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1. 发明授权

US06649628B1 N-[2-hydroxy-3-(1-piperidinyl)propoxy]pyridine-1-oxide-3-carboximidoyl chloride and its use in the treatment of insulin resistance 有权
标题翻译： N- [2-羟基-3-（1-哌啶基）丙氧基]吡啶-1-氧化物-3-甲酰亚胺酰氯及其在治疗胰岛素抵抗中的应用
公开(公告)号：US06649628B1
公开(公告)日：2003-11-18
申请号：US09913263
申请日：2001-12-18
申请人： Maria Kürthy , Katalin Bíró , Károly Nagy , László Ürögdi , Zita Csákai , Jenö Szilbereky , Tamás Mogyorósi , Magdolna Török , András Komáromi , Ede Márványos , Mihály Barabás , Mihályné Kardos , Zoltán Nagy , László Korányi , Melinda Nagy
发明人： Maria Kürthy , Katalin Bíró , Károly Nagy , László Ürögdi , Zita Csákai , Jenö Szilbereky , Tamás Mogyorósi , Magdolna Török , András Komáromi , Ede Márványos , Mihály Barabás , Mihályné Kardos , Zoltán Nagy , László Korányi , Melinda Nagy
IPC分类号： A61K31445
CPC分类号： C07D213/89
摘要： N-[2-hydroxy-3-(1-piperidinyl)-propoxy]-pyridine-1-oxide-3-carboximidoyl chloride, its stereoisomers, and the addition salts thereof, pharmaceutical compositions containing the same, methods of treating pathological insulin resistance, methods of treating pathological insulin resistance and pathological conditions associated therewith, and methods of treating pathological insulin resistance by simultaneously treating diabetes-induced chronic complications, especially retinopathy, neuropathy and nephropathy, and/or by simultaneously increasing pathologically decreased peripheral neuroregeneration caused by diabetes.
摘要翻译： N- [2-羟基-3-（1-哌啶基） - 丙氧基] - 吡啶-1-氧化物-3-甲酰亚胺酰氯，其立体异构体及其加成盐，含有它们的药物组合物，治疗病理性胰岛素抵抗的方法治疗病理性胰岛素抵抗的方法以及通过同时治疗糖尿病诱发的慢性并发症，尤其是视网膜病变，神经病变和肾病，和/或通过同时增加由糖尿病引起的周围神经再生的病理学降低来治疗病理性胰岛素抵抗的方法。

2. 发明申请

US20130215245A1 METHOD AND APPARATUS FOR HAND DISINFECTION QUALITY CONTROL 有权
标题翻译：手动消毒质量控制的方法和装置
公开(公告)号：US20130215245A1
公开(公告)日：2013-08-22
申请号：US13824240
申请日：2011-09-23
申请人： Tamas Haidegger , Melinda Nagy , Akos Lehotsky , Laszlo Szilanyi
发明人： Tamas Haidegger , Melinda Nagy , Akos Lehotsky , Laszlo Szilanyi
IPC分类号： G08B21/24
CPC分类号： G08B21/245 , G08B21/24
摘要： The invention is based on a method for hand disinfection quality control comprising the steps of providing a hand disinfection medium comprising a light reflecting particles responsive to light mostly outside the visible spectral range of light, applying the hand disinfection medium comprising the light reflecting particles in a prescribed manner for a prescribed time, illuminating the hands disinfected this way with a light source providing light in a spectral range for activating the reflecting particles. The method according to the invention further comprises the steps of providing digital images of the hands from both sides, and evaluating the images by a computer program in order to determine the cleanness of the hands. The invention also relates to an apparatus for implementing the method and assessing hand disinfection quality. The invention uses an apparatus that comprises a rigid case with side walls enclosing a light source for providing light of a predetermined spectral range mostly outside the visible range. The case is further provided with an opening on the front wall for introducing the hands to be exposed to the light of the light source. An imaging device is also attached to the case for taking images of the illuminated hands.
摘要翻译：本发明是基于一种手消毒质量控制方法，包括以下步骤：提供一种手消毒介质，该手消毒介质包含响应多数在光可见光范围之外的光的光反射颗粒，将含有光反射颗粒的手消毒介质以规定的方式规定时间，照亮用这种方式消毒的手，用光源提供用于激活反射粒子的光谱范围内的光。根据本发明的方法还包括以下步骤：从两侧提供手的数字图像，以及通过计算机程序评估图像，以便确定手的清洁度。本发明还涉及一种用于实施该方法并评估手消毒质量的装置。本发明使用的装置包括刚性壳体，侧壁包围光源，用于提供主要在可见光范围外的预定光谱范围的光。该壳体还在前壁上设置有用于引入要暴露于光源的光的手的开口。成像装置也附接到用于拍摄照明手的图像的壳体。

3. 发明授权

US09424735B2 Method and apparatus for hand disinfection quality control 有权
标题翻译：手消毒质量控制方法和装置
公开(公告)号：US09424735B2
公开(公告)日：2016-08-23
申请号：US13824240
申请日：2011-09-23
申请人： Tamas Haidegger , Melinda Nagy , Akos Lehotsky , Laszlo Szilanyi
发明人： Tamas Haidegger , Melinda Nagy , Akos Lehotsky , Laszlo Szilanyi
IPC分类号： G08B21/24
CPC分类号： G08B21/245 , G08B21/24
摘要： Method and apparatus for hand disinfection quality control comprising the steps of providing hand disinfection medium comprising light reflecting particles responsive to light mostly outside the visible spectral range of light, applying the hand disinfection medium comprising the light reflecting particles in a prescribed manner for a prescribed time, illuminating the disinfected hands with a light source providing light in a spectral range for activating the reflecting particles. The method further comprises providing digital images of the hands from both sides, determining the concentration of reflecting particles, comparing determined concentration values with a predetermined threshold value corresponding to acceptable hand cleanness, and determining whether the quality of disinfection is acceptable or not according to the result of comparison. In the method according to the invention for each person individual threshold value is stored, and the concentration value determined during measuring is compared with the individual threshold value.
摘要翻译：用于手消毒质量控制的方法和装置包括以下步骤：提供手消毒介质，所述手消毒介质包括响应于主要在可见光光谱范围外的光的光反射颗粒，以规定的方式施加包含光反射颗粒的手消毒介质达规定时间用光源照射消毒的手，提供用于激活反射颗粒的光谱范围内的光。该方法还包括从两侧提供手的数字图像，确定反射粒子的浓度，将确定的浓度值与对应于可接受的手部清洁度的预定阈值进行比较，以及根据所述方法确定消毒质量是否可接受比较结果。在根据本发明的每个人的方法中存储个体阈值，并将测量期间确定的浓度值与个体阈值进行比较。

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