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1. 发明授权

US12036114B2 Stented prosthetic heart valve having a wrap and delivery devices 有权
公开(公告)号：US12036114B2
公开(公告)日：2024-07-16
申请号：US17116431
申请日：2020-12-09
申请人： Medtronic Vascular, Inc.
发明人： Michael Bateman , Cynthia Clague , Jeffrey Sandstrom , Joel Racchini , James R. Keogh
IPC分类号： A61F2/24 , A61F2/844 , A61F2/852
CPC分类号： A61F2/2418 , A61F2/2409 , A61F2/2436 , A61F2/2439 , A61F2/844 , A61F2/852 , A61F2220/0025 , A61F2220/0033 , A61F2250/0069
摘要： Stented prosthetic heart valves comprising a stent frame having a compressed arrangement for delivery within a patient's vasculature and an expanded arrangement for deployment within a native heart valve. The stented prosthetic heart valves including a paravalvular leakage prevention or mitigation wrap that encircles a stent frame and is formed of a flexible material having a variable diameter defined by a greatest distance between the wrap and the stent frame. The wrap further includes a first end coupled to the stent frame and an opposing second end that is not coupled to the stent frame, wherein the wrap can selectively enlarge its diameter in situ via movement of the second end. Devices for and methods of selectively deploying the wrap are also disclosed.

2. 发明授权

US11903828B2 Transcatheter prosthetic heart valve delivery system with lateral offset control 有权
公开(公告)号：US11903828B2
公开(公告)日：2024-02-20
申请号：US16934119
申请日：2020-07-21
申请人： Medtronic Vascular, Inc.
发明人： Jill Mendelson , Michele Silver , Michael Gloss , Timothy Groen , Paul Rothstein , Jeffrey Sandstrom , Phil Haarstad , Joel Racchini , David Blaeser
IPC分类号： A61F2/24 , A61F2/95 , A61F2/07 , A61F2/962
CPC分类号： A61F2/2427 , A61F2/2436 , A61F2/2439 , A61F2/95 , A61F2/07 , A61F2/243 , A61F2/2418 , A61F2/9517 , A61F2/962 , A61F2230/0063
摘要： Delivery devices for a stented prosthetic heart valve. The delivery device includes a spindle, at least one cord, and a lateral control feature. The cord is tensioned to crimp the prosthesis to a compressed condition for delivery to a target site. Tension is lessened to allow the prosthesis to self-expand. In a tethered and expanded state in which the prosthesis has self-expanded and is connected to the spindle by the cord, the lateral control feature directs the spindle to a prescribed location relative to the prosthesis appropriate for a functional evaluation of the prosthesis. In some embodiments, the spindle is directed to a center of the prosthesis; in other embodiments, the spindle is held at a commissure of the prosthesis. The lateral control features of the present disclosure assume numerous forms.

3. 发明授权

US10420642B2 Transcatheter stented prosthetic heart valve delivery devices 有权
公开(公告)号：US10420642B2
公开(公告)日：2019-09-24
申请号：US15069102
申请日：2016-03-14
申请人： Medtronic Vascular, Inc.
发明人： Michael Gloss , Timothy Groen , Paul Rothstein , Jeffrey Sandstrom , Phil Haarstad , Joel Racchini , Tuan Doan
IPC分类号： A61F2/24
摘要： Disclosed embodiments and methods provide solutions for coupling and decoupling of a delivery device from a stented prosthetic heart valve with one or more release mechanisms. In situations when one or more sutures get tangled or caught upon attempted retraction of the delivery device and sutures after deployment of the stented prosthetic heart valve, a secondary release mechanism can be provided to sever the suture(s) or release the suture(s) from the delivery device. Exemplary secondary release mechanisms include high resistance inserts, cutters and balloon expandable devices. Methods of releasing the sutures from the delivery device or severing the suture(s) are also disclosed.

4. 发明申请

US20190282363A1 DEVICES AND METHODS FOR TRANSCATHETER VALVE LOADING AND IMPLANTATION 审中-公开
公开(公告)号：US20190282363A1
公开(公告)日：2019-09-19
申请号：US16427564
申请日：2019-05-31
申请人： Medtronic Vascular, Inc.
发明人： Martha Barajas-Torres , Kevin Mauch , Jeffrey Sandstrom , Jill Mendelson , Don Tran
IPC分类号： A61F2/24
摘要： The present disclosure relates to numerous devices and methods for transcatheter stented prosthetic heart valve loading and delivery. Such devices and methods reduce suture tangling and also provide the ability to adjust the stented prosthetic heart valve expansion and contraction prior to the final release of the stented prosthetic heart valve from the delivery device.

5. 发明申请

US20170348099A1 TRANSCATHETER PROSTHETIC HEART VALVE DELIVERY SYSTEM WITH LATERAL OFFSET CONTROL 审中-公开
公开(公告)号：US20170348099A1
公开(公告)日：2017-12-07
申请号：US15614890
申请日：2017-06-06
申请人： Medtronic Vascular, Inc.
发明人： Jill Mendelson , Michele Silver , Michael Gloss , Timothy Groen , Paul Rothstein , Jeffrey Sandstrom , Paul Haarstad , Joel Racchini , David Blaeser
IPC分类号： A61F2/24 , A61F2/95 , A61F2/962 , A61F2/07
摘要： Delivery devices for a stented prosthetic heart valve. The delivery device includes a spindle, at least one cord, and a lateral control feature. The cord is tensioned to crimp the prosthesis to a compressed condition for delivery to a target site. Tension is lessened to allow the prosthesis to self-expand. In a tethered and expanded state in which the prosthesis has self-expanded and is connected to the spindle by the cord, the lateral control feature directs the spindle to a prescribed location relative to the prosthesis appropriate for a functional evaluation of the prosthesis. In some embodiments, the spindle is directed to a center of the prosthesis; in other embodiments, the spindle is held at a commissure of the prosthesis. The lateral control features of the present disclosure assume numerous forms.

6. 发明申请

US20170165067A1 DEVICES AND METHODS FOR TRANSCATHETER VALVE LOADING AND IMPLANTATION 审中-公开
公开(公告)号：US20170165067A1
公开(公告)日：2017-06-15
申请号：US15376739
申请日：2016-12-13
申请人： Medtronic Vascular, Inc.
发明人： Martha Barajas-Torres , Kevin Mauch , Jeffrey Sandstrom , Jill Mendelson , Don Tran
IPC分类号： A61F2/24
CPC分类号： A61F2/2439 , A61F2/2415 , A61F2/2418 , A61F2002/9511
摘要： The present disclosure relates to numerous devices and methods for transcatheter stented prosthetic heart valve loading and delivery. Such devices and methods reduce suture tangling and also provide the ability to adjust the stented prosthetic heart valve expansion and contraction prior to the final release of the stented prosthetic heart valve from the delivery device.

7. 发明申请

US20160262883A1 DELIVERY DEVICE FOR PROSTHETIC HEART VALVE WITH CAPSULE ADJUSTMENT DEVICE 审中-公开
标题翻译：用于具有胶囊调节装置的前置心脏瓣膜的输送装置
公开(公告)号：US20160262883A1
公开(公告)日：2016-09-15
申请号：US14656838
申请日：2015-03-13
申请人： Medtronic Vascular, Inc.
发明人： Jeffrey Sandstrom
IPC分类号： A61F2/24
摘要： A delivery device for percutaneously delivering a stented prosthetic heart includes a sheath, a handle, and adjustment device including a fine adjustment mechanism, and an outer stability shaft. The sheath defines a lumen and is configured to compressively constrain the stented prosthetic heart valve. The handle is coupled to the proximal portion of the sheath and includes an actuator mechanism coupled to a proximal portion of the sheath that is configured to selectively move the sheath relative to the housing to release the stented prosthetic heat valve. The adjustment device is coupled to the handle and includes an adjustment lumen through which the sheath and the handle slidably extend. The outer stability shaft is coupled to the adjustment device. The fine adjustment mechanism is configured to selectively move the handle and the sheath relative to the adjustment device and the outer stability shaft.
摘要翻译：用于经皮递送支架假体心脏的输送装置包括护套，手柄和包括微调机构和外稳定轴的调节装置。护套限定内腔并且构造成压缩地约束支架假体心脏瓣膜。手柄联接到护套的近端部分并且包括联接到护套的近侧部分的致动器机构，其构造成相对于壳体选择性地移动护套以释放支架的假体热阀。调节装置联接到手柄并且包括调节内腔，护套和手柄通过该调节内腔可滑动地延伸。外稳定轴与调节装置连接。微调机构配置成相对于调节装置和外稳定轴选择性地移动手柄和护套。

8. 发明授权

US12004951B2 Delivery device for prosthetic heart valve with capsule adjustment device 有权
公开(公告)号：US12004951B2
公开(公告)日：2024-06-11
申请号：US18165268
申请日：2023-02-06
申请人： MEDTRONIC VASCULAR, INC.
发明人： Jeffrey Sandstrom
IPC分类号： A61F2/24 , A61F2/95
CPC分类号： A61F2/2436 , A61F2/95 , A61F2/2427 , A61F2/9517
摘要： A delivery device for percutaneously delivering a stented prosthetic heart includes a sheath, a handle, and adjustment device including a fine adjustment mechanism, and an outer stability shaft. The sheath defines a lumen and is configured to compressively constrain the stented prosthetic heart valve. The handle is coupled to the proximal portion of the sheath and includes an actuator mechanism coupled to a proximal portion of the sheath that is configured to selectively move the sheath relative to the housing to release the stented prosthetic heat valve. The adjustment device is coupled to the handle and includes an adjustment lumen through which the sheath and the handle slidably extend. The outer stability shaft is coupled to the adjustment device. The fine adjustment mechanism is configured to selectively move the handle and the sheath relative to the adjustment device and the outer stability shaft.

9. 发明授权

US11701228B2 Flexible canopy valve repair systems and methods of use 有权
公开(公告)号：US11701228B2
公开(公告)日：2023-07-18
申请号：US17339353
申请日：2021-06-04
申请人： MEDTRONIC VASCULAR, INC.
发明人： Matthew Genovese , Jeffrey Sandstrom , Russell Pribanic , Thomas McPeak , Vania Lee , Dermot O'Brien , James Calvin Allan
IPC分类号： A61F2/24 , A61B17/04 , A61B17/00
CPC分类号： A61F2/2454 , A61F2/2457 , A61F2/2463 , A61B17/0401 , A61B2017/00243 , A61F2/2412 , A61F2230/0095 , A61F2250/0018
摘要： A system for treating valvular regurgitation in a heart valve includes a flexible canopy and an elongated tether including an elastic portion and an inelastic portion. When the system is in a deployed configuration, a proximal end of the flexible canopy is coupled to an annulus of the heart valve and a distal end of the elongated tether is coupled to a ventricle. The flexible canopy is configured to overlay a first native leaflet of the heart valve, and tension on the elongated tether is applied and/or adjusted to prevent the first leaflet from prolapsing, to maximize coaptation of the flexible canopy with a second native leaflet of the heart valve, and to minimize regurgitation of the heart valve.

10. 发明申请

US20220287839A1 HEART VALVE REPAIR 有权
公开(公告)号：US20220287839A1
公开(公告)日：2022-09-15
申请号：US17635274
申请日：2020-08-04
申请人： Medtronic Vascular, Inc.
发明人： Matthew E. Genovese , Vania Lee , Russell Pribanic , Thomas J. McPeak , Jeffrey Sandstrom , Dermot O'Brien , James Calvin Allan
IPC分类号： A61F2/24
摘要： A medical system includes a catheter navigable through vasculature of patient to introduce a valve clip configured to join the edges of heart valve leaflets. The valve clip includes a deformable wire configured to engage valve leaflets, the wire extending from a first wire portion to a second wire portion. The catheter includes a handle having control members, an elongate body defining a lumen extending from the handle to a distal opening, and first and second delivery devices operatively coupled to a control member and extending through the lumen to the distal opening. Each delivery device is configured to releasably couple to a portion of the wire and moveable relative to the distal opening. The delivery devices are controllable at the handle to move the valve clip between an extended configuration and a contracted configuration to engage the valve leaflets.

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