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1. 发明申请

US20180021463A1 METHODS AND COMPOSITIONS FOR ANTIMICROBIAL TREATMENT 审中-公开
公开(公告)号：US20180021463A1
公开(公告)日：2018-01-25
申请号：US15549974
申请日：2016-02-09
申请人： Marek A. Osinski , Hugh D.C. Smyth , Leisha Marie Armijo , Hennaka Mudiyanselage Herath Nihal Bandara
发明人： Marek A. Osinski , Hugh D.C. Smyth , Leisha Marie Armijo , Hennaka Mudiyanselage Herath Nihal Bandara
IPC分类号： A61L2/02 , A61K41/00 , A61L29/10 , A61K33/26 , A61L2/238 , A61L31/08
CPC分类号： A61L2/02 , A01N25/26 , A61K33/26 , A61K41/00 , A61L2/238 , A61L29/106 , A61L31/088 , A01N59/16
摘要： Various embodiments disclosed relate to methods and compositions for antimicrobial treatment. In various embodiments, the present invention provides a method of antimicrobial treatment. The method includes at least one of exposing at least one microbe to a magnetic field, and contacting the at least one microbe with at least one nanoparticle including iron.

2. 发明授权

US11135325B2 Methods and compositions for antimicrobial treatment 有权
公开(公告)号：US11135325B2
公开(公告)日：2021-10-05
申请号：US15549974
申请日：2016-02-09
申请人： Marek A. Osinski , Hugh D. C. Smyth , Leisha Marie Armijo , Hennaka Mudiyanselage Herath Nihal Bandara
发明人： Marek A. Osinski , Hugh D. C. Smyth , Leisha Marie Armijo , Hennaka Mudiyanselage Herath Nihal Bandara
IPC分类号： A61L2/02 , A01N25/26 , A61K33/26 , A61K41/00 , A61L2/238 , A61L29/10 , A61L31/08
摘要： Various embodiments disclosed relate to methods and compositions for antimicrobial treatment. In various embodiments, the present invention provides a method of antimicrobial treatment. The method includes at least one of exposing at least one microbe to a magnetic field, and contacting the at least one microbe with at least one nanoparticle including iron.

3. 发明申请

US20210393815A1 METHODS AND COMPOSITIONS FOR ANTIMICROBIAL TREATMENT 有权
公开(公告)号：US20210393815A1
公开(公告)日：2021-12-23
申请号：US17466189
申请日：2021-09-03
申请人： Marek A. Osinski , Hugh D. C. Smyth , Leisha Marie Armijo , Hennaka Mudiyanselage Herath Nihal Bandara
发明人： Marek A. Osinski , Hugh D. C. Smyth , Leisha Marie Armijo , Hennaka Mudiyanselage Herath Nihal Bandara
IPC分类号： A61L2/02 , A01N25/26 , A61K33/26 , A61K41/00 , A61L2/238 , A61L29/10 , A61L31/08
摘要： Various embodiments disclosed relate to methods and compositions for antimicrobial treatment. In various embodiments, the present invention provides a method of antimicrobial treatment. The method includes at least one of exposing at least one microbe to a magnetic field, and contacting the at least one microbe with at least one nanoparticle including iron.

4. 发明授权

US08431041B2 Halide-based scintillator nanomaterial 有权
标题翻译：卤化物闪烁体纳米材料
公开(公告)号：US08431041B2
公开(公告)日：2013-04-30
申请号：US12386503
申请日：2009-04-17
申请人： Marek A. Osinski , Nathan J. Withers , Brian A. Akins , Gennady A. Smolyakov , Krishnaprasad Sankar
发明人： Marek A. Osinski , Nathan J. Withers , Brian A. Akins , Gennady A. Smolyakov , Krishnaprasad Sankar
IPC分类号： C09K11/08 , C09K11/61
CPC分类号： C09K11/7773 , C09K11/664 , C09K11/7772 , G01T1/20 , G01T1/202 , Y10T428/256 , Y10T428/2982
摘要： Scintillator material comprising nanoparticles (nanocrystals) comprising lead (Pb), iodine (I), and optionally one or both of oxygen (O) and hydrogen (H) wherein the nanoparticles exhibit room-temperature scintillation under gamma irradiation. The scintillator nanoparticles can comprise Pb3O2I2. The scintillator nanoparticles can comprise PbIOH in generally equiatomic proportions or non-equiatomic variants thereof that exhibit scintillation under gamma irradiation. The scintillator nanoparticles have a particle dimension in the range of about 5 to about 100 nm. Microparticles (microcrystals) also are provided comprising lead (Pb), iodine (I), and optionally one or both of oxygen (O) and hydrogen (H) grown in a nanoparticle colloidal solution over time to a particle dimension greater than 0.1 μm, such as about 2 microns. A heterogeneous scintillator material is provided comprising core/shell nanoparticles having a highly hygroscopic or deliquescent halide-based core activated with trivalent Ln3+ or divalent Ln2+ lanthanide ions (Ln=La, Ce, Pr, Nd, Pm, Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm, Yb, Lu) and a stable non-hygroscopic shell thereon. The heterogeneous nanoparticles can comprise highly hygroscopic lanthanide halide (LaBr3, LuI3) cores protected with stable non-hygroscopic LaF3 shells. The heterogeneous nanoparticles can comprise deliquescent alkaline earth halide (SrI2, BaI2) cores protected with stable non-hygroscopic (SrF2, BaF2) shells.
摘要翻译：包含包含铅（Pb），碘（I）和任选的氧（O）和氢（H）中的一种或两者的纳米颗粒（纳米晶体）的闪烁体材料，其中纳米颗粒在γ照射下呈现室温闪烁。闪烁体纳米颗粒可以包含Pb 3 O 2 I 2。闪烁体纳米颗粒可以包含通常等原子比例的PbIOH或在γ照射下显示闪烁的非等摩尔变体。闪烁体纳米颗粒具有在约5至约100nm范围内的粒子尺寸。还提供包含铅（Pb），碘（I）以及任选的在纳米颗粒胶体溶液中生长的氧（O）和氢（H）中的一种或两种随时间变化至大于0.1μm的颗粒尺寸的微颗粒（微晶）例如约2微米。提供了一种异质闪烁体材料，其包括具有由三价Ln3 +或二价Ln2 +镧系元素离子（Ln = La，Ce，Pr，Nd，Pm，Sm，Eu，Gd，Tb）活化的高吸湿性或潮解性卤化物基核心的核/壳纳米颗粒，Dy，Ho，Er，Tm，Yb，Lu）和稳定的非吸湿性外壳。非均相纳米颗粒可以包含用稳定的非吸湿性LaF 3壳保护的高吸湿性镧系元素卤化物（LaBr 3，LuI 3）。非均相纳米颗粒可以包含用稳定的非吸湿性（SrF 2，BaF 2）壳保护的潮解性碱土卤化物（SrI 2，BaI 2）。

5. 发明授权

US06937342B2 Monolithically integrated semiconductor unidirectional ring laser rotation sensor/gyroscope 有权
标题翻译：单片半导体单向环形激光旋转传感器/陀螺仪
公开(公告)号：US06937342B2
公开(公告)日：2005-08-30
申请号：US10195141
申请日：2002-07-11
申请人： Marek A. Osinski , Edward W. Taylor , Petr G. Eliseev
发明人： Marek A. Osinski , Edward W. Taylor , Petr G. Eliseev
IPC分类号： G01C19/72 , G01C19/66
CPC分类号： G01C19/72
摘要： A monolithically integrated semiconductor laser rotation sensor/gyroscope that includes at least two isolated, nonsynchronized semiconductor lasers; at least one being unidirectional and at least a further one being either a straight-line laser or a second unidirectional ring laser configured to propagate lasing light waves in the direction opposite to the first unidirectional ring laser; semiconductor directional waveguide couplers; a semiconductor Y-junction mixing region; and a semiconductor photodetector. Evanescently outcoupled signals are routed to a photodetector for detection of the Sagnac shifted frequencies to discern a beat frequency resulting from rotation of the chip structure. The straight-line semiconductor laser serves as frequency reference insensitive to rotation. Directing, filtering, and radiating unwanted reflections or backscattered light to highly absorbing regions is carried out with waveguide coupler designs and nonreciprocal couplers and filters.
摘要翻译：包括至少两个隔离的非同步半导体激光器的单片集成半导体激光旋转传感器/陀螺仪; 至少一个是单向的，并且至少另外一个是被配置成沿与第一单向环形激光器相反的方向传播激光光的直线激光器或第二单向环形激光器; 半导体定向波导耦合器; 半导体Y结混合区域; 和半导体光电检测器。衰减的输出耦合信号被路由到光电检测器，用于检测Sagnac移位的频率以识别由芯片结构的旋转产生的拍频。直线半导体激光器作为对旋转不敏感的频率基准。使用波导耦合器设计和非互易耦合器和滤波器进行引导，滤波和辐射不需要的反射或反向散射光到高吸收区域。

6. 发明授权

US09644141B2 Halide-based scintillator nanomaterial 有权
公开(公告)号：US09644141B2
公开(公告)日：2017-05-09
申请号：US13986039
申请日：2013-03-26
申请人： Marek A. Osinski , Nathan J. Withers , Brian A. Akins , Gennady A. Smolyakov , Krishnaprasad Sankar
发明人： Marek A. Osinski , Nathan J. Withers , Brian A. Akins , Gennady A. Smolyakov , Krishnaprasad Sankar
IPC分类号： C09K11/77 , C09K11/66 , G01T1/202 , G01T1/20
CPC分类号： C09K11/7773 , C09K11/664 , C09K11/7772 , G01T1/20 , G01T1/202 , Y10T428/256 , Y10T428/2982
摘要： A heterogeneous scintillator material is provided comprising core/shell nanoparticles having a highly hygroscopic or deliquescent halide-based core activated with trivalent Ln3+ or divalent Ln2+ lanthanide ions (Ln=La, Ce, Pr, Nd, Pm, Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm, Yb, Lu) and a stable non-hygroscopic shell thereon. The heterogeneous nanoparticles can comprise highly hygroscopic lanthanide halide (LaBr3, LuI3) cores protected with stable non-hygroscopic LaF3 shells. The heterogeneous nanoparticles can comprise deliquescent alkaline earth halide (SrI2, BaI2) cores protected with stable non-hygroscopic (SrF2, BaF2) shells.

7. 发明申请

US20120145532A1 Efficient hydrogen production by photocatalytic water splitting using surface plasmons in hybrid nanoparticles 审中-公开
标题翻译：通过使用混合纳米粒子中的表面等离子体激元的光催化水分解实现高效氢生产
公开(公告)号：US20120145532A1
公开(公告)日：2012-06-14
申请号：US13374364
申请日：2011-12-23
申请人： Gennady A. Smolyakov , Marek A. Osinski
发明人： Gennady A. Smolyakov , Marek A. Osinski
IPC分类号： C01B3/02 , B01J23/50 , B01J23/52 , B01J23/42 , B01J23/89 , B01J21/06 , B01J23/20 , B01J27/04 , B01J19/12 , B01J35/02 , B01J23/44 , B82Y30/00
CPC分类号： C01B3/042 , B01J21/063 , B01J23/60 , B01J23/6484 , B01J23/80 , B01J23/8474 , B01J35/0013 , B01J35/004 , B01J35/008 , B01J35/0086 , B01J37/035 , Y02E60/364 , Y02P20/134
摘要： Photocatalytic water splitting is employed as a method to directly obtain clean hydrogen from solar radiation by using hybrid nanoparticles with metallic cores and semiconductor photocatalytic shells. Efficient unassisted overall photocatalytic splitting of water is based on resonant absorption from surface plasmon in metal core/semiconductor shell hybrid nanoparticles, which can extend the absorption spectra further towards the visible-near infrared range, thus dramatically increasing the solar energy conversion efficiency. When used in combination with scintillator nanoparticles, the hybrid photocatalytic nanoparticles can be used for conversion of nuclear energy into hydrogen.
摘要翻译：采用光催化水分解法，通过使用金属核和半导体光催化壳的混合纳米粒子直接从太阳辐射获得清洁氢。水的有效无辅助整体光催化分解是基于金属核/半导体壳混合纳米粒子中表面等离子体激元的共振吸收，这可以将吸收光谱进一步扩展到可见光近红外范围，从而大大提高太阳能转换效率。当与闪烁体纳米颗粒组合使用时，杂化光催化纳米颗粒可用于将核能转化为氢。

8. 发明授权

US5052016A Resonant-periodic-gain distributed-feedback surface-emitting semiconductor laser 失效
标题翻译：共振周期增益分布式反馈表面发射半导体激光器
公开(公告)号：US5052016A
公开(公告)日：1991-09-24
申请号：US526083
申请日：1990-05-18
申请人： Mohammad Mahbobzadeh , Marek A. Osinski
发明人： Mohammad Mahbobzadeh , Marek A. Osinski
IPC分类号： H01S5/04 , H01S5/042 , H01S5/12 , H01S5/183 , H01S5/20 , H01S5/343 , H01S5/42
CPC分类号： B82Y20/00 , H01S5/1228 , H01S5/18383 , H01S5/423 , H01S3/0959 , H01S5/04 , H01S5/041 , H01S5/18341 , H01S5/18358 , H01S5/2059 , H01S5/34313
摘要： A resonant-periodic-gain distributed-feedback surface-emitting semiconductor laser has a resonator with an axis perpendicular to the plane of the substrate. The resonator comprises a stack of distributed feedback elements, each consisting of a spacer region and a very thin gain element positioned at an antinode of a standing wave inside the resonator at a designed wavelength. Each gain element consists of one or a group of closely spaced quantum-well layers. Each spacer, separating two adjacent gain elements, consists of two intermediate-and low-refractive-index layers, each layer of the spacer having an optical thickness approximately equal to a quarter of the designed wavelength. The refractive index of each of the gain elements is higher than that of the spacer materials. The device can be surrounded by a material of refractive index lower than all materials comprising the device for better confinement of carriers and control of guided modes of radiation. The structure can be directly pumped either optically or with an electron beam. Also, various well known schemes for electrical pumping can be utilized. The devices can be arranged to form one- or two-dimensional arrays.
摘要翻译：谐振周期增益分布式反馈表面发射半导体激光器具有垂直于衬底平面的轴的谐振器。谐振器包括分布反馈元件的堆叠，每个分组反馈元件由设计在波长的谐振器内的驻波的波腹的间隔区域和非常薄的增益元件组成。每个增益元件由一个或一组紧密间隔的量子阱层组成。分离两个相邻增益元件的每个间隔件由两个中间和低折射率层组成，间隔物的每个层的光学厚度近似等于设计波长的四分之一。每个增益元件的折射率高于间隔物材料的折射率。该装置可以被折射率低于包含装置的所有材料的材料包围，以便更好地约束载体并控制导向的辐射模式。该结构可以直接泵浦光学或电子束。此外，可以利用各种众所周知的用于电泵送的方案。这些装置可以被布置成形成一维或二维阵列。

9. 发明授权

US09354062B2 Rotation-sensitive semiconductor ring laser device using the nonlinear Sagnac effect 有权
标题翻译：旋转敏感半导体环形激光器件采用非线性Sagnac效应
公开(公告)号：US09354062B2
公开(公告)日：2016-05-31
申请号：US13987911
申请日：2013-09-16
申请人： Marek A. Osinski , Petr G. Eliseev , Edward W. Taylor
发明人： Marek A. Osinski , Petr G. Eliseev , Edward W. Taylor
IPC分类号： G01C19/72 , H01S3/102 , G02F1/35 , G01C19/66
CPC分类号： G01C19/727 , G01C19/66 , G02F1/3519 , H01S3/1028 , H01S5/1071 , H01S5/4068
摘要： Method and apparatus embody a rotation sensor including one or more ring lasers designed to utilize a nonlinear Sagnac effect, a passive waveguide arrangement, and a photodetector arrangement to receive the outcoupled light and to detect rotation of the sensor; wherein these components are arranged into a monolithically integrated optoelectronic integrated circuit on a single substrate. The method and apparatus can include seeding a stable, rotation -insensitive, strong (driving) wave using a single-frequency edge emitting laser monolithically integrated on the same substrate.
摘要翻译：方法和装置包括旋转传感器，其包括设计成利用非线性Sagnac效应的一个或多个环形激光器，无源波导装置和用于接收输出耦合的光并检测传感器的旋转的光电检测器装置; 其中这些部件被布置在单个基板上的单片集成光电集成电路中。该方法和装置可以包括使用单一集成在同一衬底上的单频边缘发射激光器接种稳定的，旋转敏感的强（驱动）波。

10. 发明授权

US08680469B1 Nanocrystalline optically-based neutron irradiation history sensor 有权
标题翻译：纳米晶体光子中子辐射历史传感器
公开(公告)号：US08680469B1
公开(公告)日：2014-03-25
申请号：US13385457
申请日：2012-02-21
申请人： Nathan J. Withers , Marek A. Osinski , Gennady A. Smolyakov
发明人： Nathan J. Withers , Marek A. Osinski , Gennady A. Smolyakov
IPC分类号： G01T3/08
CPC分类号： G01T3/00
摘要： A neutron irradiation history sensor and detection method for detection of thermal neutrons exploit transmutation of 164Dy into 165Ho and 166Er and significant differences in optical properties of Dy, Ho, and Er in order to enable detection of relative fractions of Dy, Ho, and Er and thus the degree and timing of prior thermal neutron exposure that has occurred, providing a tamper-proof forensic record of the prior thermal neutron exposure. The irradiation history sensor and detection method advantageously employ Dy-containing nanocrytals (NCs) residing in a transparent host.
摘要翻译：用于探测热中子的中子辐射历史传感器和检测方法利用164Dy的转变为165Ho和166Er，并且Dy，Ho和Er的光学性质有显着差异，以便能够检测Dy，Ho和Er的相对分数，因此已经发生了先前的热中子暴露的程度和时间，提供了先前的热中子暴露的防篡改取证记录。照射历史传感器和检测方法有利地使用驻留在透明主体中的含Dy纳米颗粒（NC）。

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