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1. 发明申请

US20060089836A1 System and method of signal pre-conditioning with adaptive spectral tilt compensation for audio equalization 审中-公开
标题翻译：用于音频均衡的自适应频谱倾斜补偿信号预处理的系统和方法
公开(公告)号：US20060089836A1
公开(公告)日：2006-04-27
申请号：US10970188
申请日：2004-10-21
申请人： Marc Boillot , Brian Adair , Joseph Friedman , Karl Mueller
发明人： Marc Boillot , Brian Adair , Joseph Friedman , Karl Mueller
IPC分类号： G10L21/00
CPC分类号： G10L19/26
摘要： Systems and methods for pre-conditioning a received audio signal prior to audio equalization of the audio signal are provided. The system (100) includes a spectral tilt estimator (110) for estimating a spectral tilt of the received audio signal, and a compensative filter synthesizer (115) for synthesizing a compensative filter based upon the spectral tilt estimated by the spectral tilt estimator. The filter comprises at least one compensative filter coefficient for mitigating the spectral tilt of the received audio signal prior to audio equalization of the audio signal.
摘要翻译：提供了在音频信号的音频均衡之前对接收到的音频信号进行预处理的系统和方法。系统（100）包括用于估计接收到的音频信号的频谱倾斜的频谱倾斜估计器（110）和用于基于由频谱倾斜估计器估计的频谱倾斜来合成补偿滤波器的补偿滤波器合成器（115）。滤波器包括至少一个补偿滤波器系数，用于在音频信号的音频均衡之前减轻接收到的音频信号的频谱倾斜。

2. 发明申请

US20070076908A1 MULTIPLE CHANNEL AUDIO ENCODER USING DIFFERENCE SIGNAL 审中-公开
标题翻译：多声道音频编码器使用差分信号
公开(公告)号：US20070076908A1
公开(公告)日：2007-04-05
申请号：US11469275
申请日：2006-08-31
申请人： Julio Castaneda , Brian Adair , Eric Penrod
发明人： Julio Castaneda , Brian Adair , Eric Penrod
IPC分类号： H04R5/02 , H04R1/02
CPC分类号： H04R1/245 , H04M1/60 , H04M1/72522 , H04R2400/01 , H04R2499/11
摘要： A wireless device (300) receives and captures multiple-channel audio signals and outputs the multiple-channel audio signals on at least one channel output stream (606). The wireless device (300) includes a microphone (401) for capturing a first audio channel and at least one speaker (402) for capturing additional audio channels. Each speaker has a switch (403) to enable the speaker to operate as an additional microphone for capturing at least one additional audio channel. The device also has a comparator (404), connected to a plurality of audio channels including the first audio channel and any additional audio channels, so that the comparator identifies which of the audio channels has a predetermined signal strength so as to identify one of the audio channels as a reference audio channel (406, 405). Additionally, in one embodiment, the comparator identifies which of the audio channels has a predetermined phase and identifies one of the audio channels as a reference phase channel (406, 405). The device also has an encoder (407) for receiving the plurality of audio channels to produce an output over at least one channel where the reference audio channel forms a reference signal and the audio channels other than the reference signal each form a delta signal from the reference channel.
摘要翻译：无线设备（300）接收并捕获多声道音频信号并在至少一个声道输出流（606）上输出多声道音频信号。无线设备（300）包括用于捕获第一音频通道的麦克风（401）和用于捕获附加音频通道的至少一个扬声器（402）。每个扬声器具有开关（403），以使扬声器能够作为用于捕获至少一个附加音频通道的附加麦克风来操作。该设备还具有连接到包括第一音频通道和任何附加音频通道的多个音频通道的比较器（404），使得比较器识别哪个音频通道具有预定的信号强度，以便识别音频频道作为参考音频频道（406,405）。另外，在一个实施例中，比较器识别哪个音频通道具有预定的相位，并且将一个音频通道识别为参考相位通道（406,405）。该设备还具有用于接收多个音频通道以在至少一个通道上产生输出的编码器（407），其中参考音频通道形成参考信号，并且除参考信号之外的音频通道各自形成来自参考通道。

3. 发明授权

US08338159B2 Chicken virus vaccine and diagnostic 有权
标题翻译：鸡病毒疫苗和诊断
公开(公告)号：US08338159B2
公开(公告)日：2012-12-25
申请号：US12087477
申请日：2007-01-04
申请人： Daniel Todd , Brian Adair , Mildred Wylie , Neris Ball
发明人： Daniel Todd , Brian Adair , Mildred Wylie , Neris Ball
IPC分类号： C12N7/01 , A61K39/21
CPC分类号： C07K14/005 , A61K39/00 , C12N2770/12022 , C12Q1/701
摘要： A novel astrovirus designated chicken astrovirus type 3 has been isolated and characterized. Nucleotide sequences and polypeptide sequences of this astrovirus are provided with uses of the same and the isolated astrovirus in assay kits and vaccines.
摘要翻译：已经分离和表征了一种称为3型鸡星状病毒的新型星状病毒。这种星状病毒的核苷酸序列和多肽序列提供其在测定试剂盒和疫苗中的用途和分离的星状病毒。

4. 发明申请

US20120087932A1 DIAGNOSTIC TEST FOR VIRUS 有权
标题翻译：病毒诊断测试
公开(公告)号：US20120087932A1
公开(公告)日：2012-04-12
申请号：US13259296
申请日：2010-03-31
申请人： Danny Todd , Victoria Smyth , Brian Adair
发明人： Danny Todd , Victoria Smyth , Brian Adair
IPC分类号： A61K39/00 , C07H21/04 , C07K14/00 , A61P37/04 , G01N33/53 , C07H21/00 , C12N15/63 , C12P21/00 , C12Q1/70 , C07K16/00
CPC分类号： C12Q1/701 , A01K2227/101 , A01K2267/02
摘要： Unique Avian Nephritis Virus (ANV) nucleic acid sequences have been determined. Primers and probes have been developed using the isolated nucleic acid sequences and a reverse transcription PCR has been developed to detect the presence of ANV in commercial flocks. Furthermore, use of the nucleic acid sequences and amino acids sequences encoded therefrom and antibodies to said amino acids is discussed.
摘要翻译：已经确定了独特的禽肾炎病毒（ANV）核酸序列。已经使用分离的核酸序列开发了引物和探针，并且开发了逆转录PCR以检测商业鸡群中ANV的存在。此外，讨论了使用由其编码的核酸序列和氨基酸序列和对所述氨基酸的抗体。

5. 发明申请

US20090092634A1 Chicken Virus Vaccine and Diagnostic 有权
标题翻译：鸡病毒疫苗和诊断
公开(公告)号：US20090092634A1
公开(公告)日：2009-04-09
申请号：US12087477
申请日：2007-01-04
申请人： Daniel Todd , Brian Adair , Mildred Wylie , Neris Ball
发明人： Daniel Todd , Brian Adair , Mildred Wylie , Neris Ball
IPC分类号： A61K39/12 , C12N7/00 , C07H21/02 , C12N15/63 , C12P21/00 , A61P31/12 , C12Q1/70 , C07K14/00 , C07K14/08 , A61K35/76
CPC分类号： C07K14/005 , A61K39/00 , C12N2770/12022 , C12Q1/701
摘要： A novel astrovirus designated chicken astrovirus type 3 has been isolated and characterised. Nucleotide sequences and polypeptide sequences of this astrovirus are provided with uses of the same and the isolated astrovirus in assay kits and vaccines.
摘要翻译：已经分离和表征了一种称为3型鸡星状病毒的新型星状病毒。这种星状病毒的核苷酸序列和多肽序列提供其在测定试剂盒和疫苗中的用途和分离的星状病毒。

6. 发明申请

US20060013423A1 Method and system for selective coupling of a communication unit to a hearing enhancement device 有权
标题翻译：用于将通信单元选择性地耦合到听力增强装置的方法和系统
公开(公告)号：US20060013423A1
公开(公告)日：2006-01-19
申请号：US10890006
申请日：2004-07-13
申请人： Alfred Wieczorek , Brian Adair
发明人： Alfred Wieczorek , Brian Adair
IPC分类号： H04R25/00 , H04R9/06 , H04R11/02
CPC分类号： H04M1/72591 , H04R25/554
摘要： The invention concerns a method (200) and system (100) for selectively coupling a communication unit (110) to a hearing enhancement device (112). The method includes the steps of—in the communication unit—selecting (212) between an acoustic coupling setting and an inductive coupling setting, in response to the selecting step, switching (214) an audio output of the communication unit to an acoustic coupling path (136) or an inductive coupling path (138), and outputting (226) through either the acoustic coupling path or the inductive coupling path an audio signal to the hearing enhancement device.
摘要翻译：本发明涉及用于将通信单元（110）选择性地耦合到听力增强设备（112）的方法（200）和系统（100）。该方法包括以下步骤：响应于选择步骤，在声耦合设置和电感耦合设置之间的通信单元选择（212）中，将通信单元的音频输出切换（214）到声耦合路径（136）或电感耦合路径（138），并且通过声耦合路径或电感耦合路径将音频信号输出（226）到听力增强设备。

7. 发明申请

US20050254661A1 Wireless device for capturing multiple channel audio 审中-公开
标题翻译：用于捕获多声道音频的无线设备
公开(公告)号：US20050254661A1
公开(公告)日：2005-11-17
申请号：US10845752
申请日：2004-05-14
申请人： Julio Castaneda , Brian Adair , Eric Penrod
发明人： Julio Castaneda , Brian Adair , Eric Penrod
IPC分类号： H04M1/60 , H04M1/725 , H04R1/24 , H04R5/00 , H04R5/02
CPC分类号： H04R1/245 , H04M1/60 , H04M1/72522 , H04R2400/01 , H04R2499/11
摘要： A wireless device (300) receives and captures multiple-channel audio signals and outputs the multiple-channel audio signals on at least one channel output stream (606). The wireless device (300) includes a microphone (401) for capturing a first audio channel and at least one speaker (402) for capturing additional audio channels. Each speaker has a switch (403) to enable the speaker to operate as an additional microphone for capturing at least one additional audio channel. The device also has a comparator (404), connected to a plurality of audio channels including the first audio channel and any additional audio channels, so that the comparator identifies which of the audio channels has a predetermined signal strength so as to identify one of the audio channels as a reference audio channel (406, 405). Additionally, in one embodiment, the comparator identifies which of the audio channels has a predetermined phase and identifies one of the audio channels as a reference phase channel (406, 405). The device also has an encoder (407) for receiving the plurality of audio channels to produce an output over at least one channel where the reference audio channel forms a reference signal and the audio channels other than the reference signal each form a delta signal from the reference channel.
摘要翻译：无线设备（300）接收并捕获多声道音频信号并在至少一个声道输出流（606）上输出多声道音频信号。无线设备（300）包括用于捕获第一音频通道的麦克风（401）和用于捕获附加音频通道的至少一个扬声器（402）。每个扬声器具有开关（403），以使扬声器能够作为用于捕获至少一个附加音频通道的附加麦克风来操作。该设备还具有连接到包括第一音频通道和任何附加音频通道的多个音频通道的比较器（404），使得比较器识别哪个音频通道具有预定的信号强度，以便识别音频频道作为参考音频频道（406,405）。另外，在一个实施例中，比较器识别哪个音频通道具有预定的相位，并且将一个音频通道识别为参考相位通道（406,405）。该设备还具有用于接收多个音频通道以在至少一个通道上产生输出的编码器（407），其中参考音频通道形成参考信号，并且除参考信号之外的音频通道各自形成来自参考通道。

8. 发明授权

US09702016B2 Diagnostic test for virus 有权
公开(公告)号：US09702016B2
公开(公告)日：2017-07-11
申请号：US13259296
申请日：2010-03-31
申请人： Danny Todd , Victoria Smyth , Brian Adair
发明人： Danny Todd , Victoria Smyth , Brian Adair
IPC分类号： A61K39/12 , C07H21/04 , C12N7/00 , C12Q1/70 , A61P31/12
CPC分类号： C12Q1/701 , A01K2227/101 , A01K2267/02
摘要： Unique Avian Nephritis Virus (ANV) nucleic acid sequences have been determined. Primers and probes have been developed using the isolated nucleic acid sequences and a reverse transcription PCR has been developed to detect the presence of ANV in commercial flocks. Furthermore, use of the nucleic acid sequences and amino acids sequences encoded therefrom and antibodies to said amino acids is discussed.

9. 发明申请

US20110236397A1 LIMITED PROTEOLYSIS OF CD2AP AND PROGRESSION OF RENAL DISEASE 审中-公开
标题翻译： CD2AP的有限分析和肾病的进展
公开(公告)号：US20110236397A1
公开(公告)日：2011-09-29
申请号：US13127839
申请日：2009-11-06
申请人： Jochen Reiser , Brian Adair
发明人： Jochen Reiser , Brian Adair
IPC分类号： A61K39/395 , A61K38/48 , A61K31/7088 , A61K38/02 , A61K38/43 , C12Q1/37 , C12Q1/02 , C07K14/47 , C12N15/63 , C07K16/18 , C12N9/00 , C12N9/64 , C12N9/14 , A61P13/12 , A61P3/10 , A61P7/00 , A61P35/00 , A61P31/00
CPC分类号： C07K16/18 , A61K38/4873 , C12N15/113 , C12N15/1137 , C12N2310/11 , C12N2310/14 , C12N2310/16 , C12Y304/23005 , G01N33/5044
摘要： Compositions which specifically block cathepsin L function in podocytes, compositions which protect cytoskeletal adaptor protein (CD2AP) for degradation, compositions which modulate expression or function of cytoskeletal adaptor protein (CD2AP), protect against renal diseases or disorders. Methods of treatment in vivo involve use of one or more compositions.
摘要翻译：特异性阻断组织蛋白酶L在足细胞中功能的组合物，保护细胞骨架衔接蛋白（CD2AP）进行降解的组合物，其调节细胞骨架衔接蛋白（CD2AP）的表达或功能的组合物，可防止肾脏疾病或病症。体内治疗方法涉及使用一种或多种组合物。

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