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1. 发明申请

US20050169998A1 Stabilizing cgmp in aqueous formulation 失效
标题翻译：在水性配方中稳定cgmp
公开(公告)号：US20050169998A1
公开(公告)日：2005-08-04
申请号：US10506727
申请日：2003-01-16
申请人： Marcel Braun , Peter Erdmann
发明人： Marcel Braun , Peter Erdmann
IPC分类号： A61K8/64 , A61Q11/00 , A61K31/7076 , A61K9/14 , C07H19/22
CPC分类号： A61K8/64 , A61Q11/00
摘要： A cGMP containing aqueous composition exhibiting a reduced off-flavor even after extended storage, comprising a hydrophobic resin; and an agent, that chemically blocks functional groups in cGMP. Methods of preparing and using the product are also provided.
摘要翻译：含有CGMP的含水组合物，即使在延长储存后也显示减少的异味，包含疏水性树脂; 以及在cGMP中化学阻断官能团的试剂。还提供了制备和使用该产品的方法。

2. 发明授权

US07169757B2 Stabilizing cGMP in aqueous formulation 失效
标题翻译：在水性制剂中稳定cGMP
公开(公告)号：US07169757B2
公开(公告)日：2007-01-30
申请号：US10506727
申请日：2003-01-16
申请人： Marcel Braun , Peter Erdmann
发明人： Marcel Braun , Peter Erdmann
IPC分类号： A61K38/17
CPC分类号： A61K8/64 , A61Q11/00
摘要： A cGMP containing aqueous composition exhibiting a reduced off-flavor even after extended storage, comprising a hydrophobic resin; and an agent, that chemically blocks functional groups in cGMP. Methods of preparing and using the product are also provided.
摘要翻译：含有CGMP的含水组合物，即使在延长储存后也显示减少的异味，包含疏水性树脂; 以及在cGMP中化学阻断官能团的试剂。还提供了制备和使用该产品的方法。

3. 发明授权

US08738305B2 Method for detecting blockage in a Coriolis flow measuring device 有权
标题翻译：检测科里奥利流量测量装置堵塞的方法
公开(公告)号：US08738305B2
公开(公告)日：2014-05-27
申请号：US12662817
申请日：2010-05-05
申请人： Alfred Rieder , Wolfgang Drahm , Hao Zhu , Marcel Braun
发明人： Alfred Rieder , Wolfgang Drahm , Hao Zhu , Marcel Braun
IPC分类号： G01F7/00
CPC分类号： G01F1/8436 , G01F1/8477 , G01F25/0007
摘要： A method for detecting blockage of a measuring tube of a Coriolis flow measuring device, which has at least two measuring tubes. For this, the at least two measuring tubes are excited by at least one exciter to execute mechanical oscillations, mechanical oscillations of the measuring tubes are registered by at least one sensor and at least one measurement signal representing the mechanical oscillations is produced. At least one produced measurement signal is analyzed for the occurrence of a deviation of a resonance frequency of one measuring tube relative to a resonance frequency of the at least one other measuring tube. In case such a deviation occurs, blockage of a measuring tube is established.
摘要翻译：一种用于检测具有至少两个测量管的科里奥利流量测量装置的测量管阻塞的方法。为此，至少两个测量管由至少一个激励器激发以执行机械振荡，由至少一个传感器记录测量管的机械振荡，并且产生表示机械振荡的至少一个测量信号。分析至少一个产生的测量信号，以发现一个测量管的谐振频率相对于至少另一个测量管的谐振频率的偏差的发生。在发生这种偏差的情况下，建立测量管的堵塞。

4. 发明申请

US20140087021A1 MILK OLIGOSACCHARIDE-GALACTOOLIGOSACCHARIDE COMPOSITION FOR INFANT FORMULA CONTAINING THE SOLUBLE OLIGOSACCHARIDE FRACTION PRESENT IN MILK, AND HAVING A LOW LEVEL OF MONOSACCHARIDES, AND A PROCESS TO PRODUCE THE COMPOSITION 审中-公开
标题翻译：用于含有可溶性低聚葡萄糖分泌物的哺乳动物制剂，含有低水平的单加糖的制造低密度脂蛋白胆固醇组合物，以及生产组合物的方法
公开(公告)号：US20140087021A1
公开(公告)日：2014-03-27
申请号：US14118941
申请日：2012-05-23
申请人： Rafael Berrocal , Marcel Braun , Agustin Cevallos , Vanessa Marie , Gregoire Ricard
发明人： Rafael Berrocal , Marcel Braun , Agustin Cevallos , Vanessa Marie , Gregoire Ricard
IPC分类号： A23L1/29
CPC分类号： C12P19/04 , A23C2210/206 , A23L33/135 , A23L33/21 , A23L33/40 , A23V2002/00 , C12P19/14 , C12Y302/01023 , C12Y302/01032 , A23V2200/3202 , A23V2200/32 , A23V2200/304
摘要： The invention discloses an oligosaccharide mixture derived from cow's milk that can be easily spray dried comprising (a) a soluble oligosaccharide population which is the same as that of soluble oligosaccharides found in cow's milk and (b) β-galactooligosaccharides formed by the action of β-galacotsidase on lactose and the milk oligosaccharides. The mixture having a total monosaccharide content of less than 5% w/v and a lactose:oligosaccharide ratio of less than 20. A process for obtaining such a mixture, which includes a nanofiltration step, is disclosed. Nutritional compositions, especially infant formula, comprising said oligosaccharide mixture are also disclosed.
摘要翻译：本发明公开了一种衍生自牛奶的寡糖混合物，其可以容易地喷雾干燥，包括（a）可溶性寡糖群体，其与在牛奶中发现的可溶性低聚糖相同，和（b）通过以下方式形成的半乳寡糖：乳糖上的乳酸和乳寡糖。公开了具有小于5％w / v的总单糖含量和小于20的乳糖：寡糖比的混合物。一种获得包括纳滤过程的混合物的方法。还公开了包含所述寡糖混合物的营养组合物，特别是婴儿配方食品。

5. 发明申请

US20130266689A1 FLAVOUR MODULATION BY BIO-PROCESSING USING CREAM-FLAVOUR FORMING BACTERIA STRAINS 审中-公开
标题翻译：通过生物加工使用CREAM-FLAVOR形成细菌菌株进行调味
公开(公告)号：US20130266689A1
公开(公告)日：2013-10-10
申请号：US13995431
申请日：2011-12-20
申请人： Marcel Braun
发明人： Marcel Braun
IPC分类号： A23C9/123 , C12R1/46 , C12N1/20
CPC分类号： A23C9/1234 , A23L27/25 , A23Y2220/31 , C12N1/20 , C12P7/26 , C12R1/46
摘要： A fermentation of a milk source with Lactococcus lactis subsp. lactis diacetylactis (CNCM No. I-4404) or a Lactococcus lactis subsp. lactis diacetylactis (CNCM No. I-4405) to form a fermented milk product. The fermented milk product has at least a cream flavour and aroma. The fermented milk product can be in the form of a powder or a concentrate. The fermented milk product has applications in the food industry. A use of a lactic acid bacterium, Lactococcus lactis subsp. lactis diacetylactis (CNCM No. I-4404) or a Lactococcus lactis subsp. lactis diacetylactis (CNCM No. I-4405) for the manufacture of butter-cream flavouring milk ingredients containing at least one of diacetyl, acetoin and 3,4-dihydroxy-3,4-dimethyl-2,5-hexanedione.
摘要翻译：用乳酸乳球菌亚种发酵乳源乳酸二乙酰乳杆菌（CNCM No.I-4404）或乳酸乳球菌乳酸亚种乳酸二乙酰乳杆菌（CNCM No.I-4405）以形成发酵乳制品。发酵乳产品至少具有奶油味和香气。发酵乳产品可以是粉末或浓缩物的形式。发酵乳产品在食品工业中有应用。使用乳酸菌，乳酸乳球菌subsp。乳酸二乙酰乳杆菌（CNCM No.I-4404）或乳酸乳球菌乳酸亚种乳酸二乙酰乳杆菌（CNCM No.I-4405），用于制造含有二乙酰基，乙偶姻和3,4-二羟基-3,4-二甲基-2,5-己二酮中的至少一种的黄油奶油调味乳成分。

6. 外观设计

USD691241S1 Four tube coriollis flow meter 有权
标题翻译：四管科里奥利流量计
公开(公告)号：USD691241S1
公开(公告)日：2013-10-08
申请号：US29410442
申请日：2012-01-09
申请人： Marcel Braun
设计人： Marcel Braun

7. 发明申请

US20120167697A1 MEASURING TRANSDUCER OF THE VIBRATION TYPE AS WELL AS MEASURING SYSTEM FORMED THEREWITH 有权
标题翻译：振动类型的测量传感器，如其形成的测量系统
公开(公告)号：US20120167697A1
公开(公告)日：2012-07-05
申请号：US13341224
申请日：2011-12-30
申请人： Alfred Rieder , Christof Huber , Ennio Bitto , Christian Schutze , Marcel Braun
发明人： Alfred Rieder , Christof Huber , Ennio Bitto , Christian Schutze , Marcel Braun
IPC分类号： G01F1/84
CPC分类号： G01F1/8472 , G01F1/8413 , G01F1/8477 , G01F15/02 , G01F25/0007
摘要： A measuring transducer comprises: a housing, with an inlet-side flow divider having four flow openings, and an outlet-side end having four flow openings; a tube arrangement having four tubes connected to the flow dividers; and a first coupling element. An exciter mechanism for producing and/or maintaining mechanical oscillations of the four measuring tubes. The first coupling element includes a deformation body and four connecting struts, of which connected with a first strut end and with the first measuring tube, a second connecting strut is connected with a first strut end and with a second strut end with the second measuring tube, a third connecting strut and with a second strut end with the first measuring tube, and a fourth connecting strut is connected with a first strut end and with a second strut end with the fourth measuring tube.
摘要翻译：测量换能器包括：壳体，具有四个流动开口的入口侧分流器和具有四个流动开口的出口侧端部; 具有连接到分流器的四个管的管装置; 和第一耦合元件。用于产生和/或维持四个测量管的机械振荡的激励机构。第一联接元件包括变形体和四个连接支柱，其连接有第一支柱端和第一测量管，第二连接支柱与第一支柱端连接，第二支柱端与第二测量管，第三连接支柱和具有第一测量管的第二支柱端，第四连接支柱与第一支柱端连接，并且第二支柱端与第四测量管连接。

8. 发明授权

US06171621B2 Method for manufacturing a food based on a protein hydrolysate 失效
标题翻译：基于蛋白质水解产物制造食物的方法
公开(公告)号：US06171621B2
公开(公告)日：2001-01-09
申请号：US09208456
申请日：1998-12-10
申请人： Marcel Braun , Roland Schaedeli
发明人： Marcel Braun , Roland Schaedeli
IPC分类号： A23B422
CPC分类号： A23J3/346 , A23J3/343 , A23L33/18
摘要： A liquid food based on a protein hydrolysate and a method for manufacturing the liquid food. The food is manufactured by preparing a solution of a starting material containing proteins, adjusting the pH of the solution, sterilizing the solution, aseptically adding to the solution a proteolytic enzyme in an amount which is sufficient to produce the desired degree of hydrolysis, aseptically packaging the sterilized solution, and allowing the solution and enzyme to effect hydrolysis after packaging.
摘要翻译：基于蛋白质水解产物的液体食品和液体食品的制造方法。通过制备含有蛋白质的原料溶液，调节溶液的pH值，对溶液灭菌，无菌地向溶液中加入足以产生所需程度的水解的蛋白水解酶，无菌包装灭菌溶液，并使包装后的溶液和酶进行水解。

9. 发明授权

US08613227B2 Measuring transducer of vibration-type with four curved measuring tubes 有权
标题翻译：带四个弯曲测量管的振动型测量传感器
公开(公告)号：US08613227B2
公开(公告)日：2013-12-24
申请号：US12970072
申请日：2010-12-16
申请人： Ennio Bitto , Christof Huber , Marcel Braun , Alfred Rieder , Christian Schutze
发明人： Ennio Bitto , Christof Huber , Marcel Braun , Alfred Rieder , Christian Schutze
IPC分类号： G01F1/84
CPC分类号： G01F1/849 , G01F1/84 , G01F1/8413 , G01F1/8477 , G01F15/02 , G01F25/0007
摘要： The measuring transducer comprises: a transducer housing, of which an inlet-side, housing end is formed by means of a flow divider including four flow openings spaced, and an outlet-side, formed by means of a flow divider including four flow openings spaced, from one another. A tube arrangement including four curved measuring tubes connected to the flow dividers for guiding flowing medium along flow paths connected in parallel. Each measuring tubes opens with an inlet-side, measuring tube end into one of the flow openings of the flow divider and with an outlet-side, measuring tube end into one the flow openings of the flow divider. The two flow dividers are embodied and arranged in the measuring transducer, so that the tube arrangement extends both between a first and a second of the measuring tubes and between a third and a fourth of the measuring tubes. An imaginary longitudinal-section plane, with respect to which the tube arrangement is mirror symmetric and perpendicular to the imaginary longitudinal-section plane, an imaginary longitudinal-section plane, with respect to which the tube arrangement likewise is mirror symmetric. An electromechanical exciter mechanism of the measuring transducer serves for producing and/or maintaining mechanical oscillations of the four measuring tubes.
摘要翻译：测量传感器包括：换能器壳体，其入口侧的壳体端部通过分流器形成，该分流器包括四个流动间隔开的开口和出口侧，该分流器包括分流器，该分流器包括四个流动开口，从彼此。一种管装置，包括连接到分流器的四个弯曲测量管，用于沿着并联连接的流动路径引导流动介质。每个测量管打开，入口侧，测量管端部到分流器的一个流动开口中，并且出口侧的测量管端部分为一个分流器的流动开口。两个分流器被实施并布置在测量传感器中，使得管装置在第一和第二测量管之间以及在第三和第四测量管之间延伸。一个假想的纵截面平面，相对于该管的布置反射对称并垂直于假想的纵截面，一个假想的纵截面，相对于此，管布置同样是镜像对称的。测量传感器的机电激励器机构用于产生和/或维持四个测量管的机械振荡。

10. 发明授权

US08515691B2 Method for determining measuring tube wall thickness of a coriolis, flow measuring device 有权
标题翻译：用于确定科里奥利测量管壁厚度的方法，流量测量装置
公开(公告)号：US08515691B2
公开(公告)日：2013-08-20
申请号：US12662821
申请日：2010-05-05
申请人： Alfred Rieder , Wolfgang Drahm , Hao Zhu , Marcel Braun
发明人： Alfred Rieder , Wolfgang Drahm , Hao Zhu , Marcel Braun
IPC分类号： G01L5/00
CPC分类号： G01F1/8436
摘要： A method for determining tube wall thickness of at least one measuring tube of a Coriolis, flow measuring device, wherein the Coriolis, flow measuring device has an oscillatory system, which includes at least one measuring tube, and at least one exciter, by which the oscillatory system is excitable to execute mechanical oscillations. In the method, at least one excitation input variable of the at least one exciter and at least one response variable of oscillations of the oscillatory system caused thereby are registered. Additionally, a tube wall thickness of the at least one measuring tube is ascertained by inserting the excitation input variable and the response variable into a transfer equation.
摘要翻译：一种用于确定科里奥利流量测量装置的至少一个测量管的管壁厚度的方法，其中所述科里奥利流量测量装置具有包括至少一个测量管和至少一个激励器的振荡系统，振荡系统是可激励的，以执行机械振荡。在该方法中，记录至少一个激励器的至少一个激励输入变量和由此引起的振荡系统的振荡的至少一个响应变量。此外，通过将激励输入变量和响应变量插入传递方程来确定至少一个测量管的管壁厚度。

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