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1. 发明申请

US20070255251A1 Microprojection Array Application With High Barrier Retainer 审中-公开
标题翻译：高阻挡保护器的微喷射阵列应用
公开(公告)号：US20070255251A1
公开(公告)日：2007-11-01
申请号：US11684544
申请日：2007-03-09
申请人： Martin Panchula , Ling-Kang Tong
发明人： Martin Panchula , Ling-Kang Tong
IPC分类号： A61M31/00
CPC分类号： A61M37/0015 , A61M2037/0023 , A61M2037/0046
摘要： A transdermal drug delivery system with a high barrier retainer for holding a microprojection member for disrupting a body surface to an individual. The retainer is made of a high barrier material (such as metal) that is easily sterilizable, such as by heat, and can be used for keeping out contamination and maintaining the environment of the microprojection member.
摘要翻译：一种具有高屏障保持器的透皮药物递送系统，用于保持用于破坏身体表面的个人的微突出物构件。保持器由诸如通过热容易灭菌的高阻隔材料（例如金属）制成，并且可以用于防止污染并保持微喷射构件的环境。

2. 发明申请

US20100132699A1 BURST VALVE FOR AEROSOL DEVICE 审中-公开
标题翻译：用于航空器装置的冲击阀
公开(公告)号：US20100132699A1
公开(公告)日：2010-06-03
申请号：US12615153
申请日：2009-11-09
申请人： Victor BUROLLA , Henning Graskov , Ling-Kang Tong
发明人： Victor BUROLLA , Henning Graskov , Ling-Kang Tong
IPC分类号： A61M11/00
CPC分类号： A61M15/0028 , A61M11/042 , A61M15/00
摘要： Aerosol dispensing devices and methods for using the same for administering aerosolized drugs to a subject are provided. Aspects of the aerosol dispensing device include an aerosol production unit configured to produce an aerosol from a liquid containing a pharmaceutically active drug, and a burst valve adapted to mechanically open in response to a subject's inhalation. The burst valve is configured to prevent airflow through the device until the subject's inhalation produces an operational pressure difference across the burst valve. In some embodiments, the operational pressure difference can be 15 cm H2O or less. Aspects of the invention can also include a heating element configured to evaporate water from aerosol droplets. The devices and methods of the invention find use in a variety of applications, such as in applications in which it is desired to administer an aerosolized drug to a subject.
摘要翻译：提供了气雾剂分配装置及其用于向受试者施用雾化药物的方法。气溶胶分配装置的方面包括气溶胶生成单元，其构造成从含有药物活性药物的液体产生气雾剂，以及适于根据受试者的吸入机械打开的爆裂阀。爆破阀配置为防止气流通过设备，直到受试者的吸入产生跨爆破阀的操作压力差。在一些实施例中，操作压力差可以是15cm H 2 O或更小。本发明的方面还可以包括被配置为从气溶胶液滴蒸发水的加热元件。本发明的装置和方法可用于各种应用中，例如在期望向受试者施用雾化药物的应用中。

3. 发明申请

US20070293814A1 Coatable transdermal delivery microprojection assembly 审中-公开
标题翻译：涂层透皮递送微喷装置
公开(公告)号：US20070293814A1
公开(公告)日：2007-12-20
申请号：US11518970
申请日：2006-09-11
申请人： Joseph Trautman , Ling-Kang Tong , Doran Donnelly
发明人： Joseph Trautman , Ling-Kang Tong , Doran Donnelly
IPC分类号： A61M37/00
CPC分类号： A61M37/0015 , A61M2037/0023 , A61M2037/0046
摘要： The present invention is a transdermal delivery microprojection assembly that includes a microprojection member secured to a retainer adapted for use with an impact applicator wherein at least a portion of the microprojections extend beyond a plane formed by the end of the retainer. The configuration allows a biocompatible coating containing a biologically active agent to be applied to the microprojection member after it is mounted on the retainer. The present invention minimizes the number of manufacturing steps that must be carried out under aseptic conditions to maintain sterility of the assembly after the coating is applied to the microprojection member.
摘要翻译：本发明是一种透皮递送微投影组件，其包括固定到适于与冲击施加器一起使用的保持器的微突出物构件，其中至少一部分微突出物延伸超过由保持器的端部形成的平面。该配置允许包含生物活性剂的生物相容性涂层在安装在保持器上之后被施加到微突出物构件。本发明使在无菌条件下必须执行的制造步骤的数量最小化，以在将涂层施加到微喷射构件之后维持组装的无菌性。

4. 发明授权

US08628542B2 Median lobe destruction apparatus and method 有权
标题翻译：中叶破坏装置及方法
公开(公告)号：US08628542B2
公开(公告)日：2014-01-14
申请号：US12979075
申请日：2010-12-27
申请人： Daniel Merrick , Joseph Catanese, III , Ling-Kang Tong , Floria Cheng , Michael Gearhart , Matthew McLean , Brian Y. Tachibana , Ben Thompson , James W. Niederjohn
发明人： Daniel Merrick , Joseph Catanese, III , Ling-Kang Tong , Floria Cheng , Michael Gearhart , Matthew McLean , Brian Y. Tachibana , Ben Thompson , James W. Niederjohn
IPC分类号： A61B17/10
CPC分类号： A61B17/3205 , A61B8/06 , A61B8/12 , A61B17/00234 , A61B17/0401 , A61B17/0469 , A61B17/064 , A61B17/32 , A61B17/3468 , A61B17/3478 , A61B17/42 , A61B18/1815 , A61B2017/00022 , A61B2017/00274 , A61B2017/0046 , A61B2017/00792 , A61B2017/00796 , A61B2017/00805 , A61B2017/00867 , A61B2017/0404 , A61B2017/0409 , A61B2017/0417 , A61B2017/0419 , A61B2017/0464 , A61B2017/0479 , A61B2017/0488 , A61B2017/06052 , A61B2017/06095 , A61B2017/2925 , A61B2018/00547 , A61B2018/1861 , A61B2018/1869
摘要： A system and associated method for altering or destroying tissues and anatomical or other structures in medical applications for the purpose of treating diseases or disorders. In one aspect, the system includes a device configured to deploy devices for altering the lobes of a prostate.
摘要翻译：用于在医疗应用中改变或破坏组织和解剖学或其他结构以用于治疗疾病或病症的系统和相关方法。在一个方面，该系统包括被配置为部署用于改变前列腺的叶的装置的装置。

5. 发明申请

US20110166564A1 Median Lobe Destruction Apparatus and Method 有权
标题翻译：中层破坏装置及方法
公开(公告)号：US20110166564A1
公开(公告)日：2011-07-07
申请号：US12979075
申请日：2010-12-27
申请人： Daniel Merrick , Joseph Catanese, III , Ling-Kang Tong , Floria Cheng , Michael Gearhart , Matthew McLean , Brian Y. Tachibana , Ben Thompson , James W. Niederjohn
发明人： Daniel Merrick , Joseph Catanese, III , Ling-Kang Tong , Floria Cheng , Michael Gearhart , Matthew McLean , Brian Y. Tachibana , Ben Thompson , James W. Niederjohn
IPC分类号： A61B18/18 , A61B17/00
CPC分类号： A61B17/3205 , A61B8/06 , A61B8/12 , A61B17/00234 , A61B17/0401 , A61B17/0469 , A61B17/064 , A61B17/32 , A61B17/3468 , A61B17/3478 , A61B17/42 , A61B18/1815 , A61B2017/00022 , A61B2017/00274 , A61B2017/0046 , A61B2017/00792 , A61B2017/00796 , A61B2017/00805 , A61B2017/00867 , A61B2017/0404 , A61B2017/0409 , A61B2017/0417 , A61B2017/0419 , A61B2017/0464 , A61B2017/0479 , A61B2017/0488 , A61B2017/06052 , A61B2017/06095 , A61B2017/2925 , A61B2018/00547 , A61B2018/1861 , A61B2018/1869
摘要： A system and associated method for altering or destroying tissues and anatomical or other structures in medical applications for the purpose of treating diseases or disorders. In one aspect, the system includes a device configured to deploy devices for altering the lobes of a prostate.
摘要翻译：用于在医疗应用中改变或破坏组织和解剖学或其他结构以用于治疗疾病或病症的系统和相关方法。在一个方面，该系统包括被配置为部署用于改变前列腺的叶的装置的装置。

6. 发明授权

US10130353B2 Flexible system for delivering an anchor 有权
公开(公告)号：US10130353B2
公开(公告)日：2018-11-20
申请号：US13538758
申请日：2012-06-29
申请人： Joseph Catanese, III , Floria Cheng , Theodore C. Lamson , Raul Macatangay , Matthew McLean , Thomas C. Ryan , Ling-Kang Tong , Brian Y. Tachibana
发明人： Joseph Catanese, III , Floria Cheng , Theodore C. Lamson , Raul Macatangay , Matthew McLean , Thomas C. Ryan , Ling-Kang Tong , Brian Y. Tachibana
IPC分类号： A61B17/10 , A61B17/04 , A61B17/064 , A61B17/02 , A61B17/00 , A61B17/06 , A61B1/00 , A61B90/00
摘要： A system and associated method for manipulating tissues and anatomical or other structures in medical applications for the purpose of treating diseases or disorders or other purposes. In one aspect, the system includes a delivery device including a flexible portion that is suited to access target anatomy. The flexibility of an elongate portion of the delivery device can be varied. Additionally, the delivery device can include structure that maintains the positioning of the delivery device in patient anatomy.

7. 发明申请

US20140005690A1 FLEXIBLE SYSTEM FOR DELIVERING AN ANCHOR 审中-公开
标题翻译：用于提供锚杆的柔性系统
公开(公告)号：US20140005690A1
公开(公告)日：2014-01-02
申请号：US13538758
申请日：2012-06-29
申请人： Joseph Catanese, III , Floria Cheng , Theodore C. Lamson , Raul Macatangay , Matthew McLean , Thomas C. Ryan , Ling-Kang Tong , Brian Y. Tachibana
发明人： Joseph Catanese, III , Floria Cheng , Theodore C. Lamson , Raul Macatangay , Matthew McLean , Thomas C. Ryan , Ling-Kang Tong , Brian Y. Tachibana
IPC分类号： A61B17/10
CPC分类号： A61B17/0401 , A61B1/00147 , A61B1/00183 , A61B17/0218 , A61B17/0644 , A61B2017/00274 , A61B2017/003 , A61B2017/00309 , A61B2017/00314 , A61B2017/00323 , A61B2017/00557 , A61B2017/00867 , A61B2017/00871 , A61B2017/00893 , A61B2017/00964 , A61B2017/0409 , A61B2017/0419 , A61B2017/0464 , A61B2017/06052 , A61B2017/0641 , A61B2017/0645 , A61B2017/0649 , A61B2090/037
摘要： A system and associated method for manipulating tissues and anatomical or other structures in medical applications for the purpose of treating diseases or disorders or other purposes. In one aspect, the system includes a delivery device including a flexible portion that is suited to access target anatomy. The flexibility of an elongate portion of the delivery device can be varied. Additionally, the delivery device can include structure that maintains the positioning of the delivery device in patient anatomy.
摘要翻译：用于在医疗应用中操纵组织和解剖结构或其他结构以用于治疗疾病或障碍或其它目的的系统和相关方法。在一个方面，该系统包括包括适于接近目标解剖结构的柔性部分的递送装置。递送装置的细长部分的柔性可以变化。另外，输送装置可以包括维持输送装置在患者解剖学中的定位的结构。

8. 发明申请

US20110160748A1 Median Lobe Band Implant Apparatus and Method 有权
标题翻译：中等腰带植入装置及方法
公开(公告)号：US20110160748A1
公开(公告)日：2011-06-30
申请号：US12979078
申请日：2010-12-27
申请人： Joseph Catanese, III , Brian Y. Tachibana , Matthew McLean , Daniel Merrick , Theodore C. Lamson , Ling-Kang Tong , James W. Niederjohn , Floria Cheng , Ben Thompson
发明人： Joseph Catanese, III , Brian Y. Tachibana , Matthew McLean , Daniel Merrick , Theodore C. Lamson , Ling-Kang Tong , James W. Niederjohn , Floria Cheng , Ben Thompson
IPC分类号： A61B17/10
CPC分类号： A61F2/04 , A61B17/00234 , A61B17/0401 , A61B17/0469 , A61B17/064 , A61B17/32 , A61B17/3468 , A61B17/3478 , A61B17/42 , A61B2017/00022 , A61B2017/00274 , A61B2017/0046 , A61B2017/00792 , A61B2017/00796 , A61B2017/00805 , A61B2017/00867 , A61B2017/0404 , A61B2017/0409 , A61B2017/0417 , A61B2017/0419 , A61B2017/0464 , A61B2017/0479 , A61B2017/0488 , A61B2017/06052 , A61B2017/06095 , A61B2017/2925 , A61B2018/00547
摘要： A system and associated method for manipulating tissues and anatomical or other structures in medical applications for the purpose of treating diseases or disorders or other purposes. In one aspect, the system includes a delivery device configured to deploy and implant devices for compressing, distracting and/or retracting the lobes of a prostate.
摘要翻译：用于在医疗应用中操纵组织和解剖结构或其他结构以用于治疗疾病或障碍或其它目的的系统和相关方法。一方面，该系统包括配置成部署和植入用于压缩，分散和/或缩回前列腺的瓣的装置的递送装置。

9. 发明申请

US20110060349A1 ANCHOR DELIVERY SYSTEM 有权
标题翻译：锚固输送系统
公开(公告)号：US20110060349A1
公开(公告)日：2011-03-10
申请号：US12852243
申请日：2010-08-06
申请人： Floria Cheng , Michael Gearhart , Andrew Johnston , Theodore C. Lamson , Matthew McLean , Daniel Merrick , Paul Suarez , Brian Y. Tachibana , Ben Thompson , Ling-Kang Tong , Joseph Catanese, III
发明人： Floria Cheng , Michael Gearhart , Andrew Johnston , Theodore C. Lamson , Matthew McLean , Daniel Merrick , Paul Suarez , Brian Y. Tachibana , Ben Thompson , Ling-Kang Tong , Joseph Catanese, III
IPC分类号： A61B17/10
CPC分类号： A61B17/0401 , A61B17/00234 , A61B17/0469 , A61B17/32 , A61B17/3468 , A61B17/3478 , A61B17/42 , A61B2017/00022 , A61B2017/00274 , A61B2017/0046 , A61B2017/00792 , A61B2017/00796 , A61B2017/00805 , A61B2017/0409 , A61B2017/0417 , A61B2017/0419 , A61B2017/0464 , A61B2017/0479 , A61B2017/0488 , A61B2017/06052 , A61B2017/06095 , A61B2017/2923 , A61B2018/00547
摘要： A system and associated method for manipulating tissues and anatomical or other structures in medical applications for the purpose of treating diseases or disorders or other purposes. In one aspect, the system includes a delivery device configured to deploy and implant anchor devices for such purposes.
摘要翻译：用于在医疗应用中操纵组织和解剖结构或其他结构以用于治疗疾病或障碍或其它目的的系统和相关方法。在一个方面，该系统包括被配置成部署和植入用于这些目的的锚定装置的输送装置。

10. 发明授权

US08529584B2 Median lobe band implant apparatus and method 有权
标题翻译：中轴带植入装置及方法
公开(公告)号：US08529584B2
公开(公告)日：2013-09-10
申请号：US12979078
申请日：2010-12-27
申请人： Joseph Catanese, III , Brian Y. Tachibana , Matthew McLean , Daniel Merrick , Theodore C. Lamson , Ling-Kang Tong , James Niederjohn , Floria Cheng , Ben Thompson
发明人： Joseph Catanese, III , Brian Y. Tachibana , Matthew McLean , Daniel Merrick , Theodore C. Lamson , Ling-Kang Tong , James Niederjohn , Floria Cheng , Ben Thompson
IPC分类号： A61B17/10
CPC分类号： A61F2/04 , A61B17/00234 , A61B17/0401 , A61B17/0469 , A61B17/064 , A61B17/32 , A61B17/3468 , A61B17/3478 , A61B17/42 , A61B2017/00022 , A61B2017/00274 , A61B2017/0046 , A61B2017/00792 , A61B2017/00796 , A61B2017/00805 , A61B2017/00867 , A61B2017/0404 , A61B2017/0409 , A61B2017/0417 , A61B2017/0419 , A61B2017/0464 , A61B2017/0479 , A61B2017/0488 , A61B2017/06052 , A61B2017/06095 , A61B2017/2925 , A61B2018/00547
摘要： A system and associated method for manipulating tissues and anatomical or other structures in medical applications for the purpose of treating diseases or disorders or other purposes. In one aspect, the system includes a delivery device configured to deploy and implant devices for compressing, distracting and/or retracting the lobes of a prostate.
摘要翻译：用于在医疗应用中操纵组织和解剖结构或其他结构以用于治疗疾病或障碍或其它目的的系统和相关方法。一方面，该系统包括配置成部署和植入用于压缩，分散和/或缩回前列腺的瓣的装置的递送装置。

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