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1. 发明授权

US10167329B2 Stabilized insulin-like growth factor polypeptides 有权
公开(公告)号：US10167329B2
公开(公告)日：2019-01-01
申请号：US14651686
申请日：2013-12-16
申请人： Mara Fornaro , Thomas Huber , Mauro Zurini
发明人： Mara Fornaro , Thomas Huber , Mauro Zurini
IPC分类号： C07K14/65
摘要： This invention is in the field of IGF-1 modifications. In particular, it relates to modified IGF-polypeptides and modified IGF-1 precursor polypeptides wherein the cleavage of E-peptide is prevented. The invention also relates to the use of such polypeptides for treating muscle diseases and disorders.

2. 发明授权

US09789203B2 cKIT antibody drug conjugates 有权
公开(公告)号：US09789203B2
公开(公告)日：2017-10-17
申请号：US14774512
申请日：2014-03-12
申请人： Tinya Abrams , Steven Cohen , Christie P. Fanton , Catrin Finner , Thomas Huber , Kathy Miller , Siew Ho Schleyer , Kathrin Ulrike Tissot-Daguette
发明人： Tinya Abrams , Steven Cohen , Christie P. Fanton , Catrin Finner , Thomas Huber , Kathy Miller , Siew Ho Schleyer , Kathrin Ulrike Tissot-Daguette
IPC分类号： A61K39/395 , A61K47/48 , A61K39/00 , C07K16/32 , C07K16/28 , A61K31/537 , A61K45/06 , A61K47/12 , A61K47/26 , A61K49/00 , A61K49/16 , A61K51/10 , A61K9/00 , A61K9/19
CPC分类号： A61K47/6803 , A61K9/0019 , A61K9/19 , A61K31/537 , A61K45/06 , A61K47/12 , A61K47/26 , A61K47/6801 , A61K47/6849 , A61K47/6855 , A61K47/6857 , A61K47/6865 , A61K47/6867 , A61K47/6889 , A61K49/00 , A61K51/103 , A61K51/1093 , A61K2039/505 , C07K16/2803 , C07K16/2863 , C07K16/32 , C07K2317/14 , C07K2317/21 , C07K2317/24 , C07K2317/30 , C07K2317/33 , C07K2317/34 , C07K2317/55 , C07K2317/565 , C07K2317/73 , C07K2317/732 , C07K2317/76 , C07K2317/77 , C07K2317/92
摘要： The present invention relates to anti-cKIT antibodies, antibody fragments, antibody drug conjugates, and their uses for the treatment of cancer.

3. 发明授权

US09479823B2 Transmitting device and receiving device 有权
标题翻译：发射装置和接收装置
公开(公告)号：US09479823B2
公开(公告)日：2016-10-25
申请号：US11607622
申请日：2006-12-01
申请人： Hans-Juergen Busch , Rainer Bauereiss , Thomas Huber
发明人： Hans-Juergen Busch , Rainer Bauereiss , Thomas Huber
IPC分类号： H04N11/04 , H04N21/434 , H04N19/159 , H04N19/172 , H04N19/61 , H04N19/107 , H04N19/40
CPC分类号： H04N21/4344 , H04N19/107 , H04N19/159 , H04N19/172 , H04N19/40 , H04N19/61
摘要： A transmitting device, a receiving device, and a method for transmitting and a method for receiving data streams, in particular video streams, are described. The transmitting device for data streams, in particular video data, has at least one unit. This at least one unit is designed for subdividing the data streams into sections, the sections into packets, and for providing the sections in a sequence that is the reverse of an original sequence and the packets in an original sequence.
摘要翻译：描述了发送设备，接收设备和用于发送的方法以及用于接收数据流的方法，特别是视频流。用于数据流的发送设备，特别是视频数据，具有至少一个单元。该至少一个单元被设计用于将数据流细分成多个部分，将这些部分分组成分组，并且用于以与原始序列相反的序列和原始序列中的分组来提供这些部分。

4. 发明申请

US20160137730A1 ANTIBODY DRUG CONJUGATES 有权
标题翻译：抗体药物联合用药
公开(公告)号：US20160137730A1
公开(公告)日：2016-05-19
申请号：US14940961
申请日：2015-11-13
申请人： Tinya ABRAMS , Steven Bruce Cohen , Jason Damiano , Clemens Dürr , Thomas Huber , Daniel Menezes , Kathy Miller , Katherine Rendahl , Jean-Michel Rene Rondeau
发明人： Tinya ABRAMS , Steven Bruce Cohen , Jason Damiano , Clemens Dürr , Thomas Huber , Daniel Menezes , Kathy Miller , Katherine Rendahl , Jean-Michel Rene Rondeau
IPC分类号： C07K16/28 , G01N33/574 , A61K47/48 , C07K16/30 , A61K31/5365
CPC分类号： C07K16/28 , A61K31/5365 , A61K47/6803 , A61K47/6849 , A61K47/6851 , C07K16/30 , C07K2299/00 , C07K2317/21 , C07K2317/24 , C07K2317/33 , C07K2317/51 , C07K2317/515 , C07K2317/52 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/622 , C07K2317/73 , C07K2317/732 , C07K2317/76 , C07K2317/77 , C07K2317/92 , C07K2319/00 , G01N33/57492 , G01N2333/705
摘要： This application discloses anti-P-cadherin antibodies, antigen binding fragments thereof, and antibody drug conjugates of said antibodies or antigen binding fragments. The invention also relates to methods of treating cancer using the antibodies, antigen binding fragments, and antibody drug conjugates. Also disclosed herein are methods of making the antibodies, antigen binding fragments, and antibody drug conjugates, and methods of using the antibodies and antigen binding fragments as diagnostic reagents.
摘要翻译：本申请公开了抗P-钙粘蛋白抗体，其抗原结合片段和所述抗体或抗原结合片段的抗体药物偶联物。本发明还涉及使用抗体，抗原结合片段和抗体药物缀合物治疗癌症的方法。本文还公开了制备抗体，抗原结合片段和抗体药物缀合物的方法，以及使用抗体和抗原结合片段作为诊断试剂的方法。

5. 发明申请

US20130297065A1 Loading System for an Aircraft and Method for Conveying a Piece of Cargo on a Cargo Deck 有权
标题翻译：飞机装载系统和货物在货物甲板上运送的方法
公开(公告)号：US20130297065A1
公开(公告)日：2013-11-07
申请号：US13979611
申请日：2012-01-18
申请人： Thomas Huber
发明人： Thomas Huber
IPC分类号： B64D9/00 , B64C1/22
CPC分类号： B64D9/00 , B64C1/22
摘要： The invention concerns a loading system for an aircraft, wherein the loading system comprises a control computer; a multiplicity of cargo conveying devices for conveying a piece of cargo on a cargo loading deck of the aircraft, wherein to control the cargo conveying devices, the control computer is communicatively connected with the cargo conveying devices; at least one input device which is communicatively connected with the control computer to transfer user inputs to the control computer. An aspect of the invention is that the one input device may be formed as a touchscreen.
摘要翻译：本发明涉及一种用于飞机的加载系统，其中装载系统包括控制计算机; 用于将一件货物运送在飞机的货物装载甲板上的多个货物输送装置，其中为了控制货物输送装置，控制计算机与货物输送装置通信地连接; 至少一个输入设备，其与所述控制计算机通信地连接以将用户输入传送到所述控制计算机。本发明的一个方面是一个输入装置可以形成为触摸屏。

6. 发明申请

US20130031582A1 AUTOMATIC LOCALIZATION OF ADVERTISEMENTS 审中-公开
标题翻译：自动定位广告
公开(公告)号：US20130031582A1
公开(公告)日：2013-01-31
申请号：US13621794
申请日：2012-09-17
申请人： John Tinsman , Thomas Huber , Thomas Lemmons , Ian Zenoni
发明人： John Tinsman , Thomas Huber , Thomas Lemmons , Ian Zenoni
IPC分类号： H04N21/236
CPC分类号： G06Q30/0275 , H04N21/2353 , H04N21/237 , H04N21/4316 , H04N21/8583
摘要： In various example embodiments, a system and method for automatic localization of advertisements is provided. In example embodiments, a transmission signal is received. A portion of the transmission signal is identified. A determination of whether localized advertisement data corresponds to the identified portion is performed. Localized advertisement data that correspond to the identified portion of the transmission signal is retrieved. The localized advertisement data is then inserted into the identified portion of the transmission signal to generate an altered signal. The altered signal is transmitted to a user device.
摘要翻译：在各种示例性实施例中，提供了用于广告的自动定位的系统和方法。在示例实施例中，接收发送信号。识别发送信号的一部分。执行本地化广告数据对应于所识别的部分的确定。检索对应于发送信号的识别部分的本地化广告数据。然后将本地化的广告数据插入到发送信号的识别部分中，以产生改变的信号。改变的信号被传送到用户设备。

7. 发明申请

US20130024293A1 SYSTEM AND METHOD FOR OFFERING AND BILLING ADVERTISEMENT OPPORTUNITIES 审中-公开
标题翻译：提供和打击广告机会的系统和方法
公开(公告)号：US20130024293A1
公开(公告)日：2013-01-24
申请号：US13621782
申请日：2012-09-17
申请人： John Tinsman , Thomas Huber , Thomas Lemmons , Ian Zenoni
发明人： John Tinsman , Thomas Huber , Thomas Lemmons , Ian Zenoni
IPC分类号： G06Q30/02
CPC分类号： G06Q30/0275
摘要： In various example embodiments, a system and method for offering and billing advertisement opportunities are provided. In example embodiments, an advertisement opportunity in media to be communicated to a user device associated with a viewer is identified. Attributes of the advertisement opportunity are determined. Based on these attributes, a value to assign to the advertisement opportunity is determined. The advertisement opportunity is offered to a potential advertiser based on the assigned value determined using the attributes of the advertisement opportunity.
摘要翻译：在各种示例实施例中，提供了用于提供和计费广告机会的系统和方法。在示例实施例中，识别要传送到与观看者相关联的用户设备的媒体中的广告机会。确定广告机会的属性。基于这些属性，确定分配给广告机会的值。基于使用广告机会的属性确定的分配值，向潜在广告商提供广告机会。

8. 发明申请

US20130019261A1 SYSTEM AND METHOD FOR PROVIDING INTERACTIVE ADVERTISEMENT 有权
标题翻译：提供交互式广告的系统和方法
公开(公告)号：US20130019261A1
公开(公告)日：2013-01-17
申请号：US13621733
申请日：2012-09-17
申请人： Thomas Huber , Thomas Lemmons , Ian Zenoni , Debra Hensgen
发明人： Thomas Huber , Thomas Lemmons , Ian Zenoni , Debra Hensgen
IPC分类号： H04N21/80
CPC分类号： G06Q30/08 , G06Q30/0269
摘要： In example embodiments, a system and method for providing interactive advertisement is provided. In some embodiments, a component causes a video program having an interactive advertisement to be displayed to a user on a display screen. The interactive advertisement includes an enhanced content activator. In response to activation of the enhanced content activator by the user, enhanced advertisement information including at least one trigger is provisioned. The enhanced advertisement information is then caused to be displayed with the video program and the interactive advertisement. A selection by the user of the at least one trigger associated with the enhanced advertisement information is monitored. In response to selection of the at least one trigger, access to further content associated with the enhanced content information is provided.
摘要翻译：在示例实施例中，提供了一种用于提供交互式广告的系统和方法。在一些实施例中，组件使得具有交互式广告的视频节目在显示屏幕上显示给用户。互动广告包括增强内容激活器。响应于用户激活增强内容激活器，提供包括至少一个触发的增强广告信息。然后使增强的广告信息与视频节目和交互式广告一起显示。监视与增强的广告信息相关联的至少一个触发器的用户的选择。响应于对至少一个触发器的选择，提供对与增强内容信息相关联的更多内容的访问。

9. 发明授权

US08226034B2 Cargo deck and a method for assembling said deck 有权
标题翻译：货物甲板和组装甲板的方法
公开(公告)号：US08226034B2
公开(公告)日：2012-07-24
申请号：US10565082
申请日：2004-07-15
申请人： Thomas Huber , Richard Holzner
发明人： Thomas Huber , Richard Holzner
IPC分类号： B64C1/22
CPC分类号： B64C1/068 , B64C1/061 , B64C1/064 , B64C1/065 , B64C1/18 , B64C1/20 , B64C1/22 , B64C2211/00 , B64D9/00 , B64D11/02 , B64D2011/0046 , Y10T29/49826
摘要： An aircraft cargo deck is provided to receive loads stored in the cargo compartment. The aircraft comprises an outer skin to which longitudinal beams are secured, preferably via ribs attached to the outer skin. To simplify the construction and the assembly of the cargo deck, it is composed of a plurality of floor modules, which are fixed within the cargo compartment and which are mounted on the longitudinal beams.
摘要翻译：提供飞机货物甲板以接收储存在货舱中的负载。飞行器包括外皮，优选地通过连接到外皮的肋条固定纵梁。为了简化货物甲板的结构和组装，它由多个地板模块组成，它们固定在货舱内并安装在纵梁上。

10. 发明申请

US20120122630A1 METHOD AND DEVICE FOR STARTING AN INTERNAL COMBUSTION ENGINE OF A HYBRID DRIVE TRAIN 有权
标题翻译：用于启动混合动力车内燃机的方法和装置
公开(公告)号：US20120122630A1
公开(公告)日：2012-05-17
申请号：US13001163
申请日：2009-04-28
申请人： Thomas Huber , Michael Lehner , Oliver Kaefer , Karsten Mann , Anja Winter-Mann
发明人： Thomas Huber , Michael Lehner , Oliver Kaefer , Karsten Mann , Anja Winter-Mann
IPC分类号： B60W20/00 , B60W10/02
CPC分类号： B60W20/30 , B60K6/365 , B60K6/48 , B60K6/547 , B60L2240/421 , B60L2240/441 , B60W10/02 , B60W10/06 , B60W10/08 , B60W20/00 , B60W2510/0638 , B60W2510/0685 , B60W2510/081 , F02D2400/16 , F02N5/04 , F02N11/08 , F02N11/0814 , F02N11/0851 , F02N11/0866 , F02N15/022 , F02N99/006 , Y02T10/48 , Y02T10/6221 , Y02T10/6286 , Y02T10/642 , Y10T477/26 , Y10T477/65
摘要： A method and a device are described for starting an internal combustion engine of a hybrid drive train, having an internal combustion engine and at least one additional machine, in particular an electric machine, a separating clutch, which is situated between the internal combustion engine and the additional machine, and a crankshaft angle sensor for detecting the instantaneous crankshaft angle of the internal combustion engine being provided. Arrangements are provided to perform the following operations to start the internal combustion engine when a high-voltage battery is essentially discharged, including a) the separating clutch is or has already been disengaged, b) the additional machine is accelerated, c) after conclusion of the acceleration operation of the additional machine, the separating clutch is engaged, so that the internal combustion engine is also accelerated, d) as soon as the crankshaft angle sensor system supplies a favorable crankshaft angle, the internal combustion engine is started by direct start.
摘要翻译：描述了一种用于启动混合动力传动系的内燃机的方法和装置，所述内燃机具有内燃机和至少一个额外的机器，特别是电机，分离离合器，其位于内燃机和附加机器和用于检测内燃机的瞬时曲轴角度的曲轴角度传感器。提供了安排，以便在高压电池基本上排放时执行以下操作来启动内燃机，包括a）分离离合器已经或已经脱离，b）加速机加速，c）在结束后附加机器的加速操作，分离离合器接合，使得内燃机也加速，d）一旦曲轴角度传感器系统提供有利的曲轴角度，则内燃机通过直接启动启动。

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