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1. 发明授权

US06200957B1 Antagonists of gonadotropin releasing hormone 失效
公开(公告)号：US06200957B1
公开(公告)日：2001-03-13
申请号：US09115497
申请日：1998-07-14
申请人： Mark Goulet , Wallace T. Ashton , Lin Chu , Michael H. Fisher , Peter Lin , Mitree M. Ponpipom , Matthew J. Wyvratt , Narindar N. Girotra , Jonathan Young
发明人： Mark Goulet , Wallace T. Ashton , Lin Chu , Michael H. Fisher , Peter Lin , Mitree M. Ponpipom , Matthew J. Wyvratt , Narindar N. Girotra , Jonathan Young
IPC分类号： C07D20910
CPC分类号： C07D401/12 , C07D401/14 , C07D413/14 , C07D487/08
摘要： There are disclosed compounds of formula (I) and pharmaceutically acceptable salts thereof which are useful as antagonists of GnRH and as such may be useful for the treatment of a variety of sex-hormone related and other conditions in both men and women.

2. 发明申请

US20060035935A1 Acylated piperidine derivatives as melanocortin-4 receptor agonists 审中-公开
公开(公告)号：US20060035935A1
公开(公告)日：2006-02-16
申请号：US11239721
申请日：2005-09-30
申请人： Mark Goulet , Ravi Nargund , Iyassu Sebhat , Feroze Ujjainwalla , Thomas Walsh , Daniel Warner , Zhixiong Ye , Jonathan Young , Raman Bakshi
发明人： Mark Goulet , Ravi Nargund , Iyassu Sebhat , Feroze Ujjainwalla , Thomas Walsh , Daniel Warner , Zhixiong Ye , Jonathan Young , Raman Bakshi
IPC分类号： A61K31/454 , C07D417/02 , C07D413/02 , C07D403/02 , C07D401/02
CPC分类号： C07D491/08 , A61K31/445 , C07D211/62 , C07D211/64 , C07D401/06 , C07D401/14 , C07D413/06 , C07D413/14
摘要： Certain novel 4-substituted N-acylated piperidine derivatives are agonists of the human melanocortin receptor(s) and, in particular, are selective agonists of the human melanocortin-4 receptor (MC-4R). They are therefore useful for the treatment, control, or prevention of diseases and disorders responsive to the activation of MC-4R, such as obesity, diabetes, sexual dysfunction, including erectile dysfunction and female sexual dysfunction.

3. 发明申请

US20070043015A1 Phenyl pyrrolidine ether tachykinin receptor antagonists 失效
标题翻译：苯基吡咯烷醚速激肽受体拮抗剂
公开(公告)号：US20070043015A1
公开(公告)日：2007-02-22
申请号：US10572444
申请日：2004-09-24
申请人： Robert DeVita , Peter Lin , Sander Mills , Jonathan Young
发明人： Robert DeVita , Peter Lin , Sander Mills , Jonathan Young
IPC分类号： A61K31/5377 , A61K31/496 , A61K31/454 , A61K31/4439 , A61K31/422 , A61K31/4178 , A61K31/4025 , A61K31/40 , C07D403/02 , C07D405/02 , C07D413/02
CPC分类号： C07D207/08 , C07D401/04 , C07D401/06 , C07D403/10 , C07D403/12 , C07D405/04 , C07D413/06 , C07D417/04 , C07D471/04 , C07D513/04
摘要： The present invention is directed to certain phenyl pyrrolidine ether compounds which are useful as neurokinin-1 (NK-1) receptor antagonists, and inhibitors of tachykinin and in particular substance P. The invention is also concerned with pharmaceutical formulations comprising these compounds as active ingredients and the use of the compounds and their formulations in the treatment of certain disorders, including emesis, depression, and anxiety.
摘要翻译：本发明涉及某些可用作神经激肽-1（NK-1）受体拮抗剂的苯基吡咯烷醚化合物，以及速激肽抑制剂，特别是物质P。本发明还涉及包含这些化合物作为活性成分的药物制剂以及化合物及其制剂在治疗某些疾病（包括呕吐，抑郁和焦虑）中的用途。

4. 发明申请

US20050026915A1 2-Aminoquinoline compounds 失效
标题翻译： 2-氨基喹啉化合物
公开(公告)号：US20050026915A1
公开(公告)日：2005-02-03
申请号：US10496615
申请日：2002-11-22
申请人： Robert DeVita , Lehua Chang , Danny Chaung , MyLe Hoang , JinLong Jiang , Peter Lin , Andreas Sailer , Jonathan Young
发明人： Robert DeVita , Lehua Chang , Danny Chaung , MyLe Hoang , JinLong Jiang , Peter Lin , Andreas Sailer , Jonathan Young
IPC分类号： C07D215/38 , A61K31/403 , A61K31/407 , A61K31/439 , A61K31/47 , A61K31/4709 , A61K31/496 , A61K31/4995 , A61K31/5377 , A61K31/54 , A61K31/55 , A61P1/14 , A61P1/16 , A61P3/00 , A61P3/04 , A61P3/06 , A61P3/10 , A61P7/00 , A61P7/10 , A61P9/00 , A61P9/10 , A61P9/12 , A61P13/12 , A61P15/00 , A61P19/02 , A61P21/00 , A61P25/02 , A61P25/08 , A61P25/14 , A61P25/16 , A61P25/18 , A61P25/22 , A61P25/24 , A61P25/28 , A61P25/30 , A61P35/00 , A61P43/00 , C07D215/22 , C07D215/227 , C07D401/04 , C07D401/12 , C07D401/14 , C07D405/04 , C07D405/14 , C07D413/14 , C07D417/04 , C07D417/12 , C07D417/14 , C07D453/00 , C07D471/08 , C07D487/08 , C07D487/10 , C07D491/04 , C07D491/08 , C07D495/10 , A61K31/541 , C07D413/02 , C07D417/02 , C07
CPC分类号： C07D215/227 , C07D401/04 , C07D401/12 , C07D401/14 , C07D405/14 , C07D413/14 , C07D417/04 , C07D417/14 , C07D491/04 , C07D495/10
摘要： The present invention is concerned with compounds of the general Formula I: and pharmaceutically acceptable salts thereof, which are useful as melanin concentrating hormone receptor antagonists, particularly MCH-1R antagonists. As such, compounds of the present invention are useful for the treatment or prevention of obesity or eating disorders associated with excessive food intake and complications thereof, osteoarthritis, certain cancers, AIDS wasting, cachexia, frailty (particularly in elderly), mental disorders stress, cognitive disorders, sexual function, reproductive function, kidney function, locomotor disorders, attention deficit disorder (ADD), substance abuse disorders and dyskinesias, Huntington's disease, epilepsy, memory function, and spinal muscular atrophy. Compounds of formula I may therefore be used in the treatment of these conditions, and in the manufacture of a medicament useful in treating these conditions. Pharmaceutical formulations comprising one of the compounds of formula (I) as an active ingredient are disclosed, as are processes for preparing these compounds.
摘要翻译：本发明涉及通式I的化合物及其药学上可接受的盐，其可用作黑色素浓缩激素受体拮抗剂，特别是MCH-1R拮抗剂。因此，本发明的化合物可用于治疗或预防与食物过量摄取及其并发症，骨关节炎，某些癌症，艾滋病消瘦，恶病质，虚弱（特别是老年人）相关的肥胖或进食障碍，精神障碍压力，认知障碍，性功能，生殖功能，肾功能，运动障碍，注意力缺陷障碍（ADD），药物滥用障碍和运动障碍，亨廷顿病，癫痫，记忆功能和脊髓性肌肉萎缩。因此，式I化合物可用于治疗这些病症，以及制备用于治疗这些病症的药物。作为制备这些化合物的方法，公开了包含式（I）化合物之一作为活性成分的药物制剂。

5. 发明申请

US20120043070A1 Magnetic Slip Retention for Downhole Tool 审中-公开
标题翻译：井下工具磁滑保留
公开(公告)号：US20120043070A1
公开(公告)日：2012-02-23
申请号：US13285440
申请日：2011-10-31
申请人： Patrick J. Zimmerman , David Ward , Jonathan Young
发明人： Patrick J. Zimmerman , David Ward , Jonathan Young
IPC分类号： E21B31/06
CPC分类号： E21B33/129 , E21B23/06
摘要： A downhole tool, such as a packer or liner hanger, has a mandrel on which slips are disposed for engaging a surrounding tubular downhole. When the tool is being run in or out of the hole, at least one magnetic component magnetically retains the slip adjacent the mandrel so the slip can be held away from the surrounding tubular. When the tool is set downhole, the initial magnetic retention can be broken, and the slips can be moved away from the mandrel to engage the surface of the surrounding tubular.
摘要翻译：诸如封隔器或衬管悬挂器的井下工具具有心轴，在其上设有滑动件用于与周围的管状井下接合。当工具进出孔时，至少一个磁性部件磁性地将滑动件保持在心轴附近，使得滑动件能够远离周围的管状部件。当工具设置在井下时，可以破坏初始磁保持，并且滑动件可以移动远离心轴以接合周围管的表面。

6. 发明申请

US20100247050A1 MODULAR NETWORK CONNECTION EQUIPMENT 有权
标题翻译：模块化网络连接设备
公开(公告)号：US20100247050A1
公开(公告)日：2010-09-30
申请号：US12517728
申请日：2007-12-06
申请人： Peter Ejvinsson , Jakob Bioje , Viktor Holmqvist , Hans Nyström , Jonathan Young , Rickard Guslavsson , Ola Skogsfors , Niclas Sonesson , Stefan Tagenfalk
发明人： Peter Ejvinsson , Jakob Bioje , Viktor Holmqvist , Hans Nyström , Jonathan Young , Rickard Guslavsson , Ola Skogsfors , Niclas Sonesson , Stefan Tagenfalk
IPC分类号： G02B6/00 , H05K13/00
CPC分类号： H04L12/2805 , H05K5/0021 , Y10T29/49117
摘要： An apparatus for connecting user equipment to a broadband network includes a chassis having attachment points for connection to a supporting surface and a guide that permits entry of a communication cable. A cable termination unit may be mounted on the chassis such that a cable that is led through the guide can be connected and provided with a termination to which functional connections can be made. A cover may be mounted on the chassis in such a way as to be removable and reattachable to allow access to the chassis. The chassis may include mounting points for connecting at least one functional module to the communication cable and for allowing different communication functions to be provided to user equipment that is connected to the network via the apparatus.
摘要翻译：用于将用户设备连接到宽带网络的装置包括具有用于连接到支撑表面的附接点的底盘和允许通信电缆进入的引导件。电缆终端单元可以安装在底盘上，使得通过引导件引导的电缆可以被连接并且设置有能够进行功能连接的终端。盖子可以以可拆卸的方式安装在底盘上，并且可重新连接以允许进入底盘。底盘可以包括用于将至少一个功能模块连接到通信电缆的安装点，并且允许将不同的通信功能提供给经由设备连接到网络的用户设备。

7. 发明申请

US20100243232A1 Magnetic Slip Retention for Downhole Tool 有权
标题翻译：井下工具磁滑保留
公开(公告)号：US20100243232A1
公开(公告)日：2010-09-30
申请号：US12409661
申请日：2009-03-24
申请人： Patrick J. Zimmerman , David Ward , Jonathan Young
发明人： Patrick J. Zimmerman , David Ward , Jonathan Young
IPC分类号： E21B33/129 , E21B33/12
CPC分类号： E21B33/129 , E21B23/06
摘要： A downhole tool, such as a packer or liner hanger, has a mandrel on which slips are disposed for engaging a surrounding tubular downhole. When the tool is being run in or out of the hole, at least one magnetic component magnetically retains the slip adjacent the mandrel so the slip can be held away from the surrounding tubular. When the tool is set downhole, the initial magnetic retention can be broken, and the slips can be moved away from the mandrel to engage the surface of the surrounding tubular.
摘要翻译：诸如封隔器或衬管悬挂器的井下工具具有心轴，在其上设有滑动件用于与周围的管状井下接合。当工具进出孔时，至少一个磁性部件磁性地将滑动件保持在心轴附近，使得滑动件能够远离周围的管状部件。当工具设置在井下时，可以破坏初始磁保持，并且滑动件可以移动远离心轴以接合周围管的表面。

8. 发明授权

US07620182B2 QKD with classical bit encryption 失效
标题翻译： QKD与经典位加密
公开(公告)号：US07620182B2
公开(公告)日：2009-11-17
申请号：US10577625
申请日：2004-02-13
申请人： Audrius Berzanskis , Jonathan Young
发明人： Audrius Berzanskis , Jonathan Young
IPC分类号： H04K1/00 , H04L9/00
CPC分类号： H04L9/0858 , H04L9/065
摘要： A method for enhancing the security of a quantum key distribution (QKD) system having QKD stations Alice and Bob. The method includes encrypting key bits generated by a true random number generator (TRNG) and sent to a polarization or phase modulator to encode weak optical pulses as qubits to be shared between Alice and Bob. Key bit encryption is achieved by using a shared password and a stream cipher. Bob obtains at least a subset of the original key bits used by Alice by utilizing the same stream cipher and the shared password.
摘要翻译：一种用于增强具有QKD站Alice和Bob的量子密钥分发（QKD）系统的安全性的方法。该方法包括对由真实随机数发生器（TRNG）生成的密钥进行加密，并将其发送到偏振或相位调制器以将弱光脉冲编码为在Alice和Bob之间共享的量子位。密钥位加密通过使用共享密码和流密码来实现。 Bob通过利用相同的流密码和共享密码获得Alice使用的原始密钥位的至少一个子集。

9. 发明授权

US07597552B2 Vehicle heater and controls therefor 有权
标题翻译：车辆加热器及其控制
公开(公告)号：US07597552B2
公开(公告)日：2009-10-06
申请号：US11329113
申请日：2006-01-11
申请人： Jonathan Young , Douglas Thompson Paul , Angelo Paccone
发明人： Jonathan Young , Douglas Thompson Paul , Angelo Paccone
IPC分类号： F23M9/06
CPC分类号： B60H1/2209 , B60H1/2206 , F23N3/082 , F23N5/203 , F23N2023/04 , F23N2023/08 , F23N2027/10 , F23N2031/10 , F23N2033/08 , F23N2041/14
摘要： A heater for a liquid has a combustion chamber, a jacket for the liquid extending about the combustion chamber and a burner head assembly connected to the combustion chamber. The burner head assembly includes a housing having a burner mounted thereon and a hollow interior. A control module and a fan are mounted in the hollow interior, the fan being connected to an electric motor. A compressor and a fuel pump are mounted on the housing and are operatively connected to the electric motor. The control module may include controls for exercising components of the heater prior to combustion, thereby verifying operation of these components. Preferably there is a speed control for the motor, such as a closed loop speed control which regulates motor speed and accordingly output of the heater. Preferably there is a backup system using a lookup table in the event that the closed loop speed control fails. Also preferably there is provision for monitoring flame sensor functionality by providing an indicator light which mirrors operation of the flame sensor. The heater may have a selective soft start for the coolant pump which operates only when required so as to reduce unnecessary chatter on the motor relay. A system is also provided for distinguishing true overcurrent faults from overcurrents arising from voltage changes during starting of the vehicle engine. Reignition algorithms are provided to restart the burner in the event of flame sputters caused, for example, by fuel bubbles, but shut off the heater in the event that the fuel is truly cut off.
摘要翻译：用于液体的加热器具有燃烧室，用于围绕燃烧室延伸的液体的护套和连接到燃烧室的燃烧器头组件。燃烧器头组件包括具有安装在其上的燃烧器和中空内部的壳体。控制模块和风扇安装在中空内部，风扇连接到电动机。压缩机和燃料泵安装在壳体上并且可操作地连接到电动机。控制模块可以包括用于在燃烧之前锻炼加热器的部件的控制，从而验证这些部件的操作。优选地，存在用于电动机的速度控制，例如调节电动机速度并因此输出加热器的闭环速度控制。优选地，在闭环速度控制失败的情况下，存在使用查找表的备份系统。还优选地，通过提供反映火焰传感器的操作的指示灯来监视火焰传感器功能。加热器可以具有用于仅在需要时操作的冷却剂泵的选择性软启动，以便减少马达继电器上的不必要的颤动。还提供一种系统，用于区分真实的过电流故障与车辆发动机启动期间电压变化引起的过电流。提供重燃算法以在例如由燃料气泡导致的火焰喷溅器的情况下重新启动燃烧器，但是在燃料被真正切断的情况下关闭加热器。

10. 发明申请

US20090198789A1 VIDEOGAME LOCALIZATION USING LANGUAGE PACKS 有权
标题翻译：使用语言包的视频本地化
公开(公告)号：US20090198789A1
公开(公告)日：2009-08-06
申请号：US12023991
申请日：2008-01-31
申请人： Jonathan Young , Antonio Vargas Garcia
发明人： Jonathan Young , Antonio Vargas Garcia
IPC分类号： G06F15/167
CPC分类号： A63F13/77 , A63F13/10 , A63F13/424 , A63F2300/209 , A63F2300/552
摘要： A code library, or “language interface pack” library, is provided that can be integrated into a video game to detect new localizations of the video game dynamically, and to locate and load the most appropriate localized resources depending on user preferences and available localized game content. If no localized content is available in the preferred language, a fallback system ensures that the game always receives the location of existing game content in another language.
摘要翻译：提供了一个代码库或“语言界面包”库，可以将其集成到视频游戏中，动态地检测视频游戏的新本地化，并根据用户偏好和可用的本地化游戏定位并加载最合适的本地化资源内容。如果没有本地化的内容可用于首选语言，则后备系统确保游戏总是以另一种语言接收现有游戏内容的位置。

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