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    • 7. 发明申请
    • Synthesis of N-vinyl formamide
    • N-乙烯基甲酰胺的合成
    • US20050033089A1
    • 2005-02-10
    • US10789900
    • 2004-02-27
    • Eric BeckmanToby ChapmanCedrick FaveroChristopher CapelliHarold SwiftWilliam Carroll
    • Eric BeckmanToby ChapmanCedrick FaveroChristopher CapelliHarold SwiftWilliam Carroll
    • C07C231/12C07C231/14C07C233/03C07C233/05
    • C07C231/12C07C233/03C07C233/05
    • A process to produce N-vinylformamide includes the steps of: reacting hydroxyethyl formamide with a reactant comprising at least one cyclic anhydride group to form an ester, and dissociating the ester via heat in a thin film evaporation to synthesize N-vinylformamide and a compound comprising at least one diacid group, the N-vinylformamide separating from the diacid during the thin film evaporation. The reactant including at least one cyclic anhydride group can, for example, be succinic anhydride, maleic anhydride, phthalic anhydride, (2-docecen-1-yl)succinic anhydride, exo-3,6-epoxy-1,2,3,6 -tetrahydrophthalic anhydride or a polymer including at least one cyclic anhydride group. A process to produce N-vinylformamide comprises the steps of: mixing acetaldehyde, formamide and a source of anhydride in a single reaction vessel, reacting the acetaldehyde, formamide and the source of anhydride in the reaction vessel under pressure, dissociating an ester formed by a reaction between the source of anhydride and hydroxyethyl formamide formed in the reaction vessel to synthesize N-vinylformamide and a compound comprising at least one diacid group.
    • 制备N-乙烯基甲酰胺的方法包括以下步骤:使羟乙基甲酰胺与包含至少一个环状酸酐基团的反应物反应形成酯,并在薄膜蒸发中通过热解离酯以合成N-乙烯基甲酰胺和包含 至少一个二酸基团,在薄膜蒸发期间与二酸分离的N-乙烯基甲酰胺。 包括至少一个环状酸酐基团的反应物可以是例如琥珀酸酐,马来酸酐,邻苯二甲酸酐,(2-多烯-1-基)琥珀酸酐,外部-3,6-环氧-1,2,3, 6-四氢邻苯二甲酸酐或包含至少一个环状酸酐基团的聚合物。 制备N-乙烯基甲酰胺的方法包括以下步骤:将乙醛,甲酰胺和酸酐源在单个反应容器中混合,在压力下使乙醛,甲酰胺和酸酐源在反应容器中反应,使由 在反应容器中形成的酸酐源和羟乙基甲酰胺之间的反应合成N-乙烯基甲酰胺和包含至少一个二酸基团的化合物。
    • 8. 发明申请
    • Synthesis on N-vinyl formamide
    • N-乙烯基甲酰胺的合成
    • US20060025630A1
    • 2006-02-02
    • US11229869
    • 2005-09-19
    • Eric BeckmanTony ChapmanCedrick FaveroChristopher CapelliHarold Swift
    • Eric BeckmanTony ChapmanCedrick FaveroChristopher CapelliHarold Swift
    • C07C231/12
    • C07C231/12C07C233/03
    • A process to produce N-vinylformamide includes the steps of: reacting hydroxyethyl formamide with a reactant including at least one cyclic anhydride group to form an ester, and dissociating (or cracking) the ester to synthesize N-vinylformamide and a compound including at least one diacid group. The ester can be dissociated using heat. The reactant including at least one cyclic anhydride group can, for example, be succinic anhydride, maleic anhydride, phthalic anhydride, a polymer including at least one cyclic anhydride group, or a solid support to which at least one cyclic anhydride group is covalently tethered. Preferably, the cyclic anhydride is regenerated from the diacid formed in the synthesis of the ester by heating the diacid to dehydrate the diacid. The temperature required to dehydrate diacid groups is preferably higher than the temperature use to dissociate the ester.
    • 制备N-乙烯基甲酰胺的方法包括以下步骤:使羟乙基甲酰胺与包含至少一个环状酸酐基团的反应物反应形成酯,并使酯解离(或开裂)以合成N-乙烯基甲酰胺和包含至少一种 二酸组。 酯可以使用热分解。 包括至少一个环状酸酐基团的反应物可以是例如琥珀酸酐,马来酸酐,邻苯二甲酸酐,包含至少一个环状酸酐基团的聚合物或至少一个环状酸酐基团共价连接的固体载体。 优选地,通过加热二酸以脱水二酸,从酯合成中形成的二酸中再生环酐。 脱水二酸基团所需的温度优选高于解离酯的温度。