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1. 发明授权

US5221485A Purification of X-ray contrast agent, magnetic resonance imaging agent, or radiopharmaceuticals using reverse osmosis 失效
标题翻译：使用反渗透法纯化X射线造影剂，磁共振成像剂或放射性药物
公开(公告)号：US5221485A
公开(公告)日：1993-06-22
申请号：US956440
申请日：1992-10-02
申请人： Mark E. Bosworth , Thomas J. Dunn , Warren E. Hall , Richard G. Johnson , Mills T. Kneller , Youlin Lin , Rebecca A. Wallace , David H. White , David M. Wong
发明人： Mark E. Bosworth , Thomas J. Dunn , Warren E. Hall , Richard G. Johnson , Mills T. Kneller , Youlin Lin , Rebecca A. Wallace , David H. White , David M. Wong
IPC分类号： A61K49/04 , B01D61/02 , C07C231/24 , C07C237/46
CPC分类号： B01D61/025 , A61K49/0433 , C07C231/24 , C07C237/46
摘要： The use of reverse osmosis as an alternative or substitute method for the purification of a crude diagnostic agent. X-ray contrast agent, magnetic resonance imaging agent, or radiopharmaceuticals are purified by passing through a cross-linked reverse osmosis membrane.
摘要翻译：使用反渗透作为纯化粗制诊断剂的替代方法或替代方法。通过交联反渗透膜纯化X射线造影剂，磁共振成像剂或放射性药剂。

2. 发明授权

US5160437A Purification of crude Ioversol using reverse osmosis 失效
标题翻译：使用反渗透纯化原油
公开(公告)号：US5160437A
公开(公告)日：1992-11-03
申请号：US801233
申请日：1991-12-03
申请人： Mark E. Bosworth , Thomas J. Dunn , Warren E. Hall , Richard G. Johnson , Mills T. Kneller , Youlin Lin , Rebecca A. Wallace , David H. White , David M. Wong
发明人： Mark E. Bosworth , Thomas J. Dunn , Warren E. Hall , Richard G. Johnson , Mills T. Kneller , Youlin Lin , Rebecca A. Wallace , David H. White , David M. Wong
IPC分类号： A61K49/04 , B01D61/02 , C07C231/24 , C07C237/46
CPC分类号： B01D61/025 , A61K49/0433 , C07C231/24 , C07C237/46
摘要： The use of reverse osmosis as an alternative or substitute method for the purification of a crude diagnostic agent. In the purification process a crude Ioversol solution is contacted with a cross-linked membrane under pressure, forcing the low molecular weight impurities within the crude Ioversol solution through the membrane pores and retaining Ioversol molecules.
摘要翻译：使用反渗透作为纯化粗制诊断剂的替代方法或替代方法。在纯化过程中，粗制的Ioversol溶液在压力下与交联膜接触，迫使粗的Ioversol溶液中的低分子量杂质通过膜孔并保留Ioversol分子。

3. 发明授权

US5089125A Chromatography column with sealing arrangement 失效
标题翻译：色谱柱与密封布置
公开(公告)号：US5089125A
公开(公告)日：1992-02-18
申请号：US481937
申请日：1990-02-20
申请人： Robert L. Hart , David M. Wong
发明人： Robert L. Hart , David M. Wong
IPC分类号： B01D15/08 , G01N30/60
CPC分类号： B01D15/22 , G01N30/6004
摘要： The present invention relates to chromatography column for process scale high performance purification, which has high stability and structural integrity regardless of the internal diameter or operating pressures. The chromatography column according to the present invention includes a sealing arrangement which enables the production of internally leak proof chromatography columns having large internal diameters at relatively low cost. The present invention also relates to the seal for the chromatography column.
摘要翻译：本发明涉及用于工艺规模高性能纯化的色谱柱，其具有高稳定性和结构完整性，而与内径或操作压力无关。根据本发明的色谱柱包括密封装置，其能够以相对低的成本生产具有大内径的内部防漏色谱柱。本发明还涉及色谱柱的密封。

4. 发明授权

US4991633A Sanitary packaging system 失效
标题翻译：卫生包装系统
公开(公告)号：US4991633A
公开(公告)日：1991-02-12
申请号：US473072
申请日：1990-01-31
申请人： David M. Wong
发明人： David M. Wong
IPC分类号： B65B55/04 , B65B31/00
CPC分类号： B65B31/00
摘要： A sanitary packaging system and method of using the same for the packaging of a sanitary product comprising a sanitary housing portion, a product bag, a sliding adjustment tube and a product tube. The product tube extends inside the sanitary housing portion and is flexibly attached to the sliding adjustment tube to which the product bag is attached. The sanitary product under pressure passes through the product tube, sliding adjustment tube and into the product bag to complete packaging. Sanitized air is blown through the sanitary housing enclosure to create a positive pressure therein, whereby in the case of a leak within the product bag, sliding adjustment tube or product entry tube, sanitary product leaks outwardly therefrom rather than allowing contaminates to be pulled inwardly and contaminate said sanitized product.
摘要翻译：一种卫生包装系统及其使用方法，用于包装卫生产品，包括卫生外壳部分，产品袋，滑动调节管和产品管。产品管在卫生间的内部延伸，并且柔性地附着到产品袋所附着的滑动调节管上。卫生产品在压力下通过产品管，滑动调节管，并进入产品包装完成包装。消毒空气吹过卫生间外壳，在其中产生正压，由此在产品袋，滑动调节管或产品入口管内泄漏的情况下，卫生产品向外泄漏，而不是允许污染物向内拉，污染所述消毒产品。

5. 发明授权

US4833329A System for generating and containerizing radioisotopes 失效
标题翻译：用于生成和集装放射性同位素的系统
公开(公告)号：US4833329A
公开(公告)日：1989-05-23
申请号：US123586
申请日：1987-11-20
申请人： Randall H. Quint , Richard F. Swenson , David M. Wong
发明人： Randall H. Quint , Richard F. Swenson , David M. Wong
IPC分类号： G21F5/015 , G21G4/08
CPC分类号： G21G4/08 , G21G1/0005 , Y10T137/86204 , Y10T137/87981
摘要： A system for eluting a daughter radioisotope from a parent radioisotope and containerizing the resultant eluate in an evacuated container having a rubber stopper, providing for delivery of eluant from a reservoir through a tube to a generator containing the parent radioisotope, for venting of the reservoir to atmosphere via a tube, and for delivery of eluate from the generator via a tube to a tubular needle pierced through the stopper, with a cam-controlled hinged pinch plate for pinching the tubes closed.
摘要翻译：一种用于从母体放射性同位素洗脱雌性放射性同位素并将所得洗脱液集装在具有橡胶塞的真空容器中的系统，其将洗涤剂从储存器通过管输送到含有母体放射性同位素的发生器，用于将储存器排出通过管将气体从发生器输送到穿过止动器的管状针上，用凸轮控制的铰链夹紧板将管子夹紧。

6. 发明授权

US07163031B2 Automated dispensing system and associated method of use 失效
标题翻译：自动点胶系统及相关使用方法
公开(公告)号：US07163031B2
公开(公告)日：2007-01-16
申请号：US10867918
申请日：2004-06-15
申请人： Kevin Graves , Andrew Williams , Andrew M. Schadt , David M. Wong
发明人： Kevin Graves , Andrew Williams , Andrew M. Schadt , David M. Wong
IPC分类号： B65B1/04
CPC分类号： B65B3/003 , G21F5/015
摘要： An automated bulk dispensing system and a method of use including selectively receiving a predetermined amount of radioactive liquid from a second container into a third container, selectively receiving a predetermined amount of nonradioactive liquid from a first container into a fourth container or directly into the third container depending on whether kits or multi-dose containers of medicine are desired. Preferably, this is for nuclear pharmaceuticals. Displacement mechanisms that are connected to the third container and fourth container are for mixing and dispensing liquid. There is at least one control valve, preferably three control valves, which are each controlled by drive mechanisms. The mixed liquid from the third container can be transferred to a recipient container. There is also a gas vent and bubble detector to eliminate bubbles with a processor that is also utilized to control the displacement mechanisms and the drive mechanisms.
摘要翻译：一种自动批量分配系统和使用方法，包括从第二容器选择性地接收预定量的放射性液体到第三容器中，选择性地将预定量的非放射性液体从第一容器接收到第四容器中或直接进入第三容器这取决于是否需要药盒或多剂量药物。优选地，这是用于核药物。连接到第三容器和第四容器的位移机构用于混合和分配液体。至少有一个控制阀，最好是三个控制阀，它们都由驱动机构控制。来自第三容器的混合液体可以被转移到容器中。还有一个排气口和气泡检测器，用于处理器消除气泡，处理器也用于控制位移机构和驱动机构。

7. 发明授权

US5227139A Sanitary sampling system 失效
标题翻译：卫生抽样系统
公开(公告)号：US5227139A
公开(公告)日：1993-07-13
申请号：US724222
申请日：1991-07-01
申请人： David M. Wong
发明人： David M. Wong
IPC分类号： B01L3/14 , B65D51/00
CPC分类号： B01L3/50825 , B65D51/002 , Y10S435/809 , Y10S436/81
摘要： A sanitary sampling system for attachment to a tube portion of a fluid containing enclosure. The sanitary sampling system is comprised of a rigid stem portion for attachment to the tube portion of the fluid enclosure, a stopper portion having a lower portion for insertion into the rigid stem portion and tube portion, a disk-shaped orifice plate fitting for placement on the upper surface of the stopper portion and an adjustable clamp for adjustment around the stem portion, orifice plate fitting and stopper portions of the sanitary sampling system. The sanitary sampling system is designed to enable the stem portion, stopper portion and orifice plate fitting to interlock to form an air-tight and leak-free seal when the adjustable clamp is tightened.
摘要翻译：卫生采样系统，用于连接到流体容纳外壳的管部分。卫生采样系统包括用于附接到流体外壳的管部分的刚性杆部分，具有用于插入到刚性杆部分和管部分中的下部的止动部分，用于放置在刚性杆部分上的盘形孔板配件止动部分的上表面和用于调节卫生采样系统的杆部分，孔板配件和止动部分周围的可调节夹具。卫生采样系统被设计成使得当可调节夹紧器被紧固时，杆部分，止动部分和孔板配件互锁以形成气密且无泄漏的密封。

8. 发明授权

US5137628A Sealing arrangement for a chromatography column 失效
标题翻译：色谱柱的密封排列
公开(公告)号：US5137628A
公开(公告)日：1992-08-11
申请号：US627173
申请日：1990-12-14
申请人： Robert L. Hart , David M. Wong
发明人： Robert L. Hart , David M. Wong
IPC分类号： B01D15/08 , G01N30/60
CPC分类号： B01D15/08 , B01D15/22 , G01N30/6026
摘要： The present invention relates to chromatography column for process scale high performance purification, which has high stability and structural integrity regardless of the internal diameter or operating pressures. The chromatography column according to the present invention includes a sealing arrangement which enables the production of internally leak proof chromatography columns having large internal diameters at relatively low cost. The present invention also relates to the seal for the chromatography column.
摘要翻译：本发明涉及用于工艺规模高性能纯化的色谱柱，其具有高稳定性和结构完整性，而与内径或操作压力无关。根据本发明的色谱柱包括密封装置，其能够以相对低的成本生产具有大内径的内部防漏色谱柱。本发明还涉及色谱柱的密封。

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