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1. 发明授权

US5980831A Support planar germanium waveguides for infrared evanescent-wave sensing 失效
标题翻译：支持平面锗波导，用于红外消逝波感测
公开(公告)号：US5980831A
公开(公告)日：1999-11-09
申请号：US874711
申请日：1997-06-13
申请人： Mark S. Braiman , Susan E. Plunkett , James J. Stone
发明人： Mark S. Braiman , Susan E. Plunkett , James J. Stone
IPC分类号： G01N21/55 , G01N21/00
CPC分类号： G01N21/552
摘要： We have fabricated miniature planar IR waveguides of thickness 30-50 .mu.m, consisting of 12-mm long, 2-mm wide strips of Ge supported on ZnS substrates. Evidence for efficient propagation of broadband IR light through these waveguides is provided by the presence of characteristic high and low frequency optical cut-offs of Ge; by the observation of an oscillatory interference pattern in the transmittance spectrum, which exhibits a dependence on waveguide thickness and propagation angle closely matching waveguide theory; and by the detection of strong evanescent-wave absorption from small (2 mm.sup.2) droplets of liquid, e.g. water, on the waveguide surface. As also predicted by theory, the surface sensitivity (detected light absorbance per unit area of sample-waveguide contact) was shown to increase as a function of incidence or bevel angle.
摘要翻译：我们制造了厚度为30-50微米的微型平面IR波导，由支撑在ZnS基底上的12英寸长，2毫米宽的Ge带组成。通过存在Ge的特征性高频和低频光学截止来提供宽带IR光通过这些波导的有效传播的证据; 通过观察透射光谱中的振荡干涉图案，其显示出与波导理论紧密匹配的波导厚度和传播角度的依赖性; 并且通过检测来自小（2mm 2）液体液滴的强的ev逝波吸收。水，在波导表面。也可以通过理论预测，表面灵敏度（样品 - 波导接触的每单位面积的检测光吸收率）显示随着入射角或斜角角度的增加而增加。

2. 发明授权

US5355425A Light coupling device for optical fibers 失效
标题翻译：用于光纤的光耦合装置
公开(公告)号：US5355425A
公开(公告)日：1994-10-11
申请号：US940647
申请日：1992-09-04
申请人： Mark S. Braiman , Roy E. Jonas
发明人： Mark S. Braiman , Roy E. Jonas
IPC分类号： G01N21/55 , G02B6/38 , G02B6/42 , G02B6/26
CPC分类号： G02B6/4296 , G01N21/552 , G02B6/4204 , G02B6/4298 , G02B6/3814
摘要： A light source to optical fiber coupling device comprising: a diamond coupler, a light source located at an end of the diamond coupler, an optical fiber having an end which is adjacent the other end of the diamond coupler, the optical fiber being in optical coupling relation with the diamond coupler.
摘要翻译：一种光纤到光纤耦合器件，包括：金刚石耦合器，位于金刚石耦合器端部的光源，具有与金刚石耦合器的另一端相邻的端部的光纤，光纤处于光耦合与金刚石耦合器的关系。

3. 发明授权

US09249508B2 Bromine-sensitized solar photolysis of carbon dioxide 有权
标题翻译：二氧化碳的溴敏太阳光解
公开(公告)号：US09249508B2
公开(公告)日：2016-02-02
申请号：US13609512
申请日：2012-09-11
申请人： Mark S. Braiman
发明人： Mark S. Braiman
IPC分类号： C23C18/12 , C01B31/10 , C23C16/48 , B01D53/62 , C07D305/04 , C23C16/26 , C23C18/14
CPC分类号： C23C16/26 , B01D53/62 , C01B32/05 , C01B32/336 , C07D321/00 , C23C16/48 , C23C16/482 , C23C18/1204 , C23C18/1208 , C23C18/1245 , C23C18/14 , Y02P20/134 , Y10T428/2991 , Y10T428/2993 , Y10T442/2992
摘要： There is described a process for depositing carbon on a surface, comprising, while contacting a mixture of CO2 and Br2 with a polar substrate presenting apposed surfaces, exposing a sufficient area of said mixture in the region of said apposed surfaces to light of sufficient intensity and frequency to result in deposition of carbon on at least some of said apposed surfaces. Other embodiments are also described.
摘要翻译：描述了一种在表面上沉积碳的方法，包括在将CO 2和Br 2的混合物与呈现呈现表面的极性底物接触的同时，将所述表面区域中的所述混合物的足够面积暴露于足够强度的光，频率导致碳沉积在所述至少一些所述表面上。还描述了其它实施例。

4. 发明授权

US10190212B2 Bromine-sensitized solar photolysis of carbon dioxide 有权
公开(公告)号：US10190212B2
公开(公告)日：2019-01-29
申请号：US15853892
申请日：2017-12-25
申请人： Mark S. Braiman
发明人： Mark S. Braiman
IPC分类号： C23C16/26 , C23C16/48 , B01D53/62 , C23C18/12 , C23C18/14 , C07D321/00 , C01B32/05 , C01B32/336
摘要： There is described a process for depositing carbon on a surface, comprising, while contacting a mixture of CO2 and Br2 with a polar substrate presenting apposed surfaces, exposing a sufficient area of said mixture in the region of said apposed surfaces to light of sufficient intensity and frequency to result in deposition of carbon on at least some of said apposed surfaces. Other embodiments are also described.

5. 发明授权

US5719195A Treatment of psoriasis with 11-cis-retinoic acid 失效
标题翻译：用11-顺 - 视黄酸治疗牛皮癣
公开(公告)号：US5719195A
公开(公告)日：1998-02-17
申请号：US435804
申请日：1995-05-05
申请人： Mark S. Braiman
发明人： Mark S. Braiman
IPC分类号： A61K8/67 , A61K31/07 , A61K31/20 , A61K31/203 , A61Q19/00
CPC分类号： C07C403/14 , A61K31/203 , A61K8/671 , A61Q19/00 , C07C403/20 , A61K2800/75 , A61K2800/81 , C07B2200/09 , C07C2101/16
摘要： A particular uncommon isomer of retinoic acid (namely 11-cis-retinoic acid, or neotretinoin) is useful in treating conditions involving abnormal cellular differentiation and hyperproliferation, such as psoriasis. A new method of synthesizing this isomer, in quantities that has allowed it to be compared therapeutically with the more commonly available all-trans and 13-cis isomers, is presented. As measured on the inventor's own psoriasis-affected skin, topical treatment with 11-cis-retinoic acid is much more efficacious in reducing symptoms and has substantially reduced side effects, as compared to topical treatment with the other isomers. A single application of a 0.001% neotretinoin cream to psoriasis lesions leads within 48 hours to substantial amelioration of associated dermatological symptoms, including itching, scaling, bleeding, and abnormal appearance. Continued application leads to complete remission, and replacement of lesions by skin that is indistinguishable from surrounding healthy tissue, without any noticeable irritation, erythema, or other problematic side effects. A less efficacious but more easily-implemented version of the same invention employs ultraviolet or blue-light irradiation of a commercially-available gel containing tretinoin as a means of effecting partial conversion of the tretinoin to neotretinoin, prior to application of the gel to psoriasis-affected areas of skin.
摘要翻译：视黄酸特别不常见的异构体（即11-顺 - 视黄酸或新维甲酸）可用于治疗涉及异常细胞分化和过度增殖的病症，如牛皮癣。提出了一种合成该异构体的新方法，其数量使其能够与更常用的全反式和13顺式异构体进行治疗比较。根据发明人自己的牛皮癣影响的皮肤，与使用其它异构体的局部治疗相比，用11-顺式视黄酸进行局部治疗比减少症状更有效，并且具有显着降低的副作用。对银屑病病变的单次应用是0.001％的新维A酸霜在48小时内导致相关皮肤病症状的显着改善，包括瘙痒，结垢，出血和异常外观。继续应用导致完全缓解，并且与周围健康组织不可区分的皮肤替换病变，没有明显的刺激，红斑或其它有问题的副作用。在将凝胶应用于银屑病之前，相同发明的不太有效但更容易实现的版本使用含有维A酸的市售凝胶的紫外线或蓝光照射作为实现维A酸至部分转化为新维甲酸的方法，受影响的皮肤区域。

6. 发明授权

US09885111B2 Bromine-sensitized solar photolysis of carbon dioxide 有权
公开(公告)号：US09885111B2
公开(公告)日：2018-02-06
申请号：US15011677
申请日：2016-02-01
申请人： Mark S. Braiman
发明人： Mark S. Braiman
IPC分类号： C23C16/26 , C23C16/48 , B01D53/62 , C23C18/12 , C23C18/14 , C07D321/00 , C01B32/05 , C01B32/336
CPC分类号： C23C16/26 , B01D53/62 , C01B32/05 , C01B32/336 , C07D321/00 , C23C16/48 , C23C16/482 , C23C18/1204 , C23C18/1208 , C23C18/1245 , C23C18/14 , Y02P20/134 , Y10T428/2991 , Y10T428/2993 , Y10T442/2992
摘要： There is described a process for depositing carbon on a surface, comprising, while contacting a mixture of CO2 and Br2 with a polar substrate presenting apposed surfaces, exposing a sufficient area of said mixture in the region of said apposed surfaces to light of sufficient intensity and frequency to result in deposition of carbon on at least some of said apposed surfaces. Other embodiments are also described.

7. 发明授权

US07517968B2 Rapid and inexpensive method for the purification of proteorhodopsin 有权
标题翻译：快速而廉价的纯化蛋白质视紫红质的方法
公开(公告)号：US07517968B2
公开(公告)日：2009-04-14
申请号：US10886782
申请日：2004-07-07
申请人： Mark S. Braiman , Ranga Partha
发明人： Mark S. Braiman , Ranga Partha
IPC分类号： C07K14/00 , A23J1/00
CPC分类号： C07K14/195 , C07K14/705
摘要： A method for purifying a membrane protein is disclosed which includes providing a test sample potentially including a target membrane protein; adding incremental amounts of a precipitating agent to the test sample to form one or more mixtures; and treating the one or more mixtures under conditions effective to obtain precipitated, purified target membrane protein if present in the test sample.
摘要翻译：公开了一种纯化膜蛋白的方法，其包括提供潜在包括靶膜蛋白的测试样品; 向测试样品中加入增量的沉淀剂以形成一种或多种混合物; 以及在有效获得沉淀的纯化的靶膜蛋白（如果存在于测试样品中）的条件下处理该一种或多种混合物。

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