09-24
申请号：US287843
申请日：1994-08-09
申请人： Peter Jacobson , Daniel Kroiss
发明人： Peter Jacobson , Daniel Kroiss
IPC分类号： A61N1/37 , A61B5/0464
CPC分类号： A61N1/37 , A61N1/3702
摘要： A method and apparatus for optimizing the sensing circuit of a tachyarrhythmia detector for use with direct heart (cardiac) electrodes. The method is applied to detection of ventricular fibrillation and multifocal ventricular tachyarrhythmia, with rejection of T wave and pacing artifact. The sensing circuit optimized with this method includes a third-order high-pass filter followed by at least one comparator, with the filter corner frequency near 16 Hz and the comparator threshold near 0.40 mV referred to the input, in-band.
摘要翻译：一种用于优化用于直接心脏（心脏）电极的快速心律失常检测器的感测电路的方法和装置。该方法用于检测心室颤动和多灶性心律失常，伴有T波和起搏假体的排斥。利用这种方法优化的感测电路包括一个三阶高通滤波器，后面是至少一个比较器，滤波器转角频率接近16 Hz，而比较器阈值接近0.40 mV则是带内输入。

4. 发明授权

US5513645A Holter functions with a zoom feature 失效
标题翻译： Holter功能与缩放功能
公开(公告)号：US5513645A
公开(公告)日：1996-05-07
申请号：US340240
申请日：1994-11-16
申请人： Peter Jacobson , Daniel Kroiss
发明人： Peter Jacobson , Daniel Kroiss
IPC分类号： A61N1/39 , A61B5/0432
CPC分类号： A61N1/3925
摘要： This invention provides an improved Holter function in an implantable device for arrhythrnia monitoring or therapy. One improvement consists of a zoom feature which stores information about an arrhythmia episode at several levels of detail, with increasing levels of detail corresponding to shorter recording periods, and with a way to display the relation in time of the recordings at different levels of detail. The invention also introduces a novel implantable Holter function called an event log, which records time-stamped events once each minute, on changes in detected rhythm, or on application of antiarrhythmia therapy. The invention also provides logic for arbitrating which arrhythmia episodes the device saves in its memory.
摘要翻译：本发明提供了一种用于心律失常监测或治疗的可植入装置中的改进的Holter功能。一个改进包括缩放功能，其在几个细节级别上存储关于心律失常事件的信息，并且具有与较短记录周期相对应的增加的细节水平，以及以不同细节级别显示记录时间关系的方式。本发明还引入了称为事件日志的新颖的可植入动态心电图功能，每分钟记录一次时间戳事件，检测到的节律变化或应用抗心律失常治疗。本发明还提供用于仲裁设备在其存储器中保存的哪些心律失常发作的逻辑。

5. 发明申请

US20120059389A1 Implantable Micro-Generator Devices with Optimized Configuration, Methods of Use, Systems and Kits Therefor 审中-公开
标题翻译：具有优化配置，使用方法，系统和套件的可植入微型发电机设备
公开(公告)号：US20120059389A1
公开(公告)日：2012-03-08
申请号：US13202026
申请日：2010-02-22
申请人： Loren Robert Larson , Brian Lane Larson , Peter Jacobson , Paul Paspa
发明人： Loren Robert Larson , Brian Lane Larson , Peter Jacobson , Paul Paspa
IPC分类号： A61N1/378 , A61B19/00 , A61N1/36 , A61N1/05 , A61N1/365
CPC分类号： A61N1/3785 , A61N1/056 , A61N1/37205 , A61N1/37252 , G06F19/3418 , H02K35/02
摘要： Disclosed are various implantable medical devices adapted and configured to operation with a micro-generator comprising: an elongated housing; one or more longitudinally slidable elongated magnets; one or more coils positioned exteriorly, interiorly or integrally along at least a portion of the housing; a power wire in electrical communication with the one or more coils and with an implantable medical device; wherein the implantable micro-generator is adapted and configured to generate energy and communicate the generated energy to the implantable medical device. Additionally, methods of deploying and using the medical devices are contemplated, as well as systems, kits, and communication networks.
摘要翻译：公开了适用于和配置为与微型发生器一起操作的各种可植入医疗装置，包括：细长壳体; 一个或多个可纵向滑动的细长磁体; 一个或多个线圈沿着壳体的至少一部分外部，内部或整体地定位; 与所述一个或多个线圈和可植入医疗装置电连通的电力线; 其中所述可植入微发生器被适配和配置成产生能量并将所产生的能量传递到所述可植入医疗装置。此外，预期部署和使用医疗设备的方法以及系统，套件和通信网络。

6. 发明申请

US20110135792A1 SANDWICH AND METHOD FOR FORMING 审中-公开
标题翻译：三明治及其形成方法
公开(公告)号：US20110135792A1
公开(公告)日：2011-06-09
申请号：US12958313
申请日：2010-12-01
申请人： Peter Jacobson , Marc de Longree
发明人： Peter Jacobson , Marc de Longree
IPC分类号： A21D13/00 , A23L1/00 , A21D10/04 , A21D8/06
CPC分类号： C08L33/14
摘要： A sandwich includes a partially baked sandwich insert and a chemically-leavened batter layer that envelops at least a portion of the partially baked sandwich insert. The partially baked sandwich insert includes a filling that is completely enveloped by a yeast-leavened dough.
摘要翻译：三明治包括部分烘烤的三明治插入物和包封部分烘烤的三明治插入物的至少一部分的化学发酵的面糊层。部分烘烤的三明治插入物包括由酵母发酵的面团完全包封的填充物。

7. 发明申请

US20070088418A1 Delivery system for implantable biostimulator 有权
标题翻译：可植入生物刺激仪的输送系统
公开(公告)号：US20070088418A1
公开(公告)日：2007-04-19
申请号：US11549574
申请日：2006-10-13
申请人： Peter Jacobson
发明人： Peter Jacobson
IPC分类号： A61N1/05
CPC分类号： A61N1/3962 , A61M25/0662 , A61N1/056 , A61N1/0573 , A61N1/0587 , A61N1/059 , A61N1/3621 , A61N1/3627 , A61N1/36514 , A61N1/36542 , A61N1/368 , A61N1/3684 , A61N1/3704 , A61N1/3706 , A61N1/3708 , A61N1/372 , A61N1/37205 , A61N1/37217 , A61N1/37252 , A61N1/3727 , A61N1/37288 , A61N1/375 , A61N1/3756 , A61N1/3925 , A61N1/3956 , A61N2001/058 , H04B13/005
摘要： A delivery system for implanting a biostimulation device comprising a stylet extending along an axis from knob end to a threaded end configured to engage an internally threaded nut of the biostimulation device and a catheter tube configured to axially contain the stylet. The catheter tube comprises a feature that engages a corresponding feature on the biostimulation device whereby the stylet can be rotated relative to the catheter tube for disengagement of the stylet threaded end from the biostimulation device threaded end.
摘要翻译：一种用于植入生物刺激装置的递送系统，所述生物刺激装置包括沿着轴从手柄端延伸到螺纹端的探针，所述螺纹端构造成与所述生物刺激装置的内螺纹螺母接合，以及构造成轴向容纳所述探针的导管。导管包括与生物刺激装置相对应的特征接合的特征，由此探针相对于导管可旋转，以使探针螺纹端与生物刺激装置螺纹端脱离接触。

8. 发明申请

US20070088394A1 Leadless cardiac pacemaker system for usage in combination with an implantable cardioverter-defibrillator 有权
标题翻译：无铅心脏起搏器系统，用于与植入式心律转复除颤器组合使用
公开(公告)号：US20070088394A1
公开(公告)日：2007-04-19
申请号：US11549599
申请日：2006-10-13
申请人： Peter Jacobson
发明人： Peter Jacobson
IPC分类号： A61N1/00
CPC分类号： A61N1/3962 , A61M25/0662 , A61N1/056 , A61N1/0573 , A61N1/0587 , A61N1/059 , A61N1/3621 , A61N1/3627 , A61N1/36514 , A61N1/36542 , A61N1/368 , A61N1/3684 , A61N1/3704 , A61N1/3706 , A61N1/3708 , A61N1/372 , A61N1/37205 , A61N1/37217 , A61N1/37252 , A61N1/3727 , A61N1/37288 , A61N1/375 , A61N1/3756 , A61N1/3925 , A61N1/3956 , A61N2001/058 , H04B13/005
摘要： A cardiac pacing system comprising one or more leadless cardiac pacemakers configured for implantation in electrical contact with a cardiac chamber and configured to perform cardiac pacing functions in combination with a co-implanted implantable cardioverter-defibrillator (ICD). The leadless cardiac pacemaker comprises at least two leadless electrodes configured for delivering cardiac pacing pulses, sensing evoked and/or natural cardiac electrical signals, and bidirectionally communicating with the co-implanted ICD.
摘要翻译：一种心脏起搏系统，包括一个或多个无引线心脏起搏器，其被配置为植入与心室的电接触并被配置为与共同植入的可置换心脏转复除颤器（ICD）结合执行心脏起搏功能。无引线心脏起搏器包括至少两个配置用于递送心脏起搏脉冲，感测诱发和/或自然心电信号以及与共同植入的ICD双向通信的无引线电极。

9. 发明授权

US5564430A Automatic control of the sensing threshold for monitoring cardiac rhythm in a implantable device 失效
标题翻译：自动控制用于监测可植入装置中的心律的感测阈值
公开(公告)号：US5564430A
公开(公告)日：1996-10-15
申请号：US340624
申请日：1994-11-16
申请人： Peter Jacobson , Daniel Kroiss
发明人： Peter Jacobson , Daniel Kroiss
IPC分类号： A61N1/37 , A61B5/0456
CPC分类号： A61N1/3704 , Y10S128/901
摘要： An improved automatic sensing threshold control for cardiac rhythm detection in an implantable device. The improvement includes setting the sensing threshold according to the amplitude of both sensed signals corresponding to cardiac activity and sensed noise, for setting the threshold substantially below the sensed signal amplitude, but above the noise amplitude. The invention provides absolute refractory periods after pacing or sensing, followed by a retriggerable noise refractory period. Following sensing the device sets the sensing threshold to approximately one-fourth of the measured amplitude, and then increases the threshold when it detects noise.
摘要翻译：在可植入装置中用于心律检测的改进的自动感测阈值控制。该改进包括根据对应于心脏活动和感测噪声的两个感测信号的幅度设置感测阈值，用于将阈值设置为基本上低于感测信号幅度，但高于噪声幅度。本发明提供了起搏或感测之后的绝对不应期，随后是可再触发的不良时期。在感测之后，设备将感测阈值设置为测量幅度的大约四分之一，然后在检测到噪声时增加阈值。

10. 发明授权

US5545181A Implantable defibrillator/pacer using negative voltage supplies 失效
标题翻译：可植入除颤器/起搏器使用负电源
公开(公告)号：US5545181A
公开(公告)日：1996-08-13
申请号：US320854
申请日：1994-10-11
申请人： Peter Jacobson , Daniel Kroiss , Alan Ostroff
发明人： Peter Jacobson , Daniel Kroiss , Alan Ostroff
IPC分类号： A61N1/39 , A61N1/36
CPC分类号： A61N1/3962 , A61N1/3918 , A61N1/3912
摘要： A configuration for generating single capacitor multiphasic shocks is disclosed, using an H-bridge with four switches to connect an energy storage capacitor to a load with selectable polarity. The improvement concerns referring the negative side of the shock generator to a supply voltage which is negative with respect to pacing and sensing ground, and to connect the battery positive terminal to this same ground. This configuration permits operating the low side switches in the H-bridge, the pace/sense circuits, and the control circuitry from negative supplies derived without inversion from the negative battery terminal.
摘要翻译：公开了用于产生单电容器多相冲击的配置，使用具有四个开关的H桥将能量存储电容器连接到具有可选极性的负载。改进是将冲击发生器的负侧指向相对于起搏和感测地面为负的电源电压，并将电池正极端子连接到同一个地面。这种配置允许H桥中的低侧开关，步速/感测电路和控制电路从负电池端子的反向供电。

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