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1. 发明授权

US5904658A Hand-held materials tester 失效
标题翻译：手持材料测试仪
公开(公告)号：US5904658A
公开(公告)日：1999-05-18
申请号：US916277
申请日：1997-08-22
申请人： Mark Q. Niederauer , Robert P. Wilkes , George M. Niederauer , Sabine Cristante , Steven F. Cline , Robert A. Tynmann
发明人： Mark Q. Niederauer , Robert P. Wilkes , George M. Niederauer , Sabine Cristante , Steven F. Cline , Robert A. Tynmann
IPC分类号： G01N3/48 , A61B5/103 , G01N3/40 , G01N3/42 , G01N33/483
CPC分类号： A61B5/4514 , A61B5/0053 , A61B5/103 , A61B5/442 , G01N3/42 , G01N33/4833 , A61B2560/0252 , A61B2560/0285 , A61B2562/0261 , A61B5/4528
摘要： A handheld materials testing device is provided for measuring compressive properties of a material, preferably articular cartilage in vivo. The device is computer-controlled and provides a readout indicative of the desired compressive property, which in the case of bodily tissue, may be indicative of the state of health of the tissue. The device does not require precise perpendicular alignment and is preferably capable of compensating for force applied by the user against the tissue.
摘要翻译：提供了用于测量材料的压缩性能的手持式材料测试装置，优选在体内的关节软骨。该装置是计算机控制的并且提供指示期望的压缩性质的读数，其在身体组织的情况下可以指示组织的健康状态。该装置不需要精确的垂直对准，并且优选地能够补偿使用者施加在组织上的力。

2. 发明授权

US08419696B2 System and method for delivering reduced pressure to subcutaneous tissue 有权
公开(公告)号：US08419696B2
公开(公告)日：2013-04-16
申请号：US12562220
申请日：2009-09-18
申请人： Robert P. Wilkes
发明人： Robert P. Wilkes
IPC分类号： A61M1/00
CPC分类号： A61M1/0023 , A61M1/0031 , A61M1/0033 , A61M1/0049 , A61M1/0084 , A61M1/0092 , A61M2205/7509 , A61M2205/7518
摘要： A reduced pressure treatment system includes a first fluid pathway in communication with a reduced pressure source and a second fluid pathway. The system includes a reduced pressure manifold having a substantially gas impermeable barrier and at least one outer conduit defining a lateral edge of an interior region. The outer conduit and the substantially gas impermeable barrier enclose a portion of the interior region. The outer conduit is in fluid communication with one of the first and second fluid pathways. The outer conduit has at least one opening in fluid communication with the interior region. An inner conduit is at least partially disposed within the interior region and is in fluid communication with another of the first and second fluid pathways. The inner conduit has at least one opening in fluid communication with the interior region.

3. 发明授权

US08444611B2 Negative pressure wound treatment dressing 有权
标题翻译：负压伤口治疗敷料
公开(公告)号：US08444611B2
公开(公告)日：2013-05-21
申请号：US10895700
申请日：2004-07-21
申请人： Robert P. Wilkes , Teryl Blane Sanders
发明人： Robert P. Wilkes , Teryl Blane Sanders
IPC分类号： A61F13/00 , A61F13/06
CPC分类号： A61F13/069 , A61F13/067 , A61F2013/00174 , A61F2013/00519 , A61M1/0088 , A61M27/00
摘要： A wound treatment dressing for applying negative pressure wound therapy to a wound on an extremity, such as on the heel of a foot. The dressing includes a fluid manifold positioned within a fenestrated drape to form a contoured occlusive wrapping. A contoured porous pad is placed adjacent or within the wound, and is covered by the occlusive wrapping. Flexible tubing is attached to or through a port to allow fluid communication of negative pressure to the contoured pad from a source of negative pressure. The negative pressure is communicated from the source, through the tube, through the fluid manifold, and through the fenestrations of the occlusive wrapping, to the wound. The fluid manifold conducts the negative pressure from a position away from the wound site to the contoured pad at the wound site.
摘要翻译：一种伤口治疗敷料，用于对肢体上的伤口（例如脚后跟）施加负压伤口治疗。敷料包括定位在开窗的盖布中的流体歧管，以形成轮廓闭合包裹。轮廓多孔垫被放置在伤口附近或内部，并被闭塞包裹覆盖。柔性管连接到端口或通过端口，以允许从负压源将流体连通到轮廓衬垫。负压从源，通过管，通过流体歧管，并通过封闭包装的开窗传递到伤口。流体歧管将负压从远离伤口部位的位置传导到伤口处的轮廓垫。

4. 发明申请

US20070166817A1 System and Method for Applying Reduced Pressure to Cell Culture 有权
标题翻译：将压力降低到细胞培养的系统和方法
公开(公告)号：US20070166817A1
公开(公告)日：2007-07-19
申请号：US11624017
申请日：2007-01-17
申请人： Robert P. Wilkes , Amy K. McNulty , Kristine Kieswetter , Teri D. Feely , Marisa Schmidt
发明人： Robert P. Wilkes , Amy K. McNulty , Kristine Kieswetter , Teri D. Feely , Marisa Schmidt
IPC分类号： C12M1/12
CPC分类号： C12M41/40 , C12M25/04 , C12M35/04
摘要： A method and system for culturing cells, having a substantially airtight enclosure configured to culture cells. The method and system also have a first conduit configured to provide a reduced pressure to the substantially airtight enclosure and a second conduit configured to provide a culture media to the substantially airtight enclosure.
摘要翻译：用于培养细胞的方法和系统，其具有构造成培养细胞的基本上气密的外壳。所述方法和系统还具有构造成向基本上气密的外壳提供减压的第一导管和被配置为向基本上气密的外壳提供培养基的第二导管。

5. 发明授权

US07981668B2 System and method for applying reduced pressure to cell culture 有权
标题翻译：用于减轻细胞培养的系统和方法
公开(公告)号：US07981668B2
公开(公告)日：2011-07-19
申请号：US11624017
申请日：2007-01-17
申请人： Robert P. Wilkes , Amy K. McNulty , Kristine Kieswetter , Teri D. Feeley , Marisa Schmidt
发明人： Robert P. Wilkes , Amy K. McNulty , Kristine Kieswetter , Teri D. Feeley , Marisa Schmidt
IPC分类号： C12M3/00
CPC分类号： C12M41/40 , C12M25/04 , C12M35/04
摘要： A method and system for culturing cells, having a substantially airtight enclosure configured to culture cells. The method and system also have a first conduit configured to provide a reduced pressure to the substantially airtight enclosure and a second conduit configured to provide a culture media to the substantially airtight enclosure.
摘要翻译：用于培养细胞的方法和系统，其具有构造成培养细胞的基本上气密的外壳。所述方法和系统还具有构造成向基本上气密的外壳提供减压的第一导管和被配置为向基本上气密的外壳提供培养基的第二导管。

6. 发明申请

US20100069886A1 SYSTEM AND METHOD FOR DELIVERING REDUCED PRESSURE TO SUBCUTANEOUS TISSUE 有权
标题翻译：将减压压力递送至少量组织的系统和方法
公开(公告)号：US20100069886A1
公开(公告)日：2010-03-18
申请号：US12562220
申请日：2009-09-18
申请人： Robert P. Wilkes
发明人： Robert P. Wilkes
IPC分类号： A61M27/00 , A61M1/00 , A61F13/00
CPC分类号： A61M1/0023 , A61M1/0031 , A61M1/0033 , A61M1/0049 , A61M1/0084 , A61M1/0092 , A61M2205/7509 , A61M2205/7518
摘要： A reduced pressure treatment system includes a first fluid pathway in communication with a reduced pressure source and a second fluid pathway. The system includes a reduced pressure manifold having a substantially gas impermeable barrier and at least one outer conduit defining a lateral edge of an interior region. The outer conduit and the substantially gas impermeable barrier enclose a portion of the interior region. The outer conduit is in fluid communication with one of the first and second fluid pathways. The outer conduit has at least one opening in fluid communication with the interior region. An inner conduit is at least partially disposed within the interior region and is in fluid communication with another of the first and second fluid pathways. The inner conduit has at least one opening in fluid communication with the interior region
摘要翻译：减压处理系统包括与减压源和第二流体通路连通的第一流体通路。该系统包括具有基本不透气屏障的减压歧管和限定内部区域的侧边缘的至少一个外导管。外导管和基本不透气的屏障围绕内部区域的一部分。外导管与第一和第二流体路径中的一个流体连通。外导管具有与内部区域流体连通的至少一个开口。内部管道至少部分地设置在内部区域内并与第一和第二流体路径中的另一个流体连通。内导管具有与内部区域流体连通的至少一个开口

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