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1. 发明授权

US5928164A Apparatus for automated biopsy and collection of soft tissue 失效
标题翻译：用于自动活检和收集软组织的装置
公开(公告)号：US5928164A
公开(公告)日：1999-07-27
申请号：US4737
申请日：1998-01-09
申请人： Fred H. Burbank , Thomas J. Fogarty , Wayne E. Manska , Mark A. Ritchart , Timothy J. Ryan , Elias A. Zerhouni
发明人： Fred H. Burbank , Thomas J. Fogarty , Wayne E. Manska , Mark A. Ritchart , Timothy J. Ryan , Elias A. Zerhouni
IPC分类号： A61B10/02 , A61B10/00 , A61B17/22 , A61B17/30 , A61B17/34 , A61B5/00
CPC分类号： A61B10/0266 , A61B10/0275 , A61B10/0283 , A61B17/221 , A61B2010/0208 , A61B2010/0225 , A61B2017/303
摘要： A method and device for the automated biopsy and collection of soft tissue having a piercing needle with a receiving port to trap tissue prior to cutting. A motor drive directs and positions the tissue receiving port at a lesion site in arbitrary positions about and along the longitudinal axis of the device. A cutter advances into the receiving chamber and severs tissue which has prolapsed into the receiving port. The severed tissue is then removed from the receiving port without removing the piercing needle receiving port from the lesion site, thus allowing for the accurate, rapid removal of an arbitrary number of core samples with only one insertion. A tissue sample cassette provides storage for the samples as well as a means for coding and decoding the location from which the samples were obtained. Together, these features allow for more accurate and complete sampling of large lesions, for the complete removal of small lesions or removal of other tissue for a variety of reasons.
摘要翻译：一种用于自动活检和收集软组织的方法和装置，其具有带有接收端口的穿刺针，以在切割之前捕获组织。马达驱动器将组织接收端口引导并定位在病变位置处，并且沿着装置的纵向轴线的任意位置。切割器进入接收室并切断已经脱垂到接收端口中的组织。然后将切断的组织从接收端口移除而不从病变部位移除穿刺针接收端口，从而允许仅用一个插入准确，快速地去除任意数量的芯样品。组织样品盒为样品提供储存，以及用于编码和解码获得样品的位置的装置。一起，这些特征允许对于大的病变进行更准确和完整的取样，用于由于各种原因完全去除小损伤或去除其他组织。

2. 发明授权

US09216069B2 Methods for defining and marking tissue 有权
公开(公告)号：US09216069B2
公开(公告)日：2015-12-22
申请号：US12625112
申请日：2009-11-24
申请人： Seth A. Foerster , Fred H. Burbank , Mark A. Ritchart , Elias A. Zerbouni
发明人： Seth A. Foerster , Fred H. Burbank , Mark A. Ritchart , Elias A. Zerbouni
IPC分类号： A61B6/00 , A61B19/00 , A61B10/02 , A61B17/00
CPC分类号： A61B19/54 , A61B10/0275 , A61B10/0283 , A61B90/39 , A61B2017/00004 , A61B2090/3908 , A61B2090/3987 , Y10T24/4501
摘要： In order to later identify the location of a biopsy or surgery, various means and methods for permanently and non-surgically marking selected tissue in the human body are used. Later visualization of the markers is readily accomplished using state-of-the-art imaging systems.

3. 发明申请

US20080154151A1 Methods and Devices for Automated Biopsy and Collection of Soft Tissue 失效
标题翻译：自动活组织检查和软组织收集的方法和装置
公开(公告)号：US20080154151A1
公开(公告)日：2008-06-26
申请号：US11931411
申请日：2007-10-31
申请人： Mark A. Ritchart , J. Michael Stuart , Fred H. Burbank , Kenneth M. Galt
发明人： Mark A. Ritchart , J. Michael Stuart , Fred H. Burbank , Kenneth M. Galt
IPC分类号： A61B10/04
CPC分类号： A61B10/0266 , A61B6/12 , A61B8/0841 , A61B10/0275 , A61B10/0283 , A61B17/221 , A61B2010/0208 , A61B2010/0225 , A61B2017/303
摘要： Instruments for performing percutaneous biopsy procedures are disclosed, which have advantageous features for improving functionality and performance over prior art devices. These instruments comprise two types, single-use devices, and multiple-use devices having active tissue capture capability. Improved features include the ability to retrieve and evaluate multiple tissue samples during a single insertion procedure, without physical handling of the samples, as well as constructional features, such as a molded tissue cassette housing, variant vacuum port embodiments suited for different tissue environments, and a method for backflushing the instrument to remove biological debris, among others.
摘要翻译：公开了用于执行经皮活检程序的仪器，其具有改善现有技术装置的功能和性能的有利特征。这些仪器包括两种类型的一次性装置，以及具有活跃组织捕获能力的多用途装置。改进的特征包括在单次插入过程中检索和评估多个组织样本的能力，而不对样品进行物理处理，以及结构特征，例如模制的组织盒壳体，适合于不同组织环境的变体真空端口实施例，以及一种反吹仪器以去除生物碎片的方法等。

4. 发明授权

US6017316A Vacuum control system and method for automated biopsy device 失效
标题翻译：真空控制系统及自动活检装置的方法
公开(公告)号：US6017316A
公开(公告)日：2000-01-25
申请号：US878468
申请日：1997-06-18
申请人： Mark A. Ritchart , Fred H. Burbank , Seth A. Foerster , John L. Wardle
发明人： Mark A. Ritchart , Fred H. Burbank , Seth A. Foerster , John L. Wardle
IPC分类号： A61B10/02 , A61B1/00 , A61B10/00 , A61B17/00 , A61B19/00
CPC分类号： A61B10/0275 , A61B10/0283 , A61B2010/0208 , A61B2017/00017 , A61B2090/0811
摘要： An automatic control system for a vacuum-assisted automatic core biopsy device (10) is provided, wherein the automatic core biopsy device (10) comprises a housing (12), out of which extends a needle assembly (14) including a hollow outer piercing needle (16), an inner cutter (18) having a lumen (20), a probe housing (22), and a tissue receiving notch (24). The automatic control system (92) is computerized to move the hollow outer piercing needle (16) automatically to the target tissue lesion, as was true in the prior art, but also is programmed to automatically control the rotational orientation of the piercing needle (16), and its associated tissue receiving notch (24), as well as the axial positioning and rotation of the cutting cannula (18). Consequently, a clinician user need only mark the desired locations within the target location from which tissue samples are desired and the automatic control system will operate the device to retrieve samples from the marked locations.
摘要翻译：提供了一种用于真空辅助自动核心活检装置（10）的自动控制系统，其中所述自动核心活检装置（10）包括壳体（12），所述壳体（12）从所述壳体（12）延伸出针组件（14），所述针组件包括中空外穿孔针（16），具有内腔（20）的内切割器（18），探针外壳（22）和组织接收凹口（24）。自动控制系统（92）被计算机化以将空心外穿刺针（16）自动移动到目标组织损伤，如现有技术中所述，但也被编程为自动控制穿刺针（16）的旋转取向）和其相关联的组织接收凹口（24）以及切割套管（18）的轴向定位和旋转。因此，临床医师用户仅需要在目标位置标记期望的位置，从该组织样本期望的位置，自动控制系统将操作该装置以从标记的位置检索样本。

5. 发明授权

US07918803B2 Methods and devices for automated biopsy and collection of soft tissue 失效
标题翻译：用于自动活检和收集软组织的方法和装置
公开(公告)号：US07918803B2
公开(公告)日：2011-04-05
申请号：US12535066
申请日：2009-08-04
申请人： Mark A. Ritchart , J. Michael Stuart , Fred H. Burbank , Kenneth M. Galt
发明人： Mark A. Ritchart , J. Michael Stuart , Fred H. Burbank , Kenneth M. Galt
IPC分类号： A61B10/00 , A61B17/32
CPC分类号： A61B10/0266 , A61B6/12 , A61B8/0841 , A61B10/0275 , A61B10/0283 , A61B17/221 , A61B2010/0208 , A61B2010/0225 , A61B2017/303
摘要： A biopsy device and related method are disclosed. The biopsy device disclosed includes a needle having a lateral opening for receiving tissue. The needle may be rotatable with respect to a portion of the biopsy device, such as a housing of the biopsy device, and the needle may be offset from a center of the housing. A hollow cutter is disclosed for cutting tissue received in the lateral opening of the needle.
摘要翻译：公开了活检装置及相关方法。所公开的活检装置包括具有用于接收组织的侧向开口的针。针可以相对于活检装置的一部分（例如活检装置的壳体）旋转，并且针可以偏离壳体的中心。公开了一种用于切割容纳在针的侧向开口中的组织的中空切割器。

6. 发明申请

US20100063415A1 METHODS AND DEVICES FOR AUTOMATED BIOPSY AND COLLECTION OF SOFT TISSUE 失效
标题翻译：用于自动生物学和软组织收集的方法和装置
公开(公告)号：US20100063415A1
公开(公告)日：2010-03-11
申请号：US12535066
申请日：2009-08-04
申请人： Mark A. Ritchart , J. Michael Stuart , Fred H. Burbank , Kareneth M. Gatt
发明人： Mark A. Ritchart , J. Michael Stuart , Fred H. Burbank , Kareneth M. Gatt
IPC分类号： A61B10/02
CPC分类号： A61B10/0266 , A61B6/12 , A61B8/0841 , A61B10/0275 , A61B10/0283 , A61B17/221 , A61B2010/0208 , A61B2010/0225 , A61B2017/303
摘要： A biopsy device and related method are disclosed. The biopsy device disclosed includes a needle having a lateral opening for receiving tissue. The needle may be rotatable with respect to a portion of the biopsy device, such as a housing of the biopsy device, and the needle may be offset from a center of the housing. A hollow cutter is disclosed for cutting tissue received in the lateral opening of the needle.
摘要翻译：公开了活检装置及相关方法。所公开的活检装置包括具有用于接收组织的侧向开口的针。针可以相对于活检装置的一部分（例如活检装置的壳体）旋转，并且针可以偏离壳体的中心。公开了一种用于切割容纳在针的侧向开口中的组织的中空切割器。

7. 发明授权

US5980469A Method and apparatus for automated biopsy and collection of soft tissue 失效
标题翻译：用于软组织自动活检和收集的方法和装置
公开(公告)号：US5980469A
公开(公告)日：1999-11-09
申请号：US4782
申请日：1998-01-09
申请人： Fred H. Burbank , Thomas J. Fogarty , Wayne E. Manska , Mark A. Ritchart , Timothy J. Ryan , Elias A. Zerhouni
发明人： Fred H. Burbank , Thomas J. Fogarty , Wayne E. Manska , Mark A. Ritchart , Timothy J. Ryan , Elias A. Zerhouni
IPC分类号： A61B10/02 , A61B10/00 , A61B17/22 , A61B17/30 , A61B17/34
CPC分类号： A61B10/0266 , A61B10/0275 , A61B10/0283 , A61B17/221 , A61B2010/0208 , A61B2010/0225 , A61B2017/303
摘要： A method and device for the automated biopsy and collection of soft tissue having a piercing needle with a receiving port to trap tissue prior to cutting. A motor drive directs and positions the tissue receiving port at a lesion site in arbitrary positions about and along the longitudinal axis of the device. A cutter advances into the receiving chamber and severs tissue which has prolapsed into the receiving port. The severed tissue is then removed from the receiving port without removing the piercing needle receiving port from the lesion site, thus allowing for the accurate, rapid removal of an arbitrary number of core samples with only one insertion. A tissue sample cassette provides storage for the samples as well as a means for coding and decoding the location from which the samples were obtained. Together, these features allow for more accurate and complete sampling of large lesions, for the complete removal of small lesions or removal of other tissue for a variety of reasons.
摘要翻译：一种用于自动活检和收集软组织的方法和装置，其具有带有接收端口的穿刺针，以在切割之前捕获组织。马达驱动器将组织接收端口引导并定位在病变位置处，并且沿着装置的纵向轴线的任意位置。切割器进入接收室并切断已经脱垂到接收端口中的组织。然后将切断的组织从接收端口移除而不从病变部位移除穿刺针接收端口，从而允许仅用一个插入准确，快速地去除任意数量的芯样品。组织样品盒为样品提供储存，以及用于编码和解码获得样品的位置的装置。一起，这些特征允许对于大的病变进行更准确和完整的取样，用于由于各种原因完全去除小损伤或去除其他组织。

8. 发明授权

US5810806A Methods and devices for collection of soft tissue 失效
标题翻译：用于收集软组织的方法和装置
公开(公告)号：US5810806A
公开(公告)日：1998-09-22
申请号：US705622
申请日：1996-08-29
申请人： Mark A. Ritchart , Minh Tran , Mark Cole , Fred H. Burbank
发明人： Mark A. Ritchart , Minh Tran , Mark Cole , Fred H. Burbank
IPC分类号： A61B10/02 , A61B10/00 , A61B17/00 , A61B17/32 , A61B18/14 , A61B19/00 , A61B17/39
CPC分类号： A61B10/0266 , A61B18/1482 , A61B10/02 , A61B2017/0046 , A61B2017/00796 , A61B2017/32004 , A61B2018/00208 , A61B2018/1407 , A61B2018/1861 , A61B2090/062 , A61B2090/378 , A61B2090/3908
摘要： This invention provides an inventive tissue sampling probe which offers many advantages over probes available in the prior art. Unexpectedly superior results are obtained in connection with the retrieval of intact tissue specimens, because of a unique combination of cutting features, including, for example, the employment of an electrosurgical cutting element and a vacuum assist in one preferred embodiment. A particularly important feature of the invention is the ability to manipulate the electrosurgical cutting element to cleanly sever the distal end of the tissue specimen. In certain embodiments, this is accomplished without any cutting impact on surrounding tissue. The versatility of the invention permits its use in many applications, including, for example, breast biopsies, laparoscopic surgery, and lymphadenectomy procedures.
摘要翻译：本发明提供了一种创新的组织取样探针，其提供了优于现有技术中可用的探针的许多优点。由于在一个优选实施例中包括例如使用电外科切割元件和真空辅助的切割特征的独特组合，可以获得与完整组织标本的检索有关的意想不到的优异结果。本发明的一个特别重要的特征是能够操纵电外科切割元件来清洁地切断组织标本的远端。在某些实施方案中，这是在对周围组织没有任何切割冲击的情况下实现的。本发明的多功能性允许其在许多应用中使用，包括例如乳房活组织检查，腹腔镜手术和淋巴结清扫手术。

9. 发明授权

US5775333A Apparatus for automated biopsy and collection of soft tissue 失效
公开(公告)号：US5775333A
公开(公告)日：1998-07-07
申请号：US645225
申请日：1996-05-13
申请人： Fred H. Burbank , Thomas J. Fogarty , Wayne E. Manska , Mark A. Ritchart , Timothy J. Ryan , Elias A. Zerhouni
发明人： Fred H. Burbank , Thomas J. Fogarty , Wayne E. Manska , Mark A. Ritchart , Timothy J. Ryan , Elias A. Zerhouni
IPC分类号： A61B10/02 , A61B10/00 , A61B17/22 , A61B17/30 , A61B17/34
CPC分类号： A61B10/0266 , A61B10/0275 , A61B10/0283 , A61B17/221 , A61B2010/0208 , A61B2010/0225 , A61B2017/303
摘要： A method and device for the automated biopsy and collection of soft tissue having a piercing needle with a receiving port to trap tissue prior to cutting. A motor drive directs and positions the tissue receiving port at a lesion site in arbitrary positions about and along the longitudinal axis of the device. A cutter advances into the receiving chamber and severs tissue which has prolapsed into the receiving port. The severed tissue is then removed from the receiving port without removing the piercing needle receiving port from the lesion site, thus allowing for the accurate, rapid removal of an arbitrary number of core samples with only one insertion. A tissue sample cassette provides storage for the samples as well as a means for coding and decoding the location from which the samples were obtained. Together, these features allow for more accurate and complete sampling of large lesions, for the complete removal of small lesions or removal of other tissue for a variety of reasons.

10. 发明授权

US5769086A Control system and method for automated biopsy device 失效
标题翻译：自动活检装置的控制系统和方法
公开(公告)号：US5769086A
公开(公告)日：1998-06-23
申请号：US568143
申请日：1995-12-06
申请人： Mark A. Ritchart , Fred H. Burbank
发明人： Mark A. Ritchart , Fred H. Burbank
IPC分类号： A61B10/02 , A61B10/00 , A61B19/00
CPC分类号： A61B10/0275 , A61B10/0283 , A61B2010/0208 , A61B2090/378 , A61B34/10 , A61B34/25 , A61B34/70
摘要： An automatic control system for a vacuum-assisted automatic core biopsy device (10) is provided, wherein the automatic core biopsy device (10) comprises a housing (12), out of which extends a needle assembly (14) including a hollow outer piercing needle (16), an inner cutter (18) having a lumen (20), a probe housing (22), and a tissue receiving notch (24). The automatic control system (92) is computerized to move the hollow outer piercing needle (16) automatically to the target tissue lesion, as was true in the prior art, but also is programmed to automatically control the rotational orientation of the piercing needle (16), and its associated tissue receiving notch (24), as well as the axial positioning and rotation of the cutting cannula (18). Consequently, a clinician user need only mark the desired locations within the target location from which tissue samples are desired and the automatic control system will operate the device to retrieve samples from the marked locations.
摘要翻译：提供了一种用于真空辅助自动核心活检装置（10）的自动控制系统，其中所述自动核心活检装置（10）包括壳体（12），所述壳体（12）从所述壳体（12）延伸出针组件（14），所述针组件包括中空外穿孔针（16），具有内腔（20）的内切割器（18），探针外壳（22）和组织接收凹口（24）。自动控制系统（92）被计算机化以将空心外穿刺针（16）自动移动到目标组织损伤，如现有技术中所述，但也被编程为自动控制穿刺针（16）的旋转取向）和其相关联的组织接收凹口（24）以及切割套管（18）的轴向定位和旋转。因此，临床医师用户仅需要在目标位置标记期望的位置，从该组织样本期望的位置，自动控制系统将操作该装置以从标记的位置检索样本。

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