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1. 发明授权

US5346504A Intraluminal manipulator with a head having articulating links 失效
标题翻译：具有头部具有关节连杆的管腔内机械手
公开(公告)号：US5346504A
公开(公告)日：1994-09-13
申请号：US979501
申请日：1992-11-19
申请人： Mark Ortiz , Joseph Paraschac
发明人： Mark Ortiz , Joseph Paraschac
IPC分类号： A61B17/00 , A61B17/28 , A61B19/00 , A61B1/26
CPC分类号： A61B34/70 , A61B17/00234 , A61B2034/715
摘要： The present invention is directed towards an intraluminal manipulator which extends into a lumen and is operable to position and manipulate the tissue surrounding the lumen as necessary during a medical procedure. The manipulator includes a head, a handle and an interconnecting shaft. A pair of cables extend through the shaft and interconnect the head and handle. Movement of a trigger provided by the handle moves the head, which is formed by a series of articulated links, between generally straight and arched configurations. Movement of the trigger in one direction moves the head from a straightened to an arched configuration, while movement in an opposite direction moves the head from the arched to the straightened configuration. When placed in the straight configuration, the head is insertable into and removable from the lumen. When the head is in the arched configuration, it engages the walls surrounding and defining the lumen and can thereafter be used to manipulate the tissue. A fiber optic bundle is provided to allow remote visualization of the lumen, and an expandable balloon is used to provide a better frictional engagement between the head and the tissue defining the lumen.
摘要翻译：本发明涉及一种管腔内操纵器，其延伸到内腔中并且可操作以在医疗过程期间根据需要定位和操纵围绕管腔的组织。操纵器包括头部，把手和互连轴。一对电缆延伸穿过轴并连接头部和手柄。由手柄提供的触发器的移动将由一系列铰接链节形成的头部移动到大体上直的和拱形的构型之间。触发器在一个方向上的移动将头部从直线移动到拱形构型，而沿相反方向的移动将头部从拱形移动到矫直构型。当放置成直线构型时，头部可插入内腔并从内腔中移除。当头部处于拱形构型时，其与围绕并限定内腔的壁接合，并且此后可用于操纵组织。提供光纤束以允许内窥镜的远程可视化，并且可扩张气囊用于在限定内腔的头部和组织之间提供更好的摩擦接合。

2. 发明申请

US20100256630A1 IRREVERSIBLE ELECTROPORATION (IRE) FOR ESOPHAGEAL DISEASE 审中-公开
标题翻译：不可逆电气（IRE）用于食管疾病
公开(公告)号：US20100256630A1
公开(公告)日：2010-10-07
申请号：US12755517
申请日：2010-04-07
申请人： William C. Hamilton, JR. , Mark Ortiz
发明人： William C. Hamilton, JR. , Mark Ortiz
IPC分类号： A61B18/14
CPC分类号： A61B18/1492 , A61B2018/0016 , A61B2018/00214 , A61B2018/0022 , A61B2018/00488 , A61B2018/00613 , A61B2018/1465
摘要： A method for treating Barrett's esophagus and esophageal cancer by using non-thermal electroporation energy to ablate diseased portions of the esophagus which, in effect, prevents stomach acids and other fluids from entering the esophagus thereby alleviating continued deterioration of the esophagus and allows the columnar cells in the lining of the esophagus to assume their normal physical characteristics and functions and.
摘要翻译：一种通过使用非热电穿孔能来消融食道的病变部分来治疗巴雷特食管和食管癌的方法，其实际上防止胃酸和其它流体进入食道，从而减轻食管的持续恶化，并允许柱状细胞在食管的衬里中承担其正常的身体特征和功能。

3. 再颁专利

USRE40377E1 Means and method of replacing a heart valve in a minimally invasive manner 有权
标题翻译：以微创方式更换心脏瓣膜的方法和方法
公开(公告)号：USRE40377E1
公开(公告)日：2008-06-10
申请号：US10863862
申请日：2004-06-07
申请人： Warren P. Williamson, IV , Paul A. Spence , George T. Christakis , Mark Ortiz
发明人： Warren P. Williamson, IV , Paul A. Spence , George T. Christakis , Mark Ortiz
IPC分类号： A61F2/24
摘要： A heart valve can be replaced using minimally invasive methods which include a sutureless sewing cuff that and a fastener delivery tool that holds the cuff against the patient's tissue while delivering fasteners to attach the cuff to the tissue from the inside out. The tool stores a plurality of fasteners and is self-contained whereby a fastener is delivered and placed all from inside a vessel. The fasteners are self-forming whereby they do not need an anvil to be formed. Anchor elements are operated from outside the patient's body to cinch a prosthesis to an anchoring cuff of the valve body. The cuff is releasably mounted on the tool and the tool holds the cuff against tissue and drives the fastener through the cuff and the tissue before folding over the legs of the fastener whereby secure securement between the cuff and the tissue is assured. Fasteners are placed and formed whereby fasteners are located continuously throughout the entire circumference of the cuff. A minimally invasive surgical method is disclosed, and a method and tool are disclosed for repairing abdominal aortic aneurysms in a minimally invasive manner. Fasteners that are permanently deformed during the process of attaching the cuff are disclosed as are fasteners that are not permanently deformed during the attaching process.
摘要翻译：可以使用微创方法来替换心脏瓣膜，所述方法包括无缝线缝合套，以及紧固件递送工具，其将袖带保持抵靠患者组织，同时递送紧固件以将袖带从内向外附接到组织。该工具存储多个紧固件并且是独立的，由此紧固件全部从容器内部输送和放置。紧固件是自成型的，由此它们不需要形成砧座。锚杆元件从患者身体外部操作，将假体固定到阀体的锚定箍。袖带可释放地安装在工具上，并且工具将袖带保持抵靠组织，并且在折叠紧固件的腿部之前通过袖口和组织驱动紧固件，从而确保袖带和组织之间的牢固固定。紧固件被放置和形成，由此紧固件连续地位于袖带的整个圆周上。公开了一种微创手术方法，并且公开了一种以微创方式修复腹主动脉瘤的方法和工具。在附接袖带的过程中永久变形的紧固件公开为在附接过程中不会永久变形的紧固件。

4. 发明申请

US20070239177A1 Method for instrument insertion through a body orifice 有权
标题翻译：仪器通过体孔插入的方法
公开(公告)号：US20070239177A1
公开(公告)日：2007-10-11
申请号：US11394174
申请日：2006-03-31
申请人： Michael Stokes , Thomas Albrecht , Mark Ortiz , Mark Zeiner , Andrew Zwolinski , Frederick Shelton
发明人： Michael Stokes , Thomas Albrecht , Mark Ortiz , Mark Zeiner , Andrew Zwolinski , Frederick Shelton
IPC分类号： A61B17/04
CPC分类号： A61B17/0469
摘要： A method for inserting an instrument through a natural orifice. The instrument has a low profile orientation and a deployed orientation which is larger than the size of the natural orifice through which it is to be inserted. The method is achieved by coupling the instrument to an endoscope and placing the instrument in its low profile orientation, insetting the endoscope and the instrument through a natural orifice to a target position within a body while the instrument is in its low profile orientation, actuating the instrument to it is deployed orientation, and returning the instrument to its low profile orientation and withdrawing the instrument from the body through the natural orifice.
摘要翻译：一种通过天然孔口插入仪器的方法。仪器具有低轮廓取向和展开方向，其大于被插入的自然孔的尺寸。该方法通过将仪器连接到内窥镜并将仪器置于其低轮廓取向来实现，其将内窥镜和仪器通过自然孔口内插到身体内的目标位置，同时仪器处于低度方向，致动仪器部署方向，并将仪器返回到其低调方向，并将仪器从身体通过自然孔抽出。

5. 发明申请

US20070232850A1 ENDOSCOPIC ANCILLARY ATTACHMENT DEVICES 有权
标题翻译：内窥镜附件装置
公开(公告)号：US20070232850A1
公开(公告)日：2007-10-04
申请号：US11278016
申请日：2006-03-30
申请人： Michael Stokes , Mark Ortiz , Frederick Shelton
发明人： Michael Stokes , Mark Ortiz , Frederick Shelton
IPC分类号： A61B1/00
CPC分类号： A61B1/018 , A61B1/0014 , A61B1/005
摘要： Methods and devices are provided for attaching one or more ancillary devices to an endoscope. The ancillary device can be any device that is used in conjunction with endoscopic procedures, such as, by way of non-limiting example, an accessory channel, tube, or sleeve, an indwelling tube or feeding tube, and surgical tools such as graspers, snares, etc. The ancillary device(s) can be positioned adjacent to and along side an external surface of an insertion portion of an endoscope for inserting into a body lumen, and one or more attachment devices can be used to mate the ancillary device(s) to the endoscope at one or more attachment locations. In use, the attachment device(s) will allow the ancillary device to move in coordination with the endoscope, thus allowing the endoscope and the ancillary device(s) to be introduced and guided through a tortuous pathway. In certain exemplary embodiments, the attachment device(s) can be configured to prevent radial movement, i.e., twisting, of the ancillary device relative to the endoscope, yet allow axial sliding of the ancillary device relative to the endoscope.
摘要翻译：提供了用于将一个或多个辅助装置附接到内窥镜的方法和装置。辅助装置可以是与内窥镜程序结合使用的任何装置，例如通过非限制性示例，附件通道，管或套管，留置管或进料管，以及外科手术工具，例如抓紧器，圈套等。辅助装置可以被定位成与内窥镜的插入部分的外表面相邻并且沿着侧面插入到体腔中，并且可以使用一个或多个附接装置来配合辅助装置（ s）到一个或多个附接位置处的内窥镜。在使用中，附接装置将允许辅助装置与内窥镜协调地移动，从而允许将内窥镜和辅助装置引入并引导通过曲折的路径。在某些示例性实施例中，附接装置可以构造成防止辅助装置相对于内窥镜的径向运动，即扭转，而允许辅助装置相对于内窥镜的轴向滑动。

6. 发明申请

US20070114261A1 Surgical stapler with a bendable end effector 有权
标题翻译：具有可弯曲末端执行器的手术吻合器
公开(公告)号：US20070114261A1
公开(公告)日：2007-05-24
申请号：US11287525
申请日：2005-11-23
申请人： Mark Ortiz , Michael Stokes
发明人： Mark Ortiz , Michael Stokes
IPC分类号： A61B17/10
CPC分类号： A61B17/07207 , A61B17/064 , A61B2017/003 , A61B2017/0641 , A61B2017/07214 , A61B2017/07221
摘要： A surgical stapler having a selectively bendable end effector is provided. A staple holding jaw of the end effector is coupled to another jaw for grasping tissue to be stapled. The stapler can adapted to drive staples into tissue having a pattern conforming with the selected shape of the end effector. In particular, the end effector can be adapted to drive staples in a linear pattern when the end effector orients staples in a substantially linear configuration. The end effector can also be adapted to drive staples in a non linear pattern when the end effector orients staples in a non linear configuration. Methods of stapling tissue with a stapler having a bendable end effector are also discussed.
摘要翻译：提供具有可选择性弯曲的端部执行器的手术吻合器。端部执行器的钉子保持钳口联接到另一个钳口以用于抓取待装订的组织。订书机可以适应于将订书钉驱动到具有符合所选择的端部执行器形状的图案的组织中。特别地，末端执行器可以适于在末端执行器以大体上线性的构型定向缝合时以线性图案驱动钉。端部执行器还可以适于在端部执行器以非线性配置引导订书钉时以非线性图案驱动订书钉。还讨论了用具有可弯曲端部执行器的订书机装订组织的方法。

7. 发明申请

US20070043384A1 Method and apparatus for endoscopically performing gastric reduction surgery in a single pass 有权
标题翻译：在单次通过内窥镜下进行胃减压手术的方法和装置
公开(公告)号：US20070043384A1
公开(公告)日：2007-02-22
申请号：US11206297
申请日：2005-08-18
申请人： Mark Ortiz , Michael Stokes
发明人： Mark Ortiz , Michael Stokes
IPC分类号： A61B17/10
CPC分类号： A61B17/0684 , A61B17/00234 , A61B17/0401 , A61B17/0644 , A61B2017/00296 , A61B2017/0496 , A61B2017/2905 , A61B2017/306 , A61F5/0086
摘要： A gastric reduction apparatus provides for the secure attachment of multiple fasteners into the gastric wall, the fasteners being linked with a flexible member in a manner permitting the reduction of the effective size of an individual's stomach. The apparatus includes an applicator head including a proximal end and a distal end. The applicator head of the gastric reduction apparatus includes a cavity shaped and dimensioned for receiving tissue. A fastener attachment mechanism is positioned within the cavity for access to tissue that is pulled within the cavity and the fastener attachment mechanism includes a plurality of fasteners.
摘要翻译：减胃装置提供将多个紧固件牢固地附接到胃壁中，紧固件以允许减小个体胃的有效尺寸的方式与柔性构件连接。该装置包括一个包括近端和远端的涂抹头。胃减压装置的涂抹头包括形状和尺寸适于接收组织的空腔。紧固件附接机构定位在腔体内，用于进入被抽吸在腔内的组织，并且紧固件附接机构包括多个紧固件。

8. 发明申请

US20070038237A1 ELECTROACTIVE POLYMER-BASED LUMEN TRAVERSING DEVICE 有权
标题翻译：基于聚合物的基于聚合物的光电转移装置
公开(公告)号：US20070038237A1
公开(公告)日：2007-02-15
申请号：US11161262
申请日：2005-07-28
申请人： Jeffrey Swayze , Mark Ortiz
发明人： Jeffrey Swayze , Mark Ortiz
IPC分类号： A61M29/00
CPC分类号： A61B1/0053 , A61B1/00156
摘要： Methods and devices are provided for traversing a lumen of a tubular body part, such as the large or small intestine, the colon, the bladder, the stomach, etc. In an exemplary embodiment, the methods and devices utilize electroactive polymers that are selectively actuated to move a device through a lumen.
摘要翻译：提供了用于穿过诸如大肠或小肠，结肠，膀胱，胃等的管状主体部分的内腔的方法和装置。在示例性实施例中，所述方法和装置利用选择性地致动的电活性聚合物通过管腔移动设备。

9. 发明申请

US20070032822A1 Fasteners for use with gastic restriction 有权
标题翻译：紧固件用于胶垫限制
公开(公告)号：US20070032822A1
公开(公告)日：2007-02-08
申请号：US11197529
申请日：2005-08-05
申请人： Mark Ortiz , Michael Stokes , David Plescia
发明人： Mark Ortiz , Michael Stokes , David Plescia
IPC分类号： A61B17/08
CPC分类号： A61B17/064 , A61B17/00234 , A61B17/0401 , A61B17/0644 , A61B2017/00867 , A61B2017/0412 , A61B2017/0414 , A61B2017/042 , A61B2017/0422 , A61B2017/0427 , A61B2017/0437 , A61B2017/0464 , A61B2017/0496 , A61B2017/086 , A61F5/0086
摘要： A fastener is used during endoscopic procedures in which a suture is used in creating a predefined pouch through tissue apposition within the stomach. The fastener includes a fastener body having a tissue anchor for selectively securing the fastener body to tissue. The fastener body also includes a connection aperture shaped and dimensioned for passage of a suture therethrough.
摘要翻译：在内窥镜过程中使用紧固件，其中缝合线用于通过胃内的组织配合产生预定义的袋。紧固件包括具有组织锚固件的紧固件主体，用于将紧固件主体选择性地固定到组织。紧固件主体还包括形状和尺寸用于通过缝合线的连接孔。

10. 发明申请

US20070027356A1 ELECTROACTIVE POLYMER ACTUATED GASTRIC BAND 有权
标题翻译：电动聚合物致动胶带
公开(公告)号：US20070027356A1
公开(公告)日：2007-02-01
申请号：US11161268
申请日：2005-07-28
申请人： Mark Ortiz
发明人： Mark Ortiz
IPC分类号： A61F2/00
CPC分类号： A61F5/0066 , A61F5/0053
摘要： Methods and devices are provided for remotely adjusting a size of a gastric band disposed around a patient's stomach. In one exemplary embodiment, a gastric band is provided having a first end and a second end that mate to one another to encircle a stomach. A latch mechanism can be formed on the band, and at least one actuator can be coupled to the latch mechanism and it can be adapted to expand and contract the latch mechanism when energy is applied thereto to adjust a diameter of the band. In one exemplary embodiment, the actuator(s) is an electroactive polymer actuator.
摘要翻译：提供了用于远程调整设置在患者胃周围的胃带的大小的方法和装置。在一个示例性实施例中，提供胃带，其具有彼此配合以包围胃的第一端和第二端。可以在带上形成闩锁机构，并且至少一个致动器可以联接到闩锁机构，并且当能量施加到闩锁机构以调节带的直径时，闩锁机构可以适于扩展和收缩闩锁机构。在一个示例性实施例中，致动器是电活性聚合物致动器。

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