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1. 发明授权

US5582168A Apparatus and methods for measuring characteristics of biological tissues and similar materials 失效
标题翻译：用于测量生物组织和类似材料特性的装置和方法
公开(公告)号：US5582168A
公开(公告)日：1996-12-10
申请号：US7584
申请日：1993-01-22
申请人： Mark A. Samuels , Scott W. Patterson , Jonathan A. Eppstein , Nai T. Yu , Sven-Erik Bursell
发明人： Mark A. Samuels , Scott W. Patterson , Jonathan A. Eppstein , Nai T. Yu , Sven-Erik Bursell
IPC分类号： A61B3/10 , A61B3/117 , A61B3/12 , A61B3/14 , A61B5/00
CPC分类号： A61B5/1455 , A61B3/1173 , A61B5/14532
摘要： Apparatus and methods for characterizing biological tissues and other turbid media with normalization that serves to compensate for the effects of scattering, reflectance, and absorption are disclosed.
摘要翻译：公开了用于表征用于补偿散射，反射和吸收的影响的归一化的生物组织和其他混浊介质的装置和方法。

2. 发明授权

US5203328A Apparatus and methods for quantitatively measuring molecular changes in the ocular lens 失效
标题翻译：用于定量测量OCARAR镜中分子变化的方法和方法
公开(公告)号：US5203328A
公开(公告)日：1993-04-20
申请号：US731533
申请日：1991-07-17
申请人： Mark A. Samuels , Scott W. Patterson , Jonathan A. Eppstein , Nai T. Yu , Sven-Erik Bursell
发明人： Mark A. Samuels , Scott W. Patterson , Jonathan A. Eppstein , Nai T. Yu , Sven-Erik Bursell
IPC分类号： A61B3/10 , A61B3/117 , A61B3/12 , A61B3/14 , A61B5/00
CPC分类号： A61B5/1455 , A61B3/1173 , A61B5/14532
摘要： Apparatus and methods for noninvasively diagnosing diabetes mellitus, the prediabetic condition, and cataracts in the human (or other) body are disclosed. Diagnoses are made by illuminating ocular lens tissue with a narrow-band light source at a selected wavelength, detecting the backscattered radiation intensity at the peak of the fluorescent response, and normalizing the detected value with the intensity of its Rayleigh component. Measurements provided in this manner can be used as improved indicators of the presence or absence of certain diseases or conditions.
摘要翻译：公开了用于非侵入性诊断糖尿病，前列腺疾病和人（或其他）身体中的白内障的装置和方法。通过用选定波长的窄带光源照射眼透镜组织来进行诊断，检测在荧光响应的峰值处的反向散射辐射强度，并用其瑞利分量的强度归一化检测值。以这种方式提供的测量可以用作某些疾病或病症的存在或不存在的改进指标。

3. 发明授权

US4836207A Method and apparatus to monitor cholesterol levels with photon correlation spectroscopy 失效
标题翻译：用光子相关光谱法监测胆固醇水平的方法和装置
公开(公告)号：US4836207A
公开(公告)日：1989-06-06
申请号：US95052
申请日：1987-09-09
申请人： Sven-Erik Bursell , Juan R. Serur
发明人： Sven-Erik Bursell , Juan R. Serur
IPC分类号： A61B3/12 , A61B3/135
CPC分类号： A61B3/1225 , A61B3/135
摘要： A method to determine the cholesterol level in a patient in a non-invasive manner by delivering a beam of light to a patient's eye. The intensity of light scattered from the aqueous of the eye and the mobility of the protein scatterers in the eye are measured and compared to a control.An apparatus to detect the cholesterol level in a patient in a non-invasive manner which delivers a beam of light to a patient's eye, collects the scattered light from the patient's eye and correlates the scattered light to a cholesterol level measurement.
摘要翻译：一种以非侵入性方式通过将光束传送到患者眼睛来确定患者胆固醇水平的方法。测量从眼睛水分散射的光的强度以及眼睛中的蛋白质散射体的迁移率并与对照进行比较。一种以非侵入性方式检测患者胆固醇水平的装置，其向患者的眼睛传递光束，收集来自患者眼睛的散射光并将散射光与胆固醇水平测量相关联。

4. 发明授权

US07338167B2 Retinal imaging system 失效
标题翻译：视网膜成像系统
公开(公告)号：US07338167B2
公开(公告)日：2008-03-04
申请号：US10732822
申请日：2003-12-10
申请人： Joseph Zelvin , Sven-Erik Bursell
发明人： Joseph Zelvin , Sven-Erik Bursell
IPC分类号： A61B3/14
CPC分类号： A61B3/12 , A61B3/14
摘要： A retinal imaging system includes a light source and optics which receive light from the light source and which transmit the light to produce a beam that is substantially convergent. The beam penetrates a lens of an eye and diverges following penetration of the lens to illuminate an area of a retina of the eye. An imaging device receives a reflection of light from the retina.
摘要翻译：视网膜成像系统包括光源和光学器件，其接收来自光源的光并且透射光以产生基本上会聚的光束。光束穿透眼睛的透镜并且在透镜的穿透之后发散以照亮眼睛的视网膜的区域。成像装置接收来自视网膜的光的反射。

5. 发明申请

US20050134796A1 Retinal imaging system 失效
标题翻译：视网膜成像系统
公开(公告)号：US20050134796A1
公开(公告)日：2005-06-23
申请号：US10732822
申请日：2003-12-10
申请人： Joseph Zelvin , Sven-Erik Bursell
发明人： Joseph Zelvin , Sven-Erik Bursell
IPC分类号： A61B3/12 , A61B3/14
CPC分类号： A61B3/12 , A61B3/14
摘要： A retinal imaging system includes a light source and optics which receive light from the light source and which transmit the light to produce a beam that is substantially convergent. The beam penetrates a lens of an eye and diverges following penetration of the lens to illuminate an area of a retina of the eye. An imaging device receives a reflection of light from the retina.
摘要翻译：视网膜成像系统包括光源和光学器件，其接收来自光源的光并且透射光以产生基本上会聚的光束。光束穿透眼睛的透镜并且在透镜的穿透之后发散以照亮眼睛的视网膜的区域。成像装置接收来自视网膜的光的反射。

6. 发明授权

US5993001A Stereoscopic imaging system for retinal examination with remote examination unit 失效
标题翻译：立体成像系统用于远程检查单元的视网膜检查
公开(公告)号：US5993001A
公开(公告)日：1999-11-30
申请号：US870939
申请日：1997-06-05
申请人： Sven-Erik Bursell , Lloyd M. Aiello , William Kelley Gardner
发明人： Sven-Erik Bursell , Lloyd M. Aiello , William Kelley Gardner
IPC分类号： H04N13/00 , A61B3/10
CPC分类号： G06F19/322 , G06F19/321 , G06F19/3425 , H04N13/0055 , H04N13/0059 , H04N13/0239 , H04N13/0438 , H04N13/0003 , H04N13/0037 , H04N13/0048 , H04N13/0246 , H04N13/0257 , H04N13/0296 , H04N13/0422 , H04N13/0425 , H04N13/0459 , H04N13/0497 , H04N19/597
摘要： An image acquisition unit provides true color high resolution digital images of the retina of the eye to a computer network (14, 16, 18) which interfaces with a central record library and displays the images at a remote work station (20A and 20B) for diagnostic examination. The computer network (14, 16, 18) is also interfaced with a unit for entering medical history information, and the diagnostic data, stereo images and medical records are linked in a relational database allowing all text and image records of the patient to reside on a work station/display (20A and 20B) for review or consultation. A telecommunications link (22) interconnects the computer network and image examination stations with the image acquisition station where the patient is actually examined, so that stereo fundus images may be made available through the computer without degradation for viewing on the examination displays remotely from the room, building, or city where the images are acquired from the patient. By introducing digital true-color normalization at the image acquisition source (34,32), applicant avoids the problem of spurious color artifacts arising when the images are viewed subsequently, or on other monitors.
摘要翻译：图像获取单元将眼睛视网膜的真实颜色高分辨率数字图像提供给与中央记录库接口的计算机网络（14,16,18），并在远程工作站（20A和20B）处显示图像，用于诊断检查。计算机网络（14,16,18）还与用于输入病史信息的单元接口，并且诊断数据，立体图像和医疗记录被链接在关系数据库中，允许患者的所有文本和图像记录驻留在一个工作站/显示器（20A和20B）进行审查或咨询。电信链路（22）将计算机网络和图像检查站与实际检查患者的图像采集站相互连接，使得可以通过计算机使立体眼底图像可用，而不会降低以在远离室内的检查显示器上观看，建筑物或城市，其中从患者获取图像。通过在图像采集源（34,32）处引入数字真彩色标准化，申请人避免了当随后观看图像时或在其他监视器上产生的虚假色彩伪影的问题。

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