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1. 发明授权

US5978709A Pacemaker system with improved techniques for preventing and suppressing atrial arrhythmias 失效
标题翻译：起搏器系统具有改进的预防和抑制心房心律失常的技术
公开(公告)号：US5978709A
公开(公告)日：1999-11-02
申请号：US98162
申请日：1998-06-16
申请人： Malcolm J. S. Begemann , Johannes S. Van Der Veen , Xander Evers
发明人： Malcolm J. S. Begemann , Johannes S. Van Der Veen , Xander Evers
IPC分类号： A61N1/362
CPC分类号： A61N1/3622
摘要： There is provided a pacing system having special functions for treating the patient's atrium with atrial pacing so as to reduce the probability of occurrence of dangerous atrial arrhythmias. The pacemaker of the system provides for atrial Pace.sub.-- Conditioning, whereby the patient's normal intrinsic atrial rate is overridden by higher rate pacing whenever a predetermined sequence of intrinsic heartbeats is sensed. The pacemaker also provides for special pacing routines following the detection of one or more PACs. The PAC response routines include pacing at an elevated rate for a predetermined time or number of beats, and smoothing out pacing intervals for one or several cycles following the occurrence of a PAC. The pacemaker also includes a post-exercise function, for overtaking the intrinsic rate and pacing the heart following exercise, the pacing being in accordance with a predetermined program which holds a relatively higher rate longer than normal post-exercise, so as to provide enhanced blood flow to the cardiac tissue and prevent the onset of ischemia.
摘要翻译：提供了一种具有特殊功能的起搏系统，用于以心房起搏治疗患者心房，以降低危险心房心律失常的发生概率。系统的起搏器提供心房心律调节，从而每当检测到预定的内在心跳序列时，患者的正常固有心房率被更高的速率起搏所覆盖。起搏器还在检测到一个或多个PAC之后提供特殊的起搏程序。 PAC响应例程包括以提高的速率起搏一段预定时间或次数的节拍，以及在出现PAC之后平滑起搏间隔一个或多个周期。起搏器还包括运动后功能，用于超越内在速度，并且在运动后起搏心脏，起搏是按照预定程序进行的，该程序比运动后正常运行的时间要长得多，从而提供增强的血液流向心脏组织并防止缺血发作。

2. 发明申请

US20090270729A1 Implantable Device and Method for Monitoring Venous Diameter 有权
标题翻译：可植入装置及监测静脉直径的方法
公开(公告)号：US20090270729A1
公开(公告)日：2009-10-29
申请号：US12109408
申请日：2008-04-25
申请人： Giorgio Corbucci , Josephus P.A. Smit , Johannes S. Van Der Veen , Geert Van Lembergen , Marinus C.J. Verschelling
发明人： Giorgio Corbucci , Josephus P.A. Smit , Johannes S. Van Der Veen , Geert Van Lembergen , Marinus C.J. Verschelling
IPC分类号： A61B5/0205 , A61B5/053 , A61B8/08
CPC分类号： A61B5/1076 , A61B5/02007 , A61B5/02028 , A61B5/0205 , A61B5/02152 , A61B5/02158 , A61B5/0538 , A61B5/0816 , A61B5/7275 , A61B5/7278 , A61B5/7282 , A61B8/0891 , A61B8/12
摘要： An implantable medical device system and associated method receive a signal from an implantable sensor operatively positioned relative to a vein, the signal being responsive to changes in a diameter of the vein. A diameter of the vein is determined in response to the sensor signal and used in estimating central venous pressure (CVP).
摘要翻译：植入式医疗装置系统和相关方法从相对于静脉可操作地定位的可植入传感器接收信号，所述信号响应于静脉直径的变化。根据传感器信号确定静脉的直径，并用于估计中心静脉压（CVP）。

3. 发明授权

US08814798B2 Implantable device and method for monitoring venous diameter 有权
标题翻译：植入式装置及监测静脉直径的方法
公开(公告)号：US08814798B2
公开(公告)日：2014-08-26
申请号：US12109408
申请日：2008-04-25
申请人： Giorgio Corbucci , Josephus P. A. Smit , Johannes S. Van Der Veen , Geert Van Lembergen , Marinus C. J. Verschelling
发明人： Giorgio Corbucci , Josephus P. A. Smit , Johannes S. Van Der Veen , Geert Van Lembergen , Marinus C. J. Verschelling
IPC分类号： A61B5/0205 , A61B5/053 , A61B8/08 , A61B5/107 , A61B5/0215
CPC分类号： A61B5/1076 , A61B5/02007 , A61B5/02028 , A61B5/0205 , A61B5/02152 , A61B5/02158 , A61B5/0538 , A61B5/0816 , A61B5/7275 , A61B5/7278 , A61B5/7282 , A61B8/0891 , A61B8/12
摘要： An implantable medical device system and associated method receive a signal from an implantable sensor operatively positioned relative to a vein, the signal being responsive to changes in a diameter of the vein. A diameter of the vein is determined in response to the sensor signal and used in estimating central venous pressure (CVP).
摘要翻译：植入式医疗装置系统和相关方法从相对于静脉可操作地定位的可植入传感器接收信号，所述信号响应于静脉直径的变化。根据传感器信号确定静脉的直径，并用于估计中心静脉压（CVP）。

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