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1. 发明授权

US08826733B2 Sensored prosthetic component and method 有权
标题翻译：感觉假体成分及方法
公开(公告)号：US08826733B2
公开(公告)日：2014-09-09
申请号：US13406525
申请日：2012-02-27
申请人： Marc Stein , Andrew Chase , John Keggi , Noah Bonnheim , Natalie Burkhard , Philip Henson
发明人： Marc Stein , Andrew Chase , John Keggi , Noah Bonnheim , Natalie Burkhard , Philip Henson
IPC分类号： A61B5/22
CPC分类号： A61B5/4851 , A61B5/0008 , A61B5/0022 , A61B5/0084 , A61B5/01 , A61B5/4509 , A61B5/4528 , A61B5/6846
摘要： A prosthetic component suitable for long-term implantation is provided. The prosthetic component includes electronic circuitry and sensors to measure a parameter of the muscular-skeletal system. The prosthetic component comprises a first structure having at least one support surface, a second structure having at least one feature configured to couple to bone. The electronic circuitry and sensors are hermetically sealed within the prosthetic component. Sensors can be used to monitor synovial fluid in proximity to the joint to determine joint health. The prosthetic component can include a temperature sensor or a pH sensor. The temperature or pH of the synovial fluid can be correlated to a variety of joint conditions. Measurements over time can be analyzed for trends. The temperature or pH can be calibrated for the patient. For example, calibration can be for temperature or pH of a patient healthy joint. The measurements are compared against this patient reference.
摘要翻译：提供了适合于长期植入的假体部件。假体部件包括用于测量肌肉 - 骨骼系统的参数的电子电路和传感器。假体部件包括具有至少一个支撑表面的第一结构，具有被配置为联接到骨的至少一个特征的第二结构。电子电路和传感器密封在假体部件内。传感器可用于监测靠近关节的滑液，以确定关节的健康状况。假体部件可以包括温度传感器或pH传感器。滑液的温度或pH可以与各种关节条件相关。随着时间的推移可以分析趋势。可以为患者校准温度或pH。例如，校准可以用于患者健康关节的温度或pH。将测量值与该患者参考值进行比较。

2. 发明授权

US08777877B2 Spine tool for measuring vertebral load and position of load 有权
标题翻译：用于测量椎体负荷和负荷位置的脊柱工具
公开(公告)号：US08777877B2
公开(公告)日：2014-07-15
申请号：US13242278
申请日：2011-09-23
申请人： Marc Stein , Andrew Chase
发明人： Marc Stein , Andrew Chase
IPC分类号： A61B5/103 , A61B5/117 , A61B17/56 , A61F5/04 , A61B17/58 , A61B17/60 , A61F2/00 , A61B17/70 , A61B17/88
CPC分类号： A61B17/885 , A61B17/025 , A61B17/86 , A61B34/20 , A61B34/25 , A61B90/06 , A61B2017/00221 , A61B2017/00473 , A61B2017/00477 , A61B2017/00734 , A61B2017/0256 , A61B2034/2048 , A61B2090/064 , A61F2/4455 , A61F2/4611 , A61F2/4657 , A61F2002/2835 , A61F2002/30011 , A61F2002/3085 , A61F2002/4475 , A61F2002/4666 , A61F2310/00023
摘要： A spine measurement system includes at least one spinal instrument and a remote system. The spinal instrument comprises a handle, a shaft, an accelerometer, a sensored head, and an electronic assembly. The sensored head includes one or more sensors that are operatively coupled to the electronic assembly. The sensored head can be inserted between vertebra and report vertebral conditions such as force, pressure, orientation and edge loading. A GUI of remote system can report position via the accelerometer to show spinal instrument relative to vertebral bodies as the instrument is placed in the inter-vertebral space. The system can report optimal prosthetic size and placement in view of the sensed load and location parameters including optional orientation, rotation and insertion angle along a determined insert trajectory.
摘要翻译：脊柱测量系统包括至少一个脊柱器械和远程系统。脊柱器械包括手柄，轴，加速度计，感应头和电子组件。感测头包括可操作地耦合到电子组件的一个或多个传感器。感觉头可以插入椎骨和报告椎体条件如力，压力，方向和边缘负荷之间。远程系统的GUI可以通过加速度计报告位置，以便当仪器放置在椎间空间中时，显示脊柱器械相对于椎体。鉴于感测的负载和位置参数，系统可以报告最佳的假体尺寸和位置，包括沿着确定的插入轨迹的可选取向，旋转和插入角度。

3. 发明授权

US08690888B2 Modular active spine tool for measuring vertebral load and position of load 有权
标题翻译：用于测量椎体负荷和负荷位置的模块化活动脊柱工具
公开(公告)号：US08690888B2
公开(公告)日：2014-04-08
申请号：US13242536
申请日：2011-09-23
申请人： Marc Stein , Andrew Chase
发明人： Marc Stein , Andrew Chase
IPC分类号： A61B17/58 , A61B17/60 , A61F2/00
CPC分类号： A61B17/885 , A61B17/025 , A61B17/86 , A61B34/20 , A61B34/25 , A61B90/06 , A61B2017/00221 , A61B2017/00473 , A61B2017/00477 , A61B2017/00734 , A61B2017/0256 , A61B2034/2048 , A61B2090/064 , A61F2/4455 , A61F2/4611 , A61F2/4657 , A61F2002/2835 , A61F2002/30011 , A61F2002/3085 , A61F2002/4475 , A61F2002/4666 , A61F2310/00023
摘要： A spine measurement system includes a plurality of sensored heads, a spinal instrument, and a remote system. The spinal instrument comprises a handle, a shaft, sensored heads, and a module. The sensored heads includes one or more sensors that couple to module and each has a different height. The module includes an electronic assembly for receiving, processing, and sending quantitative data from sensors in sensored heads. The module can be coupled to and removed from handle. Similarly, sensored heads can be coupled to and removed from shaft. A sensored head can be inserted between vertebra and report vertebral conditions such as force, pressure, orientation and edge loading. A GUI of remote system can display a workflow and report load and position of load during the workflow.
摘要翻译：脊柱测量系统包括多个感测头，脊髓器械和远程系统。脊柱器械包括手柄，轴，感应头和模块。感测头包括耦合到模块并且每个具有不同高度的一个或多个传感器。该模块包括用于从感应头中的传感器接收，处理和发送定量数据的电子组件。该模块可以与手柄耦合并从手柄移除。类似地，感应头可以联接到轴并从轴移除。可以在椎骨和报告椎体条件（如力，压力，方向和边缘负荷）之间插入感觉头。远程系统的GUI可以在工作流程中显示工作流程并报告负载和负载位置。

4. 发明申请

US20120226360A1 PROSTHETIC COMPONENT FOR MONITORING JOINT HEALTH 有权
标题翻译：用于监测关节健康的预防组件
公开(公告)号：US20120226360A1
公开(公告)日：2012-09-06
申请号：US13406519
申请日：2012-02-27
申请人： Marc Stein , Andrew Chase
发明人： Marc Stein , Andrew Chase
IPC分类号： A61F2/38 , A61B5/00 , A61B5/103
CPC分类号： A61B8/0875 , A61B5/0082 , A61B5/01 , A61B5/1032 , A61B5/14539 , A61B5/4509 , A61B5/4528 , A61B5/4851 , A61B5/6846 , A61B8/58
摘要： A prosthetic component suitable for long-term implantation is provided. The prosthetic component includes electronic circuitry and sensors to measure a parameter of the muscular-skeletal system. The prosthetic component comprises a first structure having at least one support surface, a second structure having at least one feature configured to couple to bone, and at least one sensor. The electronic circuitry and sensors are hermetically sealed within the prosthetic component. The prosthetic component includes at least on transmissive region. The transmissive region can be located in a region that has exposure to a region outside the joint. The transmissive region can comprise glass. One or more sensors can be used to monitor synovial fluid in proximity to the joint to determine joint health. The transmissive region can be used to support communication between the electronic circuitry and remote system.
摘要翻译：提供了适合于长期植入的假体部件。假肢部件包括用于测量肌肉骨骼系统的参数的电子电路和传感器。假体部件包括具有至少一个支撑表面的第一结构，具有被配置为联接到骨骼的至少一个特征的第二结构以及至少一个传感器。电子电路和传感器密封在假体部件内。假体部件至少包括透射区域。透射区域可以位于暴露于接头外部区域的区域中。透射区域可以包括玻璃。一个或多个传感器可用于监测靠近关节的滑液，以确定关节的健康状况。透射区域可以用于支持电子电路和远程系统之间的通信。

5. 发明申请

US20120226359A1 SHIELDED PROSTHETIC COMPONENT 有权
标题翻译：屏蔽前置元件
公开(公告)号：US20120226359A1
公开(公告)日：2012-09-06
申请号：US13406515
申请日：2012-02-27
申请人： Marc Stein , Andrew Chase
发明人： Marc Stein , Andrew Chase
IPC分类号： A61F2/38 , A61B5/11
CPC分类号： A61F2/4657 , A61B5/4509 , A61B5/4528 , A61B5/6846
摘要： A prosthetic component suitable for long-term implantation is provided. The prosthetic component measures a parameter of the muscular-skeletal system is disclosed. The prosthetic component comprises a first structure having at least one support surface, a second structure having at least one feature configured to couple to bone, and at least one sensor. The electronic circuitry and sensors are hermetically sealed within the prosthetic component. The sensor couples to the support surface of the first structure. The first and second structure are coupled together housing the at least one sensor. The first and second structures comprises steel, titanium, cobalt or an alloy thereof. At least one of the first or second structures is coupled to ground to shield the sensor from parasitic coupling. The at least one sensor can be a pressure sensor for measuring load and position of load.
摘要翻译：提供了适合于长期植入的假体部件。公开了假肢部件测量肌肉骨骼系统的参数。假体部件包括具有至少一个支撑表面的第一结构，具有被配置为耦合到骨骼的至少一个特征的第二结构以及至少一个传感器。电子电路和传感器密封在假体部件内。传感器耦合到第一结构的支撑表面。第一和第二结构联接在一起，容纳至少一个传感器。第一和第二结构包括钢，钛，钴或其合金。第一或第二结构中的至少一个耦合到地以屏蔽传感器与寄生耦合。至少一个传感器可以是用于测量负载和负载位置的压力传感器。

6. 发明申请

US20120220839A1 PROSTHETIC COMPONENT FOR MONITORING SYNOVIAL FLUID AND METHOD 有权
标题翻译：用于监测对流液体和方法的前置部件
公开(公告)号：US20120220839A1
公开(公告)日：2012-08-30
申请号：US13406523
申请日：2012-02-27
申请人： Marc Stein , Andrew Chase
发明人： Marc Stein , Andrew Chase
IPC分类号： A61B5/00
CPC分类号： A61B5/14507 , A61B5/1455 , A61B5/4509 , A61B5/4528 , A61B5/6846
摘要： A prosthetic component suitable for long-term implantation is provided. The prosthetic component includes electronic circuitry and sensors to measure a parameter of the muscular-skeletal system. The prosthetic component comprises a first structure having at least one support surface, a second structure having at least one feature configured to couple to bone, and at least one sensor. The electronic circuitry and sensors are hermetically sealed within the prosthetic component. One or more sensors can be used to monitor synovial fluid in proximity to the joint to determine joint health. The prosthetic component includes a transmissive region. One or more optical sensors are mounted in proximity to the transmissive region. Periodic measurements of the synovial fluid are measured through the transmissive region. The measurements can include color and turbidity of the synovial fluid. The color and turbidity data can be compared against known data to determine joint status.
摘要翻译：提供了适合于长期植入的假体部件。假肢部件包括用于测量肌肉骨骼系统的参数的电子电路和传感器。假体部件包括具有至少一个支撑表面的第一结构，具有被配置为耦合到骨骼的至少一个特征的第二结构以及至少一个传感器。电子电路和传感器密封在假体部件内。一个或多个传感器可用于监测靠近关节的滑液，以确定关节的健康状况。假体部件包括透射区域。一个或多个光学传感器安装在透射区域附近。通过透射区域测量滑液的周期性测量。测量可以包括滑液的颜色和浊度。可以将颜色和浊度数据与已知数据进行比较以确定联合状态。

7. 发明申请

US20120190940A1 SENSORED PROSTHETIC COMPONENT AND METHOD 有权
标题翻译：传感器的前置元件和方法
公开(公告)号：US20120190940A1
公开(公告)日：2012-07-26
申请号：US13406525
申请日：2012-02-27
申请人： Marc Stein , Andrew Chase
发明人： Marc Stein , Andrew Chase
IPC分类号： A61B5/01 , A61B5/00
CPC分类号： A61B5/4851 , A61B5/0008 , A61B5/0022 , A61B5/0084 , A61B5/01 , A61B5/4509 , A61B5/4528 , A61B5/6846
摘要： A prosthetic component suitable for long-term implantation is provided. The prosthetic component includes electronic circuitry and sensors to measure a parameter of the muscular-skeletal system. The prosthetic component comprises a first structure having at least one support surface, a second structure having at least one feature configured to couple to bone. The electronic circuitry and sensors are hermetically sealed within the prosthetic component. Sensors can be used to monitor synovial fluid in proximity to the joint to determine joint health. The prosthetic component can include a temperature sensor or a pH sensor. The temperature or pH of the synovial fluid can be correlated to a variety of joint conditions. Measurements over time can be analyzed for trends. The temperature or pH can be calibrated for the patient. For example, calibration can be for temperature or pH of a patient healthy joint. The measurements are compared against this patient reference.
摘要翻译：提供了适合于长期植入的假体部件。假肢部件包括用于测量肌肉骨骼系统的参数的电子电路和传感器。假体部件包括具有至少一个支撑表面的第一结构，具有被配置为联接到骨的至少一个特征的第二结构。电子电路和传感器密封在假体部件内。传感器可用于监测靠近关节的滑液，以确定关节的健康状况。假体部件可以包括温度传感器或pH传感器。滑液的温度或pH可以与各种关节条件相关。随着时间的推移可以分析趋势。可以为患者校准温度或pH。例如，校准可以用于患者健康关节的温度或pH。将测量值与该患者参考值进行比较。

8. 发明申请

US20120152036A1 SHIELDED CAPACITOR SENSOR SYSTEM FOR MEDICAL APPLICATIONS AND METHOD 有权
标题翻译：用于医疗应用和方法的屏蔽电容传感器系统
公开(公告)号：US20120152036A1
公开(公告)日：2012-06-21
申请号：US13406510
申请日：2012-02-27
申请人： Marc Stein , Andrew Chase
发明人： Marc Stein , Andrew Chase
IPC分类号： G01L1/14
CPC分类号： A61F2/4657 , A61B5/076 , A61B5/4509 , A61B5/4528 , A61B5/6846 , A61B5/6847 , A61B17/1615 , A61B17/1666 , A61B2090/065 , A61B2562/0252 , A61B2562/182
摘要： A measurement system for measuring a parameter of the muscular-skeletal system is disclosed. The measurement system comprises a capacitor, a signal generator, a digital counter, counter register, a digital clock, a digital timer, and a data register. The sensor of the measurement system is the capacitor. The measurement system generates a repeating signal having a measurement cycle that corresponds to the capacitance of the capacitor. The capacitor comprises more than one capacitor mechanically in series. Electrically, the capacitor comprises more than one capacitor in parallel. In one embodiment, the capacitor includes a dielectric layer comprising polyimide. A force, pressure, or load is applied to the capacitor that elastically compresses the device. The capacitor is shielded from parasitic coupling and parasitic capacitance.
摘要翻译：公开了一种用于测量肌肉骨骼系统参数的测量系统。测量系统包括电容器，信号发生器，数字计数器，计数器寄存器，数字时钟，数字计时器和数据寄存器。测量系统的传感器是电容器。测量系统产生具有对应于电容器的电容的测量周期的重复信号。电容器包括多个串联的电容器。电气地，电容器包括多于一个并联的电容器。在一个实施例中，电容器包括包含聚酰亚胺的电介质层。力，压力或负载施加到弹性压缩装置的电容器上。电容器屏蔽寄生耦合和寄生电容。

9. 发明授权

US08784339B2 Spinal instrument for measuring load and position of load 有权
标题翻译：用于测量负载和负载位置的脊柱仪器
公开(公告)号：US08784339B2
公开(公告)日：2014-07-22
申请号：US13242830
申请日：2011-09-23
申请人： Marc Stein , Andrew Chase
发明人： Marc Stein , Andrew Chase
IPC分类号： A61B5/103 , A61B5/117 , A61B17/56 , A61F5/04 , A61B17/70 , A61B17/88
CPC分类号： A61B17/885 , A61B17/025 , A61B17/86 , A61B34/20 , A61B34/25 , A61B90/06 , A61B2017/00221 , A61B2017/00473 , A61B2017/00477 , A61B2017/00734 , A61B2017/0256 , A61B2034/2048 , A61B2090/064 , A61F2/4455 , A61F2/4611 , A61F2/4657 , A61F2002/2835 , A61F2002/30011 , A61F2002/3085 , A61F2002/4475 , A61F2002/4666 , A61F2310/00023
摘要： A spinal instrument includes sensors for measuring a parameter of the muscular-skeletal system. The spinal instrument includes a sensored head region that can be inserted into a spinal region. The spinal instrument comprises a housing, a housing, an electronic assembly, and a flexible interconnect. Housing includes a handle portion, a shaft portion, and a support structure. Similarly, housing includes a handle portion, a shaft portion, and a support structure. Furthermore, housing has a cavity and a lengthwise passage respectively for receiving electronic assembly and flexible interconnect. A sensored head region of spinal instrument includes an assembly stack for measuring load magnitude and position of load on the support structure and the support structure. The flexible interconnect couples the electronic assembly to the sensors.
摘要翻译：脊髓器械包括用于测量肌肉 - 骨骼系统参数的传感器。脊柱器械包括可以插入脊椎区域的感觉头部区域。脊柱器械包括壳体，壳体，电子组件和柔性互连件。壳体包括手柄部分，轴部分和支撑结构。类似地，壳体包括手柄部分，轴部分和支撑结构。此外，壳体具有分别用于接收电子组件和柔性互连的腔和纵向通道。脊柱器械的感觉头部区域包括用于测量载荷大小和载荷在支撑结构和支撑结构上的位置的组件叠层。柔性互连将电子组件耦合到传感器。

10. 发明授权

US08661893B2 Prosthetic component having a compliant surface 有权
标题翻译：具有柔顺表面的假体部件
公开(公告)号：US08661893B2
公开(公告)日：2014-03-04
申请号：US13406512
申请日：2012-02-27
申请人： Marc Stein , Andrew Chase
发明人： Marc Stein , Andrew Chase
IPC分类号： A61B5/22
CPC分类号： A61B5/4528 , A61B5/0031 , A61B5/01 , A61B5/076 , A61B5/1032 , A61B5/1036 , A61B5/4509 , A61B5/4571 , A61B5/4585 , A61B5/4851 , A61B5/6846 , A61B5/686 , A61B5/7225 , A61B2560/0209 , A61B2562/0247 , A61B2562/0252 , A61F2/389 , A61F2/4657 , A61F2/4684 , A61F2002/4666 , G01L1/255
摘要： A prosthetic component suitable for long-term implantation is provided. The prosthetic component measures a parameter of the muscular-skeletal system is disclosed. The prosthetic component comprises a first structure having at least one support surface, a second structure having at least one feature configured to couple to bone, and at least one sensor. The electronic circuitry and sensors are hermetically sealed within the prosthetic component. The sensor couples to the support surface of the first structure. The support surface of the first structure is compliant. The first and second structure are coupled together housing the at least one sensor. In one embodiment, the first and second structure are welded together forming the hermetic seal that isolates the at least one sensor from an external environment. The at least one sensor can be a pressure sensor for measuring load and position of load.
摘要翻译：提供了适合于长期植入的假体部件。公开了假肢部件测量肌肉骨骼系统的参数。假体部件包括具有至少一个支撑表面的第一结构，具有被配置为联接到骨骼的至少一个特征的第二结构以及至少一个传感器。电子电路和传感器密封在假体部件内。传感器耦合到第一结构的支撑表面。第一结构的支撑表面是顺从的。第一和第二结构联接在一起，容纳至少一个传感器。在一个实施例中，将第一和第二结构焊接在一起，形成将至少一个传感器与外部环境隔离的气密密封。至少一个传感器可以是用于测量负载和负载位置的压力传感器。

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