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    • 2. 发明申请
    • System and method for continuously transferring and processing liquids
    • 用于连续转移和处理液体的系统和方法
    • US20070086923A1
    • 2007-04-19
    • US11249192
    • 2005-10-13
    • William LiRongchang XinElgardo EchevarriaJohn Mitchell
    • William LiRongchang XinElgardo EchevarriaJohn Mitchell
    • B01L3/02
    • B01L3/0203B01L2200/0684B01L2200/16B01L2400/0487G01N35/1002Y10T436/2575
    • A liquid transfer system for transferring liquid from a plurality of containers to a plurality of destinations comprises a plurality of inlet valves. Each inlet valve is operable between an open position allowing liquid from a container to be drawn into the system and a closed position blocking liquid from a container from being drawn into the system. Liquid drawn from each of the liquid containers is delivered to a buffer chamber designed to degas the liquid in the buffer chamber. The buffer chamber leads to a vented feeder chamber that is also adapted to retain a volume of liquid. A chamber connection valve is provided between the buffer chamber and the feeder chamber to allow or block the flow of liquid between the buffer chamber and the feeder chamber. The feeder chamber is connected to a plurality of distribution valves operable to deliver liquid to a plurality of destinations.
    • 用于将液体从多个容器传送到多个目的地的液体传送系统包括多个入口阀。 每个入口阀可以在允许来自容器的液体被吸入系统的打开位置和封闭位置之间操作,该封闭位置阻止液体从容器被吸入系统。 从每个液体容器抽出的液体被输送到设计成使缓冲室中的液体脱气的缓冲室。 缓冲室通向通风的进料室,其也适于保持一定体积的液体。 腔室连接阀设置在缓冲室和进料室之间,以允许或阻止液体在缓冲室和给料室之间的流动。 进料室连接到可操作以将液体输送到多个目的地的多个分配阀。
    • 3. 发明申请
    • Method and apparatus for controlling reaction temperature in bio-chemical instruments
    • 用于控制生物化学仪器中反应温度的方法和装置
    • US20070183945A1
    • 2007-08-09
    • US11349445
    • 2006-02-07
    • William LiRongchang XinWing PangDobson Okawa
    • William LiRongchang XinWing PangDobson Okawa
    • B01J19/00
    • G01N1/38B01F13/0222B01F13/0233B01J2219/00495B01L7/00G01N2035/00425
    • Method and apparatus for controlling the temperature of one or more reaction vessels in a bio-chemical analyzer comprises a heat-exchange block, preferably made of cast aluminum or the like, and a thermoelectric device for heating or cooling the block to within a desired temperature range. The heat-transfer block cradles one or more reaction vessels in a thermal energy-transferring relationship, and further supports, in a thermal energy-transferring relationship, one or more fluid conduits serving to transmit a liquid or gas to the interior of the reaction vessels. Preferably, the heat-transfer block is cast from aluminum, and the fluid conduits are disposed inside the casting. By supporting the reaction vessel(s) and fluid conduit(s) in a common block, a single thermoelectric device and controller can be used to simultaneously control the respective temperatures of multiple fluid reagents and/or gases, as well as one or more reaction vessels, thereby reducing the power requirements of the thermal control system.
    • 用于控制生物化学分析仪中一个或多个反应容器的温度的方法和装置包括优选由铸铝等制成的热交换块和用于将块加热或冷却至所需温度的热电装置 范围。 热传递块以热能传递关系支撑一个或多个反应容器,并且在热能传递关系中进一步支撑用于将液体或气体传输到反应容器内部的一个或多个流体导管 。 优选地,传热块从铝铸造,并且流体导管设置在铸件内部。 通过将反应容器和流体导管支撑在共同的块中,可以使用单个热电装置和控制器来同时控制多个流体试剂和/或气体的相应温度,以及一个或多个反应 容器,从而降低了热控制系统的功率要求。
    • 5. 发明申请
    • Method and apparatus for maximizing liquid aspiration from small vessels
    • 从小血管最大化液体抽吸的方法和装置
    • US20070012123A1
    • 2007-01-18
    • US11183145
    • 2005-07-15
    • William LiMarco ZuletaPablo LarreaSantiago Galvez
    • William LiMarco ZuletaPablo LarreaSantiago Galvez
    • G01N1/22
    • G01N35/1016G01N2035/1025Y10T436/2575
    • Apparatus and method for aspirating liquid from a container, e.g., a test tube or other vessel, includes apparatus for sensing that an aspiration probe tip is contacting the inside bottom wall of the container, whereby a maximum volume of liquid can be aspirated from the container. According to the invention, an encoder is mounted on the driven member of a motor (e.g., on a rotatably-driven drive shaft or a nut of a stepper or D.C. motor, or on a linearly-driven shaft of a linear actuator) used to rectilinearly advance the probe tip into the container. Such encoder produces a series of pulses indicating the speed and/or linear position of the probe tip. A motor controller responds to a predetermined change in pattern of pulses from the encoder indicating that movement of the probe tip has been resisted by the vessel bottom, whereby further movement of the driven member and of the probe connected thereto is arrested, and the probe tip remains in contact with the vessel bottom.
    • 用于从容器(例如试管或其他容器)吸出液体的装置和方法包括用于感测吸入探针尖端接触容器的内底壁的装置,由此可以从容器中吸出最大体积的液体 。 根据本发明,编码器安装在电动机的从动构件上(例如,在可旋转驱动的驱动轴或步进或直流电动机的螺母上,或在线性致动器的直线驱动轴上) 将探针尖端直线推入容器。 这种编码器产生一系列指示探针尖端的速度和/或线性位置的脉冲。 马达控制器响应来自编码器的脉冲图案的预定变化,指示探针尖端的运动已经被血管底部抵抗,从而阻止从动构件和与其连接的探针的进一步运动,并且探针尖端 保持与血管底部接触。
    • 7. 发明授权
    • Embedded bio-sensor system
    • 嵌入式生物传感器系统
    • US07125382B2
    • 2006-10-24
    • US10849614
    • 2004-05-20
    • Peter ZhouDexing PangWilliam Li
    • Peter ZhouDexing PangWilliam Li
    • A61B5/00A61B5/05
    • A61B5/14865A61B5/0031A61B5/14532A61B2562/08G06F19/00G06F19/3418
    • Provided is a bio-sensor system which utilizes radio frequency identification technology and which includes a remote transponder in wireless communication with an implantable passively-powered on-chip transponder. The bio-sensor system is specifically adapted to provide a substantially stable and precise sensor reference voltage to a sensor assembly that is included with the on-chip transponder. The remote transponder is also configured to remotely receive data representative of a physiological parameter of the patient as well as identification data and may enable readout of one or more of the physiological parameters that are measured, processed and transmitted by the on-chip transponder upon request by the remote transponder. The precision and stability of the sensor reference voltage is enhanced by the specific circuit architecture of the glucose sensor to allow for relatively accurate measurement of the physiological parameter such as measurement of glucose concentration by a glucose sensor without the use of a microprocessor.
    • 提供了一种利用射频识别技术的生物传感器系统,其包括与可植入式被动供电的片上转发器进行无线通信的远程转发器。 生物传感器系统特别地适于向片上转发器附带的传感器组件提供基本上稳定和精确的传感器参考电压。 远程转发器还被配置为远程接收表示患者的生理参数的数据以及识别数据,并且可以使得能够读出由片上应答器根据请求测量,处理和传输的一个或多个生理参数 由远程转发器。 传感器参考电压的精度和稳定性通过葡萄糖传感器的具体电路结构得到增强,以允许相对精确地测量生理参数,例如葡萄糖传感器测量葡萄糖浓度而不使用微处理器。
    • 8. 发明授权
    • Light refraction illumination device
    • 光折射照明装置
    • US08029157B2
    • 2011-10-04
    • US12336352
    • 2008-12-16
    • William LiJack Li
    • William LiJack Li
    • F21S4/00F21V21/00
    • F21V5/048F21V13/04F21Y2115/10G02B19/0028G02B19/0066Y10S362/80
    • In an embodiment, a light refraction illumination device is disclosed. The light refraction illumination device may comprise or include a support member, and a plurality of lenses associated with the support member, wherein each lens from among the plurality of lenses may comprise or include a plurality of concave surfaces. The light refraction illumination device may further comprise or include at least one light source associated with the support member, wherein the at least one light source is configured to emit light, and wherein the at least one light source is positioned relative to the plurality of lenses such that the light is configured to travel through the plurality of concave surfaces.
    • 在一个实施例中,公开了一种光折射照明装置。 光折射照明装置可以包括或包括支撑构件和与支撑构件相关联的多个透镜,其中来自多个透镜中的每个透镜可以包括或包括多个凹面。 光折射照明装置还可以包括或包括与支撑构件相关联的至少一个光源,其中所述至少一个光源被配置为发射光,并且其中所述至少一个光源相对于所述多个透镜定位 使得所述光被配置成行进通过所述多个凹面。