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1. 发明申请

US20080177127A1 Asymmetric Radiation Dosing Devices and Methods for Brachytherapy 审中-公开
标题翻译：不对称放射剂量及近距离放射治疗方法
公开(公告)号：US20080177127A1
公开(公告)日：2008-07-24
申请号：US11959252
申请日：2007-12-18
申请人： Donna Allan , Greg Amante , Risa Anav , Maria Benson , Michael Crocker , Gregory K. Edmundson , Friedrick Ho , Robert Kotmel , Glenn Magnuson , Gregory T. Martin , Walter Ocampo , Mukund Patel , F. Mark Payne , Russel Sampson , Jessica Schenck , James Stubbs , Moshe Zilversmit
发明人： Donna Allan , Greg Amante , Risa Anav , Maria Benson , Michael Crocker , Gregory K. Edmundson , Friedrick Ho , Robert Kotmel , Glenn Magnuson , Gregory T. Martin , Walter Ocampo , Mukund Patel , F. Mark Payne , Russel Sampson , Jessica Schenck , James Stubbs , Moshe Zilversmit
IPC分类号： A61M36/04
CPC分类号： A61N5/1015 , A61M25/1002 , A61M25/1011 , A61M2025/1013 , A61N2005/1005
摘要： A brachytherapy treatment device includes at least one tubular insertion member, an expandable member, and means for deflecting the at least one tubular insertion member. The tubular insertion member has a longitudinal axis and proximal and distal ends. The expandable member is disposed on and surrounding the distal end of the tubular insertion member. The distal end of the at least one deflected tubular insertion member within the first expandable member is offset from the longitudinal axis when deflected. The at least one deflected tubular insertion member is configured to receive a radiation source to position a radiation source offset with regard to the longitudinal axis to form an asymmetric radiation dosing profile. Additional brachytherapy treatment devices and methods for forming an asymmetric radiation dosing profile are disclosed.
摘要翻译：近程放射疗法治疗装置包括至少一个管状插入构件，可膨胀构件和用于偏转至少一个管状插入构件的装置。管状插入构件具有纵向轴线和近端和远端。可扩张构件设置在管状插入构件的远端上且围绕管状插入构件的远端。当第一可膨胀构件中的至少一个偏转的管状插入构件的远端偏转时偏离纵向轴线。所述至少一个偏转的管状插入构件被配置为接收辐射源以相对于纵向轴线偏置辐射源以形成不对称的辐射剂量分布。公开了用于形成不对称辐射剂量分布的附加的近距离放射治疗装置和方法。

2. 发明申请

US20100217064A1 PASSIVE VENT FOR BRACHYTHERAPY BALLOON CATHETERS 有权
标题翻译：被动式通风器用于缓冲气囊导管
公开(公告)号：US20100217064A1
公开(公告)日：2010-08-26
申请号：US12389577
申请日：2009-02-20
申请人： Maria Benson , Donna Allan , Walter Ocampo
发明人： Maria Benson , Donna Allan , Walter Ocampo
IPC分类号： A61M36/12 , A61L2/00
CPC分类号： A61L2/20 , A61L2/07 , A61L2/08 , A61L2/081 , A61L2/082 , A61L2/087 , A61L2/10 , A61L2/14 , A61L2/202 , A61L2/206 , A61L2/208 , A61L2202/24 , A61M39/22 , A61N5/1001
摘要： Embodiments of passive vent valve devices are disclosed. One of the novel aspects of the invention is its ability to transform from a packaging configuration to a use configuration. The packaging configuration allows sterilization gases to penetrate into the device through standard valve openings as well as through vented mesh openings. Passage of gas into the device, in turn, provides a means of sterilizing all surface areas in the device. Alternatively, when the valve is placed in a use configuration, the passage of gas through the vented mesh is inhibited providing a sealed environment that functions as a valve. The invention is useful in manufacturing sterile medical devices by allowing all surfaces to communicate with the sterilizing agent when the valve is in a packaging configuration or when it is in a use configuration.
摘要翻译：公开了被动式排气阀装置的实施例。本发明的新颖方面之一是其从包装配置转变为使用配置的能力。包装配置允许消毒气体通过标准阀门开口以及通过排气网孔渗透到设备中。气体通入装置又提供了对装置中的所有表面区域进行灭菌的手段。或者，当阀被放置在使用构型中时，气体通过排气网的通过被抑制，提供用作阀的密封环境。本发明在制造无菌医疗装置时可用于当阀处于包装配置中时或当其处于使用配置时允许所有表面与灭菌剂连通。

3. 发明申请

US20090143634A1 Brachytherapy Balloon Features 审中-公开
标题翻译：近距离放射治疗气球特征
公开(公告)号：US20090143634A1
公开(公告)日：2009-06-04
申请号：US11949882
申请日：2007-12-04
申请人： Maria Benson , Donna Allan , Walter Ocampo
发明人： Maria Benson , Donna Allan , Walter Ocampo
IPC分类号： A61N5/00
CPC分类号： A61N5/1015
摘要： A brachytherapy treatment device includes a tubular insertion member and an expandable chamber. The tubular insertion member has a proximal end and a distal end and an expandable chamber disposed on the distal end of the tubular insertion member. The expandable chamber defines an enclosed space and has inner and outer surfaces defining a wall, wherein the wall has at least first and second wall thicknesses. The expandable chamber may comprise a balloon. A main body portion of the balloon has the first wall thickness and ribs have the second wall thickness. The ribs may be disposed to be approximately parallel or perpendicular to the tubular insertion member around the circumference of the balloon. The ribs or other thickened areas provide improved symmetry, stability, and strength to an inflated balloon. Methods of forming a symmetrical radiation dosing profile are also disclosed herein.
摘要翻译：近程放射治疗装置包括管状插入构件和可扩张腔。管状插入构件具有近端和远端以及设置在管状插入构件的远端上的可扩张腔。可膨胀室限定封闭空间，并且具有限定壁的内表面和外表面，其中壁具有至少第一和第二壁厚度。可膨胀室可以包括气球。球囊的主体部分具有第一壁厚，肋具有第二壁厚。肋可以设置成围绕球囊的圆周大致平行或垂直于管状插入构件。肋骨或其他加厚区域对充气球囊提供改善的对称性，稳定性和强度。形成对称辐射剂量分布的方法也在本文中公开。

4. 发明授权

US08403822B2 Passive vent for brachytherapy balloon catheters 有权
标题翻译：近距离放射治疗气球导管的被动通气
公开(公告)号：US08403822B2
公开(公告)日：2013-03-26
申请号：US12389577
申请日：2009-02-20
申请人： Maria Benson , Donna Allan , Walter Ocampo
发明人： Maria Benson , Donna Allan , Walter Ocampo
IPC分类号： A61N5/00
CPC分类号： A61L2/20 , A61L2/07 , A61L2/08 , A61L2/081 , A61L2/082 , A61L2/087 , A61L2/10 , A61L2/14 , A61L2/202 , A61L2/206 , A61L2/208 , A61L2202/24 , A61M39/22 , A61N5/1001
摘要： Embodiments of passive vent valve devices are disclosed. One of the novel aspects of the invention is its ability to transform from a packaging configuration to a use configuration. The packaging configuration allows sterilization gases to penetrate into the device through standard valve openings as well as through vented mesh openings. Passage of gas into the device, in turn, provides a means of sterilizing all surface areas in the device. Alternatively, when the valve is placed in a use configuration, the passage of gas through the vented mesh is inhibited providing a sealed environment that functions as a valve. The invention is useful in manufacturing sterile medical devices by allowing all surfaces to communicate with the sterilizing agent when the valve is in a packaging configuration or when it is in a use configuration.
摘要翻译：公开了被动式排气阀装置的实施例。本发明的新颖方面之一是其从包装配置转变为使用配置的能力。包装配置允许消毒气体通过标准阀门开口以及通过排气网孔渗透到设备中。气体通入装置又提供了对装置中的所有表面区域进行灭菌的手段。或者，当阀被放置在使用构型中时，气体通过排气网的通过被抑制，提供用作阀的密封环境。本发明在制造无菌医疗装置时可用于当阀处于包装配置中时或当其处于使用配置时允许所有表面与灭菌剂连通。

5. 发明申请

US20090156880A1 Selectable Multi-Lumen Brachytherapy Devices and Methods 有权
公开(公告)号：US20090156880A1
公开(公告)日：2009-06-18
申请号：US11959227
申请日：2007-12-18
申请人： Donna Allan , Greg Amante
发明人： Donna Allan , Greg Amante
IPC分类号： A61M36/04
CPC分类号： A61N5/1015 , A61N2005/1005 , A61N2005/1018
摘要： A brachytherapy treatment device includes at least one tubular insertion member and an expandable member. The tubular insertion member has proximal and distal ends and at least one radiation source lumen disposed along its length and branching at the distal end to provide a plurality of selectable radiation source lumens each configured to receive a radiation source. The expandable member is disposed on and surrounding the distal end of the tubular insertion member. In another embodiment, a brachytherapy treatment device may also include a plurality of selectable radiation source lumens forming an arcuate shape with respect to the longitudinal axis. Additional brachytherapy treatment devices and methods for performing brachytherapy and for forming an asymmetric radiation dosing profile are also disclosed.

6. 发明申请

US20090156879A1 Selectable Multi-Lumen Brachytherapy Devices and Methods 审中-公开
标题翻译：可选择多流明近距离放射治疗装置及方法
公开(公告)号：US20090156879A1
公开(公告)日：2009-06-18
申请号：US11959211
申请日：2007-12-18
申请人： Donna Allan , Greg Amante
发明人： Donna Allan , Greg Amante
IPC分类号： A61M36/04
CPC分类号： A61N5/1015 , A61N2005/1005
摘要： A brachytherapy treatment device includes at least one tubular insertion member and an expandable member. The tubular insertion member has proximal and distal ends and at least one radiation source lumen disposed along its length and branching at the distal end to provide a plurality of selectable radiation source lumens each configured to receive a radiation source. The expandable member is disposed on and surrounding the distal end of the tubular insertion member. In another embodiment, a brachytherapy treatment device may also include a plurality of selectable radiation source lumens forming an arcuate shape with respect to the longitudinal axis. Additional brachytherapy treatment devices and methods for performing brachytherapy and for forming an asymmetric radiation dosing profile are also disclosed.
摘要翻译：近程放射治疗装置包括至少一个管状插入构件和可扩张构件。管状插入构件具有近端和远端以及至少一个辐射源腔，沿着其长度设置并在远端分支，以提供多个可选择的辐射源腔，每个被配置为接收辐射源。可扩张构件设置在管状插入构件的远端上且围绕管状插入构件的远端。在另一个实施例中，近距离放射疗法治疗装置还可以包括相对于纵向轴线形成弓形形状的多个可选择的辐射源腔。还公开了用于进行近距离放射治疗和形成不对称辐射剂量分布的附加近距离放射线治疗装置和方法。

7. 发明授权

US08328711B2 Selectable multi-lumen brachytherapy devices and methods 有权
标题翻译：可选多腔近距离放射治疗装置及方法
公开(公告)号：US08328711B2
公开(公告)日：2012-12-11
申请号：US11959227
申请日：2007-12-18
申请人： Donna Allan , Greg Amante
发明人： Donna Allan , Greg Amante
IPC分类号： A61N5/00
CPC分类号： A61N5/1015 , A61N2005/1005 , A61N2005/1018
摘要： A brachytherapy treatment device includes at least one tubular insertion member and an expandable member. The tubular insertion member has proximal and distal ends and at least one radiation source lumen disposed along its length and branching at the distal end to provide a plurality of selectable radiation source lumens each configured to receive a radiation source. The expandable member is disposed on and surrounding the distal end of the tubular insertion member. In another embodiment, a brachytherapy treatment device may also include a plurality of selectable radiation source lumens forming an arcuate shape with respect to the longitudinal axis. Additional brachytherapy treatment devices and methods for performing brachytherapy and for forming an asymmetric radiation dosing profile are also disclosed.
摘要翻译：近程放射治疗装置包括至少一个管状插入构件和可扩张构件。管状插入构件具有近端和远端以及至少一个辐射源腔，沿着其长度设置并在远端分支，以提供多个可选择的辐射源腔，每个被配置为接收辐射源。可扩张构件设置在管状插入构件的远端上且围绕管状插入构件的远端。在另一个实施例中，近距离放射疗法治疗装置还可以包括相对于纵向轴线形成弓形形状的多个可选择的辐射源腔。还公开了用于进行近距离放射治疗和形成不对称辐射剂量分布的附加近距离放射线治疗装置和方法。

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