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1. 发明申请

US20120253274A1 Medicament Delivery Device 有权
标题翻译：药物输送装置
公开(公告)号：US20120253274A1
公开(公告)日：2012-10-04
申请号：US13511295
申请日：2010-10-15
申请人： Martin Karlsson , Nils Ronquist
发明人： Martin Karlsson , Nils Ronquist
IPC分类号： A61M5/31
CPC分类号： A61M5/2448 , A61M5/2033 , A61M5/3155 , A61M5/31553 , A61M5/3156 , A61M5/31583
摘要： The present invention relates to a medicament delivery device comprising a distal housing part (12); a proximal housing part (10) into which a multi-chamber medicament container (14) is arranged and wherein said proximal housing part is arranged to be movable in relation to said distal housing part for mixing at least two substances arranged inside said container; a plunger rod (32) arranged to act on a distal stopper (34) in said medicament container, wherein a relative movement of said housing parts (10, 12) towards each other forces said distal stopper against the plunger rod in a proximal direction for mixing at least two substances arranged inside said container; a drive force unit (58, 74, 76, 78) capable of forcing said plunger rod (32) in the proximal direction for subsequent delivery of medicament from said medicament container; an activation member (80) slidably arranged through said distal housing part and releasably connected to the drive force unit; wherein said device further comprises a guide shell (24) one-way rotatable arranged in said distal housing part, wherein said guide shell is provided with threads (22) arranged to cooperate with corresponding threads (20) on said proximal housing, and wherein said guide shell and said plunger rod are arranged with guide members such that they are rotationally locked but slidable in relation to each other.
摘要翻译：本发明涉及一种药物输送装置，其包括远侧壳体部分（12）; 近端壳体部分（10），多室药物容器（14）布置在其中，并且其中所述近侧壳体部分布置成可相对于所述远端壳体部分移动，用于混合布置在所述容器内的至少两种物质; 柱塞杆（32），布置成作用在所述药物容器中的远端止动件（34）上，其中所述壳体部件（10,12）朝向彼此的相对运动迫使所述远端止动件沿近端方向抵靠柱塞杆混合布置在所述容器内的至少两种物质; 驱动力单元（58,74,76,78），其能够迫使所述柱塞杆（32）在近端方向上，用于随后从所述药物容器输送药物; 活动构件（80），其可滑动地布置成穿过所述远侧壳体部分并且可释放地连接到所述驱动力单元; 其中所述装置还包括导向壳（24），所述引导壳（24）单向旋转地布置在所述远端壳体部分中，其中所述引导壳设置有螺纹（22），所述螺纹布置成与所述近端壳体上的对应螺纹（20）配合，并且其中引导壳和所述柱塞杆布置有引导构件，使得它们被旋转地锁定，但可相对于彼此滑动。

2. 发明授权

US09005160B2 Medicament delivery device 有权
标题翻译：药物输送装置
公开(公告)号：US09005160B2
公开(公告)日：2015-04-14
申请号：US13511295
申请日：2010-10-15
申请人： Martin Karlsson , Nils Ronquist
发明人： Martin Karlsson , Nils Ronquist
IPC分类号： A61M37/00 , A61M5/24 , A61M5/20 , A61M5/315
CPC分类号： A61M5/2448 , A61M5/2033 , A61M5/3155 , A61M5/31553 , A61M5/3156 , A61M5/31583
摘要： A medicament delivery device includes a distal housing part; a proximal housing part in which a multi-chamber medicament container is arranged, with the proximal housing part movable relative to the distal housing part for mixing substances in the container; a plunger rod arranged to act on a stopper in the container, where movement of the housing parts toward each other forces the stopper against the plunger rod for mixing the substances in the container; a drive force unit for forcing the plunger rod for subsequent delivery of medicament; an activation member slidable through the distal housing part and releasably connected to the drive force unit; and a guide shell one-way rotatable in the distal housing part with threads that cooperate with threads on the proximal housing part. The guide shell and plunger rod have guide members such that they are rotationally locked but slidable in relation to each other.
摘要翻译：药物输送装置包括远端壳体部分; 近端壳体部分，其中布置有多腔药物容器，其中近侧壳体部分可相对于远端壳体部分移动，用于将物质混合在容器中; 柱塞杆，其布置成作用在容器中的止动件上，其中壳体部件相对于彼此的移动迫使止动件抵靠柱塞杆以混合容器中的物质; 用于迫使所述柱塞杆随后输送药物的驱动力单元; 激活构件，其可滑动地穿过所述远侧壳体部分并且可释放地连接到所述驱动力单元; 以及在所述远侧壳体部分中可旋转的导向壳，所述导向壳具有与近侧壳体部分上的螺纹配合的螺纹。导向壳和柱塞杆具有引导构件，使得它们被旋转地锁定，但可相对于彼此滑动。

3. 发明申请

US20120216805A1 Metered Liquid Droplet Inhaler 有权
标题翻译：计量液滴吸入器
公开(公告)号：US20120216805A1
公开(公告)日：2012-08-30
申请号：US13500915
申请日：2010-09-13
申请人： Lennart Brunnberg , Martin Karlsson , Nils Ronquist
发明人： Lennart Brunnberg , Martin Karlsson , Nils Ronquist
IPC分类号： A61M15/00
CPC分类号： A61M15/0065 , A61M5/2033 , A61M5/31525 , A61M5/31553 , A61M5/31583 , A61M11/007 , A61M11/06 , A61M15/0021 , A61M15/0066 , A61M15/0095 , A61M15/0096
摘要： A metered liquid droplet inhaling device includes a chassis; a holder releasably connected to the chassis; a container in the holder having a chamber for a composition, an opening for expelling the composition, and a piston; a dose knob accessible outside the chassis for setting a dose to be expelled by accumulating a rotational force; a power supply mechanism for converting the rotational force into an axial force applied to the piston; an activation device connected to the power supply mechanism; a mouth piece connected to the container holder and having a mouth engaging area and an air opening; a droplet generator arranged in the mouth piece and having a plurality of through passing orifices in fluid communication with the opening of the container and with the mouth piece; and a rotation damping member connected to the power supply mechanism for damping an initial pressure peak inside the container.
摘要翻译：计量液滴吸入装置包括底盘; 可释放地连接到所述底盘的保持器; 保持器中的容器具有用于组合物的室，用于排出组合物的开口和活塞; 剂量旋钮，可在底盘外部通过累积旋转力来设定要排出的剂量; 用于将旋转力转换成施加到活塞的轴向力的供电机构; 连接到所述电源机构的激活装置; 连接到容器保持器并具有口接合区域和空气开口的口部件; 液滴发生器布置在口部件中并且具有与容器的开口和嘴部流体连通的多个通过孔口; 以及连接到所述供电机构的用于阻尼所述容器内的初始压力峰值的旋转阻尼构件。

4. 发明授权

US09750900B2 Metered liquid droplet inhaler 有权
公开(公告)号：US09750900B2
公开(公告)日：2017-09-05
申请号：US13500915
申请日：2010-09-13
申请人： Lennart Brunnberg , Martin Karlsson , Nils Ronquist
发明人： Lennart Brunnberg , Martin Karlsson , Nils Ronquist
IPC分类号： A61M5/00 , A61M11/06 , A61M11/00 , A61M5/315 , A61M5/20 , A61M15/00
CPC分类号： A61M15/0065 , A61M5/2033 , A61M5/31525 , A61M5/31553 , A61M5/31583 , A61M11/007 , A61M11/06 , A61M15/0021 , A61M15/0066 , A61M15/0095 , A61M15/0096
摘要： A metered liquid droplet inhaling device includes a chassis; a holder releasably connected to the chassis; a container in the holder having a chamber for a composition, an opening for expelling the composition, and a piston; a dose knob accessible outside the chassis for setting a dose to be expelled by accumulating a rotational force; a power supply mechanism for converting the rotational force into an axial force applied to the piston; an activation device connected to the power supply mechanism; a mouth piece connected to the container holder and having a mouth engaging area and an air opening; a droplet generator arranged in the mouth piece and having a plurality of through passing orifices in fluid communication with the opening of the container and with the mouth piece; and a rotation damping member connected to the power supply mechanism for damping an initial pressure peak inside the container.

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